Magnetic resonance imaging (MM), or nuclear magnetic resonance imaging, is a noninvasive imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field (modified with weak gradient fields applied across it to localize and encode or decode phases and frequencies) and body tissue to obtain projections, spectral signals, and images of planes or volumes from within a patient's body. Magnetic resonance imaging is particularly helpful in the imaging of soft tissues and may be used for the diagnosis of disease. Real-time or cine Mill may be used for the diagnosis of medical conditions requiring the imaging of moving structures within a patient. Real-time MM may also be used in conjunction with interventional procedures, such as radiation therapy or image guided surgery, and also in planning for such procedures.
Electromagnet designs are disclosed that may be utilized in magnetic resonance imaging systems. Certain embodiments may comprise a resistive, solenoidal electromagnet for whole-body Mill including conductors and ferromagnetic material within an envelope of the electromagnet. The electromagnet may be gapped and the ferromagnetic material may be steel. In some variations, the electromagnet may be configured for current flow in only one circumferential direction within the electromagnet.
The electromagnet may be configured as resistive, solenoidal electromagnet for whole-body Mill having a field strength of at least 0.05 Tesla comprising conductors for creating a main electromagnetic field of the electromagnet, where the main electromagnetic field is not generated by bundles of conductors. In some variations, the main electromagnetic field may be generated by layers of conductors (for example, less than 10 layers).
Electromagnet designs disclosed herein may utilize non-metallic formers for supporting conductors such as fiberglass formers. The layers of conductors and the non-metallic formers can be constructed to form a rigid object by fixing them together with an epoxy. The electromagnet can have two halves and the two halves can be held apart by a fixation structure, which may be made from carbon fiber. In one embodiment, conductors may be utilized that have a cross-sectional area greater than 0.5 centimeters squared.
In another embodiment, the magnetic resonance imaging system may include a resistive, solenoidal electromagnet for whole-body Mill having a field strength of at least 0.05 Tesla with conductors for creating a main electromagnetic field of the electromagnet that cover at least 50% of the envelope of the electromagnet.
In certain systems disclosed herein, the power supply for powering the resistive electromagnet can have more than one part per ten thousand current fluctuation at frequencies of 180 Hz or above and may not include a current filter separate from filtering provided by the resistive electromagnet itself. The power supply may also be a single channel power supply and may not include active current controls. In certain embodiments, the system can include a battery, where the resistive electromagnet can be connected to the battery and the system can be configured so that the battery can be charged by the power supply. The system can also include a fuel cell, where the system can be configured so that the fuel cell is located between the power supply and the resistive electromagnet.
Implementations of the current subject matter can include, but are not limited to, methods consistent with the descriptions provided herein as well as articles that comprise a tangibly embodied machine-readable medium operable to cause one or more machines (e.g., computers, etc.) to result in operations implementing one or more of the described features. Similarly, computer systems are also contemplated that may include one or more processors and one or more memories coupled to the one or more processors. A memory, which can include a computer-readable storage medium, may include, encode, store, or the like, one or more programs that cause one or more processors to perform one or more of the operations described herein. Computer implemented methods consistent with one or more implementations of the current subject matter can be implemented by one or more data processors residing in a single computing system or across multiple computing systems. Such multiple computing systems can be connected and can exchange data and/or commands or other instructions or the like via one or more connections, including but not limited to a connection over a network (e.g., the internet, a wireless wide area network, a local area network, a wide area network, a wired network, or the like), via a direct connection between one or more of the multiple computing systems, etc.
The details of one or more variations of the subject matter described herein are set forth in the accompanying drawings and the description below. Other features and advantages of the subject matter described herein will be apparent from the description and drawings, and from the claims. While certain features of the currently disclosed subject matter are described for illustrative purposes in relation to particular implementations, it should be readily understood that such features are not intended to be limiting. The claims that follow this disclosure are intended to define the scope of the protected subject matter.
The accompanying drawings, which are incorporated in and constitute a part of this specification, show certain aspects of the subject matter disclosed herein and, together with the description, help explain some of the principles associated with the disclosed implementations. In the drawings,
The present disclosure relates to technologies that may be utilized in various systems, devices, methods and computer software used with electromagnets. Certain embodiments of the technologies described herein may be beneficially employed in conjunction with magnets used for magnetic resonance imaging (MRI), although it is contemplated that these technologies may also be implemented in electromagnets for other applications.
One particular type of MRI magnet discussed herein as benefiting from these technologies is a solenoidal (i.e., cylindrical), resistive electromagnet (to be distinguished from, e.g., permanent magnets, superconducting electromagnets and non-solenoidal electromagnets such as dipolar electromagnets). When the term solenoid or solenoidal is used herein to describe a magnet, such refers merely to the so-named configuration of certain MRIs (i.e., cylindrical); it is not by any means limited to magnet configurations that might typically be described as a perfect solenoid (e.g., a single helically wound conductor). While these technologies herein can be used in any size MRI electromagnet, the main implementations discussed herein relate to magnets for whole-body MRI systems. When the term “whole-body” is used herein, it refers to typical size magnetic resonance imaging systems (e.g., the Siemens Healthineers Magnetom Aera and the GE Signa), instead of small MRIs for imaging particular body parts (such as the Esaote O-Scan), or those for veterinary applications, research, etc.
In the case of whole-body MRI electromagnets, is contemplated that the technologies herein can be used at any MM field strength, although imaging may suffer below 0.05 Tesla and power requirements can be high for resistive electromagnets above 0.5 Tesla. Two particular implementations for resistive, solenoidal electromagnets discussed herein have field strengths of 0.12 T and 0.2 T.
The technologies of the present disclosure can be used in traditional solenoidal MM systems used for diagnostic purposes, but can be particularly beneficial in gapped solenoidal systems, such as the system depicted in
While the technologies described herein are predominantly applied to electromagnets as used with MRI, these features may also be used with suitable magnet designs, regardless of purpose. For example, more general magnet systems can include those used in research, industry, or practical applications such as magnetic switching, motors, power generators, relays, speakers, magnetic separation equipment, etc.
The main electromagnet 102 of MRI 100 may be a gapped solenoidal electromagnet separated by buttresses 114 with a gap 116 as shown in
Gradient coil assembly 104 contains the coils necessary to add small varying magnetic fields on top of the field of main electromagnet 102 to allow for spatial encoding of the imaging data. Gradient coil assembly 104 may be a continuous cylindrical assembly, a split gradient coil assembly as shown in
RF coil system 106 is responsible for exciting the spins of hydrogen protons within patient 110 and for receiving subsequent signals emitted from patient 110. RF coil system 106 thus includes an RF transmitter portion and an RF receive portion. The implementation in
Magnetic resonance imaging systems include control systems configured for the acquisition and processing of magnetic resonance imaging data from patient 110, including image reconstruction. Such control systems may contain numerous subsystems, for example, those which control operation of the gradient coil assembly 104, the RF coil system 106, portions of those systems themselves, and those that process data received from RF coil system 106 and perform image reconstruction. Additional control system functionality can be included, for example, when an interventional device (such as a radiation therapy device) is integrated with MRI 100.
In a gapped magnet, as shown in
In the exemplary design of
Electromagnets are, of course, made with conductors, for example, loops of copper wire. As used herein, the term “conductors” refers to any conductive loops, coils or other structures that are used to generate the main magnetic field of an electromagnet. When the plural form of the word is used herein, it is intended to cover not only a plurality of conductors (e.g., separate coils or bundles of wire), but plural “conductors” may also refer to structures that are technically one continuous conductor but may comprise, for example, multiple conductive loops, turns or other structures.
One particular beneficial implementation of the present disclosure has ferromagnetic material included within the envelope of the electromagnet. An example of such is shown in
While the example of
The present disclosure contemplates that the layers of an electromagnet design similar to that of
The present disclosure contemplates many different configurations of ferromagnetic material within the envelope of electromagnet. While the example of
The present disclosure specifically contemplates its technologies being utilized in magnet designs that have no yoke and magnet designs that have no flux return. The “ferromagnetic material within the electromagnet envelope” magnet designs discussed herein are distinguishable from flux returns and yokes. For example, for a solenoidal magnet (as illustrated in
The present disclosure also specifically distinguishes magnets where the main magnetic field is generated primarily by a permanent magnet or magnets. While such systems may seem to include ferromagnetic material within their magnet's envelope, they are distinct from the technologies disclosed herein, which relate to electromagnets and define “within the envelope” as within the envelope of conductors used to generate the electromagnet's main magnetic field.
In an exemplary design, depicted in
It should be noted that the electromagnet designs contemplated herein may include additional ferromagnetic materials outside the envelope of the electromagnet, which are configured to reduce the fringe field of the electromagnet. An example of such fringe field reducing material 402 is illustrated in
It should also be noted that when an electromagnet is being utilized in conjunction with an interventional application that may require placement of ferromagnetic materials in or near the magnet, modeling for design and optimal homogeneity should take into account such materials as well.
One embodiment of the present disclosure made thus be a magnetic resonance imaging (MRI) system including a resistive, solenoidal electromagnet for whole-body MM including conductors and ferromagnetic material within an envelope of the electromagnet. The electromagnet may be gapped and the ferromagnetic material may comprise steel. In different embodiments, the volume of ferromagnetic material may be at least one sixth the volume of the conductors or at least one twentieth the volume of the conductors. In certain designs, the electromagnet may comprise a plurality of cylindrical layers and the ferromagnetic material may comprise a layer of the plurality of cylindrical layers. Alternatively, the ferromagnetic material may comprise a portion of a layer of the plurality of cylindrical layers. In still other embodiments, the ferromagnetic material may comprise a plurality of layers or a plurality of portions of layers of the plurality of cylindrical layers.
Many existing magnet designs, especially those for gapped solenoidal magnets, require currents within the electromagnet to flow in a positive direction and also in a negative direction in order to attain the desired homogeneity of the magnetic field. As used herein, a “positive” current flow is a flow direction that contributes positively to a magnet's main magnetic field Bo (see, e.g., positive flow direction 118 and main magnetic field 122 in
In electromagnets that rely on conductor bundles to create the main magnetic field, certain bundles may have positive current flows and other bundles may have negative current flows. Similarly, for the electromagnet design depicted at the bottom of
Using the technologies of the present disclosure, for example, magnet designs including ferromagnetic material within the magnet envelope, allows for magnet designs containing only positive current flows to produce satisfactorily homogeneous fields, even in gapped magnet configurations.
