Claims
- 1. A pyridine derivative of the formula (IV): ##STR65## wherein R.sub.1 and R.sub.2 are the same or different and are a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkoxy group, hydroxy group, nitro group, cyano group, amino group, carbamoyl group, an acylamino group, a lower alkylamino group, a lower alkenylamino group or an aralkylamino group, X is an oxygen atom or --S(O).sub.n --, wherein n is 0, 1 or 2, A is a bivalent C.sub.1-15 hydrocarbon residue, Y is an oxygen or sulfur atom, a group of the formula: ##STR66## is an optionally substituted benzene ring, B.sub.2 is --C(S)--O--, or a salt or solvent thereof.
- 2. A pyridine derivative according to claim 1, wherein R.sub.1 and R.sub.2 are the same or different and are a hydrogen atom, amino group or an acylamino group, X is an oxygen or sulfur atom, A is a bibalent C.sub.1-6 hydrocarbon
- 3. A pyridine derivative according to claim 2, wherein R.sub.1 and R.sub.2 are a hydrogen atom, A is a C.sub.1-4 alkylene.
- 4. The pyridine derivative according to claim 1 which is 3-[3-(4-pyridylthio)propyl]-2H-1,3-benzoxazine-2-thion-4(3H)-one.
- 5. The pyridine derivative according to claim 1 which is 3-[4-(4-pyridylthio)butyl]-2H-1,3-benzoxazine-2-thion-4(3H)-one.
- 6. A pharmaceutical composition which comprise the compound of claim 1.
- 7. A method for providing antiinflammatory activity which comprises administering an effective amount of the pharmaceutical composition of claim 6.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3-105691 |
May 1991 |
JPX |
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Parent Case Info
This application is a division of application Ser. No. 08/081,181, filed Jun. 24, 1993, now U.S. Pat. No. 5,389,658 which is a divisional of application Ser. No. 07/880,614 filed May 7,1992 now U.S. Pat. No. 5,246,948.
US Referenced Citations (12)
Foreign Referenced Citations (1)
Number |
Date |
Country |
2034712 |
Jun 1980 |
GBX |
Non-Patent Literature Citations (2)
Entry |
Chemical Abstracts, vol. 85, No. 14, Oct. 4, 1976, p. 325, Abstract 99178d. |
Chemical Abstracts, vol. 61, No. 1, Jul. 1, 1964, Abstract 638g. |
Divisions (2)
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Number |
Date |
Country |
Parent |
81181 |
Jun 1993 |
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Parent |
880641 |
May 1992 |
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