The present invention concerns a rotor of the type intended to be driven in rotation about a central axis of rotation and wherein a number n of seats for receiving a product to be centrifuged are provided, the seats being arranged eccentrically relative to the axis of rotation.
The invention applies, for example, to the centrifuging of biological products.
For the centrifuging of such products, rotors of frustoconical shape are generally used in which the seats have been provided in the form of recesses. These seats are elongate in shape and, for each rotor, are regularly distributed about its axis of rotation. The seats are intended to receive, for example, tubes containing the products to be centrifuged and closed by means of stoppers.
A centrifuge using such a rotor generally comprises a trough, equipped with cooling means and in which the rotor is mounted on a rotational drive head.
In ultra-centrifuges, that is to say, centrifuges driving the rotors at speeds of the order of 20,000 r.p.m., the occurrence of excessive noise nuisance such as whistling has been observed.
It is an aim of the invention to solve this problem by limiting the excessive noise nuisance caused by the driving in rotation of rotors of the aforesaid type.
To this end, the subject of the invention is a rotor of the aforesaid type, wherein the geometric image of at least a first seat, through a geometric rotation about the axis of rotation in a first direction of rotation and an angle of 360°/n, is different from a second seat which directly follows the first seat in the first direction of rotation.
According to particular embodiments, the rotor may comprise one or more of the following characteristics, taken singly or in all the combinations technically possible:
A further subject of the invention is a centrifuge comprising a trough, a rotor intended to be disposed in the trough, and means for driving the rotor in rotation, characterised in that the rotor is a rotor as defined above.
The invention will be more clearly understood on reading the following description, provided solely by way of example and with reference to the appended drawings, in which:
In a conventional manner, the trough 2 comprises a movable access door 6 and means for cooling its internal atmosphere, which cooling means are not shown in the drawings.
The rotor 3 is a rotor of generally frustoconical shape with a central axis A. It is equipped with a removable closure lid 7. The lid 7 has not been shown in
The rotor 3 is for example made from metal and four seats, arranged eccentrically relative to the axis A, are provided therein, that is to say, a first pair of seats 81 and 82 and a second pair of seats 101 and 102. It will be noted that the seats 101 and 102 are not shown in
The seats 81 and 82 of the first pair are symmetrical to each other relative to the axis A. The seats 101 and 102 of the second pair are symmetrical to each other relative to the axis A.
The seats 81, 82, 101 and 102 are of an analogous shape, elongate in a respective longitudinal direction D.
As can be seen in
The seats 81, 82, 101, and 102 open into the upper surface 12 of the rotor to make it possible, when the lid 7 is withdrawn, to introduce into the seats recipients containing the product(s) to be centrifuged, for example tubes closed by means of stoppers.
In
As can be seen in
If such distribution were regular, the rotor 3 would be invariant through a geometric rotation of axis A and angle equal to 90° (π/2 rad). Thus, the geometric image I (double-dash/dotted line) of the seat 81 through such a rotation in a first direction S1 would coincide with the seat 101, which seat directly follows the seat 81 in that direction S1.
In the rotor of
In other words, the seat 101 is the image, through a geometric rotation of axis A and angle α, of the image I.
Thus, the longitudinal directions D of the seats 101 and of the image I form, in a view from above, an angle α centred on the axis A and negative when considering the direction S1.
The angle α is, for example, 4° and may more generally be between 2° and 10°.
It will be noted that in
Similarly, the seat 102 is offset angularly, in a view from above, from the image, not shown, of the seat 82 through the aforesaid rotation.
Thus, the seats 81, 82, 101 and 102 are invariant through a geometric rotation of axis A and angle equal to 180° (π rad) but not through a rotation of axis A and angle equal to 90° (π rad) as in the state of the art.
It was found, when driving the rotor 3 in rotation at relatively high speeds, typically above 10,000 r.p.m., that the excessive noise nuisances such as whistling are severely reduced, or even eliminated.
