The present invention relates to disinfection systems and methods. More particularly, the present invention relates to a system and a method for disinfecting a room.
With the growing need for microbiological clean environments, room disinfection is an important part of maintaining a microbiologically clean environment for a variety of purposes: manufacturing, employee safety in research environments, patient safety in hospitals, and contamination control in areas such as schools, locker rooms, child care facilities, and the like.
Cleanroom disinfection is a routine procedure in many pharmaceutical, biotech, cosmetic, and other microbiology industries. These industries are dependent on microbiologically clean areas primarily for production and R&D. Additionally, some industries are governed by regulatory bodies that impose standards for microbiological cleanliness and set requirements for regular, certified biodecontamination of certain areas. Pharmaceutical facilities have a number of areas that require regular disinfection procedures in order to provide a microbiologically clean environment. Some example biodecontamination procedures include annual shutdown biodecontamination, commissioning biodecontamination, decommissioning biodecontamination of areas used for pathogen work, eradication of problematic microorganisms from production lines and laboratory areas, emergency biodecontamination for accidental release or spillage of microorganisms, regular cleanroom biodecontamination, and isolator and pass-through biodecontamination.
The present invention relates to a method for disinfecting a room. A disinfecting fog is generated in an enclosure including a first air inlet, a second air inlet, and an air dispersion outlet having a fan configured to draw air into the enclosure through the first and second air inlets and to force air out of the enclosure. The enclosure further includes a filter assembly disposed relative to the second air inlet such that air that flows between the exterior and interior of the enclosure through the second air inlet passes through the filter assembly. An air intake control assembly is actuated to open the first air inlet, and the fan is activated to draw air through the first air inlet and out of the air dispersion outlet to disperse the fog into the room. The air intake control assembly is then actuated to close the first air inlet to draw the fog from the room through the second air inlet and the filter assembly. After the fog has been removed from the room, the fan is deactivated.
While multiple embodiments are disclosed, still other embodiments of the present invention will become apparent to those skilled in the art from the following detailed description, which shows and describes illustrative embodiments of the invention. Accordingly, the drawings and detailed description are to be regarded as illustrative in nature and not restrictive.
While the invention is amenable to various modifications and alternative forms, specific embodiments have been shown by way of example in the drawings and are described in detail below. The intention, however, is not to limit the invention to the particular embodiments described. On the contrary, the invention is intended to cover all modifications, equivalents, and alternatives falling within the scope of the invention as defined by the appended claims.
The air dispersion outlet 16 includes a fan 23 that, when activated, draws air through either of side air inlets 20 and bottom air inlet 22 into the interior of the housing 12. The fan 23 also draws air from the interior of the housing 12 through the air dispersion outlet 16 and forces the air through the air dispersion assembly 18. The air dispersion assembly 18 is configured to disperse or spread the air throughout the room to be disinfected. In some embodiments, the air dispersion assembly 18 comprises a plurality of parallel panels that are angled with respect to the top of the housing 12. In other embodiments, the air dispersion assembly 18 comprises an air diffuser mounted to the fan 23.
The side air inlets 20 are disposed on the four sides that connect the top and bottom of the housing 12 in the embodiment shown. In alternative configurations, the side air inlets 20 may be provided on fewer than four sides of the housing 12. The side air inlets 20 are configured to allow air to flow between the exterior and interior of the housing 12. The shape and size of the side air inlets 20 may be designed to control the rate at which the air flows between the exterior and interior of the housing 12. In the embodiment shown, a filter 24 is arranged relative to each of the side air inlets 20 such that air drawn through the side air inlets 20 passes through the filters 24. Filter covers 26 secured to the outside of the housing 12 cover the filters 24 to protect the filters 24 from damage during transportation of the system 10. Filter doors 28 at the top of the housing 12 provide access to slots that retain the filters 24 to, for example, allow replacement of the filters 24. In alternative embodiments, the system 10 includes one or more air outlets with a filter arranged relative thereto.
The bottom air inlet 22 is disposed on the side of the housing 12 that faces the floor or ground in the embodiment shown. Alternatively, one or more air inlets that perform functions similar to bottom air inlet 22 may be located on a side and/or top of the housing 12. The bottom air inlet 22 is configured to allow air to flow between the exterior and interior of the housing 12. The positioning of the bottom air inlet 22 a distance above the floor assures that the disinfection also occurs beneath the system 10. In some embodiments, the bottom air inlet 22 does not include a filter such that air flows directly between the exterior and interior of the housing 12. The shape and size of the bottom air inlets 22 may be designed to control the rate at which the air flows between the exterior and interior of the housing 12.
A user interface 30 is provided on the top of the housing 12 to provide a means for a user to control and activate the system 10. The user interface 30 communicates with a system controller 31. In some embodiments, the user interface 30 is a button or other actuatable mechanism that allows a user to enable the system after locating the system 10 in the room to be disinfected. The user interface 30 may also include a display and/or other input devices to allow the user to select different programs and control settings of the system 10, for example. In the embodiment shown, the user interface 30 includes a touch screen, but the user interface may include other types of input devices, such as a keyboard. The user interface 30 may further include a remote control that communicates wirelessly with the system controller 31 via an antenna or other transceiver. The remote control may be configured for one-way or two-way communication with the system controller 31. In a two-way communication configuration, the remote control can display information about the status of the system 10 and the disinfection process to the user. The antenna or transceiver on the system 10 may also be configured for long-range communication, such as communication via satellite, cellular, or radio frequency signals, or over the Internet.
