Claims
- 1. A ruminal drug delivery device and insert combination, the combination comprising a ruminal drug delivery device having a semipermeable cup defining a compartment, an osmotic expandable driving member, a drug formulation containing a drug to be dispensed, a density element, and exit means for fluidly connecting the drug formulation with the environment of use, and an insert, the insert being essentially gas-impermeable and being sized and shaped to be placed between a density element and the drug formulation.
- 2. A combination as set forth in claim 1, wherein the insert is retained within the compartment and the density element retained within the insert.
- 3. A combination according to claim 1, wherein the insert comprises a material selected from the group consisting of polyvinyl alcohol, polypropylene, cellulose, cellulose esters, acetyl resins, fluorocarbon polymers, polyamides, polyesters, polyolefins, nylon, and noncorrosive metals.
- 4. A combination according to claim 1, wherein the insert further comprises venting means.
- 5. A combination according to claim 4 wherein the venting means is selected from the group consisting of one or more protrusions, one or more grooves, one or more bores, and combinations thereof.
- 6. A combination according to claim 1, wherein the insert further comprises an exit port screen.
- 7. A combination according to claim 1, wherein the insert further comprises a loading dose chamber and a loading dose.
CROSS-REFERENCE TO COPENDING APPLICATIONS
This application is a continuation of the parent application, application Ser. No. 08/743,807, filed Nov. 5, 1996, now U.S. Pat. No. 5,824,340, which is a divisional of application Ser. No. 08/475,916, filed Jun. 7, 1995, now U.S. Pat. No. 5,639,477, which is a continuation-in-part of U.S. patent application Ser. No. 08/081,743, filed Jun. 23, 1993, now U.S. Pat. No. 5,431,919.
US Referenced Citations (10)
Foreign Referenced Citations (1)
Number |
Date |
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9011856 |
Oct 1990 |
WOX |
Divisions (1)
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Number |
Date |
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Parent |
475916 |
Jun 1995 |
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Continuations (1)
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Number |
Date |
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Parent |
743807 |
Nov 1996 |
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Continuation in Parts (1)
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Number |
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081743 |
Jun 1993 |
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