Claims
- 1. A biocompatible connective tissue repair composition, comprising:(a) demineralized bone powder, and (b) a mixture of a poly(oxyalkylene) block copolymer and water that exhibits reverse phase behavior when its temperature is increased from ambient to body temperature.
- 2. The composition of claim 1, wherein the poly(oxyalkylene) block copolymer is PLURONIC™ F127.
- 3. The composition of claim 1, wherein the mixture of poly(oxyalkylene) block copolymer and water is 25 percent weight poly(oxyalkylene) block copolymer and 75 percent weight water.
- 4. The composition of claim 1, wherein the composition is 30 percent weight demineralized bone powder and 70 percent weight poly(oxyalkylene) block copolymer and water.
- 5. The composition of claim 1, wherein the composition is 50 percent weight demineralized bone powder and 50 percent weight poly(oxyalkylene) block copolymer and water.
- 6. The composition of claim 1, wherein the demineralized bone powder is xenogeneic, allogeneic or autogenic.
- 7. The composition of claim 1, wherein the demineralized bone powder is xenogenic and from a porcine or bovine source.
- 8. A method to facilitate the development of bone tissue comprising:placing a biocompatible connective tissue repair composition at a bone defect site, wherein the biocompatible connective tissue repair composition comprises: (a) demineralized bone powder, and (b) a mixture of a poly(oxyalkylene) block copolymer and water that exhibits reverse phase behavior when its temperature is increased from ambient to body temperature.
Parent Case Info
This is a continuation of U.S. application Ser. No. 08/922,068, filed Sep. 2, 1997, now U.S. Pat. No. 6,3 09,659.
US Referenced Citations (13)
Foreign Referenced Citations (4)
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Date |
Country |
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Jul 1993 |
EP |
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Dec 1998 |
EP |
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May 1995 |
WO |
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Continuations (1)
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Number |
Date |
Country |
Parent |
08/922068 |
Sep 1997 |
US |
Child |
09/939898 |
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US |