The system 10 also includes a chemical dispersion assembly 34. The chemical dispersion assembly 34 may include one or more chemical reservoirs 36 in the interior of the housing 12 that are configured to retain substance(s) to be dispersed into the room to be disinfected during operation of the system 10. The one or more chemical reservoirs 36 may be holding tanks or other containers, for example. In some embodiments, the chemical dispersion assembly 34 includes a disinfecting substance reservoir and an antimicrobial coating substance reservoir. In other embodiments, the disinfecting substance and the antimicrobial coating substance are combined in a single reservoir. In still other embodiments, two or more substances are retained in separate reservoirs and are combined prior to dispersing into the room (e.g., by mixing into a reservoir or by combining at the point of dispersement). The chemical dispersion assembly 34 may also retain other substances to be dispersed before, during, or after dispersement of the disinfecting substance including, but not limited to, a surfactant, an anti-corrosive agent, a buffer substance, water, a disinfectant and/or antimicrobial coating destruct chemical, and/or a fragrance. The disinfecting substance may be a room temperature (e.g., 20° C. to 25° C.) substance that can be dispersed as a fog during operation of the system 10. In other embodiments, the disinfecting substance may be used at temperatures in the range of between about −40° C. to 100° C. In some embodiments, the disinfecting substance includes peracetic acid (PAA), peracitric acid, hydrogen peroxide (H2O2), hospital grade disinfectants, and/or antimicrobial solution.
In order to prepare the disinfecting substance for dispersion into the interior of the housing 12, the chemical dispersion assembly 34 may include one or more appropriate nozzles 38 or other components in fluid communication with the chemical reservoirs 36. The chemical dispersion assembly 34 may also include a dispersion system fluidly connected between the chemical reservoirs 36 and the nozzles 38 to force the substances from the reservoirs 36 through the nozzles 38. In the embodiment shown, the dispersion system includes a pump 42, an air pressure regulator 44, and an air compressor 46. The chemical dispersion assembly 34 may also include a drain 48 to drain substances from the reservoirs 36.
In some embodiments, the one or more nozzles 38 include atomizing nozzles that are configured to transform the disinfecting substance at the input of the one or more nozzles 38 to a fog at the output of the one or more nozzles 38. In some embodiments, the one or more nozzles 38 are disposed on the top of the housing 12 relative to the air dispersion outlet 16 such that the generated fog impinges on the air flow from the air dispersion outlet 16. In other embodiments, one or more nozzles 38 are disposed in the interior of the housing 12. In further embodiments, one or more nozzles 38 are disposed on other external sides of the housing 12.
To produce the fog, the atomizing nozzle 38 may generate fine droplets of the disinfecting substance. In one embodiment, the droplets of disinfecting substance generated by the nozzle 38 average less than about 10 μm. Although larger droplets can be employed, droplets of this size allow for even dispersion and avoid excessive condensation, corrosion, and surface wetting issues in the interior of the housing 12 and the room being disinfected. In addition, some amount of the small droplets can evaporate such that the vapor portion of the fog penetrates less accessible areas. It will be appreciated that the droplet size and the amount of surfactant dispersed can be selected to provide the desired level of surface wetting in the room. The droplet size can be controlled by changing the pressure by which the disinfecting substance is forced through the nozzle 38, the air pressure that forces the disinfecting substance through the nozzle 38 (as controlled by the dispersion system), and/or by changing the size of the nozzle 38. The selection of droplet size may be based on the ambient conditions of the room to be disinfected (e.g., temperature, humidity, etc.) and the desired level of coverage in the room with the disinfecting substance and/or antimicrobial coating substance. One exemplary nozzle 38 that may be suitable for use in the chemical dispersion assembly 34 is a nozzle such as that used in the Minncare Dry Fog® or Mini Dry Fog systems, sold by Mar Cor Purification, Shippack, Pa. Another example nozzle that may be suitable for use in the chemical dispersion assembly 34 is a spray nozzle assembly including Spraying Systems Co. product numbers 1/4J-316SS, SU1A-316SS, and 46138-16-316SS, sold by Spraying Systems Co., Wheaton, Ill.
A bottom inlet cover assembly 50 is disposed between the bottom air inlet 22 and the interior of the housing 12. In some embodiments, the bottom inlet cover assembly 50 includes a plurality of parallel rotatable louvers 52.
The bottom inlet cover assembly 50 is disposed between the bottom air inlet 22 and the interior of the housing 12, and is configured to control the air that flows through the bottom air inlet 22. As discussed above, in some embodiments, the bottom inlet cover assembly 50 includes a plurality of parallel rotatable louvers 52. The system controller 31 may be configured to rotate each of the louvers 52 about its longitudinal axis to actuate the bottom inlet cover assembly 50 between its open and closed states. In alternative embodiments, the bottom inlet cover assembly 50 has other configurations that provide controllable air flow through the bottom air inlet 22. For example, the bottom inlet cover assembly 50 may comprise trapdoor-like assemblies sized to cover the air inlet 22.
