There are no related applications.
This invention relates to rotary tablet presses and, more particularly to a removeable turret module.
Oral dosage medication is typically manufactured by directly compressing granulation on a rotary tablet press. Tooling is used on the tablet press to identify and produce specific products. The tooling consists of an upper punch, lower punch, and a die. To form a tablet, granulated powder material must be fed into a cavity formed by two punches and a die. The punches are pressed together with sufficient force to fuse the powder into a tablet.
All granulations are abrasive and due to the force at compaction, tools wear out and must be replaced. Maintaining quality tooling is essential to product consistency. Cleaning is also frequently required.
In a rotary tablet press, a turret is rotatable about a vertical axis and carries a plurality of dies. Each die has associated top and bottom punches driven by top and bottom cams to compress the granulation into a tablet. For cleaning between batches or changeover for a different tablet, product containing parts including the turret with punches and cam, feeder, tablet discharge chute, and hopper are removable as units from the tablet press.
Such rotary tablet presses are provided by various manufacturers and described, for example, in U.S. Pat. Nos. 4,988,275 and 6,676,863 and EP1050399.
Prior art removable turret press designs incorporate a single press frame for structural support of the turret and pressure roll assemblies. These designs prevent the removal of the turret, feeder, tablet discharge chute, and hopper, along with the machine base on which they are supported. These designs generally require an operator to disconnect, move and/or remove several components including removing a heavy turret and loading it onto an ancillary cart in order to change the press to a different tooling size or configuration such as bi-layer or tri-layer. These designs also constrain the tablet press to only utilize turrets having the same diameter and height dimensions. Prior art designs require cleaning and great care in transferring the equipment to a cleaning room without risk of cross contamination. Prior art presses with removable or detachable turrets incorporate mechanisms that attach to and drive the turret from beneath. This not only requires an ancillary cart but also the requirement to disconnect, move and/or remove press components and lift and load the turret.
Pending application Ser. No. 17/326,653, filed May 21, 2021, owned by Applicant herein, discloses a rotary tablet press comprising a base assembly including a press housing and a compression assembly in the press housing including pressure roll assemblies. A detachable module is removably mountable to the base assembly comprising a module base supporting a turret housing. A turret assembly is rotatably mounted in the turret housing about a vertical axis. The turret assembly comprises a plurality of die stations. The detachable module is selectively positioned at the base assembly so that the pressure roll assemblies engage the turret assembly to compress a granulation into a tablet at the die stations. A turret drive assembly comprises a turret motor and drive shaft. The drive shaft is aligned with the vertical axis and engaging the turret assembly to rotate the turret assembly.
The present invention is directed to improvements in design of a removable turret, and the removal and changeover of product contact parts.
An object of the present invention is to provide a tablet press that is more configurable and flexible for tablet manufacturers, requires less time for changeover between batches, and contains dust generated during the tableting operation to minimize exposure to the operator. This is accomplished by housing the compression roll assemblies and turret assembly in two separate and distinct support structures that can be connected to one another and operate in unison as a tablet press.
In view of this objective, the press is divided into two primary assemblies herein referred to as the machine frame and detachable turret module. The machine incorporates motorized pressure roll assemblies that may move both linearly and axially. Having linear movement, the pressure rolls are automatically moved into a position, if necessary, to allow the turret module to be detached and removed from the base assembly without interference. The movement, if necessary, allows the compression assemblies housed in the base assembly to adjust tablet thickness during operation and to be configured for various turret modules containing turrets with different physical dimensions during setup.
In accordance with one aspect of the invention, a rotary tablet press comprises a machine frame comprising a press housing and a compression assembly in the press housing including pressure roll assemblies. A connection base extends outwardly from the press housing. A detachable module is removably mountable to the base assembly comprising a module base supporting a turret housing. A turret assembly is rotatably mounted in the turret housing about a vertical axis. The turret assembly comprises a plurality of die stations. The detachable module is selectively positioned at the base assembly so that the pressure roll assemblies engage the turret assembly to compress a granulation into a tablet at the die stations. A cart is operatively secured to the module base and comprises a controllable lifting mechanism for raising and lowering the detachable module to selectively position the module base on the connection base.
In accordance with another aspect of the invention, a rotary tablet press comprises a machine frame comprising a press housing and a compression assembly in the press housing including pressure roll assemblies, and a connection base extending outwardly from a bottom end of the press housing. A detachable module is removably mountable to the press housing comprising a module base including a control housing atop a support housing and a turret housing mounted atop the control housing, a turret assembly rotatably mounted in in the turret housing about a vertical axis, the turret assembly comprising a plurality of die stations, the detachable module being selectively positioned at the press housing so that the pressure roll assemblies engage the turret assembly to compress a granulation into a tablet at the die stations. A turret drive assembly comprises a turret motor and drive shaft, the drive shaft being aligned with the vertical axis and engaging the turret assembly to rotate the turret assembly. A cart is operatively secured to the module base and comprises a controllable lifting mechanism for raising and lowering the detachable module to selectively position the module base on the connection base.
Further features will be readily apparent from the specification and from the drawings.
