This U.S. patent application claims priority under 35 U.S.C. §119 to: European Patent Application No. EP14198364.3, filed Dec. 16, 2014, and European Patent Application No. EP15197444.1 filed Dec. 2, 2015. The aforementioned applications are incorporated herein by reference in their entireties.
The invention relates to the field of charged particle accelerators, such as proton or carbon ion accelerators for example, and more particularly to a rotating energy degrader for attenuating the energy of a charged particle beam extracted from such a particle accelerator.
The invention also relates to a particle therapy system comprising a particle accelerator and a rotating energy degrader for attenuating the energy of a charged particle beam extracted from the particle accelerator.
Certain applications involving the use of beams of charged particles require the energy of these particles to be varied. This is for example the case in particle therapy applications, where the energy of the charged particles determines the depth of penetration of these particles into a body to be treated by such therapy. Fixed-energy particle accelerators, such as cyclotrons for instance, are not themselves adapted to vary the energy of the particle beam which they produce, and therefore require an additional device to vary this energy. Variable-energy particle accelerators, such as synchrotrons for instance, are themselves adapted to vary the energy of the particle beam which they produce, but it may nevertheless be desirable to further vary the energy after the particles have been extracted from a synchrotron.
Devices for varying the energy of a particle beam extracted from a particle accelerator are generally called energy degraders. An energy degrader comprises therefore one or more blocks of matter which are placed across the path of the particle beam after its extraction from the particle accelerator. According to a well-known principle, a charged particle passing through the thickness of such a block of matter undergoes a decrease in its energy by an amount which is, for particles of a given type, a function of the intrinsic characteristics of the material passed through and of said thickness.
Existing rotating energy degraders may include a single block of energy degrading material which has the shape of a plain helical staircase with discrete flat steps and which is placed across the path of the particle beam. The particle beam enters the degrader perpendicularly to a step of the staircase and exits the degrader at the opposite side, which attenuates the energy of the beam according to the thickness of the degrader at said step. After having rotated the staircase by a given angle around its axis, the particle beam will enter the degrader perpendicularly to another step and exit the degrader at the opposite side, which will attenuate the energy of the beam by a different amount according to the thickness of the degrader at said other step. The energy attenuation can thus varied by changing the angular position of the degrader with respect to the particle beam.
However, existing degraders must have a large diameter in order to have steps of sufficiently small height to obtain the resolution in energy variation which is required for particle therapy applications for example.
As a consequence, these degraders have a large moment of inertia, so that it is difficult to make them rotate quickly and/or with high accuracy with respect to the particle beam. Some recent applications require however to be able to change the energy of the particle beam very quickly, such as in a few tens of milliseconds for instance, and/or with high accuracy. This is for example the case with particle therapy systems, where a target, such as a tumour for example, is to be irradiated layer by layer with the particle beam, these layers being at different depths into the body of the patient. In such cases, it is desirable to be able to change the energy of the particle beam very quickly and/or very accurately when the system passes from the irradiation of one layer to the irradiation of another layer.
Another drawback of the large diameter of the known degraders is that they require large quantities of expensive energy degrading material, which make them quite costly. A further drawback of their large diameter is that they are cumbersome and occupy lots of space, especially footprint space.
Other existing degraders use a “comma”-shaped block of matter which is rotatably movable around an axis which is perpendicular to the “comma”. The beam crosses the comma in a direction which is perpendicular to the rotation axis and hence enters into the “comma” at an outer curved side of the “comma” and exits out of the “comma” at an inner curved side of the “comma”, or vice-versa. The energy attenuation is varied by changing the angular position of the “comma” with respect to the particle beam.
These energy degraders would also require a large diameter, particularly if they would be used for particle therapy applications, and therefore present similar drawbacks as the previously discussed, namely a high moment of inertia, high cost and high occupied volume.
It is an object of the invention to address the drawbacks of the known energy degraders. It is a particular object of the disclosure to provide an energy degrader which is adapted to vary the energy of a particle beam more quickly and/or with higher accuracy than the known degraders.
A typical beam energy at an input of an energy degrader according to the disclosure is in the MeV range, such as in the range of 150 MeV to 300 MeV for example, and a typical desired beam energy at an output of an energy degrader according to the disclosure is also in the MeV range, such as in the range of 50 MeV to 230 MeV for an upstream energy of 230 MeV for example.
According to the disclosure, there is provided an energy degrader for attenuating the energy of a charged particle beam extracted from a particle accelerator, said energy degrader comprising:
It is to be noted that a helical surface may have a close-up appearance of a helical staircase, for example in case an energy attenuation member is made with a 3D printer, but that it is still to be considered as a continuous helical surface in case a minimum run (tread depth) of its steps is smaller than a minimum average beam diameter at a level where the beam crosses the helical surface (for example a minimum run of its steps which is smaller than 8 mm in case of an average beam diameter ranging between 8 mm and 30 mm when crossing the helical surface).
