Claims
- 1. A radioactive composition for the scintigraphic imaging of the hepatobiliary system, the composition comprising a complex of .sup.99m Tc with a dicarboxylic acid of the formula: ##STR4## in which R.sup.1 and R.sup.2 are each an ethyl or an isopropyl group, and R.sup.3 is hydrogen, or each of R.sup.1, R.sup.2 and R.sup.3 are a methyl group, or one of its water-soluble salts, in sterile, aqueous solution.
- 2. The composition of claim 1 wherein R.sup.1, R.sup.2 and R.sup.3 are each a methyl group.
- 3. The composition of claim 1 further comprising tin chloride as a component of the complex.
- 4. The composition of claim 1 wherein the dicarboxylic acid is present as its sodium salt.
- 5. The composition of claim 1 further comprising a tin salt as a component of the complex.
- 6. A method of preparing the composition of claim 1, the method comprising allowing the dicarboxylic acid defined in claim 1, or a water-soluble salt thereof, to react under sterile conditions with an aqueous solution containing .sup.99m Tc ions.
- 7. The method of claim 8 wherein the dicarboxylic acid or the water-soluble salt thereof is allowed to react with an aqueous .sup.99m Tc-pertechnetate solution in the presence of a tin(II) salt.
- 8. The method of claim 7 wherein the .sup.99m Tc-pertechnetate solution is a solution of sodium .sup.99m Tc-pertechnetate and the tin(II) salt is tin(II) chloride.
- 9. A method for imaging the hepatobiliary system comprising injecting the composition of claim 1 and subsequently scanning the body for radioactivity.
Priority Claims (1)
Number |
Date |
Country |
Kind |
6793/76 |
May 1976 |
CHX |
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Parent Case Info
This is a continuation of application Ser. No. 797,664 filed May 17, 1977, abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3981980 |
Baker et al. |
Sep 1976 |
|
4017596 |
Loberg et al. |
Apr 1977 |
|
4027005 |
Adler et al. |
May 1977 |
|
Non-Patent Literature Citations (1)
Entry |
Wistow et al., J. Nuc. Med., vol. 17, No. 6, 1976, p. 545. |
Continuations (1)
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Number |
Date |
Country |
Parent |
797664 |
May 1977 |
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