The present invention relates to a rotary tablet press comprising a base assembly or machine frame and detachable turret module. The machine frame incorporates motorized pressure roll assemblies and optionally a turret drive assembly. The detachable module comprises a module base, turret housing, turret, cam body, cams, feeder, tablet discharge chute, hopper, upper enclosure, and guard doors. The detachable module could also incorporate pressure roll assemblies for bilayer or trilayer applications. The turret comprises chambers arranged circumferentially to hold upper punches, lower punches, and dies. As the turret rotates, punches follow a cam track and reciprocate into and out of dies that receive granulation as they are rotated under the feeder. A tablet is formed when the punches contact the pressure rolls causing compaction of the granulation in the die.
The disclosed tablet press is more configurable and flexible for tablet manufacturers, requires less time for changeover between batches, and contains dust generated during the tableting operation to minimize exposure to the operator. This is accomplished by housing the compression roll assemblies and turret assembly in two separate and distinct support structures that can be connected to one another and operate in unison as a tablet press.
The press is divided into two primary assemblies herein referred to as the machine frame and the detachable turret module. The machine frame incorporates motorized pressure roll assemblies that may move both linearly and axially. Having linear movement, the pressure rolls are automatically moved towards or away from one another into a position, if necessary, to allow the turret module to be detached and removed from the press frame without interference. The axial movement allows the compression assemblies housed in the machine frame to adjust tablet thickness during operation and to be configured for various turret modules containing turrets with different physical dimensions.
The press frame may incorporate the turret drive mechanisms that enable the drive shaft to be mounted above the turret. This frees up space in the module below the turret for incorporating vacuum, cleaning features, or used for other requirements, and reduces heat in the tableting zone generated by a turret motor typically mounted beneath the turret. Additionally, the module cost and weight are reduced by not having to incorporate the drive motor and assembly in the module.
Isolating and housing the control components in the frame avoids the requirement for calibration of pressure roll positions, load cells or strain gages, and turret speed when a module is detached or attached.
A precision pneumatic, hydraulic, magnetic, physical connection, or other method is incorporated to secure the turret module to the machine frame. Alignment and mounting are designed to ensure the module can be precisely detached and attached to the frame without impacting the machine performance.
The detachable turret module comprising a module base, turret housing, turret, cam body, cams, feeder, tablet discharge chute, hopper, and guard doors eliminates the requirement for an external cart and significantly reduces the changeover time. An operator simply disconnects the powder inlet connection, presses a detach module button in the tablet press HMI software, disconnects cable connector(s), if required, and uses an automated guided vehicle (AGV), or other appropriate material handling mechanism, to remove the module in a matter of minutes. The AGV may be integrated into the detachable turret module or may be removable. In accordance with the invention the AGV comprises a controllable lifting mechanism for raising and lowering the detachable module to selectively attach the detachable module to the machine frame.
The illustrated and described rotary press machine improves upon the prior art tablet presses by isolating the pressure roll assemblies in a separate and distinct machine frame from a detachable turret module comprising of a turret and the base on which it is supported to provide a faster changeover, increased configurability, offline setup, and a safer solution for the customer and eliminating the need to lift and remove a heavy turret unit and load it onto an ancillary cart. Sealing the module minimizes the operator's exposure to granulation dust particles and enables the module to be transferred to a cleaning room with less risk of cross contamination. Prior art presses incorporate mechanisms that attach to and drive the turret from beneath. Having a detachable module that incorporates the turret supporting base eliminates the requirement for an ancillary cart as well as the requirement to disconnect, move and/or remove press components and lift and load the compression unit and/or turret.
Referring initially to
In accordance with the invention, the machine frame 12 is designed to isolate the turret drive assembly and pressure roll assemblies, described below, in the machine frame 12 from the turret module 14 to provide a faster changeover, offline setup, increased configurability, and a safer solution for the customer. Having a detachable turret module 14 that incorporates the turret supporting base, described below, eliminates the requirement for an ancillary cart as well as the requirement to disconnect, move and/or remove press components and to lift and load the compression unit and/or turret.
The machine frame 12 comprises a press housing 16. The press housing 16 is generally parallelepiped in shape with a front inset portion 18 for receiving the detachable module 14. An upper end of the press housing 16 extends forwardly above the inset portion 18 and defines a drive housing 20 at the top of the press housing 16. A connection base 22 extends forwardly of the bottom of the press housing 16 and is aligned with the drive housing 20. A plurality of adjustable pads 24 are provided on an underside of the press housing 16 and connection base 22 for supporting and leveling the machine frame 12 on a ground surface.
The press housing 16 includes interior space for control components (not shown) and includes an operator control panel 26. Provision is also made for providing necessary electrical connections between control devices in the press housing 16. Referring also to
The press housing 16 houses two motorized pressure roll assemblies 36 and 38. Some designs may use a single pressure roll assembly. The first roller assembly 36 has an upper roller 40 and a lower roller 42. The second roller assembly 38 has an upper roller 44 and a lower roller 46. The rollers 40 and 42 are in a plane 120° to that of the rollers 44 and 46. The roller assemblies 36 and 38 are driven by linear drives, one of which is shown at 56, see
The drive housing 20 supports a turret drive torque motor 62 which drives a downwardly depending drive shaft 64. The motor 62 is also configured to raise and lower the drive shaft 64 using a piston 66 to engage a turret for rotation therewith.
