This Small Business Innovation Research (SBIR) Phase I project proposes to develop an automated method for fabricating and analyzing microarrays without the use of a robotic spotter. The method involves the use of a PDMS (poly- dimethylsiloxane) microfluidic tool for depositing and interrogating linear protein arrays with an interface to 96 well plates. <br/><br/>The commercial application of this project will be in the area of protein microarrays for use in biological and pharmaceutical research.