In some implementations of the present disclosure, a magnetic resonance imaging system may thus comprise a resistive, solenoidal electromagnet for whole-body MM including conductors and ferromagnetic material within an envelope of the electromagnet where the system may be gapped and the electromagnet may be configured for current flow in only one circumferential direction within the magnet. For example, each of the bundles driving the main magnetic field may have a positive current direction, or, in the case of a non-bundled design, each of the conductors (e.g., as depicted in the bottom of
In other embodiments, the electromagnet may be configured for less than 5% negative current flow or less than 10% negative current flow. For example, in the embodiment of
The reduction or elimination of negative current flows allows for lower power supply requirements in certain magnet designs. Certain implementations of such systems are discussed below and exemplary power supply sizes are provided. It should be understood that these particular system designs, and associated power supply sizes are merely exemplary and that other designs and power supply sizes, or ranges of sizes, are contemplated.
Certain implementations herein of a magnetic resonance imaging system can include a resistive, solenoidal electromagnet for whole-body Mill including conductors and ferromagnetic material within an envelope of a gapped electromagnet where the conductors are made of copper. Certain of such implementations, where the conductors are directly cooled, (e.g., coolant is flowed through the center of the conductor) can be configured for a field strength of at least 0.12 Tesla and a power supply of less than 30 kW or less than 45 kW, while others may be configured for a field strength of at least 0.2 Tesla and a power supply of less than 100 kW or less than 145 kW, and yet others may be configured for a field strength of at least 0.3 Tesla and a power supply of less than 210 kW or less than 300 kW. In implementations where the conductors are indirectly cooled (e.g., coolant is flowed around the conductors or the conductors are naturally cooled by the environment around them), such electromagnets may be configured for a field strength of at least 0.12 Tesla and a power supply of less than 35 kW or less than 50 kW, while others may be configured for a field strength of at least 0.2 Tesla and a power supply of less than 105 kW or less than 150 kW, and yet others may be configured for a field strength of at least 0.3 Tesla and a power supply of less than 230 kW or less than 330 kW.
Other implementations herein of a magnetic resonance imaging system can include a resistive, solenoidal electromagnet for whole-body Mill including conductors and ferromagnetic material within an envelope of a gapped electromagnet where the conductors are made of aluminum. Certain of such implementations where the conductors are directly cooled (e.g., coolant is flowed through the center of the conductor), can be configured for a field strength of at least 0.12 Tesla and a power supply of less than 45 kW or less than 65 kW, while others may be configured for a field strength of at least 0.2 Tesla and a power supply of less than 155 kW or less than 220 kW, and yet others may be configured for a field strength of at least 0.3 Tesla and a power supply of less than 335 kW or less than 480 kW. In implementations where the conductors are indirectly cooled (e.g., coolant is flowed around the conductors or the conductors are naturally cooled by the environment around them), such electromagnets may be configured for a field strength of at least 0.12 Tesla and a power supply of less than 50 kW or less than 70 kW, while others may be configured for a field strength of at least 0.2 Tesla and a power supply of less than 170 kW or less than 245 kW, and yet others may be configured for a field strength of at least 0.3 Tesla and a power supply of less than 365 kW or less than 520 kW.
The technologies of the present disclosure, as described above, can reduce power requirements and can result in reduced forces between the two halves of a gapped solenoidal electromagnet. With existing technology, gapped solenoidal electromagnets require substantial fixation structures in order to keep apart the two halves of the magnet, which are attracted to one another with considerable force. This must be done in a way that avoids any relative movement that could affect field homogeneity.
Examples of substantial fixation structures are depicted in
In certain implementations, the fixation structures contemplated herein may comprise carbon fiber or zero CTE carbon fiber.
When the technologies above are combined with a radiation therapy device, the combined system may be configured such that the radiation therapy device is directed to treat through the fixation structure. For example, the fixation structure may be a 0.5 cm thick uniform carbon fiber cylinder between the magnet halves, with a coefficient of thermal expansion that is substantially zero and which provides minimal and uniform attenuation of a radiation therapy beam.
In yet another implementation, the fixation structure may be a single cylinder or continuous former that extends not just between the two magnet halves, but also into the electromagnet assembly itself (e.g., as a former between layers of conductors).
The technologies of the present disclosure can lower an electromagnet's current requirements and heating and also reduce forces exerted on a magnet's conductors and structures that support them. These technologies may thus facilitate certain types of beneficial magnet designs and construction methods. For example, in one particular implementation, a magnetic resonance imaging system having a resistive, solenoidal electromagnet for whole-body Mill with a field strength of at least 0.05 Tesla may include conductors for creating a main magnetic field of the electromagnet where the main magnetic field is not generated by bundles of conductors but instead may be generated by layers of conductors.
While cylindrical MRI systems commonly generate their main magnetic field using bundles (i.e., conductors wrapped together and placed at particular, distinct locations), certain implementations of the present disclosure provide for more distributed conductor arrangements, for example, distributed across layers. An example of such a layered conductor arrangement is depicted in
When the present disclosure refers to main magnetic field generation using conductors configured in a “layer,” such refers to, for example, conductor loops or coils arranged in a generally cylindrical shape at a radius of the electromagnet, which traverse the majority of the length of the electromagnet (or, in the case of a gapped magnet, the majority of the length of the half of the electromagnet).
A main magnetic field can be generated by multiple layers of conductors, as depicted in
In another implementation, 2 cm by 2 cm conductors may be utilized. In one particular implementation of a resistive, solenoidal electromagnet for whole-body Mill having a field strength of at least 0.05 Tesla and conductors for creating a main magnetic field of the electromagnet, the main magnetic field is generated by layers of conductors where the conductors have a cross-sectional area greater than 0.50 cm2 or greater than 0.75 cm2.
In some implementations, a portion of the conductors can have a smaller cross-sectional area than the cross-sectional area for other conductors. For example, a layer of smaller conductors may have approximately half the cross-sectional size of a layer of larger conductors (e.g., one layer's conductors may have a cross section of 40 mm×40 mm, and another layer may have conductors with a cross-section of 20 mm×20 mm). In some implementations, a layer or layers of smaller conductors may be implemented at or near the outer radial layer, or near or adjacent the ferromagnetic layer (e.g., L3 as shown in
Layered designs using the technologies of the present disclosure can avoid the need for substantial/strong metallic formers typically used with bundled designs and designs with higher current requirements. Thus, in some implementations, the conductors of the designs contemplated herein may be supported by lower strength materials such as fiberglass or plastic cylindrical formers. For example, the layers of conductors may be supported by 1 mm thick cylindrical fiberglass formers in-between layers, and the conductor layers and formers may be combined into a single rigid object through the use of an epoxy or other insulating material.
In one particular implementation, a resistive, solenoidal electromagnet for whole-body Mill, having a field strength of at least 0.05 Tesla, can include conductors for creating a main magnetic field of the electromagnet, where the main magnetic field is generated by layers of conductors and where the electromagnet utilizes non-metallic formers for supporting conductors, for example, fiberglass formers. One implementation includes at least two solenoidal layers of conductors separated by a nonmetallic former. Another implementation may include less than 10 layers of conductors. In yet another implementation, the layers of conductors and non-metallic formers may be constructed to form a rigid object, for example, by fixing them together with an epoxy. In still another implementation, the rigid object can further include at least a portion of a gradient coil. For example, just the slice select coil may be incorporated or, alternatively, the entire gradient coil may be epoxied together with the main magnet into a single rigid object.
The present disclosure contemplates indirect cooling systems having various types of cooling channels, for example, saddle-shaped circular loops, helical loops, a serpentine shape, etc. As shown in
A serpentine channel 720 will include an inlet and outlet (e.g., 726) for flowing coolant through the channel. In some implementations, the inlets and/or outlets can be located at a particular end 730 of the electromagnet that may be more accessible for establishing cooling connections. For example, inlets and outlets may be located at a patient end or a service end of the electromagnet.
When the present disclosure refers to a solenoidal electromagnet or refers to a solenoidal layer of conductors within an electromagnet, it is contemplated that the conductors may deviate somewhat from a perfect solenoid (i.e., a uniform, helically wound coil). For example, a layer of conductors may include S-bends (illustrated as element 602 in
S-bend configurations are an alternative to helical configurations. In addition to having a different manufacturing process, they can be modeled more effectively during magnet design if the software used for modeling simplifies current loops as pure “rings” of current (in which case, S-bend designs will more closely match the model than helical designs).
As referred to herein, an “S-bend” may take the form of a stretched-out letter S, as shown in the figures, but the term is intended to cover any gradual or sharp transition (even a 90 degree turn) to a subsequent loop that results in current flow in the subsequent loop continuing in the same circumferential direction. S-bends are distinguished from helical arrangements and also from U-bends, which result in current flow of the subsequent loop going in the opposite direction.
As previously discussed, certain electromagnet designs may include negative currents therein (i.e., those which create a magnetic field counteracting the direction of the main magnetic field). If such negative currents are required, they can be implemented in the coils of the present disclosure utilizing U-bends. As noted, however, negative currents may be avoided using the technologies of the present disclosure, including the inclusion of ferromagnetic material within the envelope of the electromagnet.
In certain implementations, conductors may also be arranged so that a conductor traverses a layer in a direction parallel to the axis of the solenoidal electromagnet. Such an arrangement is depicted as 604 in
In one particular implementation, a resistive, solenoidal electromagnet for whole-body Mill having a field strength of at least 0.05 Tesla can include conductors for creating a main magnetic field of the electromagnet, where the main magnetic field is generated by layers of conductors and where the layers of conductors include at least one layer including a section where a conductor traverses in a direction parallel to an axis of the solenoidal electromagnet and where the conductor may have a cross-sectional area greater than 0.50 cm2 or greater than 0.75 cm2.
In some implementations, the layers of conductors may include a first layer that is a helically wrapped conductor having a first helical tilt and a second layer, adjacent to the first layer, comprising a helically wrapped conductor having a second helical tilt, where the second helical tilt is opposite to the first helical tilt. In other words, certain implementations may have a layer that is a helically wound conductor tilting to the right and the layer just inside or outside of that layer (i.e., the layer adjacent at the immediately smaller or larger radius) is a helically wound conductor tilting to the left.