Referring to
The turret module 14 comprises a module base 70 supporting a turret housing 72. A transparent outer wall 74 surrounds the front of the turret housing 72 to isolate the internal assemblies. The outer wall 74 may be of a clear polycarbonate material. The turret housing 72 has a top wall 76 supported on pillars 78 which are in turn supported on the module base 70. When the turret module 14 is secured to the machine frame 12, the turret module 14 is sealed by incorporating an upper enclosure via the outer wall 74. The back of the turret housing 72 is open to allow the pressure roll assemblies 36 and 38 to engage the upper and lower punches, as described below. The turret housing 72 may use conventional structure for sealing the turret housing 72 to the press housing 16.
In a rotary tablet press, a turret is rotatable about a vertical axis and carries a plurality of dies. Each die has associated top and bottom punches driven by top and bottom cams to compress the granulation into a tablet. An upper punch, a lower punch and a die are together referred to as a station. This is discussed below.
The turret housing 72 encloses a turret assembly 80. The turret assembly 80 is mounted to a support 81 which is in turn supported on the module base 70. The turret assembly 80 is rotatable relative to the support 81. The turret assembly 80 typically includes a die table and upper punch guide and lower punch guide assemblies. The turret module 14 houses the turret assembly 80 along with a cam body, cams, feeder, tablet discharge chute, and a hopper. As described below, the turret assembly 80 comprises chambers arranged circumferentially to hold upper punches, lower punches, and dies. As the turret assembly 80 rotates, punches follow a cam track and reciprocate into and out of dies that receive granulation as they are rotated under the feeder, as is conventional. A tablet is formed when the punches contact the pressure rolls 40, 42, 44 and 46 in
In accordance with the invention, the turret assembly 80 is driven by an inlet coupling 82 on the top wall 76 engageable by the drive shaft 64, see
Referring to
The support housing 88 has a bottom wall 102, see
With the module 14 positioned with the machine frame 12, as shown in
The AGV cart 94, shown in
The illustrated embodiment uses jackscrews 118 for raising and lowering the module base 70. Alternatively, the AGV cart could utilize a design that incorporates hydraulic lifting using a hydraulic pump, reservoir, valves, flow divider, and plural cylinders.
The machine control 150 is selectively connected via the connectors 28 and 106 to a turret control 156 in the turret module control housing 92. The turret control 156 controls operation of devices in the turret module 14 as necessary or desired. As the present invention is related particularly to features of securing the detachable module 14 to the machine frame 12, the details of the overall operation of the machine control 150 and the turret control 156 are not discussed herein.
In accordance with the invention, a manufacturer may have a plurality of different turret modules for use with a single machine frame 12. Each module can have a different turret assembly and appurtenances depending on the type of tablet to be produced. There will be at least four total configurations for this machine design utilizing a machine frame with compression and drive assemblies with a removable module including a turret, feeder, tablet discharge chute, hopper and cam assemblies. Each will offer different turret configurations. Also, different configurations of the machine frame 12 may be provided with different number and configuration of compression roller assemblies, as discussed below.
For example, the rotary tablet press in accordance with the invention may be configured to be Single Layer & Single Sided (one feeder, one product); Single Layer & Double Sided (two feeders, two products); Bilayer (two feeders, one product); and Trilayer (three feeders, one product). A single sided press has only one feeder, and it is designed to make a single layer tablet. It is designed with two equal size compression assemblies for pre-compression and main compression. A triple sided press has three feeders, and it is designed to make a triple layer containing three different granulations. It is designed with one large compression assembly for main compression.
As described in the illustrated embodiments, a rotary tablet press comprises a machine frame and detachable turret module. Granulation is fed into the module from a hopper and travels into the feeder chamber. The machine frame comprises motorized pressure roll assemblies and a turret drive assembly. The detachable turret module comprises a module base, turret base, turret, cam body, cams, feeder, tablet discharge chute, hopper, upper enclosure, and guard doors. The rotary turret comprises upper punches, dies, and lower punches. As the turret rotates, the dies move underneath the feeder chamber. The rotary feeder paddles move the granulation and assist with feeding powder to the dies. Punches travel along cam tracks as the turret rotates and compresses the powder into a tablet when the punches contact the pressure rolls. An ejection cam pushes the lower punch in the upward direction and a take-off bar mounted just above the die table directs the tablet into a discharge chute. The detachable module is sealed by incorporating an upper enclosure.
It will be appreciated by those skilled in the art that there are many possible modifications to be made to the specific forms of the features and components of the disclosed embodiments while keeping within the spirit of the concepts disclosed herein. Accordingly, no limitations to the specific forms of the embodiments disclosed herein should be read into the claims unless expressly recited in the claims. Although a few embodiments have been described in detail above, other modifications are possible. Other embodiments may be within the scope of the following claims.
The foregoing disclosure of specific embodiments is intended to be illustrative of the broad concepts comprehended by the invention.