The side inlet cover assembly 72 is disposed between the side air inlets 20 and the interior of the housing 12. The side inlet cover assembly 72 is configured to control the air that flows through the side air inlets 20. The side inlet cover assembly 72 and bottom inlet cover assembly 50 are independently controllable and actuatable. In some embodiments, the side inlet cover assembly 72 and bottom inlet cover assembly 50 each include a plurality of parallel rotatable louvers. The system controller 31 may be configured to rotate each of the louvers about its longitudinal axis to actuate the inlet cover assemblies 50, 72 between their open and closed states. In alternative embodiments, the side inlet cover assembly 72 and/or the bottom inlet cover assembly 50 have other configurations that provide controllable air flow through the side air inlets 20 and bottom air inlet 22, respectively. For example, the side inlet cover assembly 72 and/or bottom inlet cover assembly 50 may comprise trapdoor-like assemblies sized to cover the air inlets 20, 22.
The system 10 is prepared for operation by filling the chemical reservoirs of the chemical dispersion assembly 34 with the desired substances and transporting the system 10 to the desired location. For example, as discussed above, one chemical reservoir 36 may be filled with a disinfecting substance and another chemical reservoir 36 may be filled with a longer duration antimicrobial coating substance, the two substances may be combined in a single reservoir 36, or the substances may be mixed just prior to or during dispersement. A surfactant may be combined with the disinfecting substance or added to one of the chemical reservoirs 36. The user interface 30 may then be used to initiate operation of the system 10 to begin the disinfection process. In some embodiments, a button is pressed on the user interface 30, and the system controller 31 waits a predetermined period of time before starting the process to allow the user to exit the room. For example, in embodiments of the system 10 including a remote control interface, the disinfection process may be initiated by pressing one or more buttons on the remote control 61. In alternative embodiments, the sensor module 62 may include one or more status sensors, such as motion, heat sources, and/or other sensors, in communication with the system controller 31 that prevents the system 10 from initiating while the sensors detect activity in the room.
The sensor module 62 may also include one or more ambient condition sensors that sense the conditions of the room to be disinfected prior to the disinfection process. For example, the efficacy of the disinfecting substance and/or the antimicrobial coating substance (the latter discussed in more detail below) may be affected by the temperature and/or humidity of the room. Thus, in some embodiments, the sensor module 62 includes temperature and/or humidity sensors that provide signals to the system controller 31 relating to the temperature and humidity of the room. If the sensor module 62 senses conditions that are not suitable or ideal for disinfection of the room, the system controller 31 may prevent the system from initiating the process, and may indicate which conditions are less than satisfactory on the user interface 30.
The system 10 may also include an environment control system 64 that allows the system 10 to adjust the room conditions to a satisfactory state before or during the disinfection process. For example, the environment control system 64 may include integrated heaters that are activated by the system controller if the room is too cold to disperse the disinfecting substance and/or the antimicrobial coating substance. The environment control system 64 may also include a humidifier or dehumidifier that may be activated by the system controller 31 to adjust the humidity to satisfactory levels prior to initiating the process or during the process. Alternatively, the environment control system 64 may be configured to mix water with the disinfecting substance to increase the humidity of the room while dispersing the disinfecting substance.
The system controller 31 may delay activation of the disinfecting process until the environment control system 64 adjusts ambient conditions in the room to threshold ambient conditions. The threshold ambient conditions, which may be programmed in the system controller 31, may be set to increase the efficacy of the disinfecting substance and/or antimicrobial coating substance.
If the system controller 31 determines that ambient conditions are satisfactory based on signals from the sensor module 62, the system 10 may then begin the process of disinfecting the room. In the control system 60, the bottom inlet cover assembly 50 is opened, which causes most air to flow into the housing 12 via the bottom air inlet 22 due to the presence of the filters 24 at the side air inlets 20. That is, the air flow through the side inlets 20 is impeded by the filters 24, and thus most air is drawn into the housing 12 through the bottom air inlet 22. The fan 23 is then activated to begin pulling air through the housing 12 via the bottom air inlet 22, as illustrated in
In the control system 70 in
The system 10 then disperses the disinfecting substance into the room to be disinfected. The system controller 31 commands the chemical dispersion assembly 34 to begin dispensing the disinfecting substance relative to the air dispersion assembly 16. For example, in embodiments in which the disinfecting substance is transformed into a fog as described above, the chemical dispersion assembly 34 forces the disinfecting substance through one or more atomizing nozzles 38 to generate the fog near the fan 23. As the fog is generated, the fog impinges the air flow from the air dispersion outlet 16 for dispersion into the room to be disinfected. The fan 23 continues to operate while the chemical dispersion assembly 34 disperses the fog for a predetermined time. This predetermined time may be based on the size of the room to be disinfected, for example. In some embodiments, the amount of time that the chemical dispersion assembly 34 disperses the disinfecting substance while the fan 23 is operating is based on a program selected via the user interface 30. The system 10 may also include one or more sensors that monitor the concentration of the disinfecting substance in the room and alert the system controller 31 when the programmed concentration is reached.
