Claims
- 1. A pyridonecarboxylic acid derivative of the following general formula (1): ##STR8## wherein R.sup.1 is a hydrogen atom or carboxy protecting group, R.sup.2 is a nitro or substituted or unsubstituted amino group, R.sup.3 is a halogen atom, each of R.sup.4 and R.sup.5, which may be the same or different, is a hydrogen atom, halogen atom, lower alkyl group or lower alkoxy group with the proviso that both of R.sup.4 and R.sup.5 are not simultaneously hydrogen atoms, R.sup.6 is a hydrogen atom, halogen atom, hydroxy group, lower alkyl group or amino group, R.sup.7 is a hydrogen atom or halogen atom, A is a nitrogen atom or --CX.dbd. wherein X is a hydrogen atom, halogen atom, lower alkyl group or lower alkoxy group, and Z is a halogen atom or a saturated cyclic amino group which may have a substituent, or a salt thereof.
- 2. An antibacterial agent comprising a pyridonecarboxylic acid derivative or a salt thereof as set forth in claim 1 as an active ingredient and a pharmaceutically acceptable carrier therefor.
- 3. A method of treating a person infected with bacteria by administering an effective amount of the compound of claim 1 to a person in need thereof.
- 4. A method of treating an animal infected with bacteria by administering an effective amount of the compound of claim 1 to an animal in need thereof.
- 5. A method of treating a person infected with a virus by administering an effective amount of the compound of claim 1 to a person in need thereof.
- 6. A method of treating an animal infected with a virus by administering an effective amount of the compound of claim 1.
- 7. A pyridonecarboxylic acid derivative of the following general formula (1): ##STR9## wherein R.sup.1 is a hydrogen atom or carboxy protecting group, R.sup.2 is a nitro or substituted or unsubstituted amino group, R.sup.3 is a halogen atom, each of R.sup.4 and R.sup.5, which may be the same or different, is a hydrogen atom, halogen atom, lower alkyl group or lower alkoxy group, R.sup.6 is a hydrogen atom, halogen atom, hydroxy group, lower alkyl group or amino group, R.sup.7 is a hydrogen atom or halogen atom, A is a nitrogen atom or --CX.dbd. wherein X is a halogen atom, lower alkyl group or lower alkoxy group, and Z is a halogen atom or a saturated cyclic amino group which may have a substitutent, or a salt thereof.
- 8. An antibacterial agent comprising a pyridonecarboxylic acid derivative or a salt thereof as set forth in claim 7 as an active ingredient and a pharmaceutically acceptable carrier therefor.
- 9. A method of treating a person infected with bacteria by administering an effective amount of the compound of claim 7 to a person in need thereof.
- 10. A method of treating an animal infected with bacteria by administering an effective amount of the compound of claim 7 to an animal in need thereof.
- 11. A method of treating a person infected with a virus by administering an effective amount of the compound of claim 7 to a person in need thereof.
- 12. A method of treating an animal infected with a virus by administering an effective amount of the compound of claim 7.
Priority Claims (2)
Number |
Date |
Country |
Kind |
6-255046 |
Oct 1994 |
JPX |
|
7-012673 |
Jan 1995 |
JPX |
|
Parent Case Info
This application is a 371 of PCT/JP95/02156 filed Oct. 20, 1995.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
102e Date |
371c Date |
PCT/JP95/02156 |
10/20/1995 |
|
|
7/8/1997 |
7/8/1997 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO96/12704 |
5/2/1996 |
|
|
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4146719 |
Irikura |
Mar 1979 |
|
Foreign Referenced Citations (5)
Number |
Date |
Country |
53-141286 |
Dec 1978 |
JPX |
55-31042 |
Mar 1980 |
JPX |
57-46986 |
Mar 1982 |
JPX |
60-228479 |
Nov 1985 |
JPX |
62-135458 |
Jun 1987 |
JPX |