Claims
- 1. A compound of the Formula (I) ##STR7## wherein R is a C.sub.1 to C.sub.12 alkyl group substituted by C.sub.1 to C.sub.4 alkoxycarbonyl, a C.sub.3 to C.sub.9 cycloalkyl group, an adamantyl group, or a phenyl group substituted by halogen, C.sub.1 to C.sub.4 alkyl, C.sub.2 to C.sub.5 alkoxy, hydroxy, trifluoromethyl, cyano, C.sub.1 to C.sub.4 alkoxycarbonyl, carboxy or methylenedioxy;
- R.sup.1 is hydrogen or a C.sub.1 to C.sub.4 alkyl group; or R and R.sup.1 together form a --(CH.sub.2).sub.n -- chain, wherein n is 4,5 or 6;
- R.sup.2 is hydrogen, a C.sub.1 to C.sub.4 alkyl group or halogen; and
- R.sup.3 is hydrogen or a C.sub.1 to C.sub.4 alkyl group;
- or a pharmaceutically acceptable acid addition salt thereof.
- 2. A compound of the Formula (IA) ##STR8## wherein R is C.sub.3 to C.sub.9 cycloalkyl; and
- R.sup.2 is C.sub.1 to C.sub.4 alkyl; or a pharmaceutically acceptable acid addition salt thereof.
- 3. The compound of the Formula (I) defined in claim 2 which is N-cyclopentyl-6-methyl-4-oxo-4H-pyrido(1,2-a)pyrimidine-3-carboxamide or a pharmaceutically acceptable acid addition salt thereof.
- 4. The compound of the Formula (I) defined in claim 2 which is N-cyclopentyl-9-methyl-4-oxo-4H-pyrido(1,2-a)-pyrimidine-3-carboxamide or a pharmaceutically acceptable acid addition salt thereof.
- 5. The compound of the Formula (I) defined in claim 2 wherein R is a C.sub.3 to C.sub.9 cycloalkyl group or a pharmaceutically acceptable acid addition salt thereof.
- 6. The compound of Formula (I) defined in claim 2 wherein R is a cyclopentyl group or a pharmaceutically acceptable acid addition salt thereof.
- 7. An anti-ulcer pharmaceutical composition which comprises as active ingredient a therapeutically effective amount of the compound of the Formula (I) defined in claim 1 or a pharmaceutically acceptable acid addition salt thereof in admixture with a pharmaceutically acceptable inert carrier.
Parent Case Info
This is a continuation of co-pending application Ser. No. 07/307,665 filed on 6 Feb. 1989, now U.S. Pat. No. 5,158,951.
US Referenced Citations (8)
Non-Patent Literature Citations (1)
Entry |
Magyar Kemikusol Papja 31, pp. 281-292 (1976) and Partial English Translation. |
Continuations (1)
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Number |
Date |
Country |
Parent |
307665 |
Feb 1989 |
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