The present invention relates to the field of signal processing. More specifically, the present invention relates to the processing of measured signals, containing a primary signal portion and a secondary signal portion, for the removal or derivation of either the primary or secondary signal portion when little is known about either of these components. The present invention is especially useful for physiological monitoring systems including blood oxygen saturation systems and pulserate measurement systems. The present invention further relates to a method and apparatus for signal processing of signals in order to compute an estimate for pulserate.
Signal processors are typically employed to remove or derive either the primary or secondary signal portion from a composite measured signal including a primary signal portion and a secondary signal portion. For example, a composite signal may contain a primary signal portion comprising desirable data and a secondary signal portion comprising noise. If the secondary signal portion occupies a different frequency spectrum than the primary signal portion, then conventional filtering techniques such as low pass, band pass, and high pass filtering are available to remove or derive either the primary or the secondary signal portion from the total signal. Fixed single or multiple notch filters could also be employed if at least one of the primary and secondary signal portions exists at a fixed frequency band.
It is often the case that an overlap in frequency spectrum between the primary and secondary signal portions exists. Complicating matters further, the statistical properties of one or both of the primary and secondary signal portions may change with time. In such cases, conventional filtering techniques are ineffective in extracting either the primary or secondary signal. If, however, a description of either the primary or secondary signal portion can be derived, correlation canceling, such as adaptive noise canceling, can be employed to remove either the primary or secondary signal portion of the signal isolating the other portion. In other words, given sufficient information about one of the signal portions, that signal portion can be extracted.
Conventional correlation cancelers, such as adaptive noise cancelers, dynamically change their transfer function to adapt to and remove portions of a composite signal. However, correlation cancelers and adaptive noise cancelers require either a secondary reference or a primary reference which correlates to either the secondary signal portion only or the primary signal portion only. For instance, for a measured signal containing noise and desirable signal, the noise can be removed with a correlation canceler if a noise reference is available. This is often the case. Although the amplitudes of the reference signals are not necessarily the same as the amplitudes of the corresponding primary or secondary signal portions, the reference signals have a frequency spectrum which is similar to that of the primary or secondary signal portions.
In many cases, nothing or very little is known about the secondary and primary signal portions. One area where measured signals comprising a primary signal portion and a secondary signal portion about which no information can easily be determined is physiological monitoring. Physiological monitoring generally involves measured signals derived from a physiological system, such as the human body. Measurements which are typically taken with physiological monitoring systems include electrocardiographs, blood pressure, blood gas saturation (such as oxygen saturation), capnographs, other blood constituent monitoring, heart rate, respiration rate, electro-encephalograph (EEG) and depth of anesthesia, for example. Other types of measurements include those which measure the pressure and quantity of a substance within the body such as cardiac output, venous oxygen saturation, arterial oxygen saturation, bilirubin, total hemoglobin, breathalyzer testing, drug testing, cholesterol testing, glucose testing, and carbon dioxide testing, protein testing, carbon monoxide testing, and other in-vivo measurements, for example. Complications arising in these measurements are often due to motion of the patient, both external and internal (muscle movement, vessel movement, and probe movement, for example), during the measurement process.
Many types of physiological measurements can be made by using the known properties of energy attenuation as a selected form of energy passes through a test medium such as a finger, shown schematically in
A blood gas monitor is one example of a physiological monitoring system which is based upon the measurement of energy attenuated by biological tissues or substances. Blood gas monitors transmit light into the test medium and measure the attenuation of the light as a function of time. The output signal of a blood gas monitor which is sensitive to the arterial blood flow contains a component having a waveform representative of the patient's arterial pulse. This type of signal, which contains a component related to the patient's pulse, is called a plethysmographic wave, and is shown in
Typically, a digit such as a finger, an ear lobe, or other portion of the body where blood flows close to the skin, is employed as the medium through which light energy is transmitted for blood gas attenuation measurements. The finger comprises skin, fat, bone, muscle, etc., as shown
An example of a more realistic measured waveform is shown in
A pulse oximeter is a type of blood gas monitor which non-invasively measures the arterial saturation of oxyten in the blood. The pumping of the heart forces freshly oxygenated blood into the arteries causing greater energy attenuation. As well understood in the art, the arterial saturation of oxygenated blood may be determined from the depth of the valleys relative to the peaks of two plethysmographic waveforms measured at separate wavelengths. Patient movement introduces motion artifacts to the composite signal as illustrated in the plethysmographic waveform illustrated in
The present invention involves several different embodiments using the novel signal model in accordance with the present invention to estimate the desired signal portion of a measured data signal where the measured data contains desired and undesired components. In one embodiment, a signal processor acquires a first measured signal and a second measured signal. The first signal comprises a desired signal portion and an undesired signal portion. The second measured signal comprises a desired signal portion and an undesired signal portion. The signals may be acquired by propagating energy through a medium and measuring an attenuated signal after transmission or reflection. Alternatively, the signals may be acquired by measuring energy generated by the medium.
