SBIR Phase I: Genomic Mapping of DNA by Means of Gene Engine\(TM\) Technology

Information

• NSF Award
• 0213876

Owner

• US Genomics, Inc.

• Award Id

  0213876

• Award Effective Date

  7/1/2002 - 22 years ago

• Award Expiration Date

  12/31/2002 - 22 years ago

• Award Amount

  $ 99,873.00

• Award Instrument

  Standard Grant

This Small Business Innovation Research (SBIR) Phase I Project proposes to refine the novel Gene Engine Technology foruse in effective and inexpensive genomic analysis. The specific objectives of this project are to experimentally determine the actual limits of applicability of the Gene Engine TM technology and to develop all components needed for its use in high-resolution genomic mapping. To accomplish this, fluorescent sequence-specific tags will be designed and methodsdeveloped for their attachment to DNA targets. Microfluidic system will be improved to reliably stretch long DNA fragments. Algorithms needed for data processing and DNA map building will be developed. During the Phase I study, mixture of DNA fragments up to 200 kilobases long will be analyzed. Further development will lead to design and commercialization of an instrument capable of analyzing genomes up to 10 megabases in length.<br/><br/>The commercial applications of this project will be for rapid screening of populations as well as for personalized genetic analysis in clinical settings in the form of routine laboratory tests.

• Program Officer

  Om P. Sahai

• Min Amd Letter Date

  6/11/2002 - 22 years ago

• Max Amd Letter Date

  6/11/2002 - 22 years ago

• ARRA Amount

• Name

  U.S. GENOMICS INC

• City

  WOBURN

• State

  MA

• Country

  United States

• Address

  12 GILL ST

• Postal Code

  018011743

• Phone Number

  7819375550

• First Name

  Rudolf

• Last Name

  Gilmanshin

• Email Address

  r.gilmanshin@fdsonics.com

• Start Date

  6/11/2002 12:00:00 AM

• Name

  Health

• Code

  203000

• Name

  Biomaterials-Short & Long Terms

• Code

  510402