RI-Center for Clinical and Translational Science

Information

  • Research Project
  • 10413517
  • ApplicationId
    10413517
  • Core Project Number
    U54GM115677
  • Full Project Number
    3U54GM115677-06S2
  • Serial Number
    115677
  • FOA Number
    PA-20-135
  • Sub Project Id
  • Project Start Date
    9/10/2021 - 2 years ago
  • Project End Date
    9/9/2023 - 8 months ago
  • Program Officer Name
    SAWAKI-ADAMS, LUMY
  • Budget Start Date
    9/10/2021 - 2 years ago
  • Budget End Date
    9/9/2022 - a year ago
  • Fiscal Year
    2021
  • Support Year
    06
  • Suffix
    S2
  • Award Notice Date
    9/13/2021 - 2 years ago
Organizations

RI-Center for Clinical and Translational Science

SUMMARY Until there is widespread suppression of COVID-19, SARS-CoV-2 testing will remain an essential public health tool to monitor infection patterns and address outbreaks, especially in vulnerable populations. To date, the primary focus in public health has been on reduction of COVID-19 cases in the adult population, who experience higher mortality and complications compared to the pediatric population. Nonetheless, it has been noted that COVID-19 is impacting the health, safety, and well-being of children and their caregivers. Furthermore, there are limited reports on SARS-CoV-2 testing or COVID-19 vaccinations among children and youth with special healthcare needs or their caregivers. In collaboration with community partners, this RADx-UP Phase II project will enhance a statewide system to monitor COVID-19 testing and vaccination patterns to guide improvements in access to testing and vaccine uptake among high-risk pediatric populations, defined as those who either live in vulnerable areas or with special healthcare needs. This RADx-UP Phase II project will build on our previous work to leverage the unique infrastructure of CurrentCare, the Health Information Exchange (HIE) in Rhode Island (RI), which connects data across the entire RI healthcare ecosystem, to obtain clinical data for most people receiving care in RI including SARS-CoV-2 test results and vaccinations. A major objective of this project is to quantify the impact of vaccination on vulnerable populations, focused on children, in near real-time. We are uniquely positioned to build on our explanatory sequential mixed methods design to combine HIE quantitative data with focus group and interview data (from both community members and providers in community health clinics) to further address challenges with testing and vaccination. The specific aims of this project are to: (1) Identify vaccination rates relative to COVID-19 positivity rates for high-risk pediatric populations; (2) Determine barriers to SARS-CoV-2 testing and community hesitancy to COVID-19 vaccination; and (3) Implement community-based approaches to increase testing and vaccination rates for high-risk children. In accomplishing these aims, our approach is designed around community health teams, who will facilitate the improvement of SARS-CoV-2 diagnostic testing and work with community members to understand and address vaccine hesitancy. Community health teams are widely accepted lay heath educators who have demonstrated their effectiveness in addressing community health needs. We will develop and integrate culturally congruent tools to support understanding of vaccination and possible side effects, promote conversations that help individuals move to vaccine acceptance, help with scheduling of subsequent vaccination doses, as well as continue support for access to testing and post-testing guidance. This RADx-UP Phase II project will expand the community-based infrastructure that we have developed in Phase I for enabling structured, longitudinal relationships with underserved patient populations.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    U54
  • Administering IC
    GM
  • Application Type
    3
  • Direct Cost Amount
    868787
  • Indirect Cost Amount
    222423
  • Total Cost
    1091210
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    859
  • Ed Inst. Type
    SCHOOLS OF MEDICINE
  • Funding ICs
    OD:1091210\
  • Funding Mechanism
    RESEARCH CENTERS
  • Study Section
    ZMD1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    BROWN UNIVERSITY
  • Organization Department
    PEDIATRICS
  • Organization DUNS
    001785542
  • Organization City
    PROVIDENCE
  • Organization State
    RI
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    029129002
  • Organization District
    UNITED STATES