The present invention relates generally to the field of radiographic imaging and more particularly to methods for detecting and enhancing rib features from a radiographic image.
The chest x-ray is useful for detecting a number of patient conditions and for imaging a range of skeletal and organ structures. Conventional radiographic images of the chest are useful for detection of lung nodules and other features that indicate lung cancer, other pathologic structures and other life-threatening conditions. In clinical applications such as in the Intensive Care Unit (ICU), chest x-rays can have particular value for indicating pneumothorax as well as for tube/line positioning, and other clinical conditions. To view the lung fields more clearly and allow accurate analysis of a patient's condition, it is useful to suppress the rib cage and related features in the chest x-ray, without losing detail of the lung tissue or other features within the chest cavity.
A different set of considerations applies for trauma patients, particularly with pediatric cases. With very young children, chest and other x-rays can provide the only practical method for identifying and assessing trauma, such as from accidents or mishandling of the child, including child abuse cases such as shaken-baby syndrome and the like. In such cases, enhancement of rib and other bone structures can be of particular value for identifying rib fractures and related bone damage. Utilities that help to provide a more accurate diagnosis and assessment of rib trauma and injury can help to increase staff confidence as to whether or not intervention is required as well as providing evidence in abuse cases. In addition, proper levels of enhancement can help to reduce the need for retakes and consequent added radiation exposure to the patient.
Conventional chest x-ray enhancement processing identifies the enclosed lung field content and suppresses surrounding rib content that obstructs image content of the lung tissue. For trauma identification and assessment, however, somewhat a reverse of this processing approach is needed. That is, the full rib cage, particularly posterior regions, must be identified and enhanced to allow better visibility of fractures and related conditions. This includes portions of the skeletal structure that lie outside the lung area or the area typically associated with a lung mask. It can be appreciated that the problems of rib identification and segmentation can be fairly complex due to the need to identify the full extent of the rib cage and related skeletal structure within and outside the lung regions, including areas over the heart region, subdiaphragmatic regions, and including bony and connective cartilaginous structures that link the ribs to the spine.
It can be appreciated that there is a need for methods that detect and enhance rib and other bone content in radiological images.
Embodiments of the present invention address the need for improved processing of rib and related bone content in radiography images. Advantageously, enhancement processing for ribs can be performed without noticeable impact on other portions of the x-ray image.
According to one aspect of the invention, there is provided a method for radiographic imaging, comprising: obtaining a radiographic image of a patient's chest and processing the obtained image to generate a default radiographic image and a bone-enhanced image; detecting at least a portion of one or more ribs within the default radiographic image; generating a rib mask according to the at least the detected portion of the one or more ribs; applying the rib mask to the bone-enhanced image to define masked enhanced image content that includes the detected at least the portion of one or more ribs; and generating and displaying a composite image that combines the masked enhanced image content with the default radiographic image.
These objects are given only by way of illustrative example, and such objects may be exemplary of one or more embodiments of the invention. Other desirable objectives and advantages inherently achieved by the disclosed invention may occur or become apparent to those skilled in the art. The invention is defined by the appended claims.
The foregoing and other objects, features, and advantages of the invention will be apparent from the following more particular description of the embodiments of the invention, as illustrated in the accompanying drawings. The elements of the drawings are not necessarily to scale relative to each other.
Priority is claimed from U.S. Ser. No. 61/837,325, filed as a provisional patent application on Jun. 20, 2013, entitled “RIB ENHANCEMENT IN RADIOGRAPHIC IMAGES”, in the names of LaPietra et al. and which is incorporated herein by reference in its entirety.
The following is a detailed description of the preferred embodiments of the invention, reference being made to the drawings in which the same reference numerals identify the same elements of structure in each of the several figures.
Where they are used, the terms “first”, “second”, “third”, and so on, do not necessarily denote any ordinal or priority relation, but may be used for more clearly distinguishing one element from another.
Conventional rib detection algorithms are typically directed to identifying and suppressing rib content in order to allow improved visibility of lung tissue within the radiographic image. Because of this, conventional imaging methods typically begin by identifying the lung region with a lung mask, then ignore areas outside the lung region in rib detection and other subsequent image processing. In contrast to the conventional approach, embodiments of the present invention are directed to providing enhanced images that show the full rib structure, including connective structures between posterior portions of the rib and spine.
