Patent Application
20200150139
The present invention relates to a receptacle terminal. Further, the present invention relates to a method of providing a receptacle. Furthermore, the present invention relates to a computer program product. Additionally, the present invention relates to a computer-readable data carrier.
A wide variety of automated laboratory systems are known in the art and widely used in hospitals, clinics, and research laboratories. A laboratory automation system typically comprises a number of stations, in which samples, for example blood, saliva, swap, and other target substances are processed. The device complex may comprise a plurality of separate devices such as a sample analyzer, a conveyor system, a receptacle terminal, and a sample storage, for instance. In automated systems handling receptacles with target substances contained in a sample, typically so called sample tubes, test tubes, cuvettes, sample containers, sample vessels, or other sample receptacles, particularly elongate receptacles, are used for temporarily storing the target substance. The sample tubes, test tubes, cuvettes or other sample receptacles, in the following only referred to as “receptacles”, can be e.g. placed in so called sample receptacle holders. Each receptacle holder can support one receptacle upright. A plurality of sample receptacles may be supported by a so called rack, carrier, magazine, test tube rack, sample tube rack, tube tray, sample tube keeper, sample tube carrier, or the like. In the following said device is only referred to as “receptacle rack”.
In an automated laboratory system or a part thereof, there is a desire to have manually access to at least one specific sample receptacle supported by a specific receptacle holder or a specific receptacle rack. Thus, a specific receptacle can be manipulated, for instance. Additionally, a specific receptacle may be manually inserted into the automated laboratory system or removed from the system.
For example, document U.S. Pat. No. 8,691,149 B2 discloses a system for automatically loading an immunoassay analyzer. A front panel of a magnetic particle processor comprises a rotatable upper portion, which has a closed position and an open position. The rotatable upper portion is attached to a top panel or cover by a first hinge and a second hinge. The rotatable upper portion also has a handle to enable a user to manually open and close the rotatable upper portion. The rotatable upper portion has an aperture formed at the center of an edge of the rotatable upper portion. The aperture must be of sufficient size to enable a supporting rail to pass through it. The supporting rail supports a supporting tray, which is capable of supporting at least one micro-well plate. The supporting rail is fixed at the distal end thereof and is free at the proximal end thereof. The supporting rail is sufficiently rigid and sufficiently strong to support both the supporting tray and the equipment, that are required to move the supporting tray into and out of the magnetic particle processor. The supporting rail allows the micro-well plate(s) to be manipulated at some distance apart from the interior of the magnetic particle processor. The supporting rail must be of a sufficient length to enable the supporting tray to be extended a sufficient distance to be clear of a front panel. The supporting tray is capable of being driven along the supporting rail away from the magnetic particle processor and towards the magnetic particle processor. A stepper motor, an encoder, a drive gear, a threaded lead screw, and a threaded nut can be used to control the motion of the supporting tray for the micro-well plate(s). The system is designed to enable the automatic insertion and removal of reaction vessels into and out of a magnetic particle processor.
In view of the foregoing, it would be beneficial to provide a receptacle terminal, e.g. for an automated laboratory system or a part thereof, which receptacle terminal is capable of providing a user manual access to at least one specific sample receptacle. The receptacle terminal should be capable of being manufactured in industrial scale.
The invention is defined by the features of the independent claims. Some specific embodiments are defined in the dependent claims.
According to a first aspect of the present invention, there is provided a receptacle terminal comprising a housing, and a first transporting unit which is configured to transport at least a first receptacle rack, which is arranged on a movable platform, within the housing from a first position to a second position, and wherein the first receptacle rack is at the second position within the housing and manually accessible by a user through a first opening in the housing.
Various embodiments of the first aspect may comprise at least one feature from the following bulleted list:
According to a second aspect of the present invention, there is provided a method comprising selecting a specific receptacle, removing the receptacle from a second receptacle rack and inserting the receptacle into a first receptacle rack by means of a second transporting unit, transporting the first receptacle rack, which is arranged on a movable platform, within a housing of a receptacle terminal from a first position, wherein the first receptacle rack is accessible by the second transporting unit, to a second position by means of a first transporting unit, wherein the first receptacle rack is at the second position within the housing and manually accessible by a user through a first opening in a housing.
According to an embodiment, the method further comprises feeding the receptacle terminal with a receptacle rack by the third transporting unit or removing a receptacle rack from the receptacle terminal by the third transporting unit. According to another embodiment, the method yet further comprises transporting a receptacle rack to or from a slot of the platform through a second opening in the housing by the third transporting unit.
