Claims
- 1. A compound of the formula: ##STR5## wherein R.sup.1 is aryl which is substituted with substituent(s) selected from the group consisting of hydroxy(lower)alkyl, lower alkylenedioxy, carboxy, esterified carboxy, carbamoyl, lower alkanoyloxy, aryloxy and lower alkoxy substituted with acyl or lower alkoxy,
- R.sup.2 is halogen, halo(lower)alkyl, cyano or acyl, and
- R.sup.3 is aryl substituted with lower alkylthio, lower alkylsulfinyl or lower alkylsulfonyl;
- R.sup.1 is phenyl substituted with methoxy,
- R.sup.2 is difluoromethyl and
- R.sup.3 is phenyl substituted with methylsulfinyl; or
- R.sup.1 is phenyl which is substituted with lower alkylthio, lower alkylsulfinyl or lower alkylsulfonyl,
- R.sup.2 is difluoromethyl and
- R.sup.3 is phenyl substituted with methoxy.
- 2. A compound of the formula: ##STR6## wherein R.sup.1 is phenyl substituted with methoxy,
- R.sup.2 is difluoromethyl and
- R.sup.3 is phenyl substituted with methylsulfinyl.
- 3. The compound of claim 1, which is 3-(difluoromethyl)-1-(4-methoxyphenyl)-5-�4-methylsulfinyl)phenyl!pyrazole.
- 4. A pharmaceutical composition comprising a compound of claim 1, as an active ingredient, in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient.
Priority Claims (2)
Number |
Date |
Country |
Kind |
9202442 |
Feb 1992 |
GBX |
|
9220427 |
Sep 1992 |
GBX |
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Parent Case Info
This is a continuation of application Ser. No 08/413,939 filed on Mar. 30, 1995, now U.S. Pat. No. 5,550,447, which is a continuation of Ser. No. 08/000,297 filed on Jan. 4, 1993, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5134142 |
Matsuo et al. |
Jul 1992 |
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Continuations (2)
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Number |
Date |
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Parent |
413939 |
Mar 1995 |
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Parent |
000297 |
Jan 1993 |
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