In one embodiment, the desired signal portions of the first and second measured signals are approximately equal to one another, to with a first constant multiplier. The undesired signal portions of the first and second measured signals are also approximately equal to one another, to within a second constant multiplier. A scrubber coefficient may be determined, such that an estimate for the first signal can be generated by inputting the first and second measured signals, and the scrubber coefficient into a waveform scrubber. The output of the waveform scrubber is generated by multiplying the first measured signal by the scrubber coefficient and then adding the result to the second measured signal.
In one embodiment, the scrubber coefficient is determined by normalizing the first and second measured signals, and then transforming the normalized signals into a spectral domain. The spectral domain signals are then divided by one another to produce a series of spectral ratio lines. The need for waveform scrubbing can be determined by comparing the largest ratio line to the smallest ratio line. If the difference does not exceed a threshold value, the no scrubbing is needed. If the difference does exceed a threshold value, then the waveform must be scrubbed, and the scrubbing coefficient corresponds to the magnitude of the largest ratio line.
Another aspect of the present invention involves a physiological monitor having a signal processor which computes an estimate for an unknown pulserate from the measured data. In one embodiment, the signal processor receives measured data from a detector that measures a physiological property related to the heartbeat. The signal processor transforms the data into a spectral domain and then identifies a series of spectral peaks and the frequencies associated with those peaks. The signal processor then applies a set of rules to the spectral peaks and the associated frequencies in order to compute an estimate for the pulserate.
In yet another embodiment of the pulserate detector, the signal processor performs a first transform to transform the measured data into a first transform space. The signal processor then performs a second transform to transform the data from the first transform space into a second transform space. The signal processor then searches the data in the second transform space to find the pulserate.
In another embodiment, the transform into the first transform space is a spectral transform such as a Fourier transform. In another embodiment, the transform into the second transform space is a spectral transform such as a Fourier transform. In yet another embodiment, once the data has been transformed into the second transform space, the signal processor performs a 1/x mapping on the spectral coordinates before searching for the pulserate.
In another embodiment, the signal processor transforms the measured data into a first spectral domain, and then transforms the data from the first spectral domain into a second spectral domain. After twice transforming the data, the signal processor performs a 1/x remapping on the coordinates of the second spectral domain. The signal processor then searches the remapped data for the largest spectral peak corresponding to a pulserate less than 120 beats per minute. If such a peak is found, then the signal processor outputs the frequency corresponding to that peak as being the pulserate. Otherwise, the signal processor searches the data transformed into the first spectral domain for the largest spectral peak in that domain, and outputs a pulserate corresponding to the frequency of the largest peak in the first spectral domain.
In another embodiment of the pulserate detector, the signal processor first transforms the measured data into a first spectral domain. Then the signal processor takes the magnitude of the transformed data and then transforms the magnitudes into a second spectral domain. Then the signal processor then performs a 1/x mapping of the spectral coordinates. After the 1/x mapping, the signal processor feeds the transformed and remapped data into a neural network. The output of the neural network is the pulserate.
The present invention involves a system which uses first and second measured signals that each contain a primary signal portion and a secondary signal portion. In other words, given first and second composite signals c1(t)=s1(t)+n1(t) and c2(t)=s2(t)+n2(t), the system of the present invention can be used to isolate either the primary signal portion s(t) or the secondary signal portion n(t) of the two composite signals. Following processing, the output of the system provides a good approximation n″(t) to the secondary signal portion n(t) or a good approximation s″(t) to the primary signal portion s(t).
The system of the present invention is particularly useful where the primary signal portion s(t), the secondary signal portion n(t), or both, may contain one or more of a constant portion, a predictable portion, an erratic portion, a random portion, etc. The primary signal approximation s″(t) or the secondary signal approximation n″(t) is derived by removing as many of the secondary signal portions n(t) or primary signal portions s(t) from the composite signal c(t) as possible. The remaining signal forms either the primary signal approximation s″(t) or the secondary signal approximation n″(t), respectively. The constant portion and the predictable portion of the secondary signal n(t) are easily removed with traditional filtering techniques, such as simple subtraction, low pass, band pass, and high pass filtering. The erratic portion is more difficult to remove due to its unpredictable nature. If something is known about the erratic signal, even statistically, it could be removed, at least partially, from the measured signal via traditional filtering techniques. However, often no information is known about the erratic portion of the secondary signal n(t). In this case, traditional filtering techniques are usually insufficient.