In other implementations that are similarly designed to facilitate the production of a homogeneous magnetic field, the layers of conductors may include a first layer of wrapped conductor having first S-bends bending in a first direction and a second layer, adjacent to the first layer, comprising a wrapped conductor having second S-bends bending in a second direction where the first S-bends and the second S-bends overlap and where the second direction is opposite to the first direction. An example of such a configuration is depicted at the bottom of
In exemplary magnet designs of the present disclosure, multiple layers of conductors can be connected (for example, L1, L2, L4, L5 and L6 of
Implementations of this type of design may also include ferromagnetic material within the magnet envelope, as previously discussed. One example of such is depicted as ferromagnetic material 906 in
Electromagnets, especially those used in magnetic resonance imaging, can be required to produce highly homogeneous and stable magnetic fields. Such stability is commonly facilitated by the use of sophisticated DC power supplies that maintain highly stable voltage and current outputs (for example, on the order of only parts per million fluctuation). However, the technologies of the present disclosure can provide for homogeneous and stable magnetic fields without the need for such complex power supply designs. These technologies are applicable to different magnet configurations such as traditional solenoidal (ungapped) magnets, gapped solenoidal systems, dipolar magnets, etc.
When the present disclosure refers to electromagnets for magnetic resonance imaging, it is presumed that such magnets and their power supplies are configured to result in the requisite imaging field homogeneity and stability required for such MR imaging (e.g., on the order of parts per million). When “power supply(-ies)” are referred to herein, this terminology is intended to cover the electronics responsible for supplying the electromagnet with its requisite power including any associated electronics for rectification, filtering, control, etc. it is contemplated that such electronics may be present in a single unit or may be dispersed in different locations or modules. It is also understood herein that power supplies can be configured to provide a single current or may be multi-channel power supplies to provide multiple, potentially differing, currents.
While power supplies for MRI systems are typically designed to provide DC current with fluctuations on the order of only parts per million, the technologies of the present disclosure can provide the requisite field homogeneity and stability with a power supply having, e.g., only part per ten thousand stability. In one example, this stability metric can relate to the DC current ripple that exists, after rectification, at the original AC frequency and harmonics thereof. For example, implementations of the present disclosure may utilize a power supply having at least one part per ten thousand current fluctuation at frequencies of 180 Hz or above, or at frequencies of 600 Hz or above. Other implementations may even utilize power supplies having at least one part per thousand current fluctuation at frequencies of 180 Hz or above, or at frequencies of 600 Hz or above.
The relatively high current fluctuations in such power supplies can be filtered out essentially via the complex impedance of the wound metal conductors in various of the electromagnet designs disclosed herein. In one particular example discussed below, an exemplary electromagnet can filter current fluctuations of 15 parts per ten thousand over 600 Hz down to a level of −90 dB. Implementations of the present disclosure can thus include magnetic resonance imaging systems that do not include a current filter separate from the filtering provided by the resistive electromagnet itself. Stated another way, such a system does not include an additional element added for the purpose of reducing current fluctuation (e.g., the addition of an inductor).
Alternative implementations may include a current filter but can limit such filters to having less than, for example, 5 mH, 2 mH or 1 mH inductance. One particular implementation of a magnetic resonance imaging system can thus include a resistive electromagnet for whole-body MRI having a field strength of at least 0.05 Tesla and a power supply for powering the resistive electromagnet having at least one part per ten thousand current fluctuation at frequencies of 180 Hz or above and either no current filter separate from the filtering provided by the resistive electromagnet itself, or a current filter of less than 2 mH inductance.
Certain implementations of the technologies described herein also enable the use of single-channel power supplies. For example, certain electromagnet designs described herein as having ferromagnetic material within their magnet envelope can be supplied with a single current. As noted above, these magnet designs can be optimized, for example, to avoid a need for negative currents and/or bundles of conductors that must be supplied with differing amounts of current. As a result, simplified, single-channel power supplies can be used that do not require complex control systems to keep multiple power channels in sync with one another. Furthermore, low-frequency current fluctuations from a single-channel power supply can be more easily handled by MRI control systems accounting for such variations than fluctuations from multichannel power supplies. For example, an MRI's spectrometer may be utilized to compensate for low-frequency drifts in current or voltage through main magnetic field strength corrections.
In certain implementations, these power supplies can be used with the exemplary gapped solenoidal magnet designs discussed above. For example, in an implementation utilizing directly cooled aluminum conductors where the electromagnet has a field strength of at least 0.12 Tesla, the power supply can be designed to provide a power of only 45 kW, or even less. Or, a power supply of 155 kW or less may be used for such a design and a field strength of at least 0.2 Tesla. Other configurations as taught or specifically discussed herein are contemplated.
While even single-channel power supplies for Mills typically require complex control systems to minimize current and voltage fluctuations, the present disclosure contemplates the use of a power supply that does not include active current controls, (e.g., the utilization of current feedback loops).
Implementations of the present disclosure contemplate the addition of a simple filter to control voltage fluctuations, for example, an LC filter. In one exemplary implementation, similar to the designs disclosed above, a solenoidal electromagnet having a gap of 28 cm configured for whole body MRI with a field strength of at least 0.12 Tesla is considered, and is made with ferromagnetic material within the magnet envelope and directly cooled aluminum conductors. An exemplary filter for such a design is depicted in
These equations represent the transfer function (dynamic response) of the system. A Bode plot of the magnitude can show the magnitude response as a function of the frequency (the high frequency components are effectively filtered). Such plots (or equivalent calculations of the transfer function) can be implemented to design the filter to reduce the magnitude of the ripple at unwanted frequencies above a low frequency cut off.
In alternative implementations, a battery or multiple batteries may be utilized in the system to at least partially limit the power supply fluctuations. Such may be utilized in addition to or instead of the filters discussed above. In one implementation, the electromagnet may be connected to and essentially powered by the battery and the system can be configured so that the battery can be charged by the power supply.
Power fluctuations at the electromagnet that may be caused by the power supply charging the battery can be avoided by other implementations utilizing multiple batteries (e.g., two or more). In such implementations, the battery responsible for powering the electromagnet can avoid being charged while it is powering the magnet and then, when the battery powering the electromagnet needs to be charged, the power source for the electromagnet can be switched to a different battery that has already been charged. Stated another way, the system may be configured such that the resistive electromagnet can be connected to one of a plurality of batteries while another of the plurality of batteries can be charged by the power supply.
Another example of a multi-battery embodiment is depicted in
If desired, as shown at the bottom of
While a battery or multiple batteries may be used to shield an electromagnet from power source fluctuations, the present disclosure also contemplates the use of a fuel-cell in a similar manner. For example, as depicted in
One or more aspects or features of the subject matter described herein can be realized in digital electronic circuitry, integrated circuitry, specially designed application specific integrated circuits (ASICs), field programmable gate arrays (FPGAs) computer hardware, firmware, software, and/or combinations thereof. These various aspects or features can include implementation in one or more computer programs that are executable and/or interpretable on a programmable system including at least one programmable processor, which can be special or general purpose, coupled to receive data and instructions from, and to transmit data and instructions to, a storage system, at least one input device, and at least one output device. The programmable system or computing system may include clients and servers. A client and server are generally remote from each other and typically interact through a communication network. The relationship of client and server arises by virtue of computer programs running on the respective computers and having a client-server relationship to each other.
These computer programs, which can also be referred to programs, software, software applications, applications, components, or code, include machine instructions for a programmable processor, and can be implemented in a high-level procedural language, an object-oriented programming language, a functional programming language, a logical programming language, and/or in assembly/machine language. As used herein, the term “machine-readable medium” (or “computer readable medium”) refers to any computer program product, apparatus and/or device, such as for example magnetic discs, optical disks, memory, and Programmable Logic Devices (PLDs), used to provide machine instructions and/or data to a programmable processor, including a machine-readable medium that receives machine instructions as a machine-readable signal. The term “machine-readable signal” (or “computer readable signal”) refers to any signal used to provide machine instructions and/or data to a programmable processor. The machine-readable medium can be a non-transitory, machine-readable medium that can store such machine instructions non-transitorily, such as for example as would a non-transient solid-state memory or a magnetic hard drive or any equivalent storage medium. The machine-readable medium can alternatively or additionally store such machine instructions in a transient manner, such as for example as would a processor cache or other random access memory associated with one or more physical processor cores.
To provide for interaction with a user, one or more aspects or features of the subject matter described herein can be implemented on a computer having a display device, such as for example a cathode ray tube (CRT) or a liquid crystal display (LCD) or a light emitting diode (LED) monitor for displaying information to the user and a keyboard and a pointing device, such as for example a mouse or a trackball, by which the user may provide input to the computer. Other kinds of devices can be used to provide for interaction with a user as well. For example, feedback provided to the user can be any form of sensory feedback, such as for example visual feedback, auditory feedback, or tactile feedback; and input from the user may be received in any form, including, but not limited to, acoustic, speech, or tactile input. Other possible input devices include, but are not limited to, touch screens or other touch-sensitive devices such as single or multi-point resistive or capacitive trackpads, voice recognition hardware and software, optical scanners, optical pointers, digital image capture devices and associated interpretation software, and the like.
In the descriptions above and in the claims, phrases such as “at least one of” or “one or more of” may occur followed by a conjunctive list of elements or features. The term “and/or” may also occur in a list of two or more elements or features. Unless otherwise implicitly or explicitly contradicted by the context in which it used, such a phrase is intended to mean any of the listed elements or features individually or any of the recited elements or features in combination with any of the other recited elements or features. For example, the phrases “at least one of A and B;” “one or more of A and B;” and “A and/or B” are each intended to mean “A alone, B alone, or A and B together.” A similar interpretation is also intended for lists including three or more items. For example, the phrases “at least one of A, B, and C;” “one or more of A, B, and C;” and “A, B, and/or C” are each intended to mean “A alone, B alone, C alone, A and B together, A and C together, B and C together, or A and B and C together.” Use of the term “based on,” above and in the claims is intended to mean, “based at least in part on,” such that an unrecited feature or element is also permissible.
The subject matter described herein can be embodied in systems, apparatus, methods, computer programs and/or articles depending on the desired configuration. Any methods or the logic flows depicted in the accompanying figures and/or described herein do not necessarily require the particular order shown, or sequential order, to achieve desirable results. The implementations set forth in the foregoing description do not represent all implementations consistent with the subject matter described herein. Instead, they are merely some examples consistent with aspects related to the described subject matter. Although a few variations have been described in detail above, other modifications or additions are possible. In particular, further features and/or variations can be provided in addition to those set forth herein. The implementations described above can be directed to various combinations and subcombinations of the disclosed features and/or combinations and subcombinations of further features noted above. Furthermore, above described advantages are not intended to limit the application of any issued claims to processes and structures accomplishing any or all of the advantages.