In some embodiments, the fog is then held in the room for a predetermined time. During this hold time, the fan 23 may continue to run with the bottom inlet cover 48 open to circulate the fog through the room. The predetermined time may be programmed into the system controller 31 and may be based on the size of the room being disinfected. The time may also be determined based on room conditions such as temperature, fog concentration, and humidity that are sensed by the sensor module 62 before or during the disinfection process. This is because the temperature, concentration, and/or humidity can affect the time it takes to reach the desired level of decontamination.
When dispersion of the fog is completed, the system controller 31 closes the bottom inlet cover assembly 50. In the control system 70, the system controller 31 also opens the side inlet cover assembly 72. In both control systems 60 and 70, this arrangement prevents air flow through the bottom air inlet 22 and causes air from the room to be drawn through the filters 24 and the side air inlets 20 into the housing 12, as illustrated in
After passing through the filters 24, the air in the interior of the housing 12 is substantially free of the disinfecting substance. This air is redistributed into the room through the air dispersion outlet 16 by the fan 23. This process reduces the concentration of the disinfecting substance in the room. The fan 23 continues to circulate the air in the room through the filters 24 for a predetermined time to remove substantially all of the disinfecting substance from the room. The predetermined time may be based on the size of the room, and/or may be based on a program selected via the user interface 30.
As discussed above, the sensor module 62 may include one or more sensors that provide signals to the system controller 31 related to the concentration of the disinfecting substance in the room. In this case, the system controller 31 can continue to run the fan 23 until the concentration of the disinfecting substance gets to suitable levels. The system 10 can also provide visual and/or audible indicators (e.g., via the user interface 30 or the remote control 61) during vapor destruction until the disinfecting substance concentration reaches the suitable levels.
During or following dispersion of the disinfecting substance, the system 10 may optionally disperse an antimicrobial coating substance that coats surfaces in the room. In addition, the system controller 31 may operate the environment control system 64 to adjust room conditions if preferred ambient conditions are different for the antimicrobial coating. The antimicrobial coating remains on the surfaces so as to extend the time that the room remains clean after the disinfection process. One exemplary substance suitable for use as an antimicrobial coating is disclosed in U.S. Pat. No. 4,259,103, entitled “Method of Reducing the Number of Microorganisms in a Media and a Method of Preservation,” which is incorporated herein by reference in its entirety.
To distribute the antimicrobial coating substance, the system controller 31 opens the bottom inlet cover assembly 50 to allow air to flow through the bottom air inlet 22, as illustrated in
In some embodiments, the antimicrobial coating substance is then held in the room for a predetermined time to allow the antimicrobial coating substance to coat the surfaces of the room. During this hold time, the fan 23 may continue to run with the bottom inlet cover assembly 50 open to circulate the fog through the room. Alternatively, the fan 23 may be disabled during the hold time. The predetermined time may be programmed into the system controller 31 and may be based on the size of the room being disinfected. The time may also be determined based on room conditions such as temperature and humidity that are sensed before or during the disinfection process. This is because the temperature and/or humidity can affect the ability of the antimicrobial substance to bond to surfaces in the room.
After dispersion of the antimicrobial coating substance, the system controller 31 may close the bottom inlet cover assembly 50 (and, in the control system 70, open the side inlet cover assembly 72) to draw air from the room through the filters 24 and the side air inlets 20 into the housing 12. This removes the antimicrobial coating substance from the air in the room. In an alternative embodiment, the system 10 includes different filters or different substances within the same filters for the destruction of the disinfecting substance and antimicrobial substance. When the antimicrobial substance has been drawn from the room, the disinfection process ends and the system controller 31 disables components of the system 10, including the chemical dispersion system 44 and the fan 23. The system controller 31 may also open or close the bottom inlet cover assembly 50 (and, in the control system 70, open or close the side inlet cover assembly 72) at the end of the cycle. In some embodiments, the system 10 further provides an audible and/or visual signal that indicates that the system 10 has completed the disinfecting cycle.
In summary, the present invention relates to a system for disinfecting a room including an enclosure having first and second air inlets, and an air intake control assembly configured for selectable control of air flow between an exterior and an interior of the enclosure through the first and second air inlets. A filter assembly is disposed relative to the second air inlet such that air that flows between the exterior and interior of the enclosure through the second air inlet passes through the filter assembly. An air dispersion outlet including a fan is configured to draw air into the enclosure through the first and second air inlets and to force air out of the enclosure. A chemical dispersion assembly is configured to generate a disinfecting fog relative to the air dispersion outlet. A system controller is configured to open the first air inlet and activate the fan to disperse the disinfecting fog into the room, and subsequently close the first air inlet to draw the disinfecting fog from the room and through the filter assembly. The system as described is capable of disinfecting substantially all surfaces in the room quickly and automatically.
Various modifications and additions can be made to the exemplary embodiments discussed without departing from the scope of the present invention. While the embodiments described above refer to particular features, the scope of this invention also includes embodiments having different combinations of features and embodiments that do not include all of the described features. Accordingly, the scope of the present invention is intended to embrace all such alternatives, modifications, and variations as fall within the scope of the claims, together with all equivalents thereof. For example, while the system 10 has been described as a portable box-like assembly, it will be appreciated that other configurations are also possible, such as ceiling mounted, door mounted, or wall mounted configurations.
