Claims
- 1.-38. (Cancelled).
- 39. An isolated polynucleotide comprising a coding sequence consisting of the nucleotide sequence of SEQ ID NO: 75.
- 40. The polynucleotide of claim 39, wherein said polynucleotide is operably linked to at least one expression control sequence.
- 41. A host cell transformed with the polynucleotide of claim 40.
- 42. The host cell of claim 41, wherein said cell is a mammalian cell.
- 43. An isolated polynucleotide comprising a coding sequence consisting of the cDNA insert of clone dw665—4 deposited under accession number ATCC 98818.
- 44. An isolated polynucleotide comprising a coding sequence consisting of the nucleotide sequence of SEQ ID NO:75 from nucleotide 71 to nucleotide 1441.
- 45. An isolated polynucleotide coding sequence that encodes a protein consisting of the amino acid sequence of SEQ ID NO:76.
- 46. An isolated polynucleotide that hybridizes under conditions at least as stringent as 1×SSC at 65 degrees C., or 1×SSC at 42 degrees C. with 50% formamide, followed by washing in 0.3×SSC at 65 degrees C., to a complement of the polynucleotide of claim 39.
- 47. An isolated polynucleotide that hybridizes under conditions at least as stringent as 1×SSC at 67 degrees C., or 1×SSC at 45 degrees C. with 50% formamide, followed by washing in 0.3×SSC at 67 degrees C., to a complement of the polynucleotide of claim 39.
- 48. An isolated polynucleotide having at least 90% sequence identity to the polynucleotide of claim 39.
- 49. An isolated polynucleotide having at least 95% sequence identity to the polynucleotide of claim 39.
- 50. A process for producing a protein encoded by the polynucleotide of any one of claims 39 and 43 to 49, which process comprises:
(a) growing a culture of a host cell transformed with said polynucleotide in a suitable culture medium; and (b) purifying said protein from the culture.
- 51. An isolated polynucleotide comprising a coding sequence consisting of the nucleotide sequence of SEQ ID NO:85.
- 52. The polynucleotide of claim 51, wherein said polynucleotide is operably linked to at least one expression control sequence.
- 53. A host cell transformed with the polynucleotide of claim 52.
- 54. The host cell of claim 53, wherein said cell is a mammalian cell.
- 55. An isolated polynucleotide comprising a coding sequence consisting of the cDNA insert of clone kj320—1 deposited under accession number ATCC 98818.
- 56. An isolated polynucleotide comprising a coding sequence consisting of the nucleotide sequence of SEQ ID NO:85 from nucleotide 391 to nucleotide 3210.
- 57. An isolated polynucleotide coding sequence that encodes a protein consisting of the amino acid sequence of SEQ ID NO:86.
- 58. An isolated polynucleotide that hybridizes under conditions at least as stringent as 1×SSC at 65 degrees C., or 1×SSC at 42 degrees C. with 50% formamide, followed by washing in 0.3×SSC at 65 degrees C., to a complement of the polynucleotide of claim 51.
- 59. An isolated polynucleotide that hybridizes under conditions at least as stringent as 1×SSC at 67 degrees C., or 1×SSC at 45 degrees C. with 50% formamide, followed by washing in 0.3×SSC at 67 degrees C., to a complement of the polynucleotide of claim 51.
- 60. An isolated polynucleotide having at least 90% sequence identity to the polynucleotide of claim 51.
- 61. An isolated polynucleotide having at least 95% sequence identity to the polynucleotide of claim 51.
- 62. A process for producing a protein encoded by the polynucleotide of any one of claims 51 and 55 to 61, which process comprises:
(a) growing a culture of a host cell transformed with said polynucleotide in a suitable culture medium; and (b) purifying said protein from the culture.
Parent Case Info
[0001] This application is a continuation-in-part of the following applications:
[0002] (1) provisional application Ser. No. 60/084,564, filed May 7, 1998;
[0003] (2) provisional application Ser. No. 60/087,645, filed Jun. 2, 1998;
[0004] (3) provisional application Ser. No. 60/093,712, filed Jul. 22, 1998;
[0005] (4) provisional application Ser. No. 60/094,935, filed Jul. 31, 1998;
[0006] (5) provisional application Ser. No. 60/095,880, filed Aug. 10, 1998;
[0007] (6) provisional application Ser. No. 60/096,068, filed Aug. 11, 1998;
[0008] all of which are incorporated by reference herein.
Provisional Applications (6)
|
Number |
Date |
Country |
|
60084564 |
May 1998 |
US |
|
60087645 |
Jun 1998 |
US |
|
60093712 |
Jul 1998 |
US |
|
60094935 |
Jul 1998 |
US |
|
60095880 |
Aug 1998 |
US |
|
60096068 |
Aug 1998 |
US |
Continuations (1)
|
Number |
Date |
Country |
Parent |
09306111 |
May 1999 |
US |
Child |
10821273 |
Apr 2004 |
US |