Additionally, section headings shall not limit or characterize the invention(s) set out in any claims that may issue from this disclosure. Further, the description of a technology in the “Background” is not to be construed as an admission that technology is prior art to any invention(s) in this disclosure. Neither is the “Summary” to be considered as a characterization of the invention(s) set forth in issued claims. Furthermore, any reference to this disclosure in general or use of the word “invention” in the singular is not intended to imply any limitation on the scope of the claims set forth below. Multiple inventions may be set forth according to the limitations of the multiple claims issuing from this disclosure, and such claims accordingly define the invention(s), and their equivalents, that are protected thereby.
This application claims priority to and the benefit of U.S. Provisional Application No. 62/672,525, filed May 16, 2018, titled “Resistive Electromagnet Systems and Methods,” and U.S. Provisional Application No. 62/677,546, filed May 29, 2018, titled “Resistive Electromagnet Design and Construction,” the contents of each are hereby incorporated by reference in their entirety.
Number | Name | Date | Kind |
---|---|---|---|
3428307 | Hunter | Feb 1969 | A |
4019059 | Brundin | Apr 1977 | A |
4233662 | LeMay | Nov 1980 | A |
4481657 | Larsson | Nov 1984 | A |
4589126 | Augustsson | May 1986 | A |
4612596 | Fox | Sep 1986 | A |
4694837 | Blakeley | Sep 1987 | A |
4766378 | Danby | Aug 1988 | A |
4771785 | Duer | Sep 1988 | A |
4851778 | Kaufman | Jul 1989 | A |
4987309 | Klasen | Jan 1991 | A |
5027818 | Bova | Jul 1991 | A |
5039867 | Nishihara | Aug 1991 | A |
5094837 | Bis | Mar 1992 | A |
5117829 | Miller | Jun 1992 | A |
5216255 | Weidlich | Jun 1993 | A |
5291169 | Ige | Mar 1994 | A |
5317616 | Swerdloff | May 1994 | A |
5327884 | Hardy | Jul 1994 | A |
5328681 | Kito | Jul 1994 | A |
5332908 | Weidlich | Jul 1994 | A |
5351280 | Swerdloff | Sep 1994 | A |
5363077 | Herd | Nov 1994 | A |
5365927 | Roemer | Nov 1994 | A |
5373844 | Smith | Dec 1994 | A |
5377678 | Dumoulin | Jan 1995 | A |
5378989 | Barber | Jan 1995 | A |
5391139 | Edmundson | Feb 1995 | A |
5412363 | Breneman et al. | May 1995 | A |
5412823 | Sitta | May 1995 | A |
5442675 | Swerdloff | Aug 1995 | A |
5443068 | Cline | Aug 1995 | A |
5458125 | Schweikard | Oct 1995 | A |
5511549 | Legg | Apr 1996 | A |
5513238 | Leber | Apr 1996 | A |
5537452 | Shepherd | Jul 1996 | A |
5538494 | Matsuda | Jul 1996 | A |
5547454 | Horn | Aug 1996 | A |
5555283 | Shiu | Sep 1996 | A |
5570022 | Ehnholm | Oct 1996 | A |
5585724 | Morich | Dec 1996 | A |
5596619 | Carol | Jan 1997 | A |
5602892 | Llacer | Feb 1997 | A |
5602982 | Llacer | Feb 1997 | A |
5647361 | Damadian | Jul 1997 | A |
5659281 | Pissanetzky | Aug 1997 | A |
5708362 | Frese | Jan 1998 | A |
5722411 | Suzuki | Mar 1998 | A |
5724400 | Swerdloff | Mar 1998 | A |
5734384 | Yanof | Mar 1998 | A |
5740225 | Nabatame | Apr 1998 | A |
5748700 | Shepherd | May 1998 | A |
5751781 | Brown | May 1998 | A |
5757881 | Hughes | May 1998 | A |
5790996 | Narfstrom | Aug 1998 | A |
5802136 | Carol | Sep 1998 | A |
5815547 | Shepherd | Sep 1998 | A |
5851182 | Sahadevan | Dec 1998 | A |
5894503 | Shepherd | Apr 1999 | A |
5936502 | Englund | Aug 1999 | A |
5952830 | Petropoulos | Sep 1999 | A |
5993373 | Nonaka | Nov 1999 | A |
6005916 | Johnson | Dec 1999 | A |
6011393 | Kaufman | Jan 2000 | A |
6038283 | Carol | Mar 2000 | A |
6052430 | Siochi | Apr 2000 | A |
6094760 | Nonaka | Aug 2000 | A |
6104779 | Shepherd | Aug 2000 | A |
6112112 | Gilhuijs | Aug 2000 | A |
6125335 | Simon | Sep 2000 | A |
6144875 | Schweikard | Nov 2000 | A |
6175761 | Frandsen | Jan 2001 | B1 |
6198957 | Green | Mar 2001 | B1 |
6207952 | Kan | Mar 2001 | B1 |
6223067 | Vilsmeier | Apr 2001 | B1 |
6240162 | Hernandez-Guerra | May 2001 | B1 |
6260005 | Yang | Jul 2001 | B1 |
6273858 | Fox | Aug 2001 | B1 |
6278891 | Reiderman | Aug 2001 | B1 |
6311389 | Uosaki | Nov 2001 | B1 |
6314159 | Siochi | Nov 2001 | B1 |
6330300 | Siochi | Dec 2001 | B1 |
6349129 | Siochi | Feb 2002 | B1 |
6366798 | Green | Apr 2002 | B2 |
6373250 | Tsoref | Apr 2002 | B1 |
6381486 | Mistretta | Apr 2002 | B1 |
6385286 | Fitchard | May 2002 | B1 |
6385477 | Werner | May 2002 | B1 |
6393096 | Carol | May 2002 | B1 |
6405072 | Cosman | Jun 2002 | B1 |
6411675 | Llacer | Jun 2002 | B1 |
6414487 | Anand | Jul 2002 | B1 |
6414490 | Timothy | Jul 2002 | B1 |
6422748 | Shepherd | Jul 2002 | B1 |
6424856 | Vilsmeier | Jul 2002 | B1 |
6456076 | Joseph | Sep 2002 | B1 |
6459769 | Cosman | Oct 2002 | B1 |
6466813 | Shukla | Oct 2002 | B1 |
6487435 | Mistretta | Nov 2002 | B2 |
6504899 | Pugachev | Jan 2003 | B2 |
6512813 | Krispel | Jan 2003 | B1 |
6512942 | Burdette | Jan 2003 | B1 |
6516046 | Frohlich | Feb 2003 | B1 |
6526123 | Ein-Gal | Feb 2003 | B2 |
6527443 | Vilsmeier | Mar 2003 | B1 |
6542767 | McNichols | Apr 2003 | B1 |
6546073 | Lee | Apr 2003 | B1 |
6560311 | Shepard | May 2003 | B1 |
6564084 | Allred | May 2003 | B2 |
6570475 | Lvovsky | May 2003 | B1 |
6584174 | Schubert | Jun 2003 | B2 |
6591127 | McKinnon | Jul 2003 | B1 |
6594516 | Steckner | Jul 2003 | B1 |
6600810 | Hughes | Jul 2003 | B1 |
6609022 | Vilsmeier | Aug 2003 | B2 |
6611700 | Vilsmeier | Aug 2003 | B1 |
6618467 | Ruchala | Sep 2003 | B1 |
6636645 | Yu | Oct 2003 | B1 |
6657391 | Ding | Dec 2003 | B2 |
6661870 | Kapatoes | Dec 2003 | B2 |
6708054 | Shukla | Mar 2004 | B2 |
6719683 | Frohlich | Apr 2004 | B2 |
6724922 | Vilsmeier | Apr 2004 | B1 |
6728336 | Bortfeld | Apr 2004 | B2 |
6731970 | Schlossbauer | May 2004 | B2 |
6735277 | McNutt | May 2004 | B2 |
6757355 | Siochi | Jun 2004 | B1 |
6772002 | Schmidt | Aug 2004 | B2 |
6778850 | Adler | Aug 2004 | B1 |
6792074 | Erbel | Sep 2004 | B2 |
6849129 | Bilz et al. | Feb 2005 | B2 |
6853704 | Collins | Feb 2005 | B2 |
6859660 | Vilsmeier | Feb 2005 | B2 |
6862469 | Bucholz | Mar 2005 | B2 |
6865253 | Blumhofer | Mar 2005 | B2 |
6865411 | Erbel | Mar 2005 | B2 |
6879714 | Hutter | Apr 2005 | B2 |
6885886 | Bauch | Apr 2005 | B2 |
6891375 | Goto | May 2005 | B2 |
6891924 | Yoda | May 2005 | B1 |
6898456 | Erbel | May 2005 | B2 |
6915005 | Ruchala | Jul 2005 | B1 |
6937696 | Mostafavi | Aug 2005 | B1 |
6940281 | Feenan | Sep 2005 | B2 |
6947582 | Vilsmeier | Sep 2005 | B1 |
6965847 | Wessol | Nov 2005 | B2 |
6980679 | Jeung | Dec 2005 | B2 |
6999555 | Morf | Feb 2006 | B2 |
7012385 | Kulish | Mar 2006 | B1 |
7046762 | Lee | May 2006 | B2 |
7046765 | Wong | May 2006 | B2 |
7046831 | Ruchala | May 2006 | B2 |
7050845 | Vilsmeier | May 2006 | B2 |
7092573 | Luo | Aug 2006 | B2 |
7095823 | Topolnjak | Aug 2006 | B2 |
7096055 | Schweikard | Aug 2006 | B1 |
7123758 | Jeung | Oct 2006 | B2 |
7130372 | Kusch | Oct 2006 | B2 |
7154991 | Earnst | Dec 2006 | B2 |
7162005 | Bjorkholm | Jan 2007 | B2 |
7166852 | Saracen | Jan 2007 | B2 |
7171257 | Thomson | Jan 2007 | B2 |
7180366 | Roos | Feb 2007 | B2 |
7191100 | Mostafavi | Mar 2007 | B2 |
7202663 | Huang | Apr 2007 | B2 |
7204640 | Fu | Apr 2007 | B2 |
7221733 | Takai | May 2007 | B1 |
7227925 | Mansfield | Jun 2007 | B1 |
7230429 | Huang | Jun 2007 | B1 |
7231075 | Raghavan | Jun 2007 | B2 |
7231076 | Fu | Jun 2007 | B2 |
7260426 | Schweikard | Aug 2007 | B2 |
7265545 | Krueger | Sep 2007 | B2 |
7266175 | Romesberg | Sep 2007 | B1 |
7266176 | Allison | Sep 2007 | B2 |
7289599 | Seppi | Oct 2007 | B2 |
7298819 | Dooley | Nov 2007 | B2 |
7302038 | Mackie | Nov 2007 | B2 |
