RADIOIODINATED CONJUGATES FOR THERAPY AND DIAGNOSIS

Information

  • Research Project
  • 3614215
  • ApplicationId
    3614215
  • Core Project Number
    N44CM067759
  • Full Project Number
    N44CM067759-001
  • Serial Number
    67759
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/30/1986 - 38 years ago
  • Project End Date
    9/29/1988 - 36 years ago
  • Program Officer Name
  • Budget Start Date
    6/30/1987 - 37 years ago
  • Budget End Date
    9/29/1988 - 36 years ago
  • Fiscal Year
    1987
  • Support Year
  • Suffix
  • Award Notice Date
    -
Organizations

RADIOIODINATED CONJUGATES FOR THERAPY AND DIAGNOSIS

The contractor shall optimize the radioiodination reactions and test several difference radioiodinated conjugates for in vitro and in vivo stability. A comparison of a conventional (directly) radioiodinated antibody with the same antibody labeled using the radioiodinated conjugates, will be carried out. Studies using an iodine-131 labeled antibody will be conducted (in nude rats) to measure tissue dosimetry. The untimate goal of the study is to identify n antibody and a radioiodine conjugate that can become a commercial cancer therapy agent.

IC Name
DIVISION OF CANCER TREATMENT
  • Activity
    N44
  • Administering IC
    CM
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    395
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
  • Study Section Name
  • Organization Name
    NEORX CORPORATION
  • Organization Department
  • Organization DUNS
  • Organization City
    SEATTLE
  • Organization State
    WA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    98119
  • Organization District
    UNITED STATES