According to a third aspect of the present invention, there is provided a computer program product comprising instructions which, when the program is executed by a computer, cause the computer to carry out the steps receiving instructions from a user regarding selection of a specific receptacle, causing a second transporting unit to remove the receptacle from a second receptacle rack and to insert the receptacle into a first receptacle rack, causing a first transporting unit to transport the first receptacle rack, which is arranged on a movable platform, within a housing of a receptacle terminal from a first position, wherein the first receptacle rack is accessible by the second transporting unit, to a second position, wherein the first receptacle rack is at the second position within the housing and manually accessible by a user through a first opening in the housing.
According to a fourth aspect of the present invention, there is provided a computer-readable data carrier having stored thereon the computer program product of claim 24.
Considerable advantages are obtained by certain embodiments of the invention. A receptacle terminal and a method of providing a receptacle are provided according to certain embodiments of the present invention. The receptacle terminal, e.g. for an automated laboratory system or a part thereof, is capable of providing a user manual access to at least one specific sample receptacle. The specific sample receptacle, for example a sample tube, may be delivered to a user access area by a first transporting unit upon request by a user. Of course, the receptacle terminal is also capable of receiving a receptacle, which has been manually inserted by a user, and transferring it to a receptacle rack. Thus, a user can request a specific receptacle to be delivered and re-insert the receptacle at a later stage, for instance. The delivery and re-insertion of the receptacle can take place quickly, because the receptacle is transported along a relatively short distance by the first transporting unit via a linear guide.
Further, the user access area is located within the housing of the receptacle terminal. Thus, a user cannot collide with parts of the receptacle terminal protruding from the housing of the receptacle terminal, for example with a supporting rail supporting a supporting tray or a drawer. In other words, safety of a user and simultaneously also safety of receptacles contained in the receptacle terminal and safety of the receptacle terminal can be improved.
Furthermore, a user cannot come physically into contact with a robot handling the receptacles due to providing at least one specific receptacle from a robot access area to a separate user access area, thus further improving safety. According to certain embodiments, the second transporting unit may be capable of operating as the first receptacle rack is positioned at the second position, i.e. the user access area.
Additionally, positioning of receptacle racks and therefore also of the receptacles can be performed very precisely on the movable platform. The platform can be further moved very precisely by means of the first transporting unit. Consequently, tolerances required for handling receptacles with the second transporting unit, for example a mechanical gripper, can be easily fulfilled.
According to certain embodiments, the receptacle terminal can be connected to a sample storage. Receptacle racks can be fed into the receptacle terminal through a second opening in the housing by means of a third transporting unit. Of course, receptacle racks can also be removed from the receptacle terminal and be fed into the sample storage.
Further, receptacles may be disregarded by transporting the receptacles with the second transporting unit to a disposal port. Additionally, the receptacle terminal may be connected to a device complex. Receptacles contained in the receptacle terminal can then be delivered by the second transporting unit to other systems of the device complex comprising the receptacle terminal.
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Therefore, a user cannot collide with parts of the receptacle terminal protruding from the housing of the receptacle terminal. Safety of a user and simultaneously also safety of receptacles contained in the receptacle terminal and safety of the receptacle terminal can be thus improved.
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In the shown embodiment, handling of receptacles supported by the second receptacle rack 19 being farthest away from the hatch 12 can be performed by the second transporting unit 10, even if the first receptacle rack 4 being located closest to the hatch 12 is only accessible by the user. In other words, the receptacle terminal 1 provides a user access area and a robot access area. A user can have manually access to the first receptacle rack 4 and simultaneously the second transporting unit 10 can handle receptacles supported by the second receptacle rack 19 according to the shown embodiment. According to other embodiments, the second transporting unit 10 is configured to interrupt operation as the first receptacle rack 4 is positioned at the second position 6.
The first transporting unit 3 is configured to linearly guide at least a first receptacle rack 4 from the first position, in which the first receptacle rack 4 is located in the robot access area, to the second position, in which the first receptacle rack 4 is located in the user access area. Of course, the first transporting unit 3 is also configured to linearly guide at least the first receptacle rack 4 from the second position to the first position, i.e. in an opposite direction. Typically, the first transporting unit 3 is configured to move the platform 9 along a linear guide 8, and thus also the first receptacle rack 4 supported by the movable platform 9.
