Patent Application
20090211917
The present invention relates to producing Tl-201; more particularly, relates to quickly filtering out a high-purity Tl-201 liquid.
Tl-201 thallous chloride (201TlCl2) can be absorbed by heart muscle to be gathered at the heart muscle. Therefore, Tl-201 can be used in a myocardial image for diagnosing heart disease; and can be applied in other medical diagnoses, like a tumor image. Hence, Tl-201 is the most commonly used radioisotope in division of nuclear medicine.
To produce a Tl-201, as revealed in “Production of Tl-201 and Pb203 via Proton Induced Nuclear Reaction on Natural Thallium”, by Qaim S. M., Weinreich R. and Ollig H., International Journal of Applied Radiation and Isotopes, 30 (1979) pp. 85-95, Tl-201 is directly washed out. But the Tl-201 directly washed out quite often contains impurities so that its purity is not good. Hence, the prior art does not fulfill users' requests on actual use.
The main purpose of the present invention is to form a Tl-203 solid target material through electroplating, irradiate the Tl-203 solid target material with a proton beam, dissolve the Tl-203 solid target material to process through a first chemical separation and a second chemical separation, and quickly filter out a high-purity Tl-201 liquid.
To achieve the above purpose, the present invention is a radioisotope Tl-201 production process, where a Tl-203 solid target material is obtained from a plated target material of Tl-203 through electroplating; the Tl-203 solid target material is irradiated with a proton beam by using a cyclotron; the Tl-203 solid target material is dissolved with a strong acid liquid to obtain a Pb-201 solution and a Tl-203 solution; ammonia and water are added for a precipitation to separate a Tl-201 liquid and a Pb-201 liquid out; hydrochloric acid is added for a first ion exchange with a resin while impurities are filtered out; the Pb-201 liquid is taken out to be decayed into a Tl-201 liquid; and a hydrochloric acid (HCl) having sulfur dioxide (SO2) is added to the Tl-201 liquid to obtain a Tl-201 liquid having a high purity through a second ion exchange by using a resin. Accordingly, a novel radioisotope Tl-201 production process is obtained.
The present invention will be better understood from the following detailed description of the preferred embodiment according to the present invention, taken in con junction with the accompanying drawings, in which
The following description of the preferred embodiment is provided to understand the features and the structures of the present invention.
Please refer to
Please refer to
(a) Electroplating 1: A Tl-203 solid target material 12 is obtained from a plated target material 11 of Tl-203 through electroplating.
(b) Irradiating 2: The Tl-203 solid target material 12 is irradiated with a proton beam by using a cyclotron 21, where an irradiation energy of the cyclotron 21 is located between fifteen mega electron volts (MeV) and forty MeV.
(c) Processing a first chemical separation: The first chemical separation 3 comprises the following steps:
(d) Decaying 4: The Pb-201 liquid is taken out to be decayed into a Tl-201 liquid 41.
(e) Processing a second chemical separation: And a second chemical separation 5 is processed, which is a second ion exchange 51.
Thus, a novel radioisotope Tl-201 production process is obtained.
To sum up, the present invention is a radioisotope Tl-201 production process, where a Tl-203 solid target material is formed through an electroplating; the Tl-203 solid target material is irradiated with a proton beam; the Tl-203 solid target material is dissolved to be processed through a first chemical separation and a second chemical separation; and a Tl-201 liquid is quickly filtered out, which has a high purity.
The preferred embodiment herein disclosed is not intended to unnecessarily limit the scope of the invention. Therefore, simple modifications or variations belonging to the equivalent of the scope of the claims and the instructions disclosed herein for a patent are all within the scope of the present invention.