As will also appear hereafter from the figures showing embodiments of the disclosure, the degrader is hence geometrically arranged so that the respective entry and exit faces of the energy attention members are disposed in the following (continuous or discontinuous) sequence with respect to the path of a charged particle beam crossing it:
By “discontinuous sequence”, it must be understood that additional attenuation material may be present in-between the beam exit and entry faces of respectively the first and second energy attenuation members, such as a flat material plate for example.
Thanks to the presence of the two energy attenuation members having their two facing and continuous helical surfaces with the same handedness, the diameter of the degrader can be made smaller than with known rotating degraders, yet providing for a good resolution in energy variation and for a limited statistical energy spread of the particles at the output of the degrader. With a smaller diameter, and hence a smaller moment of inertia, it will be possible to rotate the energy attenuation member(s) more quickly and therefore the energy of the particle beam can be varied more quickly. Such a degrader also requires less space.
Preferably, the beam entry face of the first energy attenuation member is perpendicular to the first axis and in the beam exit face of the second energy attenuation member is perpendicular to the second axis. This allows to limit even more the statistical energy spread of the particles at the output of the degrader.
Preferably, the drive assembly comprises a first motor for rotating the first energy attenuation member around the first axis and a second motor for rotating the second energy attenuation member around the second axis. Compared to a configuration wherein the first energy attenuation member would be fixed and the second energy attenuation member would be mobile in rotation, such a preferred configuration allows, for a given/desired energy attenuation, to position the first and second energy attenuation members independently from each other with respect to the particle beam, for example according to the characteristics of the beam optics at the beam entry and exit faces. It presents the further advantage to enable a faster and more accurate variation of the energy of the particle beam.
Preferably, the first and the second helical surfaces are cylindrical helical surfaces. More preferably, the first and the second helical surfaces have the same radius and the first axis is the same as the second axis. Even more preferably, the first and the second helical surfaces have the same pitch. Even more preferably, the first and second energy attenuation members are identical in shape and size. This allows easy and cheaper manufacturing of the degrader.
Alternatively, the radius of the first helical surface is smaller than the radius of the second helical surface, the pitch of the first helical surface is smaller than the pitch of the second helical surface, and the first axis is different from and parallel to the second axis. With such alternative, the first energy attenuation member will have an even smaller diameter and hence will be able to move even faster.
According to the disclosure, there is also provided a particle therapy system comprising a particle accelerator and an energy degrader according to the disclosure, said energy degrader being positioned and oriented with respect to a particle beam extracted from the particle accelerator, in such a way that the particle beam enters the energy degrader at the beam entry face of the first energy attenuation member and in such a way that said particle beam exits the energy degrader at the beam exit face of the second energy attenuation member. In case the beam entry face of the first energy attenuation member is perpendicular to the first axis and the beam exit face of the second energy attenuation member is perpendicular to the second axis, the energy degrader is preferably positioned and oriented with respect to a particle beam extracted from the particle accelerator, in such a way that the particle beam enters the energy degrader perpendicularly to the beam entry face of the first energy attenuation member.
Preferably, the particle accelerator is a fixed-energy accelerator, more preferably a cyclotron, even more preferably a synchrocyclotron.
These and further aspects of the disclosure will be explained in greater detail by way of example and with reference to the accompanying drawings in which:
a,
8
b,
8
c schematically show a front view of the energy degrader of
The drawings of the figures are neither drawn to scale nor proportioned. Generally, similar or identical components are denoted by the same reference numerals in the figures.
The energy degrader (1) comprises two disjoint energy attenuation members: a first energy attenuation member (10) and a second energy attenuation member (20).
The first energy attenuation member (10) presents a beam entry face (11) having the shape of an annulus (or a portion thereof), and it presents an opposed beam exit face (12) having the shape of a part of a first continuous helical surface having a first axis (A1).
The second energy attenuation member (20) presents a beam entry face (21) having the shape of part of a second continuous helical surface having a second axis (A2) which is parallel to or coincident with the first axis (A1), and it presents an opposed beam exit face (22) having the shape of an annulus or a portion thereof.
It is to be noted that a helical surface may have a close-up appearance of a helical staircase, for example in case an energy attenuation member is made with a 3D printer, but that it is still to be considered as a continuous helical surface in case a minimum run (tread depth) of its steps is smaller than a minimum average beam diameter at a level where the beam crosses the helical surface (for example a minimum run of its steps which is smaller than 8 mm in case of an average beam diameter ranging between 8 mm and 30 mm when crossing the helical surface).
As can be seen on
Preferably, the beam entry face (11) of the first energy attenuation member (10) is perpendicular to the first axis (A1) and the beam exit face (22) of the second energy attenuation member (20) is perpendicular to the second axis (A2). In such a preferred case, the beam entry face (11) of the first energy attenuation member (10) is of course parallel to the beam exit face (22) of the second energy attenuation member (20).
The energy degrader (1) further comprises a drive assembly which is operably connected to the first and the second energy attenuation members (10, 20). This drive assembly is configured for driving the first energy attenuation member (10) and/or the second energy attenuation member (20) into rotation around respectively the first axis (A1) and/or the second axis (A2), said first axis (A1) being parallel to or coincident with said second axis (A2).
