Claims
- 1. A method of treating a subject for hyperactive syndrome which comprises administering to the subject an amount of R(+)-N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof effective to treat the subject.
- 2. The method of claim 1, wherein the R(+)-N-propargyl-1-aminoindan or pharmaceutically acceptable salt thereof is administered orally or rectally.
- 3. The method of claim 2, wherein the amount administered is from about 0.1 milligram to about 100 milligrams.
- 4. The method of claim 3, wherein the amount administered is from about 1 milligram to about 10 milligrams.
- 5. The method of claim 1, wherein the R(+)-N-propargyl-1-aminoindan or pharmaceutically acceptable salt thereof is administered parenterally.
- 6. The method of claim 5, wherein the amount administered is from about 0.1 milligram to about 100 milligrams per milliliter.
- 7. The method of claim 6, wherein the amount administered is from about 1 milligram to about 10 milligrams per milliliter.
- 8. A method of treating a subject afflicted with an attention deficit disorder which comprises administering to the subject an amount of R(+)-N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof effective to treat the attention deficit disorder in the subject.
- 9. The method of claim 8, wherein the pharmaceutically acceptable salt is selected from the group consisting of the mesylate salt of R(+)-N-propargyl-1-aminoindan, the esylate salt of R(+)-N-propargyl-1-aminoindan, and the sulfate salt of R(+)-N-propargyl-1-aminoindan.
Priority Claims (1)
Number |
Date |
Country |
Kind |
92952 |
Jan 1990 |
ILX |
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Parent Case Info
This is a divisional of U.S. Ser. No. 08/411,398, filed Mar. 28, 1995, which is a continuation of U.S. Ser. No. 08/139,517, filed Oct. 18, 1993 (now abandoned), which is a continuation-in-part of U.S. Ser. No. 08/063,455, filed May 18, 1993 (now abandoned), which is a continuation of U.S. Ser. No. 07/632,184, filed Dec. 21, 1990 (now abandoned), claiming priority of Israeli application No. 92,952, filed Jan. 3, 1990, the contents of which are hereby incorporated by reference.
US Referenced Citations (4)
Foreign Referenced Citations (1)
Number |
Date |
Country |
1003686 |
Sep 1965 |
GBX |
Non-Patent Literature Citations (10)
Entry |
Brit. J. Pharm. 85:541-6 (1985). |
The Merck Index, Tenth Ed. pp. 149, 248-249 (1983). |
Finberg and Youdim, British J. Pharmac. (Jun. 1985) 85(2):541-546. |
Kabins and Gershon, Dementia (1990) 1:323-348. |
The Merck Index (Tenth ed. 1983) pp. 149, 248-249. |
The Parkinson Study Group, New England J. Med. (1989) 321(20):1364-1371. |
The Parkinson Study Group, New England J. Med. (Jan. 21, 1993) 328(3):176-183. |
Riederer and Youdim, J. Neurochem. (1986) 46(5):1359-1365. |
Tekes, et al., Pol. J. Pharmacol. Pharm. (1988) 40:653-658. |
Youdim, et al., in Handbook of Experimental Pharmacology vol. 90/I (1988) Chapter 3, Trendelenburg and Weiner, eds. |
Divisions (1)
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Number |
Date |
Country |
Parent |
411398 |
Mar 1995 |
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Continuations (2)
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Number |
Date |
Country |
Parent |
139517 |
Oct 1993 |
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Parent |
632184 |
Dec 1990 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
63455 |
May 1993 |
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