This application is a divisional application of U.S. application Ser. No. 12/904,415, filed Oct. 14, 2010 which claims priority to Provisional Application No. 61/252,011, filed Oct. 15, 2009 and Provisional Application No. 61/260,466, filed Nov. 12, 2009, which are incorporated herein by reference in their entireties.
Number | Name | Date | Kind |
---|---|---|---|
1062404 | Kiefer | May 1913 | A |
1114880 | Hall | Oct 1914 | A |
1837264 | Hackley | Dec 1931 | A |
2965936 | Kaye | Jun 1957 | A |
2836570 | Peers | May 1958 | A |
3114599 | Fanning | Dec 1963 | A |
3436173 | Power | Apr 1969 | A |
3498742 | Long | Mar 1970 | A |
3547576 | Sheikh | Dec 1970 | A |
3816074 | Decupper | Jun 1974 | A |
3936270 | Gunther | Feb 1976 | A |
3958935 | Kowol | May 1976 | A |
4064062 | Yurko | Dec 1977 | A |
4119400 | Kurz | Oct 1978 | A |
4169123 | Moore et al. | Sep 1979 | A |
4169124 | Forstrom et al. | Sep 1979 | A |
4230663 | Forstrom et al. | Oct 1980 | A |
4241010 | Baran | Dec 1980 | A |
4241020 | Grantham | Dec 1980 | A |
4249265 | Coester | Feb 1981 | A |
4259103 | Malek et al. | Mar 1981 | A |
4270658 | Schuster | Jun 1981 | A |
4294804 | Baran | Oct 1981 | A |
4366125 | Kodera et al. | Dec 1982 | A |
4447399 | Runnells et al. | May 1984 | A |
4457892 | Young | Jul 1984 | A |
4483771 | Koch | Nov 1984 | A |
4512951 | Koubek | Apr 1985 | A |
4587264 | Jourdan-Laforte et al. | May 1986 | A |
4592896 | Runnells et al. | Jun 1986 | A |
4637916 | Hennebert et al. | Jan 1987 | A |
4643876 | Jacobs et al. | Feb 1987 | A |
4687635 | Kaehler et al. | Aug 1987 | A |
4744951 | Cummings et al. | May 1988 | A |
4756882 | Jacobs et al. | Jul 1988 | A |
4843867 | Cummings | Jul 1989 | A |
4892705 | Sternfeld et al. | Jan 1990 | A |
4904901 | Simopoulos et al. | Feb 1990 | A |
4921675 | Johnson | May 1990 | A |
4943414 | Jacobs et al. | Jul 1990 | A |
4952370 | Cummings et al. | Aug 1990 | A |
4956145 | Cummings et al. | Sep 1990 | A |
4986963 | Corcoran et al. | Jan 1991 | A |
5008079 | Wutzler et al. | Apr 1991 | A |
5258162 | Andersson et al. | Nov 1993 | A |
5340878 | Sadatoshi et al. | Aug 1994 | A |
5460962 | Kemp | Oct 1995 | A |
5482683 | Sheth et al. | Jan 1996 | A |
5508009 | Rickloff et al. | Apr 1996 | A |
5512244 | Griffiths et al. | Apr 1996 | A |
5527508 | Childers et al. | Jun 1996 | A |
5534221 | Hillebrenner et al. | Jul 1996 | A |
5556607 | Childers et al. | Sep 1996 | A |
5580530 | Kowatsch et al. | Dec 1996 | A |
5620656 | Wensky et al. | Apr 1997 | A |
5641455 | Rosenlund et al. | Jun 1997 | A |
5667753 | Jacobs et al. | Sep 1997 | A |
5674450 | Lin et al. | Oct 1997 | A |
5676837 | Jungbauer et al. | Oct 1997 | A |
5733503 | Kowatsch et al. | Mar 1998 | A |
5741460 | Jacob et al. | Apr 1998 | A |
5779973 | Edwards et al. | Jul 1998 | A |
5784934 | Izumisawa | Jul 1998 | A |
5792422 | Lin et al. | Aug 1998 | A |
5801010 | Falkowski et al. | Sep 1998 | A |
5834313 | Lin | Nov 1998 | A |
5847393 | Van Den Berg et al. | Dec 1998 | A |
5851483 | Nicolle et al. | Dec 1998 | A |
5863499 | Kralovic | Jan 1999 | A |
5869000 | DeCato | Feb 1999 | A |
5876666 | Lin et al. | Mar 1999 | A |
D408837 | Gotham et al. | Apr 1999 | S |
5902413 | Puszko et al. | May 1999 | A |
5904901 | Shimono et al. | May 1999 | A |
5906794 | Childers | May 1999 | A |
5955025 | Barrett | Sep 1999 | A |
5961921 | Addy et al. | Oct 1999 | A |
5980825 | Addy et al. | Nov 1999 | A |
6010662 | Lin et al. | Jan 2000 | A |
6030579 | Addy et al. | Feb 2000 | A |
6036918 | Kowanko | Mar 2000 | A |
6039922 | Swank et al. | Mar 2000 | A |
