Claims
- 1. A compound having the formula: ##STR9## wherein R".sub.1 and R".sub.2 are independently lower alkyl, or a pharmaceutically acceptable salt, ester or amide thereof.
- 2. A compound having the formula: ##STR10## wherein R".sub.1 and R".sub.2 taken together are C.sub.3-13 -alkylene in which one carbon atom may be substituted by a heteroatom selected from the group consisting of sulfur, oxygen and nitrogen, or a pharmaceutically acceptable salt, ester or amide thereof.
- 3. A compound having the formula: ##STR11## wherein R".sub.1 and R".sub.2 taken together with the carbon atoms to which they are attached are an aromatic ring having from 5-6 carbon atoms or a heteroaromatic ring having from 5-6 atoms in which one atom of R".sub.1 or R".sub.2 is a heteroatom selected from the group consisting of oxygen, nitrogen and sulfur and the remaining atoms of R".sub.1 and R".sub.2 are carbon, or a pharmaceutically acceptable salt, ester or amide thereof.
- 4. (2E,4E)-3-methyl-5-(2-((E)-2(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl)-1-cyclohepten-1-yl)-2,4-pentadienoic acid.
- 5. (2E,4E)-3-Methyl-5-(2-((E)-2(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl)-1-cycloocten-1-yl)-2,4-pentadienoic acid.
- 6. The compound of claim 2 wherein R".sub.1 and R".sub.2 taken together are C.sub.3-13 -alkylene.
- 7. The compound of claim 6 wherein R".sub.1 and R".sub.2 taken together are C.sub.3-6 -alkylene.
- 8. The compound of claim 7 wherein said compound is (2E,4E)-3-Methyl-5-[2-(2,6,6-trimethyl-cyclohex-1-enylethynyl)-cyclopent-1-enyl]-penta-2,4-dienoic acid.
- 9. The compound of claim 7 wherein said compound is (2E,4E)-3-Methyl-5-[2-(2,6,6-trimethyl-cyclohex-1-enylethynyl)-cyclohept-1-enyl]-penta-2,4-dienoic acid.
- 10. The compound of claim 3 wherein said ring is selected from the group consisting of thiophene, benzene and pyridine.
- 11. The compound of claim 10 wherein said compound is (2E,4E)-3-Methyl-5-[2-(2,6,6-trimethyl-cyclohex-1-enylethynyl)-phenyl]-penta-2,4-dienoic acid.
Parent Case Info
This is a division of application Ser. No. 08/732,630, filed Oct. 16, 1996, abandoned, which is a divisional of Ser. No. 08/468,289, filed Jun. 6, 1995, now abandoned, which is a continuation-in-part of application Ser. No. 08/393,980, filed Feb. 24, 1995 (now abandoned).
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5514672 |
Bazzano |
May 1996 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
718 285 A2 |
Jun 1996 |
EPX |
Non-Patent Literature Citations (1)
Entry |
Paust et al, "Agent containing an all-E- or 13-Z-7,8-dehydroretinoic acid", Chem. Abs.No.93:155854, 1980. |
Divisions (2)
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Number |
Date |
Country |
Parent |
732630 |
Oct 1996 |
|
Parent |
468289 |
Jun 1995 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
393980 |
Feb 1995 |
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