Claims
- 1. A compound of the formula: ##STR26## where X is ##STR27## S, or SO.sub.2 ; the R's are the same or different and are H, CH.sub.3 ; or OCH.sub.3 ; and one of them can be C.sub.2 -C.sub.9 alkyl, phenyl, C.sub.7 -C.sub.10 phenylalkyl, furyl, thienyl, pyridyl, phenyl or C.sub.7 -C.sub.10 phenylalkyl substituted on adjacent ring carbon atoms with methylenedioxy, or phenyl or C.sub.7 -C.sub.10 phenylalkyl substituted on the ring with 1, 2 or 3 substituents individually selected from methoxy, ethoxy, bromine, chlorine, fluorine, trifluoromethyl and C.sub.1 -C.sub.4 alkyl;
- R.sub.1 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.5 alkenyl, C.sub.3 -C.sub.5 alkynyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.2 -C.sub.4 alkoxycarbonyl, trifluoroacetyl or substituted C.sub.1 -C.sub.4 alkyl where the substituent is C.sub.3 -C.sub.6 cycloalkyl, phenyl, phenyl substituted on adjacent carbon atoms with methylenedioxy, or phenyl substituted with 1, 2 or 3 substituents individually selected from methoxy, ethoxy, bromine, chlorine, fluorine, and trifluoromethyl; and
- Z is H, Cl, or CH.sub.3 ;
- and their pharmaceutically suitable salts.
- 2. Compound of claim 1: 8-cyclopropyl-1,2,7,8,9,10-hexahydropyrido[3',4':4,5]pyrrolo[1,2,3-de][1,4]benzothiazine and its pharmaceutically suitable salts.
CROSS REFERENCE TO RELATED APPLICATION
This is a Ser. No. 916,846, filed June 16, 1978, now U.S. Pat. No. 4,183,936 which is a division of Application Ser. No. 755,121, filed Dec. 28, 1976, now U.S. Pat. No. 4,115,577; which in turn is a division of Application Ser. No. 586,746, filed June 13, 1975, now U.S. Pat. No. 4,013,652; which in turn is a division of Application Ser. No. 357,528, filed May 7, 1973, now U.S. Pat. No. 3,914,421; which is a continuation-in-part of Application Ser. No. 263,766, filed June 19, 1972, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4013652 |
Rajagopalan |
Mar 1977 |
|
4115577 |
Rajagopalan |
Sep 1978 |
|
Divisions (4)
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Number |
Date |
Country |
Parent |
916846 |
Jun 1978 |
|
Parent |
755121 |
Dec 1976 |
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Parent |
586746 |
Jun 1975 |
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Parent |
357528 |
May 1973 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
263766 |
Jun 1972 |
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