In contrast to the conventional rib suppression presentation shown in
Following default processing step 30 in the
According to the sequence shown in
The anatomy mask 32 is applied to the processed image. Given the constrained image area defined by anatomy mask 32, the
Continuing with the sequence of
A false positive removal step 60 then helps to remove false positives from processing. Position, shape information, and gradient data are used, for example, to help eliminate false positives. Processing in steps 50, 52, 54, and 60 provides for classifying pixels into one or more of multiple ribs, by using some amount of prior knowledge of rib structures, such as shape, position, and general edge direction, and by applying morphological filtering. Among characteristics that have been found to be particularly useful for rib classification are rib width and position, including percentage of pixels initially determined to be part of a rib structure. Other features could similarly be extracted and used for false-positive removal. Rib labeling in labeling step 50 alternately calculates a medial axis for one or more ribs to generate a skeletal image for validating rib detection and for subsequent processing including rib modeling for retrieving missing or missed labeled ribs or portions of ribs. The skeletal image has medial axis information and, optionally, other anatomical data relevant to rib location.
Characteristics such as gradient orientation and shape for the labeled rib content can then be used for subsequent processing in a rib edge segmentation step 62. In rib edge segmentation step 62, edge portions of the ribs are identified, and this identification is refined using iterative processing. Guided growth processing may alternately be used to enhance rib edge detection. A cross-rib profiling step 68, by considering image content in a direction that is substantially orthogonal to the medial axis for a rib, then generates a cross-rib profile that provides values for rib compensation along the detected ribs. As a result of the processing in
As the
Various rules are applied as part of rib detection and are helpful in determining whether or not a selected feature is rib or non-rib material. For example, a generally piecewise parallel relationship of medial lines is expected, with some variability allowable over the extent of the rib structure. Some amount of curvature with respect to medial lines or rib edges is anticipated. Connective tissues near the spine can be readily distinguished once rib structures are identified and image processing can locate and highlight these structures. For rib growth, it can be helpful to begin with rib structure that corresponds to a lung mask, thus taking advantage of existing work that is done for rib suppression, such as that described in U.S. 2013/0108135 entitled “RIB SUPPRESSION IN RADIOGRAPHIC IMAGES” by Huo, for example. Additional growth beyond the lung mask is then expected and spatial relationships should fall within certain well-defined limits.
It is noted that rib detection can alternately precede default processing step 30. In an alternate embodiment of the present invention, anatomy mask 32 is generated from the unprocessed image data, and rib detection then applied to this unprocessed data. Default processing is applied at a later stage of the detection process in order to enhance the rib content separately from the balance of the image. It can be appreciated that other changes to the order of steps shown in
The logic flow diagram of
Continuing with the sequence of
Still referring to
Alternative approaches for rib mask generation include selection of a model rib mask from a library of multiple model rib masks. Selection criteria can include size and weight of the patient, view and perspective angle of the obtained image, image detector type, and other factors. Subsequent image processing, similar to that described with respect to
Multi-spectral or dual-energy imaging provides yet another alternative for either or both rib detection and mask generation step 36 and enhanced processing step 40 (
Profile 71 is generated using known characteristics of the rib in the chest x-ray. One method for providing rib profile 71 is to apply a low-pass filter (LPF) to the chest image and use the results of this processing to provide a cross-rib profile; this method is known to those skilled in image processing and analysis. An alternate method employs a model to provide an initial approximation or starting point for developing the rib profile. Using information from the model also enables rib profile information to be identified and extracted from the image itself. Whatever method is used, the usefulness of the rib profile depends, in large part, upon accurate detection of rib edges. The rib profile can be used, for example, to verify that rib structures have been correctly identified.
Returning to the workflow sequence shown in
An enhanced processing step 40 (
Referring to the sequence of steps in
The example in the sequence of
As shown in
Embodiments of the present invention thus help to provide accurate detection of rib edges and to allow improved visibility of rib and related fractures. Because the same image is processed in different ways, registration of image content between images is straightforward and can be performed with simple replacement of pixels.
Multi-spectral or dual-energy imaging provides yet another alternative for either or both rib detection step 36 and enhanced processing step 40 (
Consistent with one embodiment, the apparatus utilizes a computer program with stored instructions that perform on image data that is accessed from an electronic memory. As can be appreciated by those skilled in the image processing arts, a computer program of an embodiment of the present invention can be utilized by a suitable, general-purpose computer system, such as a personal computer or workstation. However, many other types of computer systems can be used to execute the computer program of the present invention, including an arrangement of networked processors, for example. The computer program for performing the method of the present invention may be stored in a computer readable storage medium. This medium may comprise, for example; magnetic storage media such as a magnetic disk such as a hard drive or removable device or magnetic tape; optical storage media such as an optical disc, optical tape, or machine readable optical encoding; solid state electronic storage devices such as random access memory (RAM), or read only memory (ROM); or any other physical device or medium employed to store a computer program. The computer program for performing the method of the present invention may also be stored on computer readable storage medium that is connected to the image processor by way of the internet or other network or communication medium. Those skilled in the art will further readily recognize that the equivalent of such a computer program product may also be constructed in hardware.