6041794 | Lin et al. | Mar 2000 | A |
6066294 | Lin et al. | May 2000 | A |
6094887 | Swank et al. | Aug 2000 | A |
6096265 | Mezger et al. | Aug 2000 | A |
6096266 | Duroselle | Aug 2000 | A |
6120730 | Swank et al. | Sep 2000 | A |
6135433 | Nurmi | Oct 2000 | A |
6162394 | Nicolle et al. | Dec 2000 | A |
6162395 | Kowanko | Dec 2000 | A |
6183691 | Swank et al. | Feb 2001 | B1 |
D438980 | Hehenberger | Mar 2001 | S |
6234310 | Goldhaber | May 2001 | B1 |
6269680 | Prieve et al. | Aug 2001 | B1 |
6286527 | Stanley | Sep 2001 | B1 |
6312645 | Lin et al. | Nov 2001 | B1 |
6312646 | Kowanko | Nov 2001 | B2 |
6354312 | Lin et al. | Mar 2002 | B1 |
6365102 | Wu et al. | Apr 2002 | B1 |
6365103 | Fournier | Apr 2002 | B1 |
6391260 | Davis et al. | May 2002 | B1 |
6406666 | Cicha et al. | Jun 2002 | B1 |
6439246 | Stanley | Aug 2002 | B2 |
6451254 | Wang et al. | Sep 2002 | B1 |
6468472 | Yu et al. | Oct 2002 | B1 |
6495100 | Lin et al. | Dec 2002 | B1 |
6528017 | Jacobs et al. | Mar 2003 | B2 |
6530399 | Nguyen et al. | Mar 2003 | B2 |
6582654 | Kral et al. | Jun 2003 | B1 |
6594971 | Addy et al. | Jul 2003 | B1 |
6596231 | Catelli et al. | Jul 2003 | B1 |
6600444 | Desjardins | Jul 2003 | B2 |
6641781 | Walta | Nov 2003 | B2 |
6673313 | Wang et al. | Jan 2004 | B2 |
6746647 | Kohler et al. | Jun 2004 | B2 |
6790410 | Metzner et al. | Sep 2004 | B2 |
6797234 | Stanley | Sep 2004 | B2 |
6884392 | Malkin et al. | Apr 2005 | B2 |
6977061 | Lin et al. | Dec 2005 | B2 |
6998582 | Maroti | Feb 2006 | B1 |
7001873 | McDonnell et al. | Feb 2006 | B2 |
7005549 | Hobson et al. | Feb 2006 | B2 |
7025932 | Martin et al. | Apr 2006 | B2 |
7146746 | Kawasaki | Dec 2006 | B2 |
7178555 | Engel et al. | Feb 2007 | B2 |
7179419 | Lin et al. | Feb 2007 | B2 |
7186371 | Watling | Mar 2007 | B1 |
7186372 | Kohler et al. | Mar 2007 | B2 |
7186374 | Zelina et al. | Mar 2007 | B2 |
7294305 | Lin et al. | Nov 2007 | B2 |
7303073 | Raynal-Olive et al. | Dec 2007 | B2 |
7307191 | Hobson et al. | Dec 2007 | B2 |
7326382 | Adiga et al. | Feb 2008 | B2 |
7434372 | Vanhamel et al. | Oct 2008 | B2 |
7449145 | Kohler et al. | Nov 2008 | B2 |
7452504 | Wu et al. | Nov 2008 | B2 |
7468159 | Lin et al. | Dec 2008 | B2 |
7491371 | Moller et al. | Feb 2009 | B2 |
7541002 | Centanni | Jun 2009 | B2 |
7556767 | Lin et al. | Jul 2009 | B2 |
7569180 | Kohler et al. | Aug 2009 | B2 |
7578969 | Mielnik et al. | Aug 2009 | B2 |
7604773 | Ekstrom et al. | Oct 2009 | B2 |
7608218 | Fryer et al. | Oct 2009 | B2 |
7611667 | Centanni | Nov 2009 | B2 |
7615187 | Helton et al. | Nov 2009 | B2 |
7622074 | Mielnik | Nov 2009 | B2 |
7651667 | McVey et al. | Jan 2010 | B2 |
7670550 | Lin et al. | Mar 2010 | B2 |
7670565 | McVey et al. | Mar 2010 | B2 |
7678339 | Wira | Mar 2010 | B2 |
7713473 | Kendall et al. | May 2010 | B2 |
7718122 | Smith et al. | May 2010 | B2 |
7803315 | McDonnell et al. | Sep 2010 | B2 |
7807100 | Choperena et al. | Oct 2010 | B2 |
7811531 | Mielnik et al. | Oct 2010 | B2 |
7850925 | Centanni et al. | Dec 2010 | B2 |
7988911 | Centanni et al. | Aug 2011 | B2 |
7988920 | Centanni et al. | Aug 2011 | B2 |
7993602 | Moriyama et al. | Aug 2011 | B2 |
8012424 | Jethrow et al. | Sep 2011 | B2 |
8025848 | McVey et al. | Sep 2011 | B2 |
8056719 | Porret et al. | Nov 2011 | B2 |
8062590 | Ricciardi et al. | Nov 2011 | B1 |
8110156 | Ricciardi et al. | Feb 2012 | B2 |
8128789 | Hirata et al. | Mar 2012 | B2 |
8133437 | Scalzo et al. | Mar 2012 | B2 |
8178357 | Trogler et al. | May 2012 | B2 |