7315636 | Kuduvalli | Jan 2008 | B2 |
7317782 | Bjorkholm | Jan 2008 | B2 |
7318805 | Schweikard | Jan 2008 | B2 |
7324626 | Vilsmeier | Jan 2008 | B2 |
7327865 | Fu | Feb 2008 | B2 |
7366278 | Fu | Apr 2008 | B2 |
7394081 | Okazaki | Jul 2008 | B2 |
7403638 | Jeung | Jul 2008 | B2 |
7412029 | Myles | Aug 2008 | B2 |
7415095 | Wofford | Aug 2008 | B2 |
7417434 | Overweg | Aug 2008 | B2 |
7423273 | Clayton | Sep 2008 | B2 |
7426318 | Fu | Sep 2008 | B2 |
7444178 | Goldbach | Oct 2008 | B2 |
7463823 | Birkenbach | Dec 2008 | B2 |
7471813 | Ulmer | Dec 2008 | B2 |
7477776 | Lachner | Jan 2009 | B2 |
7480399 | Fu | Jan 2009 | B2 |
7489131 | Lvovsky | Feb 2009 | B2 |
7505037 | Wang | Mar 2009 | B2 |
7505617 | Fu | Mar 2009 | B2 |
7522779 | Fu | Apr 2009 | B2 |
7532705 | Yin | May 2009 | B2 |
7542622 | Angelini | Jun 2009 | B1 |
7558617 | Vilsmeier | Jul 2009 | B2 |
7570987 | Raabe | Aug 2009 | B2 |
7577474 | Vilsmeier | Aug 2009 | B2 |
7589326 | Mollov | Sep 2009 | B2 |
7634122 | Bertram | Dec 2009 | B2 |
7636417 | Bjorkholm | Dec 2009 | B2 |
7638752 | Partain | Dec 2009 | B2 |
7657304 | Mansfield | Feb 2010 | B2 |
7659718 | Lustig | Feb 2010 | B1 |
7688998 | Tuma | Mar 2010 | B2 |
7728311 | Gall | Jun 2010 | B2 |
7741624 | Sahadevan | Jun 2010 | B1 |
7785358 | Lach | Aug 2010 | B2 |
7791338 | Kim | Sep 2010 | B2 |
7840045 | Guo | Nov 2010 | B2 |
7901357 | Boctor | Mar 2011 | B2 |
7902530 | Sahadevan | Mar 2011 | B1 |
7907987 | Dempsey | Mar 2011 | B2 |
7957507 | Cadman | Jun 2011 | B2 |
8139714 | Sahadevan | Mar 2012 | B1 |
8155417 | Piron | Apr 2012 | B2 |
8173983 | Sahadevan | May 2012 | B1 |
8190233 | Dempsey | May 2012 | B2 |
8214010 | Courtney | Jul 2012 | B2 |
8310233 | Trzasko | Nov 2012 | B2 |
8331531 | Fahrig | Dec 2012 | B2 |
8334697 | Overweg | Dec 2012 | B2 |
8378677 | Morich | Feb 2013 | B2 |
8460195 | Courtney | Jun 2013 | B2 |
8637841 | Prince | Jan 2014 | B2 |
8803524 | Dempsey | Aug 2014 | B2 |
8812077 | Dempsey | Aug 2014 | B2 |
8836332 | Shvartsman | Sep 2014 | B2 |
8896308 | Shvartsman | Nov 2014 | B2 |
8983573 | Carlone | Mar 2015 | B2 |
9082520 | Prince | Jul 2015 | B2 |
9114253 | Dempsey | Aug 2015 | B2 |
9289626 | Kawrakow | Mar 2016 | B2 |
9421398 | Shvartsman | Aug 2016 | B2 |
9423477 | Dempsey | Aug 2016 | B2 |
9446263 | Dempsey | Sep 2016 | B2 |
9472000 | Dempsey | Oct 2016 | B2 |
9526918 | Kruip | Dec 2016 | B2 |
9638773 | Poole | May 2017 | B2 |
20010049475 | Bucholz | Dec 2001 | A1 |
20020046010 | Wessol | Apr 2002 | A1 |
20020091315 | Spetz | Jul 2002 | A1 |
20020131556 | Steinberg | Sep 2002 | A1 |
20020150207 | Kapatoes | Oct 2002 | A1 |
20020151786 | Shukla | Oct 2002 | A1 |
20020193685 | Mate | Dec 2002 | A1 |
20030011451 | Katznelson | Jan 2003 | A1 |
20030057947 | Ni | Mar 2003 | A1 |
20030068097 | Wilson | Apr 2003 | A1 |
20030083901 | Bosch | May 2003 | A1 |
20030086526 | Clark | May 2003 | A1 |
20030112922 | Burdette | Jun 2003 | A1 |
20030155530 | Adnani | Aug 2003 | A1 |
20030181804 | Gagnon | Sep 2003 | A1 |
20030197507 | Liu | Oct 2003 | A1 |
20030219098 | McNutt | Nov 2003 | A1 |
20040030240 | Kimura | Feb 2004 | A1 |
20040054248 | Kimchy | Mar 2004 | A1 |
20040106869 | Tepper | Jun 2004 | A1 |
20040222795 | Dietz | Nov 2004 | A1 |
20040239327 | Heid | Dec 2004 | A1 |
20040254448 | Amies | Dec 2004 | A1 |
20040254773 | Zhang | Dec 2004 | A1 |
20050020917 | Scherch | Jan 2005 | A1 |
20050030028 | Clarke | Feb 2005 | A1 |
20050053267 | Mostafavi | Mar 2005 | A1 |
20050054916 | Mostafavi | Mar 2005 | A1 |
20050065431 | Reiderman | Mar 2005 | A1 |
20050143965 | Failla | Jun 2005 | A1 |
20050197564 | Dempsey | Sep 2005 | A1 |
20050201516 | Ruchala | Sep 2005 | A1 |
20050207531 | Dempsey | Sep 2005 | A1 |
20050254623 | Kamath | Nov 2005 | A1 |
20060033496 | Shvartsman | Feb 2006 | A1 |
20060058636 | Wemple | Mar 2006 | A1 |
20060074292 | Thomson | Apr 2006 | A1 |
20060120583 | Dewaele | Jun 2006 | A1 |
20060170679 | Wang | Aug 2006 | A1 |
20060193441 | Cadman | Aug 2006 | A1 |
20060280287 | Esham | Dec 2006 | A1 |
20060291621 | Yan | Dec 2006 | A1 |
20070003021 | Guertin | Jan 2007 | A1 |
20070016014 | Hara | Jan 2007 | A1 |
20070038058 | West | Feb 2007 | A1 |
20070043286 | Lu | Feb 2007 | A1 |
20070083114 | Yang | Apr 2007 | A1 |
20070086569 | Johnsen | Apr 2007 | A1 |
20070197908 | Ruchala | Aug 2007 | A1 |
20070216409 | Overweg | Sep 2007 | A1 |
20070230770 | Kulkarni | Oct 2007 | A1 |
20070244386 | Steckner | Oct 2007 | A1 |
20080033287 | Schwarze | Feb 2008 | A1 |
20080049897 | Molloy | Feb 2008 | A1 |
20080093567 | Gall | Apr 2008 | A1 |
20080108894 | Elgavish | May 2008 | A1 |
20080123927 | Miga | May 2008 | A1 |
20080177138 | Courtney | Jul 2008 | A1 |
20080197842 | Lustig | Aug 2008 | A1 |
20080208036 | Amies | Aug 2008 | A1 |
20080235052 | Node-Langlois | Sep 2008 | A1 |
20080259560 | Lvovsky | Oct 2008 | A1 |
20080303457 | Maltz | Dec 2008 | A1 |
20090039886 | White | Feb 2009 | A1 |
20090060130 | Wilkens | Mar 2009 | A1 |
20090129545 | Adler | May 2009 | A1 |
20090129659 | Deutschmann | May 2009 | A1 |
20090149735 | Fallone | Jun 2009 | A1 |
20090161826 | Gertner | Jun 2009 | A1 |
20090171184 | Jenkins | Jul 2009 | A1 |
20090175418 | Sakurai | Jul 2009 | A1 |
20090264768 | Courtney | Oct 2009 | A1 |
20090299170 | Gebhardt | Dec 2009 | A1 |
20100033186 | Overweg | Feb 2010 | A1 |
20100056900 | Whitcomb | Mar 2010 | A1 |
20100113911 | Dempsey | May 2010 | A1 |
20100119032 | Yan | May 2010 | A1 |
20100188082 | Morich | Jul 2010 | A1 |
20100239066 | Fahrig | Sep 2010 | A1 |
20100304976 | Overweg | Dec 2010 | A1 |
20100312095 | Jenkins | Dec 2010 | A1 |
20100312100 | Zarkh | Dec 2010 | A1 |
20100321019 | Imamura | Dec 2010 | A1 |
20100322497 | Dempsey | Dec 2010 | A1 |
20110012593 | Shvartsman | Jan 2011 | A1 |
20110018541 | Solf | Jan 2011 | A1 |
20110051893 | McNutt | Mar 2011 | A1 |
20110087090 | Boernert | Apr 2011 | A1 |
20110118588 | Komblau | May 2011 | A1 |
20110121832 | Shvartsman | May 2011 | A1 |
20110142887 | Har-Noy | Jun 2011 | A1 |
20110150180 | Balakin | Jun 2011 | A1 |
20110218420 | Carlone | Sep 2011 | A1 |
20110237859 | Kuhn | Sep 2011 | A1 |
20110241684 | Dempsey | Oct 2011 | A1 |
20110284757 | Butuceanu | Nov 2011 | A1 |
20120022363 | Dempsey | Jan 2012 | A1 |
20120043482 | Prince | Feb 2012 | A1 |
20120070056 | Krueger | Mar 2012 | A1 |
20120150017 | Yamaya | Jun 2012 | A1 |
20120157402 | Cao | Jun 2012 | A1 |
20120165652 | Dempsey | Jun 2012 | A1 |
20120245453 | Tryggestad | Sep 2012 | A1 |
20120253172 | Loeffler | Oct 2012 | A1 |
20130066135 | Rosa | Mar 2013 | A1 |
20130086163 | Neff | Apr 2013 | A1 |
20130090549 | Meltsner | Apr 2013 | A1 |
20130147476 | Shvartsman | Jun 2013 | A1 |
20130245425 | Dempsey | Sep 2013 | A1 |
20130261429 | Lee | Oct 2013 | A1 |
20130261430 | Uhlemann | Oct 2013 | A1 |
20130296687 | Dempsey | Nov 2013 | A1 |
20130345545 | Gross | Dec 2013 | A1 |
20130345556 | Courtney | Dec 2013 | A1 |
20140003023 | Weibler | Jan 2014 | A1 |
20140084926 | Amthor | Mar 2014 | A1 |
20140112453 | Prince | Apr 2014 | A1 |
20140121495 | Dempsey | May 2014 | A1 |
20140128719 | Longfield | May 2014 | A1 |
20140135615 | Krulp | May 2014 | A1 |
20140263990 | Kawrykow | Sep 2014 | A1 |
20140266206 | Dempsey | Sep 2014 | A1 |
20140266208 | Dempsey | Sep 2014 | A1 |
20140275963 | Shvartsman | Sep 2014 | A1 |
20140330108 | Dempsey | Nov 2014 | A1 |
20140336442 | Keppel | Nov 2014 | A1 |
20140347053 | Dempsey | Nov 2014 | A1 |
20150065860 | Shvartsman | Mar 2015 | A1 |
20150077118 | Shvartsman | Mar 2015 | A1 |