The second transporting unit 10 may be, for example, a handling robot such as a mechanical gripper which is capable of moving a receptacle in two or three dimensions. A user cannot come physically into contact with the second transporting unit 10 handling the receptacles within the housing 2. The second transporting unit 10 may be configured to remove a single receptacle, e.g. a sample tube, test tube, cuvette, sample container, sample vessel, or other sample receptacle, particularly an elongate receptacle, from the second receptacle rack 19 positioned in the robot access area and to subsequently transport the respective receptacle to a disposal port 13 comprising at least one disposal hole, for instance. The second transporting unit 10 may be also configured to, for example, remove a respective receptacle from one receptacle rack and to subsequently insert the receptacle into another receptacle rack. The other receptacle rack may be provided in the robot access area by moving the platform 9 along the linear guide 8 by means of the first transporting unit 3. Further, the second transporting unit 10 may also be, for example, configured to remove a receptacle from a receptacle rack and to transport the respective receptacle to another system of a device complex (not shown) via a delivery port 22. The other system of the device complex may be, for example a conveyor system, which is configured to transport a series of further receptacle holders or further receptacle racks.
Furthermore, the receptacle terminal 1 can optionally comprise a third transporting unit (not shown) which is configured to transport at least one receptacle rack or a series of receptacle racks to or from respective slots of the platform 9 through a further second opening 21 in the housing 2, for example to or from a receptacle storage (not shown). The second opening functions as an inlet/outlet. The platform 9 according to the shown embodiment comprises five slots for receptacle racks in total. Thus, it is possible to feed the receptacle terminal 1 with receptacle racks as well as to remove receptacle racks from the receptacle terminal 1 through the second opening 21 by means of the third transporting unit.
The first transporting unit 3 is further configured to transport a plurality of receptacle holders 11 within the housing 2 from the first position 5, i.e. the user access area, to the second position 6, in which the first receptacle rack is located in the robot access area. The receptacle holders 11 are at the second position 6 manually accessible by the user through the first opening in the housing 2. When the receptacle holders 11 have been transported by the first transporting unit 3 to their first position, receptacles can be removed from the respective receptacle holders 11 and inserted into the receptacle holders 11 by the second transporting unit 10. The receptacle holders 11 may be an integral part of the platform 9 or arranged on the platform 9.
The housing 2 of the receptacle terminal 1 further includes a hatch 12 which is configured cover the first opening, and thus also the user access area. Contamination of the receptacle terminal 1 as well as of the receptacles contained in the receptacle terminal can be reduced due to the hatch 12.
Additionally, the receptacle terminal 1 according to certain embodiments comprises a computing device 14. It is e.g. possible to cause the second transporting device (10) to select a specific receptacle, which is located in one of the receptacle racks, and to insert the respective receptacle into the first receptacle rack 4 being located closest to the hatch 12 or into one of the receptacle holders 11 and to subsequently cause the first transporting unit 3 to transport the receptacle to the second position, i.e. to the user access area, by instructing the computing device 14. Thus, the user can select a specific receptacle to be delivered to the user access area of the receptacle terminal 1. The user may then manually manipulate the respective receptacle, for instance. Of course, the user may also insert a specific receptacle into one of the receptacle holders 11 or into the first receptacle rack 4 being located closest to the hatch 12 and instruct the computing device 14 to cause the first transporting unit 3 and the second transporting unit 10 to transport the respective receptacle to any one of the receptacle racks. In other words, by means of the receptacle terminal 1 it is possible to feed an automated device complex comprising the receptacle terminal 1 with a receptacle or to remove a receptacle from the automated device complex, for instance.
Additionally, the computing device 14 may be instructed by the user to cause transporting of a receptacle to the disposal section 13. For example, a receptacle may be manually inserted into one of the receptacle holders 11 or into the receptacle rack 4 being located closest to the hatch 12 and then transported by the first transporting unit 3 to the first position, i.e. the robot access area. Then, the second transporting unit 10 can remove the respective receptacle from the receptacle holder 11 or the first receptacle rack 4, transport the receptacle to the disposal port 13, and drop the receptacle into one of the disposal holes of the disposal port 13. Subsequently, the receptacle is guided to a disposal container (not shown).
Each receptacle may be provided with a barcode. The receptacle terminal 1 may further comprise a barcode reader (not shown) connected to the computing device 14. A specific receptacle can thus be identified and may be transported by means of the first transporting device 3 and the second transporting device 10, for example to a disposal port 13, another system of a device complex, a receptacle storage, the first receptacle rack, another receptacle rack, the user access area, or the robot access area.
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According to certain embodiments, the second transporting unit 10 is capable of handling receptacles located in the robot access area as the first receptacle rack 4 is located at the first position 6. According to certain other embodiments, interruption of handling of receptacles located in the robot access area by the second transporting unit 10 takes place as the first receptacle rack 4 is located at the first position 6.