8236240 | Childers et al. | Aug 2012 | B2 |
8298482 | Rees et al. | Oct 2012 | B2 |
8343422 | Sato et al. | Jan 2013 | B2 |
8343437 | Patel | Jan 2013 | B2 |
8357331 | McVey et al. | Jan 2013 | B2 |
8425837 | Carbone et al. | Apr 2013 | B2 |
8444919 | Erickson | May 2013 | B2 |
8821807 | Schwartz et al. | Sep 2014 | B2 |
8889081 | Schwartz et al. | Nov 2014 | B2 |
9017607 | Olson et al. | Apr 2015 | B2 |
20010000227 | Kowanko | Apr 2001 | A1 |
20010036422 | Lin et al. | Nov 2001 | A1 |
20010053333 | Messier et al. | Dec 2001 | A1 |
20020069616 | Odell et al. | Jun 2002 | A1 |
20020081228 | Hui et al. | Jun 2002 | A1 |
20020085950 | Robitaille et al. | Jul 2002 | A1 |
20020114727 | McVey et al. | Aug 2002 | A1 |
20020122744 | Hui et al. | Sep 2002 | A1 |
20020168289 | McVey | Nov 2002 | A1 |
20020187067 | Lukasik et al. | Dec 2002 | A1 |
20030017074 | Wang et al. | Jan 2003 | A1 |
20030086820 | McDonnell et al. | May 2003 | A1 |
20030124026 | Williams et al. | Jul 2003 | A1 |
20030133834 | Karle | Jul 2003 | A1 |
20030138347 | Lin | Jul 2003 | A1 |
20030190253 | Kohler et al. | Oct 2003 | A1 |
20030235511 | Jacobs et al. | Dec 2003 | A1 |
20040001776 | Fryer et al. | Jan 2004 | A1 |
20040005240 | Adiga et al. | Jan 2004 | A1 |
20040005259 | Sacca | Jan 2004 | A1 |
20040022671 | Malatesta | Feb 2004 | A1 |
20040022673 | Protic | Feb 2004 | A1 |
20040028556 | Frost et al. | Feb 2004 | A1 |
20040052679 | Root et al. | Mar 2004 | A1 |
20040081601 | Morrissey et al. | Apr 2004 | A1 |
20040162228 | Hobson et al. | Aug 2004 | A1 |
20040170527 | Jacobs et al. | Sep 2004 | A1 |
20040184950 | McVey et al. | Sep 2004 | A1 |
20050013726 | Hill et al. | Jan 2005 | A1 |
20050042130 | Lin et al. | Feb 2005 | A1 |
20050084431 | Hill et al. | Apr 2005 | A1 |
20050147527 | Brown et al. | Jul 2005 | A1 |
20050196313 | Choperena et al. | Sep 2005 | A1 |
20050252274 | Centanni | Nov 2005 | A1 |
20050260097 | Williams et al. | Nov 2005 | A1 |
20060078459 | Kohler et al. | Apr 2006 | A1 |
20060088441 | Hill | Apr 2006 | A1 |
20060099106 | Watling et al. | May 2006 | A1 |
20070003431 | Kendall et al. | Jan 2007 | A1 |
20070014691 | Lin et al. | Jan 2007 | A1 |
20070034095 | McDonnell et al. | Feb 2007 | A1 |
20070053813 | Martin | Mar 2007 | A1 |
20070092398 | McDonald | Apr 2007 | A1 |
20070098592 | Buczynski et al. | May 2007 | A1 |
20070160491 | Kohler et al. | Jul 2007 | A1 |
20070207054 | Langford | Sep 2007 | A1 |
20070253859 | Hill | Nov 2007 | A1 |
20080240981 | Berentsveig et al. | Oct 2008 | A1 |
20090209031 | Stopek | Aug 2009 | A1 |
20090324445 | Kohler et al. | Dec 2009 | A1 |
20100011823 | Dahms et al. | Jan 2010 | A1 |
20100028200 | Shiosawa | Feb 2010 | A1 |
20100034697 | Weinberger et al. | Feb 2010 | A1 |
20100034707 | Mielnik et al. | Feb 2010 | A1 |
20100143218 | Nurminen et al. | Jun 2010 | A1 |
20100196197 | Rovison, Jr. et al. | Aug 2010 | A1 |
20100226821 | Ricciardi et al. | Sep 2010 | A1 |
20100296969 | Ngo et al. | Nov 2010 | A1 |
20100297776 | Trogler et al. | Nov 2010 | A1 |
20100303671 | Bertrand | Dec 2010 | A1 |
20100316527 | McLaren et al. | Dec 2010 | A1 |
20110044851 | Centanni et al. | Feb 2011 | A1 |
20110044852 | Ryan et al. | Feb 2011 | A1 |
20110052449 | Centanni et al. | Mar 2011 | A1 |
20110076189 | McVey et al. | Mar 2011 | A1 |
20110076192 | Robitaille et al. | Mar 2011 | A1 |
20110079525 | Peck et al. | Apr 2011 | A1 |
20110091354 | Schwartz et al. | Apr 2011 | A1 |
20110135537 | Schwartz et al. | Jun 2011 | A1 |
20110165299 | Sato et al. | Jul 2011 | A1 |
20110182772 | Holt | Jul 2011 | A1 |
