Claims
- 1. A modified protein, polypeptide, polysaccharide or polysaccharide derivative containing amino groups and being soluble in aqueous liquids, wherein at least one amino group (--NH.sub.2) of said protein, polypeptide, polysaccharide or polysaccharide derivative has been converted to a group of the formula ##STR26## wherein R.sup.1 is 2-pyridyl, 5-nitro-2-pyridyl or 4-pyridyl, A is a hydrocarbon residue having 1-10 carbon atoms and X is O or NH, by reaction with a compound having the formula
- R.sup.1 --S--S--A--Z
- wherein R.sup.1 and A are as defined above and Z is from the group ##STR27## or acid addition salts of the last mentioned group, where n is 2 or 3, R.sup.1 has the same significance as R.sup.1 above and is equal thereto, and R.sup.2 is methyl or ethyl.
- 2. A modified protein, polypeptide, polysaccharide or polysaccharide derivative containing amino groups according to claim 1, wherein A is a hydrocarbon residue containing 1-6 carbon atoms.
- 3. A modified protein, polypeptide, polysaccharide or polysaccharide derivative containing amino groups and being soluble in aqueous liquids, wherein at least one amino group (--NH.sub.2) of said protein, polypeptide, polysaccharide or polysaccharide derivative has been converted to a group of the formula ##STR28## wherein R.sup.1 is 2-pyridyl,5-nitro-2-pyridyl or 4-pyridyl and A is a hydrocarbon residue of 1-6 carbon atoms, by reaction with a compound having the formula
- R.sup.1 --S--S--A--Z
- wherein R.sup.1 and A are as defined above and Z is either ##STR29## where n is 2 or 3 and R.sup.1 has the same significance as R.sup.1 above and is equal thereto.
- 4. A modified protein, polypeptide, polysaccharide or polysaccharide derivative containing amino groups according to claim 3 wherein A is --CH.sub.2 --CH.sub.2 --.
- 5. A modified protein, polypeptide, polysaccharide or polysaccharide derivative containing amino groups according to claim 4 wherein R.sup.1 is 2-pyridyl.
RELATED APPLICATIONS
This application is a continuation of Ser. No. 238,853 (filed Feb. 27, 1981), now abandoned, which in turn was a continuation of Ser. No. 98,302 (filed Nov. 28, 1979), now abandoned, which in turn was a continuation of Ser. No. 946,140 (filed Sept. 27, 1978), now abandoned, which in turn was a division of Ser. No. 882,546 (filed Mar. 2, 1978), now U.S. Pat. No. 4,149,033. The benefits of 35 USC 120 are claimed relative to these applications.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4149003 |
Carlsson et al. |
Apr 1979 |
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Non-Patent Literature Citations (3)
Entry |
Chem. Abstracts vol. 90, 1979, 18765w, Carlsson et al., effective date 9/78. |
Chem. Abstracts vol. 90, 1979, 181773f, Carlsson et al., effective date 1978. |
Biochemical J., Sep., 1978, 173(3), 723-737, Carlsson et al. |
Divisions (1)
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Number |
Date |
Country |
Parent |
882546 |
Mar 1978 |
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Continuations (3)
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Number |
Date |
Country |
Parent |
238853 |
Feb 1981 |
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Parent |
98302 |
Nov 1979 |
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Parent |
946140 |
Sep 1978 |
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