It is noted that the term “memory”, equivalent to “computer-accessible memory” in the context of the present disclosure, can refer to any type of temporary or more enduring data storage workspace used for storing and operating upon image data and accessible to a computer system, including a database, for example. The memory could be non-volatile, using, for example, a long-term storage medium such as magnetic or optical storage. Alternately, the memory could be of a more volatile nature, using an electronic circuit, such as random-access memory (RAM) that is used as a temporary buffer or workspace by a microprocessor or other control logic processor device. Display data, for example, is typically stored in a temporary storage buffer that is directly associated with a display device and is periodically refreshed as needed in order to provide displayed data. This temporary storage buffer can also be considered to be a memory, as the term is used in the present disclosure. Memory is also used as the data workspace for executing and storing intermediate and final results of calculations and other processing. Computer-accessible memory can be volatile, non-volatile, or a hybrid combination of volatile and non-volatile types.
It will be understood that the computer program product of the present invention may make use of various image manipulation algorithms and processes that are well known. It will be further understood that the computer program product embodiment of the present invention may embody algorithms and processes not specifically shown or described herein that are useful for implementation. Such algorithms and processes may include conventional utilities that are within the ordinary skill of the image processing arts. Additional aspects of such algorithms and systems, and hardware and/or software for producing and otherwise processing the images or co-operating with the computer program product of the present invention, are not specifically shown or described herein and may be selected from such algorithms, systems, hardware, components and elements known in the art.
It is noted that there can be any of a number of methods used for image processing functions such as segmentation of ribs from other tissue in the chest x-ray image or for filtering portions of the image content.
The invention has been described in detail with particular reference to a presently preferred embodiment, but it will be understood that variations and modifications can be effected within the spirit and scope of the invention. The presently disclosed embodiments are therefore considered in all respects to be illustrative and not restrictive. The scope of the invention is indicated by the appended claims, and all changes that come within the meaning and range of equivalents thereof are intended to be embraced therein.
Priority is claimed from U.S. Ser. No. 61/837,325, provisionally filed on Jun. 20, 2013, entitled “RIB ENHANCEMENT IN RADIOGRAPHIC IMAGES”, in the names of LaPietra et al., and which is incorporated herein by reference in its entirety.
Number | Name | Date | Kind |
---|---|---|---|
7085407 | Ozaki | Aug 2006 | B2 |
20070019852 | Schildkraut et al. | Jan 2007 | A1 |
20090060366 | Worrell | Mar 2009 | A1 |
20090060372 | Maton | Mar 2009 | A1 |
20090190818 | Huo | Jul 2009 | A1 |
20090214099 | Merlet | Aug 2009 | A1 |
20090290779 | Knapp et al. | Nov 2009 | A1 |
20130083987 | Novak | Apr 2013 | A1 |
20130108135 | Huo | May 2013 | A1 |
20140140479 | Wang | May 2014 | A1 |
20140233820 | Wu | Aug 2014 | A1 |
20140376798 | La Pietra | Dec 2014 | A1 |
Entry |
---|
Suzuki et al., Image-Processing Technique for Suppressing Ribs in Chest Radiographs by Means of Massive Training Artificial Neural Network (MTANN), IEEE Transactions on Medical Imaging, vol. 25, No. 4, Apr. 2006, pp. 406-416. |
Vogelsang et al., “Detection and Compensation of Rib Structures in Chest Radiographs for Diagnose Assistance,” Proceedings of SPIE, 3338, pp. 774-785, Feb. 1998. |
Vogelsang et al., “Model based analysis of chest radiographs,” Proceedings of SPIE, 3979, pp. 1040-1052, 2000. |
Loog et al., Filter learning: Application to suppression of bony structures from chest radiographs, Medical Image Analysis, 10, pp. 826-840, 2006. |
Number | Date | Country | |
---|---|---|---|
20140376798 A1 | Dec 2014 | US |
Number | Date | Country | |
---|---|---|---|
61837325 | Jun 2013 | US |