It is considered at present that the reason for this reduction or elimination of excessive noise nuisance may be as follows. When the rotor 3 is driven in rotation, the areas Z (
Moreover, the imbalances caused by the irregularity of arrangement of the seats are relatively small and acceptable owing to the fact that α is relatively small.
According to a variant of the embodiment of
More generally, other arrangements of the seats 81, 82, 101 and 102 may be envisaged.
Thus, in the embodiment of
The distance d is for example 2 mm and may more generally be between 1 and 5 mm.
It will be noted that in
Since this distance is relatively short, the difference between the centrifuging forces to which the products received in the seats 81, 82, 101 and 102 will be subjected will remain sufficiently small and acceptable for the homogeneity of the centrifuging treatment. Similarly, the imbalances caused by the irregularity of arrangement remain acceptable.
According to a variant not shown, the seat 101, in a view from above, may be offset laterally from the image I of the seat 81 in the direction S1.
More generally, the seat 101, in a view from above, may be the issue of a geometric translation of the image I, the direction of this translation being not necessarily orthogonal to the direction D of the image I.
Still more generally, the seat 101 may be deduced from the image I of the seat 81 through a geometric transformation in a radial plane containing the axis of rotation A and the longitudinal direction D of the image I.
Thus,
It will be noted that the angle β may be positive or negative. The angle β has for example a value of 4° and may more generally be between 2° and 10°.
It will be noted that in
It will also be noted that the angle β or the distance δ are small enough on the one hand for the homogeneity of the centrifuging treatment undergone by products received in the seats 81, 82, 101 and 102 to be satisfactory and on the other hand for the imbalances to be reduced.
More generally, the above principles may be applied to rotors comprising any number of seats.
They may also be combined with one another for the same seat.
Thus,
More precisely, the rotation is a rotation of axis A and angle α.
The translation is a translation in the plane of
The combination of a rotation and a translation within the geometric transformation allows the seat 101 to remain close enough to the image I to limit the differences between the centrifuging force undergone by a product contained in the seat 101 and the centrifuging force of a product received in the seat 81.
Thus, the homogeneity of the centrifuging treatment undergone by products received in the seats 81, 82, 101 and 102 is increased. Moreover, this combination makes it possible to reduce the imbalances and also the difference in appearance between a rotor incorporating the principles of the invention and a conventional rotor.
Similarly,
More precisely, the rotation is a rotation of non-zero angle β and the translation is a translation by a non-zero distance δ in a direction orthogonal to the axis of rotation A.
Here again, the combination of a translation and a rotation makes it possible to increase the homogeneity of the centrifuging treatment undergone by products received in the seats 81, 82, 101 and 102, to limit the imbalances and to reduce the aesthetic problems.
More generally, the geometric transformation between the image I and the seat 101 may comprise a translation and/or a rotation in a plane orthogonal to the axis of rotation A, and a translation and/or a rotation in a radial plane containing the axis A.
Generally, also, the translations and rotations described previously may be applied, for example each separately to a respective pair of seats when the number of seats is even and strictly greater than 4.
Preferably, the seats are symmetrical in pairs relative to the axis A. Thus, when the rotor 3 is equipped with an even number n of seats, the rotor 3 will be invariant through a geometric rotation of axis A and angle 180°, thereby making it possible to limit the imbalances. More generally, an invariance through a geometric rotation of axis A and angle strictly greater than 360°/n will make it possible to limit the imbalances.
In order to avoid the occurrence of excessive noise nuisance, there will still be at least a first seat, the geometric image of which, through a geometric rotation about the axis of rotation A and an angle 360°/n in one direction of rotation, is different from a second seat of the rotor, the second seat directly following the first seat in the selected direction of rotation.
Number | Date | Country | Kind |
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02 00219 | Jan 2002 | FR | national |
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Number | Date | Country | |
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20030158026 A1 | Aug 2003 | US |