In
Receptacles supported by a second receptacle rack 19 and receptacles supported by a third receptacle rack 20 are located in the robot access area 17 and thus accessible by the second transporting unit 10. Typically, at least two receptacle racks can be located in the robot access area 17. The first receptacle rack 4 has to be transported by the first transporting unit to the robot access area 17 in order to have access to the first receptacle rack 4 or one of the receptacle holders 11 by means of the second transporting unit 10. Also the receptacle racks arranged between the third receptacle rack 20 and the first receptacle rack 4 are neither manually accessible by a user nor by the second transporting unit 10.
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The first receptacle rack 4 as well as the receptacle holders 11 are not manually accessible by a user. The first receptacle rack 4 as well as the receptacle holders 11 are accessible by a second transporting unit 10. In other words, the first receptacle rack 4 has been transported to the first position 5, i.e. to the robot access area. The second transporting unit 10 is capable of operating as the at least one receptacle rack 4 is positioned at the second position 6. For example, a receptacle supported by the first receptacle rack 4 or one of the receptacle holders 11 may be removed from the first receptacle rack 4 by the second transporting unit 10 and then transported to a disposal port (not shown).
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Additionally, the platform 9 is coupled to the belt 23. Thus, it is possible to move the platform 9 and at least a first receptacle rack 4, which is arranged on the movable platform 9, along the linear guides 8 from a first position, in which the first receptacle rack 4 is accessible by a second transporting unit 10, to a second position, in which the first receptacle rack 4 is accessible by a user. Of course, it is also possible to move the platform 9 and at least the first receptacle rack 4 along the linear guides 8 from the second position to the first position. Consequently, it is possible to deliver at least one specific receptacle 18 from a robot access area to a user access area and in the opposite direction.
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Instead of inserting the receptacle into the first receptacle rack 4, the receptacle may also be inserted into a receptacle holder 11 by means of the second transporting unit 10. The method then further comprises transporting the receptacle holder 11, which is arranged on a movable platform 9, within a housing 2 of a receptacle terminal 1 from a first position 5, wherein the receptacle holder 11 is accessible by the second transporting unit 10, to a second position 6 by means of a first transporting unit 3, wherein the receptacle holder 11 is at the second position 6 within the housing 2 and manually accessible by a user through a first opening 7 in a housing 2.
It is to be understood that the embodiments of the invention disclosed are not limited to the particular structures, process steps, or materials disclosed herein, but are extended to equivalents thereof as would be recognized by those ordinarily skilled in the relevant arts. It should also be understood that terminology employed herein is used for the purpose of describing particular embodiments only and is not intended to be limiting.
Reference throughout this specification to one embodiment or an embodiment means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present invention. Thus, appearances of the phrases “in one embodiment” or “in an embodiment” in various places throughout this specification are not necessarily all referring to the same embodiment. Where reference is made to a numerical value using a term such as, for example, about or substantially, the exact numerical value is also disclosed.
As used herein, a plurality of items, structural elements, compositional elements, and/or materials may be presented in a common list for convenience. However, these lists should be construed as though each member of the list is individually identified as a separate and unique member. Thus, no individual member of such list should be construed as a de facto equivalent of any other member of the same list solely based on their presentation in a common group without indications to the contrary. In addition, various embodiments and example of the present invention may be referred to herein along with alternatives for the various components thereof. It is understood that such embodiments, examples, and alternatives are not to be construed as de facto equivalents of one another, but are to be considered as separate and autonomous representations of the present invention.
Furthermore, the described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments. In the following description, numerous specific details are provided, such as examples of lengths, widths, shapes, etc., to provide a thorough understanding of embodiments of the invention. One skilled in the relevant art will recognize, however, that the invention can be practiced without one or more of the specific details, or with other methods, components, materials, etc. In other instances, well-known structures, materials, or operations are not shown or described in detail to avoid obscuring aspects of the invention.
While the forgoing examples are illustrative of the principles of the present invention in one or more particular applications, it will be apparent to those of ordinary skill in the art that numerous modifications in form, usage and details of implementation can be made without the exercise of inventive faculty, and without departing from the principles and concepts of the invention. Accordingly, it is not intended that the invention be limited, except as by the claims set forth below.
The verbs “to comprise” and “to include” are used in this document as open limitations that neither exclude nor require the existence of also un-recited features. The features recited in depending claims are mutually freely combinable unless otherwise explicitly stated. Furthermore, it is to be understood that the use of “a” or “an”, that is, a singular form, throughout this document does not exclude a plurality.
At least some embodiments of the present invention find industrial application in automated laboratory systems.
U.S. Pat. No. 8,691,149 B2
| Number | Date | Country | Kind |
|---|---|---|---|
| 20175432 | May 2017 | FI | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/FI2018/050307 | 4/26/2018 | WO | 00 |
