REPBASE--A DATABASE OF REPETITIVE SEQUENCES

Information

  • Research Project
  • 2519677
  • ApplicationId
    2519677
  • Core Project Number
    P41LM006252
  • Full Project Number
    5P41LM006252-02
  • Serial Number
    6252
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/30/1996 - 28 years ago
  • Project End Date
    8/31/1999 - 25 years ago
  • Program Officer Name
    BEAN, CAROL A.
  • Budget Start Date
    9/1/1997 - 27 years ago
  • Budget End Date
    8/31/1998 - 26 years ago
  • Fiscal Year
    1997
  • Support Year
    2
  • Suffix
  • Award Notice Date
    8/25/1997 - 27 years ago

REPBASE--A DATABASE OF REPETITIVE SEQUENCES

DESCRIPTION: (Taken from project abstract) Repetitive DNA represents over 50% of eukaryotic genomes and contains a tremendous wealth of information about genomic structure and evolution. Its knowledge is of crucial importance for understanding complex relationships between genetic blueprints and their biological functions. It is also of practical significance for genome mapping and sequencing projects. Inevitably, researchers studying growing numbers of DNA sequences in the coming years will have to analyze increasing numbers of repetitive elements integrated within them in ever growing detail. There are at least three major aspects of such studies: (I) automatic annotation of repetitive DNA using reference collections of sequences of known repeats and specialized computer software; (ii) evaluation of particular repeats based on the existing biological information, and (iii) other specialized studies involving sequence context and properties of the repeats. Such studies will require electronically available and constantly updated database containing reference collections of repeats, description of the reference repeats organized in a condensed form, and specialized collections allowing detailed studies of available homologous repeats. The first database of repetitive DNA known as "Repbase" has been released by our group in 1992. Here we propose further steps necessary to improve and enhance this resource. Our specific goals include: 1. Develop and maintain reference collections of repetitive elements from all sequenced eukaryotic species. 2. Initiate a peer-reviewed electronic encyclopedia containing, updated key information on repetitive DNA. 3. Develop and maintain secondary collections of repetitive DNA.

IC Name
NATIONAL LIBRARY OF MEDICINE
  • Activity
    P41
  • Administering IC
    LM
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    879
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    BLR
  • Study Section Name
    Biomedical Library Review Committee
  • Organization Name
    GENETIC INFORMATION RESEARCH INSTITUTE
  • Organization Department
  • Organization DUNS
  • Organization City
    MOUNTAIN VIEW
  • Organization State
    CA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    940430808
  • Organization District
    UNITED STATES