Claims
- 1. A compound of the formula ##STR4## and the pharmaceutically acceptable salts thereof wherein Y is a member selected from the group consisting of uracil, cytosine, and thymine; R.sup.1 is selected from hydrogen and alkyl of 1 to 4 carbon atoms; R.sup.2 is selected from hydrogen, alkyl of 1 to 4 carbon atoms, and --CH.sub.2 OH; and Z is >CH.sub.2 or >O.
- 2. A compound according to claim 1 wherein Y is a pyrimidin-1-yl group.
- 3. A compound according to claim 1 wherein Y is ##STR5##
- 4. A compound according to claim 1 wherein Y is ##STR6##
- 5. A pharmaceutical composition comprising an effective amount of a compound of claim 1 and a pharmaceutically acceptable carrier.
- 6. A method of treating virus infections selected from the group consisting of the herpes family and RNA viruses consisting of influenza and retroviruses in mammals comprising administering to a mammal in need of such treatment an effective amount of a compound of claim 1.
- 7. A compound of the formula ##STR7## wherein Q is H or ##STR8## W is H, --N.dbd.O, ##STR9## or --NH.sub.2 ; R.sup.1 is hydrogen or alkyl of 1 to 4 carbon atoms; and R.sup.2 is hydrogen, alkyl of 1 to 4 carbon atoms or --CH.sub.2 OH.
- 8. A compound according to claim 7 wherein Q is H.
Parent Case Info
This is a continuation of application Ser. No. 889,014, filed July 24, 1986, now abandoned, which application is a continuation-in-part of U.S. patent application Ser. No. 598,612, filed Apr. 10, 1984, U.S. Pat. No. 4,617,304, issued Oct. 14, 1986.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4617304 |
Ashton et al. |
Oct 1986 |
|
Non-Patent Literature Citations (2)
Entry |
Khare et al., Proc. Soc. Exp. Biol. & Med., 140, pp. 880-884 (1972). |
Rada & Doskocil, Pharmacol. & Therap., 9, pp. 171-217 (1980). |
Continuations (1)
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Number |
Date |
Country |
Parent |
889014 |
Jul 1986 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
598612 |
Apr 1984 |
|