20150095044 | Hartman | Apr 2015 | A1 |
20150126850 | Cetingul | May 2015 | A1 |
20150154756 | Gerganov | Jun 2015 | A1 |
20150165233 | Dempsey | Jun 2015 | A1 |
20150185300 | Shvartsman | Jul 2015 | A1 |
20150273239 | Hsu | Oct 2015 | A1 |
20150346304 | Hu | Dec 2015 | A1 |
20160146911 | Chmielewski | May 2016 | A1 |
20160184609 | Dempsey | Jun 2016 | A1 |
20160232690 | Ahmad | Aug 2016 | A1 |
20160252596 | Nielsen | Sep 2016 | A1 |
20160256712 | Vahala | Sep 2016 | A1 |
20160334479 | Poole | Nov 2016 | A1 |
20160356869 | Dempsey | Dec 2016 | A1 |
20170001039 | Dempsey | Jan 2017 | A1 |
20170014644 | Shvartsman | Jan 2017 | A1 |
20170021198 | Kawrykow | Jan 2017 | A1 |
20170148536 | Kawrykow | May 2017 | A1 |
20170203126 | Dempsey | Jul 2017 | A1 |
20170231583 | Goteti Venkata | Aug 2017 | A1 |
20170252577 | Dempsey | Sep 2017 | A1 |
20170371001 | Dempsey | Dec 2017 | A1 |
20180021595 | Kesti-Helia | Jan 2018 | A1 |
20180078785 | Ollila | Mar 2018 | A1 |
20180078792 | Ollila | Mar 2018 | A1 |
20180133511 | Dempsey | May 2018 | A1 |
20180143274 | Poole | May 2018 | A1 |
20180185669 | Kuusela | Jul 2018 | A1 |
20180243584 | Nord | Aug 2018 | A1 |
20190083814 | Tallinen | Mar 2019 | A1 |
20190168028 | Dempsey | Jun 2019 | A1 |
20190217126 | Shvartsman | Jul 2019 | A1 |
20190353724 | Snelten | Nov 2019 | A1 |
20190353725 | Dempsey | Nov 2019 | A1 |
20200086143 | Maltz | Mar 2020 | A1 |
20200147412 | Ni | May 2020 | A1 |
20200246637 | Wang | Aug 2020 | A1 |
Number | Date | Country |
---|---|---|
1612713 | May 2005 | CN |
1669599 | Sep 2005 | CN |
1946339 | Apr 2007 | CN |
101000689 | Jul 2007 | CN |
101267858 | Sep 2008 | CN |
101268474 | Sep 2008 | CN |
101278361 | Oct 2008 | CN |
101443819 | May 2009 | CN |
102369529 | Mar 2012 | CN |
102472830 | May 2012 | CN |
102641561 | Aug 2012 | CN |
3828639 | Mar 1989 | DE |
1761794 | Mar 2007 | EP |
2359905 | Aug 2011 | EP |
2424430 | Jan 2013 | EP |
2839894 | Nov 2003 | FR |
2219406 | Dec 1989 | GB |
2219406 | Dec 1989 | GB |
2393373 | Mar 2004 | GB |
63294839 | Dec 1988 | JP |
06054916 | Jan 1994 | JP |
H07213507 | Aug 1995 | JP |
2001517132 | Oct 2001 | JP |
2002102198 | Apr 2002 | JP |
2002186676 | Jul 2002 | JP |
2002522129 | Jul 2002 | JP |
2005103295 | Apr 2005 | JP |
2006149560 | Jun 2006 | JP |
2007526036 | Sep 2007 | JP |
2009501043 | Jan 2009 | JP |
2009511222 | Mar 2009 | JP |
2009112870 | May 2009 | JP |
2009160309 | Jul 2009 | JP |
2009538195 | Nov 2009 | JP |
2010269067 | Dec 2010 | JP |
2015520631 | Jul 2015 | JP |
1999032189 | Jul 1999 | WO |
2000025864 | May 2000 | WO |
2002072190 | Sep 2002 | WO |
20030008986 | Jan 2003 | WO |
2004024235 | Mar 2004 | WO |
2005081842 | Sep 2005 | WO |
2005081842 | Sep 2005 | WO |
2006007277 | Jan 2006 | WO |
2006097274 | Sep 2006 | WO |
2007007276 | Jan 2007 | WO |
2007014105 | Feb 2007 | WO |
2007045076 | Apr 2007 | WO |
2007126842 | Nov 2007 | WO |
2008013598 | Jan 2008 | WO |
2008122899 | Oct 2008 | WO |
2009004521 | Jan 2009 | WO |
2009099001 | Aug 2009 | WO |
2009107005 | Sep 2009 | WO |
2009155700 | Dec 2009 | WO |
2009156896 | Dec 2009 | WO |
2010103644 | Sep 2010 | WO |
2010113050 | Oct 2010 | WO |
2011008969 | Jan 2011 | WO |
2012045153 | Apr 2012 | WO |
2012164527 | Dec 2012 | WO |
20150138945 | Sep 2015 | WO |
Entry |
---|
Weaver, John B.; “Simultaneous Multislice Acquisition of MR Images”, Magnetic Resonance in Medicine, John Wiley & Sons, Inc., vol. 8, No. 3, Nov. 1, 1988, pp. 275-284, XP000003030, ISSN: 0740-3194. |
Office Action dated Oct. 22, 2018 for U.S. Appl. No. 15/268,366 (pp. 1-8). |
Office Action dated Jan. 28, 2019 for U.S. Appl. No. 15/436,620 (pp. 1-17). |
Office Action dated Apr. 17, 2019 for U.S. Appl. No. 15/268,366 (pp. 1-6). |
Office Action dated Jun. 27, 2019 for U.S. Appl. No. 15/630,890 (pp. 1-7). |
Notice of Allowance dated Jul. 1, 2019 for U.S. Appl. No. 15/268,366 (pp. 1-5). |
Meyer, et al. “Fast Spiral Coronary Artery Imaging”, Magnetic Resonance in Medicine 28, pp. 202-213 (1992). |
Green et al. ‘Split cylindrical gradient coil for combined PET-MR system.’ Proc. Intl. Soc. Mag. Reson. Med. 16(2008):352. |
Lucas et al. ‘Simultaneous PET-MR: toward a combined microPET.RTM.-MR system.’ Proc. Intl. Soc. Mag. Reson. Med. 15(2007):922. |
Dverweg et al. ‘System for MRI guided Radiotherapy.’ Proc. Intl. Soc. Mag. Reson. Med. 17(2009):594. |
Shvartsman et al. ‘Gradient Coil Induced Eddy Current Computation Using the Boundary Elements Method.’ Proc. Intl. Soc. Mag. Reson. Med. 17(2009):3055. |
Gerganov G et al, ‘Portal image registration using the phase correlation method’, 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC), IEEE, (Oct. 27, 2013), doi:10.1109/NSSMIC.201 3.6829306, pp. 1-3, XP032601397. |
Extended European Search Report and supplementary European Search Opinion of European Patent application No. EP 10822326.2-1560, dated Aug. 2, 2013. |
International Search Report of PCT/US2010/057650 dated Feb. 2, 2011. |
Bilgin, A. et al. ‘Randomly Perturbed Radial Trajectories for Compressed Sensing MRI’ Proceedings of International Society for Magnetic Resonance in Medicine 16 (2008):3152. |
Blaimer, et al. ‘Smash, Sense, Pills, Grappa, How to Choose the Optimal Method’. Top Magan Reson Imaging, vol. 15, No. 4, Aug. 2004, pp. 223-236. |
Candes, et al. ‘Robust Uncertainty Principles: Exact Signal Reconstruction from Highly Incomplete Frequency Information.’ IEEE Transactions on Information Theory, vol. 52, No. 2, Feb. 2006, pp. 489-509. |
Candes, et al. ‘Sparsity and Incoherence in Compressive Sampling’. Electrical and Computer Engineering, Georgia Tech, Atlanta, GA, 90332. Nov. 2006, pp. 1-20. |
CIPRA ‘L1-magic’ from SIAM News, vol. 39, No. 9, Nov. 2006. (3 pages). |
Donoho, David L., ‘Compressed Sensing’. Department of Statistics, Stanford University. Sep. 14, 2004. (34 pages). |
Foroosh, Hassan, et.al. ‘Extension of Phase Correlation to Subpixel Registration.’ IEEE Transactions on Image Processing, vol. 11, No. 3, 2002, pp. 188-200. |
Haacke, Mark E. et al. ‘Constrained reconstruction: A superresolution, optimal signal-to-noise alternative to the Fourier transform in magnetic resonance imaging.’ Medical Physics, AIP, Melville, NY, US, vol. 16, No. 3, May 1, 1989 (May 1, 1989), pp. 388-397, XP000034068, ISSN: 0094-2405, DDI: 10.1118/1.596427. |
Irarrazabal, Pablo, and Dwight G. Nishimura. ‘Fast Three Dimensional Magnetic Resonance Imaging.’ Magnetic Resonance in Medicine, vol. 33, No. 5, 1995, pp. 656-662. |
Law, C. , and Glover, G. ‘Deconvolving Haemodynamic Response Function in fMRI under high noise by Compressive Sampling.’ Proceedings of International Society for Magnetic Resonance in Medicine. 17 (2009): 1712. Stanford University, Stanford, CA, United States. |
Lustig, M, et. al. ‘Faster Imaging with Randomly Perturbed, Undersampled Spirals and |L|_1 Reconstruction.’ In Proceedings of the 13th Annual Meeting of ISMRM, Miami Beach, 2005. (1 page). |
Reddy, B. Srinivasa, and B. N. Chatterji. ‘An FFT-Based Technique for Translation, Rotation, and Scale-Invariant Image Registration.’ IEEE Transactions on Image Processing, vol. 5, No. 8, Aug. 1996, pp. 1266-1271. |
Roullot Elodie et al. ‘Regularized reconstruction of 3D high-resolution magnetic resonance images from acquisitions of anisotropically degraded resolutions.’ Pattern Recognition, 2000. Proceedings. 15th International Conference on Sep. 3-7, 2000; [Proceedings of the International Conference on Pattern Recognition. (ICPR)], Los Alamitos, CA, USA,IEEE Comput. Soc, US, vol. 3, Sep. 3, 2000 (Sep. 3, 2000), pp. 346-349. |
