Regulation of Synthesis and Secretion of Brain Neuronal Cytokines

Information

• NSF Award
• 9017180

Owner

• NEW ENGLAND MEDICAL CENTER HOSPITALS, INC.

• Award Id

  9017180

• Award Effective Date

  7/1/1990 - 34 years ago

• Award Expiration Date

  6/30/1991 - 33 years ago

• Award Amount

  $ 16,277.00

• Award Instrument

  Standard Grant

Interlukins are important substances produced by the immune system. These substances, first discovered in white blood cells, have been implicated in a number of basic brain functions, such as sleep, disorientation, the production of fever and coma. This research will explore the regulation of neuronal interlukin metabolism, a problem of paramount importance in neuroscience. Dr. Reichlin will develop separate cultures of neurons and glia cells to test the effects of molecular probes, and to study the factors which influence the synthesis and secretion of neuronal interlukins in the brain. Results from this study will aid in understanding the role of interlukins in the brain.

• Program Officer

• Min Amd Letter Date

  6/26/1990 - 34 years ago

• Max Amd Letter Date

  6/26/1990 - 34 years ago

• ARRA Amount

• Name

  New England Medical Center Hospitals Incorporated

• City

  Boston

• State

  MA

• Country

  United States

• Address

  750 Washington St. Box 817

• Postal Code

  021111526

• Phone Number

  6176369914

• First Name

  Seymour

• Last Name

  Reichlin

• Start Date

  7/1/1990 12:00:00 AM

• Name

  Research Involving Recombinant DNA

• Code

  120000