Science and Ethics of Genome Engineering

Information

  • Research Project
  • 9998985
  • ApplicationId
    9998985
  • Core Project Number
    R25GM129218
  • Full Project Number
    5R25GM129218-04
  • Serial Number
    129218
  • FOA Number
    PAR-14-228
  • Sub Project Id
  • Project Start Date
    8/4/2017 - 7 years ago
  • Project End Date
    7/31/2022 - 2 years ago
  • Program Officer Name
    BECK, LAWRENCE A
  • Budget Start Date
    8/1/2020 - 4 years ago
  • Budget End Date
    7/31/2021 - 3 years ago
  • Fiscal Year
    2020
  • Support Year
    04
  • Suffix
  • Award Notice Date
    7/31/2020 - 4 years ago

Science and Ethics of Genome Engineering

Abstract  Research has shown that teacher effectiveness is closely correlated with improved student performance  in the classroom.  This project describes a professional development experience designed to increase  both the content knowledge of teachers and to sharpen their pedagogical skills.  The content focus of  the project will address the integration of basic concepts of genetics with the molecular genetics of  today, and the new science of genome engineering that will shape tomorrow. The project will also train  teachers in a pedagogy that values questions over answers and encourages students to develop their  critical thinking skills.    The professional development experience is designed around two one?week long workshops, held in  successive summers.  Teachers will be introduced to a collection of innovative tactile teaching tools  designed to function as thinking tools in the hands of students.  In addition, teachers will be introduced  to a series of molecular stories of current research and shown how foundational concepts of biology can  be taught within the context of these stories.  A unique feature of this project will occur during the  second summer workshop ? hosted by the science outreach groups at the Broad Institute at MIT and  Harvard or the Innovative Genomics Initiative (IGI) at UC Berkeley ? where teachers will experience  science as a process of discovery as they interact with researchers who are actively involved in the  development of genome editing technology.  This project is well aligned with the CoSTEM Strategic Plan and the SEPA program's goal of training a  more diverse biomedical workforce.  Three cohorts of twenty?four high school science teachers each will  be directly impacted by this project.  These teachers will be recruited from our local, urban Milwaukee  Public School system and from a national pool of teachers. During teacher recruitment, preference will  be given to those who teach in schools with a predominantly URM student population ? such that a  minimum of 50% of the teachers enrolled in each cohort will serve predominantly students who are  currently under?represented in science careers.  This project represents a partnership between the MSOE Center for BioMolecular Modeling and (i) the  science outreach groups at The Broad Institute and the IGI, (ii) the Protein DataBank, (iii) Milwaukee  Public Schools, (iv) the CTSI of Southeastern Wisconsin, and (v) R. Alta Charo, a noted bioethicist with  expertise in genome editing.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R25
  • Administering IC
    GM
  • Application Type
    5
  • Direct Cost Amount
    243762
  • Indirect Cost Amount
    19501
  • Total Cost
    263263
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    859
  • Ed Inst. Type
    BIOMED ENGR/COL ENGR/ENGR STA
  • Funding ICs
    NIGMS:263263\
  • Funding Mechanism
    OTHER RESEARCH-RELATED
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    MILWAUKEE SCHOOL OF ENGINEERING
  • Organization Department
    BIOCHEMISTRY
  • Organization DUNS
    006433452
  • Organization City
    MILWAUKEE
  • Organization State
    WI
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    532023109
  • Organization District
    UNITED STATES