TREA

Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines

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Information

  • Patent Grant
  • 5824656
  • Patent Number
    5,824,656
  • Date Filed
    Friday, June 2, 1995
    29 years ago
  • Date Issued
    Tuesday, October 20, 1998
    26 years ago
Information
Abstract
Genes coding for novel Group B Eimeria tenella protein immunogens have been isolated and inserted into a novel expression vector which in turn has been used to transform appropriate hosts. The transformed host cells produce recombinant Group B E. tenella proteins which are capable of inducing immunity in chickens to coccidiosis.
Description
Claims
  • 1. A recombinant DNA molecule having a nucleotide sequence encoding an amino acid sequence of the Group B immunogen SO7 depicted in Table 8.
  • 2. The recombinant DNA molecule of claim 1 wherein the nucleotide sequence is the nucleotide sequence of clone SO7 depicted in Table 8.
  • 3. An immunogenic composition comprising the DNA of claim 1.
  • 4. A method of immunizing poultry against E. tenella induced coccidiosis comprising administering an therapeutically effective dose of the composition of claim 3.
RELATED U.S. APPLICATION DATA

This is a continuation-in-part of Ser. No. 08/087,914, filed Jul. 6, 1993, now abandoned, which is a continuation of Ser. No. 07/695,485, filed May 3, 1991, now abandoned, which is a continuation of Ser. No. 07/588,510, filed Sep. 21, 1990, now abandoned, which is a continuation of Ser. No. 07/286,936, filed Dec. 22, 1988, now abandoned, which is a continuation-in-part of Ser. No. 07/145,802, Jan. 15, 1988, now abandoned.

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WO 8806629 Mar 1988 WOX
WO 9204460 Sep 1991 WOX
WO 9204461 Sep 1991 WOX
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Continuations (4)
Number Date Country
Parent 695485 May 1991
Parent 588510 Sep 1990
Parent 286936 Dec 1988
Parent 145802 Jan 1988
Continuation in Parts (1)
Number Date Country
Parent 87914 Jul 1993