Trzasko et al. ‘Highly Undersampled Magnetic Resonance Image Reconstruction via Homotopic L0—Minimization’ IEEE Transactions on Medical Imaging vol. 28. No. 1. Jan. 31, 2009, pp. 106-121. |
Yang, Junfeng, et. al. ‘A Fast TVL1-L2 Minimization Algorithm for Signal Reconstruction from Rartial Fourier Data.’ Technical Report, TR08-27, CAAM, Rice University Houston, TX, 2008. pp. 1-10. |
St. Aubin et al,, ‘Magnetic decoupling on the linac in a low field biplanar linac-MR system’, Med. Phys, 37 (9), Sep. 2010, pp. 4755-4761. |
Hernando, D. et al. ‘Interventional MRI with sparse sampling: an application of compressed sensing.’ Proceedings of International Society for Magnetic Resonance in Medicine. 16 (2008): 1482. |
PCT App. No. PCT/US2010/039036; International Search Report dated Aug. 11, 2010; (pp. 1-2). |
Lustig, et al. ‘L1 SPIR-IT: Autocalibrating Parallel Imaging Compressed Sensing.’ Electrical Engineering, Stanford University, Stanford, CA, United States Radiology, Stanford University Statistics, Stanford University (p. 334). |
International Search Report of the International Searching Authority issued in International Application No. PCT/US2014/028792, dated Jul. 2, 2014. |
Lagendijk et al., ‘MRI/linac integration’, Radiotherapy and Oncology, Elsevier, Ireland, (Nov. 26, 2007), vol. 86, No. 1, doi:10.1016/J.RADONC.2007.10.034, ISSN 0167-8140, pp. 25-29, XP022423061. |
Zitova B. et al., ‘Image Registration Methods: A Survey’, Image and Vision Computing, Elsevier, Guildford, GB, (Oct. 1, 2003), vol. 21, No. 11, doi:10.1016/S0262-8856(03)00137-9, ISSN 0262-8856, pp. 977-1000, XP001189327. |
Li, Kang and Kanadae, Takeo. ‘Nonnegative Mixed-Norm Preconditioning for Microscopy Image Segmentation.’ Information Processing in Medical Imaging. Springer Berlin Heidelberg vol. 5636. (2009):362-373. |
Riek, et al. “Flow Compensation in MRI Using a Phase-Corrected Real Reconstruction”, Magnetic Resonance in Medicine 30, pp. 724-731, 1993. |
Barth, et al. “Simultaneous Multislice (SMS) Imaging Techniques.” Magnetic Resonance in Medicine; vol. 75; pp. 63-81; 2016. |
EP App. No. 17000760.3; Extended EP Search Report dated Nov. 9, 2017. |
Lagendijk JJ W et al.: “MRI Guided Radiotherapy: A MRI based linear Accelerator”, Radiotherapy and Oncology, vol. 56, No. 01, Sep. 21, 2000 (Sep. 21, 2000), pp. S60-S61. |
Mah et al., “Measurement of intrafractional prostate motion using magnetic resonance imaging,” Int. J. Radiation Oneology Boil. Phys. Vo.54, No. 2, pp. 568-575, 2002. |
Anixter Inc. World Headquarters; “Wire Wisdom”; 2014 NEC 310.106 (B); 1 Page; 2016. |
Meulenbroeks, David; “Aluminum versus Copper Conductors—Application of Aluminum Conductors in Bus Way Systems for more Sustainable Data Centers”; Siemens Center of Competence Data Centers, The Netherlands; www.siemens.com/datacenter; White Paper Oct. 2014; 9 Pages. |
Pryor, Larry et a.: “A Comparison of Aluminum vs. Copper Used in Electrical Equipment”; 7 Pages. |
Morgan, Patrick N. et al.; “Resistive Homogeneous MRI Magnet Design by Matrix Subset Selection”; Magnetic Resonance in Medicine 41:1221-1229; Wiley-Liss, Inc. (1999). |
Momy, A. et al.; “Low-Leakage Wide-Access Magnet for MRI”; IEEE Transactions on Magnetics, vol. 33, No. Nov. 6, 1997; pp. 4572-4574. |
Lopez, Hector Sanchez et al.; “Designing an Efficient Resistive Magnet for Magnetic Resonance Imaging”; IEEE Transactions on Magnetics, vol. 40, No. 5; Sep. 2004; pp. 3378-3381. |
Sanchez, H. et al.; “Approach to Design an Efficient Resistive Magnet for MRI”; Proc. Intl. Soc. Mag, Reson. Med. 11(2003); p. 2409. |
Overweg, Johan; “MRI Main Field Magnets”; Philips Research; Hamburg, Germany; 7 Pages. |
Cosmus, Thomas C. et al.; “Advances in Whole-Body MRI Magnets”; IEEE/CSC & ESAS European Superconductivity New Forum (ESNF), No. 14; Oct. 2010; 6 Pages; The published version of this manuscript appeared in IEEE Transactions on Applied Superconductivity 21, Issue 3; pp. 2104-2109 (2011). |
Fofanov, Dr. Denis et al.; “Magentic Properties of Stainless Steels: Applications, Opportunities and New Developments”; https://steelmehdipour.net/wp-content/uploads/2017/02/Magnetic-properties-of-stainless-steels.pdf ; Webpage retrieved Feb. 2017; 13 Pages. |
English translation of WO 2009/099001 AI provided by Espacenet. 11 pages. |
Office Action dated Jan. 5, 2018 for U.S. Appl. No. 14/550,464 (pp. 1-21). |
Office Action dated Mar. 22, 2018 for U.S. Appl. No. 14/550,464 (pp. 1-22). |
Office Action dated Feb. 20, 2018 for U.S. Appl. No. 15/436,620 (pp. 1-25). |
Notice of Allowance dated Jul. 13, 2018 for U.S. Appl. No. 14/550,464 (pp. 1-11). |
PCT App. No. PCT/US2017/038867; International Search Report and Written Opinion dated Nov. 8, 2017; (pp. 1-12). |
Zaitsev M et al.: “Shared k-space Echo Planar Imaging with Keyhole,” Magnetic Resonance in Medicine, John Wiley & Sons, Inc. US, vol. 45, Jan. 1, 2001, pp. 109-117, XP002311925, ISSN: 0740-3194. |
B W Raaymakers et al.; “Integrating a 1.5 T MRI Scanner with a 6 MV Accelerator: Proof of Concepts,” Physics in Medicine and Biology. vol. 54, No. 12, May 19, 2009, pp. N229-N237, XP055395399, Bristol GB ISSN: 0031-9155. |
Jan J. W. Lagendijk et al.; “MR Guidance in Radiotherapy”, Physics in Medicine and Biology, Institute of Physics Publishing, Bristol GB, vol. 59, No. 21, Oct. 16, 2014, pp. R349-R369, XP020272054, ISSN: 0031-9155. |
Balter, James M., et al. ‘Accuracy of a Wireless Localization System for Radiotherapy’ Int. J. Radiation Oncology Biol. Phys., vol. 61, No. 3. pp. 933-937, Nov. 1, 2004, Elsevier Inc., USA. |
Baro, J et al. ‘Penelope: An algorithm for Monte Carlo simulation of the penetration and energy loss of electrons and positrons in matter’ Nuclear Instruments and Methods in Physics Research B 100 (1995) 31-46, received Sep. 30, 1994, Elsevier Science B.V. |
Bemier, Jacques et al. ‘Radiation oncology: a century of achievements’ Nature Reviews-Cancer, vol. 4, Sep. 2004. pp. 737-747. |
Buchanan, Roger ‘Cobalt on the way out’ British Medical Journal, vol. 292, Feb. 1, 1986. p. 290. |
Chng, N. et al. ‘Development of inverse planning and limited angle CT reconstruction for cobalt-60 tomotherapy’ Proceedings of 51st Annual Meeting of Canadian Organization of Medical Physicists and the Canadian College of Physicists in Medicine, 2005, McMaster University, Hamilton Ontario. Medical Physics, 2005, p. 2426. (4 pages). |
De Poorter J. et al. ‘Noninvasive MRI Thermometry with the Proton Resonance Frequencey (PRF) Method: In Vivo Results in Human Muscle,’ Magnetic Resonance in Medicine, Academic Press, Duluth, vol. 33, No. 1, Jan. 1995 pp. 74-81 XP000482971. |
Goitein, Michael. ‘Organ and Tumor Motion: An Overview.’ Seminars in Radiation Oncology. vol. 14, No. 1 Jan. 2004: pp. 2-9. |
Goldberg, S. Nahum; G. Scott Gazelle, and Peter R. Mueller. ‘Thermal Ablation Therapy for Focal Malignancy: A Unified Approach to Underlying Principles, Techniques, and Diagnostic Imaging Guidance.’ Amer. J. of Roentgenology, vol. 174, Feb. 2000 pp. 323-331 XP002431995. |
Golen et al., “A comparison of two scoring systems for late radiation toxicity in patients after radiotherapy for head and neck cancer,” Rep Pract Oncol Radiother, 2005; 10(4): 179-192. |
Hajdok, George. ‘An Investigation of Megavoltage Computed Tomography Using a Radioactive Cobalt-60 Gamma Ray Source for Radiation Therapy Treatment Verification.’ Thesis. May 2002. 150 pages. |
