The retentate plate of the present invention allows retentate to be conveniently collected at the end of a single-pass tangential flow filtration (TFF) process. Optional handles allow for ease of set-up of the assembly but can be removed to allow for use in a multilevel assembly where the handles would interfere with the next level. Fluid exiting the assembly is sufficiently concentrated after a single pass through the series of cassettes that retentate recycle is not necessary.
The broken lines in the Figures are for illustrative purposes only, and form no part of the claimed design.