SBIR Phase I: Biocompatible Magnetic Drug Delivery Systems that Allow for Greatly Diminished Doses

Information

• NSF Award
• 0319444

Owner

• Nanosonics Limited

• Award Id

  0319444

• Award Effective Date

  7/1/2003 - 21 years ago

• Award Expiration Date

  12/31/2003 - 20 years ago

• Award Amount

  $ 99,999.00

• Award Instrument

  Standard Grant

This Small Business Innovation Research (SBIR) Phase I project is to develop noble metal and polymer stabilized magnetic nanoparticles and biodegradable microspheres as nanovehicles for use in magnetically guided drug delivery. Site-specific release of therapeutic agents results in greatly reduced whole body dosages to minimize toxicity. Controlled, ultra thin coatings for magnetic nanoparticles would yield biocompatible systems with significantly improved magnetic susceptibility required for effective magnetic guidance through the arterial system. Analgesics and stable magnetic nanoparticles would be contained in and subsequently released from biodegradable polymeric microspheres.<br/><br/>The commercial applications of these highly magnetic nano-vehicles would be as Nuclear Magnetic Resonance (NMR) imaging contrast agents, magnetically guided drug delivery systems, and for cell separation techniques.

• Program Officer

  Om P. Sahai

• Min Amd Letter Date

  6/3/2003 - 21 years ago

• Max Amd Letter Date

  6/3/2003 - 21 years ago

• ARRA Amount

• Name

  Nanosonic Inc.

• City

  Pembroke

• State

  VA

• Country

  United States

• Address

  158 Wheatland Drive

• Postal Code

  241363645

• Phone Number

  5406266266

• First Name

  Dr. Jennifer

• Last Name

  Lalli

• Email Address

  jlalli@nanosonic.com

• Start Date

  6/3/2003 12:00:00 AM

• Name

  Health

• Code

  203000

• Text

  SMALL BUSINESS PHASE I

• Code

  5371

• Text

  BIOPROCESSING/BIOMOLECULAR MATERIALS

• Code

  9181

• Text

  BIOTECHNOLOGY