Hicks, et al., ‘Early FDG-PET imaging after radical radiotherapy for non-small-cell lung cancer: Inflammatory changes in normal tissues correlate with tumor response and do not confound therapeutic response evaluation’, International Journal of Radiation: Oncology Biology Physics; [Publication // Division of Scientific and Technical Information, International Atomic Energy Agency, ISSN 0074-1876 ; 1196], Pergamon Press, USA, (Oct. 1, 2004), vol. 60, No. 2, doi:10.1016/J.IJROBP.2004.03.036, ISSN 0360-3016, ISBN 978-92-0-107304-4, pp. 412-418, XP004582712. |
Hong J et al, ‘Interventional navigation for abdominal therapy based on simultaneous use of MRI and ultrasound’, Medical and Biological Engineering and Computing, Springer, Heildelberg, DE, vol. 44, No. 12, doi:10.1007/S11517-006-0133-2, ISSN 0140-0118, (Nov. 11, 2006), pp. 1127-1134, (Nov. 11, 2006), XP001551805. |
International Search Report and Written Opinion dated Apr. 13, 2012, for corresponding international application No. PCT/US2011/066605; 9 pages. |
Jaffray, David A., et al. ‘Flat-Panel Cone Beam Computed Tomography for Image-Guided Radiation Therapy’ Int. J. Radiation Oncology Biol. Phys., vol. 53, No. 5, pp. 1337-1349, Apr. 3, 2002, Elsevier Science Inc., USA. |
Jursinic, Paul et al. ‘Characteristics of secondary electrons produced by 6, 10 and 24 MV x-ray beams’ Phys. Med. Biol. 41 (1996) 1499-1509, United Kingdom. |
Khan, Faiz M., ‘The Physics of Radiation Therapy (second edition)’, Lippincott Williams & Wilkins. Chapter 13. 1985. pp. 323-332. |
Langen, K.M. et al. ‘Organ Motion and its Management.’ Int J. Radiation Oncology Biol. Phys., vol. 50, No. 1, pp. 265-278. 2001. Elsevier Science Inc., USA. |
Liang, J. and D. Yan. ‘Reducing Uncertainties in Volumetric Image Based Deformable Organ Registration.’ Medical Physics, vol. 30, No. 8, 2003, pp. 2116-2122. |
Lopez, Mike R. et al. ‘Relativistic Magnetron Driven by a Microsecond E-Beam Accelerator with a Ceramic Insulator’ IEEE Transactions on Plasma Science vol. 32, No. 3, Jun. 2004. pp. 1171-1180. |
Lurie, D.J., PhD. ‘Free radical imaging’ The British Journal of Radiology. 74 (2001). pp. 782-784. |
Macura, Katarzyna J., MD, PhD. ‘Advancements in Magnetic Resonance-Guided Robotic Interventions in the Prostate’. Top Magn Reson Imaging. vol. 19, No. 6. Dec. 2008. pp. 297-304. |
May et al., Abnormal Signal Intensity in Skeletal Muscle at MR Imaging: Patterns, Pearls, and Pitfalls, RadioGraphics 2000; 20: S295-S315. |
McMahon et al., Muscle Edema, AJR:194, Apr. 2010, W284-W292. |
Medtronic, Inc.. ‘Image-Guided Surgery Overview’. 2010. 2 pages. |
Mozer, Pierre C, MD, PhD. ‘Robotic Image-Guided Needle Interventions of the Prostate’. Reviews in Urology. vol. 11, No. 1. 2009. pp. 7-15. |
Muntener, Michael, MD et al. ‘Transperineal Prostate Intervention: Robot for fully Automated MR Imaging-System Description and Proof of Principle in a Canine Model’. Radiology. vol. 247, No. 2. May 2008. pp. 543-549. |
Nomayr A et al.; ‘MRI appearance of radiation-induced changes of normal cervical tissues’, Eur Radiol., (2001), vol. 11, No. 9, doi:doi:10.1007/s003300000728, pp. 1807-1817, XP055095676. |
Partial International Search Report Issued in International Application No. PCT/US2013/039009, dated Oct. 18, 2013. 2 pages. |
Pasternak et al., Free Water Elimination and Mapping from Diffusion, Magnetic Resonance in Medicine 62:717-730, 2009. |
Patriciu, Alexandru, et al., ‘Automatic Brachytherapy Seed Placement Under MRI Guidance’. IEEE Transactions on Biomedical Engineering. vol. 54, No. 8. Aug. 2007. pp. 1-8. |
PCT App. No. PCT/US2010/042156; International Search Report and Written Opinion dated Sep. 10, 2010 ; 15 pages. |
PCT App. No. PCT/US2016/063416; International Preliminary Report on Patentability and International Search Report with Written Option dated Jun. 7, 2018; 9 pages. |
PCT App. No. PCT/US2017/020015; International Search Report and Written Opinion dated Jul. 26, 2017; 18 pages. |
Raaijmakers, A.J.E. et al. ‘Integrating a MRI scanner with a 6 MV radiotherapy accelerator: dose increase at tissue-air interfaces in a lateral magnetic field due to returning electrons.’ Phys. Med. Biol. 50 (2005) pp. 1363-1376. |
Raaymakers, B.W et al. ‘Integrating a MRI scanner with a 6 MV radiotherapy accelerator: dose deposition in a transverse magnetic field’, Phys. Med. Biol. 49 (2004) 4109-4118. |
Rancati et al., NTCP Modeling of Subacute/Late Laryngeal Edema Scored by Fiberoptic Examination, Int. J. Radiation Oncology Biol. Rhys., vol. 75, No. 3, pp. 915-923, 2009. |
Sanguineti et al., Dosimetric Predictors of Laryngeal Edema, Int. J. Radiation Oncology Biol. Phys., vol. 68, No. 3, pp. 741-749, 2007. |
Schreiner, John; Kerr, Andrew; Salomons, Greg; Dyck, Christine, and Hajdok, George, ‘The Potential for Image Guided Radiation Therapy with Cobalt-60 Tomotherapy’, MICCAI 2003, LNCS 2879, pp. 449-456, 2003. |
Schreiner, L. John, et al. ‘The role of Cobalt-60 in modern radiation therapy: Dose delivery and image guidance’. Journal of Medical Physics, vol. 34, No. 3, 2009, 133-136. |
Sempau, Josep et al. ‘DPM, a fast, accurate Monte Carlo code optimized for photon and electron radiotherapy treatment planning dose calculations.’ Phys. Med. Biol. 45 (2000) pp. 2263-2291, Received Feb. 29, 2000. Printed in the UK. |
Sherouse, George W et al. ‘Virtual Simulation in the Clinical Setting: Some Practical Considerations’, Int. J. Radiation Oncology Biol. Phys. vol. 19, pp. 1059-1065, Apr. 26, 1990, Pergamon Press, USA. |
Stoianovici, Dan, et al. MRI Stealth ‘Robot for Prostate Interventions’. Minimally Invasive Therapy. 2007. pp. 241-248. |
Tamada and Kose. ‘Two-Dimensional Compressed Sensing Using the Cross-sampling Approach for Low-Field MRI Systems.’ IEEE Transactions on Medical Imaging. vol. 33, No. 9. Sep. 2014. pp. 1905-1912. |
Tokuda, J. et al. ‘Real-Time Organ Motion Tracking and Fast Image Registration System for MRI-Guided Surgery.’ Systems and Computers in Japan Scripta Technica USA. vol. 37, No. 1. Jan. 2006: 83-92. Database Inspec [Online]. The Institution of Electrical Engineers, Stevenage, GB; Jan. 2006. |
Tokuda, Junichi; Morikawa, Shigehiro; Dohi, Takeyoshi; Hata, Nobuhiko; Motion Tracking in MR-Guided Liver Therapy by Using Navigator Echoes and Projection Profile Matching, 2004. vol. 11. No. 1. pp. 111-120. |
Wang et al., Evolution of Radiation-Induced Brain Injury: MRI Imaging—Based Study, Radiology: vol. 254: No. 1; Jan. 2010 (9 pages). |
Warrington, Jim et al. ‘Cobalt 60 Teletherapy for Cancer: A Revived Treatment Modality for the 21st Century’, 2002 The Institution of Electrical Engineers, pp. 19-1-19/19. |
Wazer, David E. et al. ‘Principles and Practice of Radiation Oncology (fifth edition).’, Wolters Kluwer/Lippincott Williams & Wilkins. 2008. 2 pages. |
Webb, S. ‘The physical basis of IMRT and inverse planning’ The British Journal of Radiology, 76(2003), 678-689, 2003 The British Institute of Radiology. |
Webb, Steve, ‘Intensity-modulated radiation therapy using only jaws and a mask: II. A simplified concept of relocatable single-bixel attenuators’, published May 22, 2002, Institute of Physics Publishing, Physics in Medicine and Biology, Phys. Med. Biol. 47 (2002) 1869-1879. |
Webb, Steve. “Historical Perspective on IMRT.” Institute of Cancer Research and Royal Marsden NHS Trust. 2002. (23 pages). |
International Preliminary Report on Patentability, International Applicaiton No. PCT/US2018/059245, International Filing Date Nov. 5, 2018, dated Nov. 26, 2020, 24 pages. |
Number | Date | Country | |
---|---|---|---|
20190353725 A1 | Nov 2019 | US |
Number | Date | Country | |
---|---|---|---|
62677546 | May 2018 | US | |
62672525 | May 2018 | US |