20120009085 | Burger | Jan 2012 | A1 |
20120189494 | Rovison, Jr. et al. | Jul 2012 | A1 |
20120219456 | Childers et al. | Aug 2012 | A1 |
20120277662 | Golkowski | Nov 2012 | A1 |
20120301356 | Olson et al. | Nov 2012 | A1 |
20130065958 | Dunn | Mar 2013 | A1 |
20130101462 | Keil | Apr 2013 | A1 |
20140369887 | Schwartz et al. | Dec 2014 | A1 |
20150202339 | Schwartz et al. | Jul 2015 | A1 |
Number | Date | Country |
---|---|---|
1141003 | Jan 1997 | CN |
1585817 | Feb 2005 | CN |
102018966 | Apr 2011 | CN |
103702689 | Apr 2014 | CN |
0302420 | Feb 1989 | EP |
0774263 | May 1997 | EP |
0923951 | Jun 1999 | EP |
1378253 | Jan 2004 | EP |
1481692 | Dec 2004 | EP |
1813220 | Aug 2007 | EP |
1473044 | Dec 2007 | EP |
1171368 | Feb 2008 | EP |
1935515 | Jun 2008 | EP |
1308173 | Dec 2008 | EP |
1110557 | Mar 2009 | EP |
2228076 | Sep 2010 | EP |
2714101 | Apr 2014 | EP |
2506884 | Feb 2015 | EP |
08126605 | May 1996 | JP |
11015570 | Jan 1999 | JP |
11137650 | May 1999 | JP |
2002508219 | Mar 2002 | JP |
2003260118 | Sep 2003 | JP |
2005143669 | Jun 2005 | JP |
2007167546 | Jul 2007 | JP |
2009513213 | Apr 2009 | JP |
2009131296 | Jun 2009 | JP |
2009268466 | Nov 2009 | JP |
WO0207788 | Jan 2002 | WO |
WO0249682 | Jun 2002 | WO |
2006013089 | Feb 2006 | WO |
WO2007008205 | Jan 2007 | WO |
WO2007049076 | May 2007 | WO |
WO2008014615 | Feb 2008 | WO |
WO2012128734 | Sep 2012 | WO |
2012173756 | Dec 2012 | WO |
Entry |
---|
“Cantel Subsidiary Receives Expanded EPO Approval for Minncare Cold Sterilant in Fogging Application”, Business Wire, Jul. 4, 2008, 1 page. |
“Vapor Liquid-/Solid System”, Retrieved from Internet electronic mail: http://blowers.chee.arizona.edu/201project/Glsys.interrelatn.pgl.HTML/, retrieved on Dec. 10, 2014, Vapor-Liquid/Solid Equilibruim, (C) 2007, 8 pages. |
European Search Report issued in EP Application No. 13152441, mailed Feb. 27, 2013, 8 pages. |
FMC Material Safety Data Sheet, Date Approved Nov. 10, 2006, 11 pages. |
International Search Report and Written Opinion issued in PCT/US2010/052622, mailed Jan. 20, 2011, 14 pages. |
International Search Report and Written Opinion issued in PCT/US2010/058885, mailed Feb. 10, 2011, 11 pages. |
International Search Report and Written Opinion issued in PCT/US2012/039160, mailed Oct. 2, 2012. |
International Standard, ISO 11140-1, 2nd Edition Jul. 15, 2005, Sterilization of Health Care Products—Chemical Indicators—Part 1: General Requirements, pp. 1-27. |
Lunger, MJ et al., “Reducing Pump-Down Time With Dry Air Venting”, 43rd Annual Technical Conference Proceedings, Denver, Apr. 15-20, 2000, 1 page. |
Minncare Dry Fog™ System: An Integral part of Modern Cleanroom Disinfection Procedures, © 2009 Mar Cor Purification, 4 pages. |
Portner, Dorothy M. et al., “Sporicidal Effect of Peracetic Acid Vapor”, Applied Microbiology, vol. 16, No. 11, Nov. 1968, pp. 1782-1785. |
Rutala, William A. et al., “New Disinfection and Sterilization Methods”, Emerging Infectious Diseases Journal, vol. 7, No. 2, Mar.-Apr. 2001, 14 pages. |
The Mini Fog System: A Modern Method to Enhance Small Space Disinfection, © 2008 Mar Cor Purification, 2 pages. |
International Preliminary Report on Patentability issued in PCT/US2012/039160, mailed Dec. 12, 2013, 7 pages. |
Number | Date | Country | |
---|---|---|---|
20150064066 A1 | Mar 2015 | US |
Number | Date | Country | |
---|---|---|---|
61252011 | Oct 2009 | US | |
61260466 | Nov 2009 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 12904415 | Oct 2010 | US |
Child | 14543554 | US |