The drive assembly may for example comprise a single motor as well as an optional transmission linking said single motor to the first energy attenuation member (10) so as to rotate the first energy attenuation member (10) around the first axis (A1), the second energy attenuation member (20) being fixed (not rotating).
Alternatively, the drive assembly may for example comprise a single motor as well as a transmission linking said single motor to respectively the first and the second energy attenuation members so as to rotate respectively the first and the second energy attenuation members, preferably in opposite directions (i.e. when the first energy attenuation member (10) is driven to rotate clockwise, the second energy attenuation member (20) will be driven to rotate anticlockwise and vice-versa).
Preferably, and as shown on
On
Preferably, the first and the second helical surfaces are cylindrical helical surfaces, as can be seen from on the example of
In order to have the same slope on both helical surfaces, the pitch of the first helical surface is preferably smaller than the pitch of the second helical surface.
The rotor of the first motor (M1) comprises a mechanical coupling (40) to the said shaft (30) for driving the shaft (30) into rotation while allowing an axial translation movement of the shaft (30). In this example, said mechanical coupling (40) comprises a “U”-shaped part having two flat inner portions (40a, 40b) slidingly engaging with respectively two flat external faces (30a, 30b) of a distal portion of the shaft (30).
The rotor of the first motor (M1), the threaded hole, the first helical surface of the first energy attenuation member (10) and the said shaft (30) are all coaxial in this example and have as axis the first axis (A1).
The pitch and the handedness of the threaded portion (31) of the shaft (30) (and hence also of the threaded hole of the guiding piece (35)) are the same as respectively the pitch and the handedness of the first helical surface.
It will therefore be understood that the drive assembly is adapted to move the first energy attenuation member (10) according to a helical movement around the first axis (A1), as shown by a helical double arrow on
In this example, the rotor of the first motor (M1) is directly connected to the mechanical coupling (40). Preferably, the rotor of the first motor (M1) is connected to the mechanical coupling (40) via a speed reducer—such as a speed reduction gearbox for example—in order to increase the accuracy of the movement.
The second energy attenuation member (20) is preferably connected in the same way to the second motor (M2) (not shown on
Preferably, the first and second helical surfaces each make a turn of less than 360°, more preferably less than 270°, even more preferably less than or equal to 180° around their respective axis.
a,
8
b,
8
c schematically show a front view of the energy degrader (1) of
Preferably, the first energy attenuation member (10) and/or the second energy attenuation member (20) are made of beryllium or carbon graphite. More preferably, the first energy attenuation member (10) is made of the same material as the second energy attenuation member (20).
As schematically shown on
The energy degrader (1) is positioned and oriented with respect to a particle beam (2) extracted from the particle accelerator (100), in such a way that the particle beam (2) enters the energy degrader (1) at the beam entry face (11) of the first energy attenuation member (10) and in such a way that said particle beam (2) exits the energy degrader (1) at the beam exit face (22) of the second energy attenuation member (20). Preferably, the beam entry face (11) of the first energy attenuation member (10) is parallel to beam exit face (22) of the second energy attenuation member (20) and it is perpendicular to the first axis (A1), the latter being parallel to or coincident with the second axis (A2). In this case, the energy degrader (1) is preferably positioned and oriented with respect to the particle beam (2), in such a way that the particle beam enters the energy degrader (1) perpendicularly to the beam entry face (11) of the first energy attenuation member (10), as shown on
For the sake of clarity,
Preferably, the particle accelerator (100) is a fixed-energy accelerator, preferably a cyclotron, more preferably a synchrocyclotron.
Preferably, the particle accelerator (100) is configured for delivering at its output (110) a particle beam (2) whose maximal energy is comprised between 1 MeV and 500 MeV, preferably between 100 MeV and 300 MeV, more preferably between 200 MeV and 250 MeV.
In such a case, a typical desired beam energy at an output (22) of an energy degrader (1) according to the disclosure is also in the MeV range, such as in the range of 50 MeV to 230 MeV for an upstream energy of 230 MeV for example. With these energies, one preferably has that:
Disclosed embodiments may also be described as follows: an energy degrader (1) for attenuating the energy of a charged particle beam (2), comprising a first energy attenuation member (10) presenting a annular beam entry face and a helical beam exit face, a second energy attenuation member (20) presenting a helical beam entry face and an annular beam exit face, the first and second helical surfaces facing each other, and a drive assembly configured for rotating the first and the second energy attenuation members around respectively a first axis (A1) and a second axis (A2) which are parallel to each other.
The present disclosure has been described in terms of specific embodiments, which are illustrative of the embodiments and not to be construed as limiting. More generally, it will be appreciated by persons skilled in the art that the disclosed embodiments are not limited by what has been particularly shown and/or described hereinabove.
Reference numerals in the claims do not limit their protective scope.
Use of the verbs “to comprise”, “to include”, “to be composed of”, or any other variant, as well as their respective conjugations, does not exclude the presence of elements other than those stated.
Use of the article “a”, “an” or “the” preceding an element does not exclude the presence of a plurality of such elements.
Number | Date | Country | Kind |
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14198364.3 | Dec 2014 | EP | regional |
15197444.1 | Dec 2015 | EP | regional |