In order to remove the secondary signal n(t), a signal model in accordance with the present invention is defined as follows for the first and second measured signals c1 and c2:
where s1 and n1 are at least somewhat (preferably substantially) uncorrelated and s2 and n2 are at least somewhat (preferably substantially) uncorrelated. The first and second measured signals c1 and c2 are related by correlation coefficients ra and rv as defined above. The use and selection of these coefficients is described in further detail below.
In accordance with one aspect of the present invention this signal model is used in combination with a waveform scrubber to remove the undesired portion of the measured signals.
The description that follows can best be understood in view of the following list which briefly describes how the invention is broken down and described according to the following topics:
A specific example of a physiological monitor using a processor of the present invention to determine a secondary reference n′(t) for input to a canceler that removes erratic motion-induced secondary signal portions is a pulse oximeter. Pulse oximetry may also be performed using a processor of the present invention to determine a primary signal reference s′(t) which may be used for display purposes or for input to a processor to derive information about patient movement, pulserate, and venous blood oxygen saturation.
A pulse oximeter typically causes energy to propagate through a medium where blood flows close to the surface, for example, an ear lobe, or a digit such as a finger, a forehead or a fetus' scalp. An attenuated signal is measured after propagation through or reflected from the medium. The pulse oximeter estimates the saturation of oxygenated blood.
Freshly oxygenated blood is pumped at high pressure from the heart into the arteries for use by the body. The volume of blood in the arteries and arterioles varies with the heartbeat, giving rise to a variation in absorption of energy at the rate of the heartbeat, or the pulse. The blood scatters both red and infrared light, and thus as the volume of blood changes, the amount of scattering changes as well. Typically the effects due to scattering are small when compared to the effects due to the change in blood volume.
Oxygen depleted, or deoxygenated, blood is returned to the heart by the veins along with unused oxygenated blood. The volume of blood in the veins varies with back pressure due to breathing as well as local uncontrolled motion of muscles. These variations typically occur at a rate that is much slower than the heartbeat. Thus, when there is no motion induced variation in the thickness of the veins, venous blood causes a low frequency variation in absorption of energy. When there is motion induced variation in the thickness of the veins, the scattering changes as well and this absorption is coupled with the erratic variation in absorption due to motion artifacts.
In absorption measurements using the transmission of energy through a medium, two light emitting diodes (LEDs) are positioned close to a portion of the body where blood flows close to the surface, such as a finger, and a photodetector is positioned near the LEDs. Typically, in pulse oximetry measurements, one LED emits a visible wavelength, preferably red, and the other LED emits an infrared wavelength. However, one skilled in the art will realize that other wavelength combinations, as well as combinations of more than two wavelengths, could be used. The finger comprises skin, tissue, muscle, both arterial blood and venous blood, fat, etc., each of which absorbs light energy differently due to different absorption coefficients, different concentrations, different thicknesses, and changing optical pathlengths. When the patient is not moving, absorption is substantially constant except for the flow of blood. The constant attenuation can be determined and subtracted from the signal via traditional filtering techniques. When the patient moves, this causes perturbation such as changing optical pathlength due to movement of background fluids (e.g., venous blood having a different saturation than the arterial blood). Therefore, the measured signal becomes erratic. Erratic motion induced noise typically cannot be predetermined and/or subtracted from the measured signal via traditional filtering techniques. Thus, determining the oxygen saturation of arterial blood and venous blood becomes more difficult.
The front end analog signal conditioning circuit 330 has outputs coupled to an analog to digital conversion circuit 332. The analog to digital conversion circuit 332 has outputs coupled to a digital signal processing system 334. The digital signal processing system 334 provides the desired parameters as outputs for a display 336. Outputs for display are, for example, blood oxygen saturation, heart rate, and a clean plethysmographic waveform.
The signal processing system also provides an emitter current control output 337 to a digital-to-analog converter circuit 338 which provides control information for a set of light emitter drivers 340. The light emitter drivers 340 couple to the light emitters 301, 302. The digital signal processing system 334 also provides a gain control output 343 for the front end analog signal conditioning circuitry 330.
