Claims
- 1. A .beta.-hydroxyketo release tag compound having the structure ##STR26## wherein R.sup.1 =H, CF.sub.3, R, or OR;
- n=0-2;
- R=C1 to C8 alkyl, benzyl, or phenyl which can contain one or more H, D, or F;
- R.sup.5 =H or R;
- R.sup.6 =H or R; and
- CORx'=reactivity group.
- 2. A ketone compound having the structure ##STR27## wherein R.sup.1 =H, CF.sub.3, R, or OR;
- n=0-2; and
- R=C1 to C8 alkyl, benzyl, or phenyl which can contain one or more H, D, or F.
- 3. An olefin release tag compound having the structure ##STR28## wherein R.sup.1 =H, CF.sub.3, R, or OR;
- R.sup.5 =H or R;
- n=0-2;
- R=C1 to C8 alkyl, benzyl, or phenyl which can contain one or more H, D, or F; and
- Rx=reactivity group.
- 4. A glycol release tag compound having the structure ##STR29## wherein R.sup.1 =H, CF.sub.3, R or OR;
- R.sup.5 =H or R;
- n=0-2;
- R=C1 to C8 alkyl, benzyl, or phenyl which can contain one or more H, D, or F; and
- Rx=reactivity group.
- 5. An .alpha.-hydroxyketo release tag compound having the structure ##STR30## wherein R.sup.1 =H, CF.sub.3, R, or OR;
- n=0-2;
- R=C1 to C8 alkyl, benzyl, or phenyl which can contain one or more H, D, or F; and
- CORx'=reactivity group.
RELATED APPLICATIONS
This application is a division of application Ser. No. 08/053,608, filed Apr. 22, 1993, U.S. Pat. No. 5,516,931, which is a continuation-in-part of application Ser. No. 06/710,318 filed Mar. 11, 1985, now U.S. Pat. No. 5,360,819 which was a continuation-in-part of application Ser. No. 06/344,394 filed Feb. 1, 1982, now U.S. Pat. No. 4,709,016, the whole of which are hereby incorporated by reference herein.
US Referenced Citations (3)
Foreign Referenced Citations (1)
Number |
Date |
Country |
2185742 |
Jul 1987 |
GBX |
Non-Patent Literature Citations (7)
Entry |
Buchet et al., "Le dosage par chromatographie en phase gaseuse des m etabolites urinaires du trichlor ethylene: l'acide trichloroac etique et le trichloro ethanol," Archives de Maladies Professionelles, de M edecine due Travial et de S ecurit e Sociale (Paris), 35:395-402 (1974). |
Kawamatsu et al., Eur. J. Med. Chem. - Chim. Ther., 16(4) 355-362 [CA95(21): 187138c (1981)]. |
Landegren et al., "DNA Diagnostics - Molecular Techniques and Automation," Science 242:229-237 (1988). |
Rotman, "Sequencing the entire human genome," Industrial Chemist, pp. 18-21, Dec. 1987. |
Rudinger-Adler et al., "Arzneim.-Forsch.," 29(9) 1326-1331 [CA92(5): 41712b (1979)]. |
Senft, "Simple determination of trichloroacetic acid in urine using head space gas chromatography: a suitable method for monitoring exposure to trichloroethylene," Journal of Chromatography 337:126-130 (1985). |
Soloshonok, V. et al, Tetrahedron Lett (1994) 35(7) 1055-8. |
Divisions (1)
|
Number |
Date |
Country |
Parent |
53608 |
Apr 1993 |
|
Continuation in Parts (2)
|
Number |
Date |
Country |
Parent |
710318 |
Mar 1985 |
|
Parent |
344394 |
Feb 1982 |
|