Claims
- 1. N-�4-(4-Phenylpiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl!-N-methyl-3-isopropoxyphenyl-acetamide or a pharmaceutically acceptable salt thereof.
- 2. N-�4-(4-Phenylpiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl!-N-methyl-3-isopropoxyphenyl-acetamide hydrochloride.
- 3. N-�4-(4-phenylpiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl!-N-methyl-.alpha.-hydroxy-(3-isopropoxyphenyl)acetamide or a pharmaceutically acceptable salt thereof.
Priority Claims (2)
Number |
Date |
Country |
Kind |
92 02542 |
Mar 1992 |
FRX |
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92 12941 |
Oct 1992 |
FRX |
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Parent Case Info
This application is a divisional of application Ser. No. 08/345,341, filed Nov. 21, 1994, U.S. Pat. No. 5,674,881, which is a continuation of Ser. No. 08/026,154, filed Mar. 3, 1993 now abandoned.
US Referenced Citations (5)
Foreign Referenced Citations (4)
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0 288 352 |
Oct 1988 |
EPX |
0 474 561 |
Mar 1991 |
EPX |
0 428 434 |
May 1991 |
EPX |
0 515 240 |
Nov 1992 |
EPX |
Non-Patent Literature Citations (4)
Entry |
"Synthesis and Local Anesthetic Activity of N-Diethylaminoacetly Derivatives of Napthlyalkylamines", J. Medical Chem. 14(9):896-897 (1970). |
"Central Nervous System Activity of Ethyl 1-Naphthylalkylcarbamates", J. Medicinal Chem. 13(4):747-748 (1970). |
"Effects on the Isolated Human Bronchus of 48968, a Potent and Selective Nonpeptide Antagonist of the Neurokinin A (NK.sub.2) Receptors", Chem. Abstracts 118:32786. (1992). |
Burger, "Medicinal Chemistry", Interscience Publisher, p. 42 (1960). |
Divisions (1)
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Number |
Date |
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Parent |
345341 |
Nov 1994 |
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Continuations (1)
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Date |
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Parent |
26154 |
Mar 1993 |
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