The preferred driver depicted in
The voltage reference 324 is also chosen as a low noise DC voltage reference for the digital to analog conversion circuit 325. In addition, in the present embodiment, the voltage reference 324 has a lowpass output filter with a very low corner frequency (e.g., 1 Hz in the present embodiment). The digital to analog converter 325 also has a lowpass filter at its output with a very low corner frequency (e.g., 1 Hz). The digital to analog converter 338 provides signals for each of the emitters 301, 302.
In the present embodiment, the output of the voltage to current converters 328, 329 are switched such that with the emitters 301, 302 connected in back-to-back configuration, only one emitter is active an any given time. In addition, the voltage to current converter 328 or 329 for the inactive emitter is switched off at its input as well, such that it is completely deactivated. This reduces noise from the switching and voltage to current conversion circuitry. In the present embodiment, low noise voltage to current converters are selected (e.g., Op 27 Op Amps), and the feedback loop is configured to have a low pass filter to reduce noise. In the present embodiment, the low pass filtering function of the voltage to current converters 328, 329 has a corner frequency of just above 316.7 Hz, which is the switching speed for the emitters, as further discussed below. Accordingly, the preferred driver circuit of
In general, each of the red and infrared light emitters 301, 302 emits energy which is partially absorbed by the finger 310 and the remaining energy is received by the photodetector 320. The photodetector 320 produces an electrical signal which corresponds to the intensity of the light energy striking the photodetector 320. The front end analog signal conditioning circuitry 330 receives the intensity signals and filters and conditions these signals, as further described below, for further processing. The resultant signals are provided to the analog-to-digital conversion circuitry 332 which converts the analog signals to digital signals for further processing by the digital signal processing system 334. In the present embodiment, the output of the digital signal processing system 334 provides clean plethysmographic waveforms of the detected signals and provides values for oxygen saturation and pulse rate to the display 336.
It should be understood that in different embodiments of the present invention, one or more of the outputs may be provided. The digital signal processing system 334 also provides control for driving the light emitters 301, 302 with an emitter current control signal on the emitter current control output 337. This value is a digital value which is converted by the digital-to-analog conversion circuit 338 which provides a control signal to the emitter current drivers 340. The emitter current drivers 340 provide the appropriate current drives for the red emitter 301 and the infrared emitter 302. Further detail of the operation of the physiological monitor for pulse oximetry is explained below.
In the present embodiment, the light emitters 301, 302 are driven via the emitter current driver 340 to provide light transmission with digital modulation at 316.7 Hz. In the present embodiment, the light emitters 301, 302 are driven at a power level which provides an acceptable intensity for detection by the detector and for conditioning by the front end analog signal conditioning circuitry 330. Once this energy level is determined for a given patient by the digital signal processing system 334, the current level for the red and infrared emitters is maintained constant. It should be understood, however, that the current may be adjusted for changes in the ambient room light and other changes which would effect the voltage input to the front end analog signal conditioning circuitry 330. In the present invention, the red and infrared light emitters 301, 302 are modulated as follows: for one complete 316.7 Hz red cycle, the red emitter 301 is activated for the first quarter cycle, and off for the remaining three-quarters cycle; for one complete 316.7 Hz infrared cycle, the infrared light emitter 302 is activated for one quarter cycle and is off for the remaining three quarters cycle. In order to only receive one signal at a time, the emitters are cycled on and off alternatively, in sequence, with each only active for a quarter cycle per 316.7 Hz cycle and with a quarter cycle separating the active times.
The light signal is attenuated (amplitude modulated) by the pumping of blood through the finger 310 (or other sample medium). The attenuated (amplitude modulated) signal is detected by the photodetector 320 at the 316.7 Hz carrier frequency for the red and infrared light. Because only a single photodetector is used, the photodetector 320 receives both the red and infrared signals to form a time division multiplexed (TDM) signal. The TDM signal is provided to the front analog signal conditioning circuitry 330 and may be demodulated by either before or after analog to digital conversion.
Saturation Curves and Normalization
The ability of the apparatus 299 to measure the desired physiologic properties lies in the optical absorption properties of hemoglobin, as illustrated in
At the reference line 506, the Hb curve 503 shows more absorption than the HbO2 curve 504. Conversely, at the reference line 505, the HbO2 curve shows more absorption than the Hb curve 503. The pulse oximeter can thus measure the blood oxygen saturation by measuring absorption of the blood at 660 nm and 905 nn, and the comparing the two absorption measurements.
