Claims
- 1. A dispensing and applicator system for applying a plurality of dermatological agents, comprising:
- (a) a flexible, moisture impermeable support sheet having a first side and a second side;
- (b) a first applicator pad affixed to the first side of said support sheet, and a second applicator pad attached to the second side of said support sheet; said first pad being impregnated with a first composition comprising a first dermatological agent and said second pad being impregnated with a second composition comprising a second dermatological agent; and
- (c) a first flexible, moisture impermeable cover sheet having a first peripheral surface of a first side releasably sealed by a continuous seal line to the peripheral surface of the first side of said support sheet; and a second flexible moisture impermeable cover sheet, having a first peripheral surface of a first side releasably sealed by a continuous seal line to the peripheral surface of the second side of said support sheet; so as to form two compartments each containing one of said pads, each compartment being defined by a continuous seal line, which seal lines are positioned inwardly from the edges of the sheets over a portion of the opposed peripheral surfaces, so as to form two pairs of opposed flanges; each pair of the flanges being separable to release each cover sheet from the support sheet, so that said pads are exposed.
- 2. The dispensing and applicator system according to claim 1, wherein the cover sheet and the support sheet are made of a deformable plastic coated foil.
- 3. The dispensing and applicator system according to claim 1, wherein the cover sheet and the support sheet are sealed together by heat sealing or by an adhesive.
- 4. The dispensing and applicator system according to claim 1, wherein the applicator pads are made of natural fiber, synthetic fiber or foam.
- 5. The dispensing and applicator system according to claim 1, wherein the first dermatological agent is an effective anti-acne amount of a peroxide.
- 6. The dispensing and applicator system according to claim 5, wherein the first dermatological agent comprises benzoyl peroxide.
- 7. The dispensing and applicator system according to claim 5, wherein the first applicator pad is impregnated with a first composition comprising an effective anti-acne amount of an organic peroxide in combination with an aqueous gel comprising about 40-75% water, about 0.25-5% of an inorganic gelling agent, and about 2.5-10% of a mixture of an inorganic emollient oil and an emollient organic ester.
- 8. The dispensing and applicator system according to claim 7, wherein the first composition further comprises about 0.025-0.25% of an amphoteric surfactant.
- 9. The dispensing and applicator system according to claim 8, wherein the first composition further comprises about 10-20% of a (C.sub.2 -C.sub.4)alkanol.
- 10. The dispensing and applicator system according to claim 5, wherein the first applicator pad is impregnated with a first gelled composition comprising an effective anti-acne amount of an organic peroxide dispersed in about 50-80% water in combination with an effective amount of an inorganic gelling agent.
- 11. The dispensing and applicator system according to claim 5, wherein the first applicator pad is impregnated with a first gelled anhydrous composition comprising an effective anti-acne amount of an organic peroxide, about 75-90% of a mixture of inorganic and organic emollient oils, and about 1-10% of an inorganic gelling agent.
- 12. The dispensing and applicator system according to claim 11, wherein the composition further comprises about 0.1-1% of an amphoteric surfactant.
- 13. The dispensing and applicator system according to claim 5, wherein the second dermatological agent is an effective anti-acne amount of an antibiotic selected from the group consisting of erythromycin, tetracycline, clindamycin and the pharmaceutically acceptable salts thereof.
- 14. The dispensing and applicator system according to claim 13, wherein the antibiotic is clindamycin or a pharmaceutically acceptable salt thereof.
- 15. The dispensing and applicator system according to claim 13, wherein the second composition comprises about 0.1-5% of the antibiotic dissolved or dispersed in mixture of water and a water-miscible organic solvent.
- 16. The dispensing and applicator system according to claim 15, wherein the second composition comprises an emulsion of about 0.1-5% clindamycin, erythromycin or a pharmaceutically acceptable salt thereof, about 80-95% aqueous alcohol and about 5-15% emollient organic esters.
- 17. The dispensing and applicator system according to claim 1, wherein the first dermatological agent is an effective keratolytic amount of salicylic acid.
- 18. The dispensing and applicator system according to claim 17, wherein the first composition comprises an aqueous-alcohol gel comprising about 0.5-10% salicylic acid.
- 19. The dispensing and applicator system according to claim 18, wherein the gel comprises about 0.5-5% of an organic gelling agent.
- 20. The dispensing and applicator system according to claim 1, wherein the first dermatological agent is an effective anti-acne amount of retinoic acid.
- 21. The dispensing and applicator system according to claim 20, wherein the first dermatological composition comprises about 0.01-0.25% retinoic acid.
- 22. The dispensing and applicator system according to claim 21, wherein the first dermatological composition further comprises a gelled mixture of water with a water-miscible organic solvent.
- 23. The dispensing and applicator system according to claim 20, wherein the first dermatological composition comprises about 0.01-25% retinoic acid, about 50-85% water, about 4-12% emollient oil, about 3-10% emollient wax stabilizer, about 5-20% polyhydric alcohol emollient and about 0.5-10% organic, water-soluble surfactant.
- 24. The dispensing and applicator system according to claim 20, wherein the second dermatological composition comprises an effective amount of one or more sunscreen compounds.
- 25. The dispensing and applicator system according to claim 20, wherein the second dermatological composition comprises about 50-85% water, about 4-12% emollient oil, about 3-10% emollient wax stabilizer, about 5-20% polyhydric alcohol emollient and about 0.5-10% organic, water-soluble surfactant.
- 26. The dispensing and applicator system according to claim 1, wherein the first dermatological composition comprises an effective amount of one or more sunscreen compounds.
- 27. The dispensing and applicator system according to claim 25, wherein the second dermatological composition comprises an effective amount of one or more sunscreen compounds.
- 28. The dispensing and applicator system according to claim 1, wherein the first composition is a pigment-containing wax-based cosmetic composition and the second composition is a make-up remover composition comprising a wax-free mixture of about 25-75% water, about 15-70% of a water-insoluble liquid emollient oil and an amount of a surfactant effective to stabilize the mixture as a homogeneous emulsion.
- 29. The dispensing and applicator system according to claim 28, wherein the first applicator pad is a hydrophilic polyurethane foam pad.
- 30. The dispensing and applicator system according to claim 28, wherein the first dermatological agent is an effective dermatological amount of corticosteroid.
- 31. The dispensing and applicator system according to claim 30, wherein the corticosteroid is dispersed throughout the first applicator pad as a powder.
- 32. The dispensing and applicator system according to claim 30, wherein the first applicator pad is impregnated with a corticosteroid in combination with a pharmaceutically acceptable carrier.
- 33. The dispensing and applicator system according to claim 30, wherein the second dermatological agent is an antihistamine, an antibiotic, an antifungal agent, a sunscreen, an emollient or a film-forming polymer.
Parent Case Info
This is a division of application Ser. No. 07/986,598, filed Dec. 7, 1992, now U.S. Pat. No. 5,242,433.
US Referenced Citations (6)
Divisions (1)
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Number |
Date |
Country |
Parent |
986598 |
Dec 1992 |
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