According to the Beer-Lambert law of absorption, the intensity of light transmitted through an absorbing medium is given by:
I=I0e−εdc (5)
where I0 is the intensity of the incident light, ε is the absorption coefficient, c is the concentration coefficient and d is the thickness of the absorbing medium. In pulse oximetry applications, there are two sources, red and infrared, and thus two incident intensities, I0,RD for red, and I0,IR for infrared. Furthermore, in blood there are two concentrations of interest, namely the concentration of oxygen poor hemoglobin, denoted by CHb and the concentration of oxygen rich hemoglobin, denoted by CHbO2. The combination of the two optical wavelengths and the two concentrations means that there are four absorption coefficients, namely εRD,Hb, εRD,HbO2, εIR,Hb, and εIR,HbO2. Using these quantities, and assuming no time variation in any of the values except d, gives two separate Beer-Lambert equations for the pulse oximeter.
IRD=I0,RD
IIR=I0,IR
The measurement apparatus 299 does not provide a capability for measuring the incident terms and I0,RD and I0,IR appearing in the above equation, and thus, strictly speaking, the value of IRD and IIR cannot be determined. However, in the pulse oximeter, only differential measurements are necessary. In other words, it is only the time varying nature of the values IRD and IIR and the relationship between the values that are important. The time variation in d(t) occurs primarily because blood flows in and out of the finger with each heartbeat. As blood flows into the finger, the effective value of d, as well as the scattering component, increases, and as blood flows out, the effective value of d and the scattering decreases. There are also time variations in the concentrations CHb and CHbO2 as the blood oxygen saturation level changes. Fortunately, these variations are slow compared to the variations in d(t), and they can be ignored.
If
The above properties of the absorption of light by Hb and HbO2 advantageously provide a way to measure blood oxygen saturation by computing the ratio of red light to infrared light.
In a preferred embodiment, the elements shown in
ln(IRD)=ln(I0,RD)−[εRD,HbCHb+εRD,HbO2CHbO2]d(t) (8)
ln(IIR)=ln(I0,IR)−[εIR,HbCHb+εIR,HbO2CHbO2]d(t) (9)
Applying a bandpass filter (in signal processing blocks 703 and 707) removes the non-time varying components, and allows Equations (8) and (9) to be rewritten as:
RD(t)=−[εRD,HbCHb+εRD,HbO2CHbO2]d(t) (10)
IR(t)=−[εIR,HbCHb+εIR,HbO2CHbO2]d(t) (11)
Detection and Removal of Motion Artifacts
Persons skilled in the art know that the data obtained during pulse oximetry measurements using red and infrared light are often contaminated due to motion. Identification and removal of these motion artifacts is often a prerequisite to any signal processing used to obtain blood oxygen saturation, pulserate, or other physiological data.
In
The correlation canceler is a complex operation requiring significant computational overhead. In accordance with one embodiment of the present invention, a new and novel method for detecting the presence of motion artifacts and removing these artifacts can be found in the spectral domain representations of the signals RD(t) and IR(t). Use of the spectral domain representations is more compatible with many of the digital signal processor (DSP) devices currently available. Further, the use of the spectral domain representations provides a method, as disclosed below, a way to estimate the amount of motion and noise separately. As a further advantage, it is noted that, under certain circumstances, the correlation canceler would drive the output signal to zero. The spectral domain method of detecting artifacts is far less likely to drive the output signal to zero.
RD(ω)=[RD(t)] (12)
is shown as a series of peaks, comprising a first spectral peak 1104 at a fundamental frequency f0, a second spectral peak 1107 at a first harmonic f1 and a third spectral peak 1110 at a frequency fm. The spectrum of IR(t), denoted mathematically as:
IR(ω)=[IR(t)] (13)
is shown as a series of peaks, comprising a first spectral peak 1103 at the fundamental frequency f0, a second spectral peak 1106 at the first harmonic f1 and a third spectral peak 1109 at a frequency fm. The ratio of the spectral components, given by RD(ω)/IR(ω), is shown as a first ratio line 1105 at the fundamental frequency f0, a second ratio line 1108 at the first harmonic f1 and a third ratio line 1111 at the frequency fm. As discussed below, when there are no motion artifacts in the spectrum of
One skilled in the art will recognize that the representations in
In an ideal measurement, the red and infrared spectra are the same to within a constant scale factor. Thus, in an ideal measurement, all of the ratio lines 1105, 1108 and 1111 have substantially the same amplitude. Any differences in the amplitude of these lines is likely due to motion or other contaminations represented by n(t) (including scattering effects). For each component, red and infrared, the model of
where S1(t) represents the infrared signal, A(t) represents the desired infrared signal and N(t) represents the noise signal. Likewise, S2(t) represents the measured red signal, r represents the ratio of red to infrared (RD(ω)/IR(ω)) expected in an uncontaminated measurement, and μ represents the ratio of red noise to infrared noise. The quantities h(t) and η(t) are primarily due to scattering, and thus required because, strictly speaking, A(t) and N(t) in the red channel and infrared channels are not simply related by a constant. However, for most purposes, the quantities h(t) and η(t) are sufficiently close to unity that they can be ignored.
Introducing an arbitrary scaling factor a into the equation for S1, and then subtracting the two equations yield (for notational convenience, the time dependence of S, A and N will not be explicitly shown):
αS1−S2=A(α−r)+N(α−μ) (15)
Two special cases arise from Equation (17). First, when α=r, Equation (17) reduces to:
Second, when α=μ, Equation (17) reduces to:
The values of μ and r can be found from the ratio of RD(ω)/IR(ω) as shown in
In a preferred embodiment, the value of μ is found by classifying the ratio peaks according to a ratio threshold g. The ratio threshold g is computed identifying the first N ratio lines RN associated with the first N spectral peaks. The ratio threshold g is then computed as a modified center of mass for the RN lines according to the following equation.
Each ratio line is then compared with the ratio threshold g. Only those ratio lines whose magnitude is larger than the ratio threshold g are included in a set Y of ratio lines. Only ratio lines in the set Y are used in the calculation of μ. In one embodiment, the value of μ is the magnitude of the largest ratio peak in the set of ratio peaks Ri for i=0 . . . N. In an alternate embodiment, the value of μ is the magnitude of the ratio peak corresponding to the largest spectral peak in the set Y.
The values of μ and r are used to determine whether motion artifacts are present. In one embodiment, the ratio μ/r is calculated. If the ratio is close to unity, then, to within a constant scaling factor, the spectrum RD(ω) is approximately the same as the spectrum IR(ω) and thus there are no motion artifacts. If, on the other hand, the ratio μ/r is not close to unity, then the shape of the spectrum RD(ω) is different from the spectrum IR(ω), signaling the presence of motion artifacts, and thus the spectrum must be scrubbed according to Equation (17).
In a preferred embodiment, a delta is computed by subtracting the magnitude of the smallest ratio line from the magnitude of the largest ratio line. If the delta is smaller than a threshold value, then the spectrum RD(ω) is approximately the same as the spectrum IR(ω) and thus there are no motion artifacts, but only variations due to scattering. If, on the other hand, the delta μ−r is greater than the threshold value, then the shape of the spectrum RD(ω) is different from the spectrum IR(ω), signaling the presence of motion artifacts, and thus the spectrum must be scrubbed according to Equation (19).
One skilled in the art will recognize that the linearity of the Fourier transform allows the scrubbing operation to be carried out in the frequency domain as well. A frequency domain scrubber 1240 is also shown in
Inside the frequency domain scrubber 1260, the terminal A is connected to a signal input of a Fourier transform block 1262. The output of the Fourier transform block 1262 is connected to a signal input of a gain controlled amplifier 1266. A gain control input of the amplifier 1266 is connected to the scrubber terminal D. The scrubber terminal B is connected to a Fourier transform block 1264. An output of the transform block 1264 is connected to a plus input of an adder 1268. An output of the amplifier 1266 is connected to a minus input of the adder 1268. An output of the adder 1268 is connected to the scrubber output terminal C.
Regardless of whether the time domain scrubber 1242 or the frequency domain scrubber 1260 is used, the scrubber output C is a plethysmographic waveform in the frequency domain at a terminal 1249. Ideally, the waveform at terminal 1249 is cleaner (e.g., has a better signal to noise ratio) than the waveform at either scrubber input A or scrubber input B. The waveform at terminal 1249 can be displayed on a display (not shown) or sent to a rule based pulserate detector 1250 and/or a transform based pulserate detector 1252.
One skilled in the art will recognize that the flowchart in
Rule Based Pulserate Detection
In addition to measuring blood oxygen saturation, a pulse oximeter is able to perform continuous monitoring of a patient's pulserate. As shown in
Often the ideal waveform of
The spectrum shown in curve 1422 is commonly seen in plethysmographic waveforms and corresponds to a frequency modulated (FM) heartbeat. In accordance with one aspect of the present invention, a rule based method for determining the pulserate of a heart producing the spectrum of
Amplitude modulation (AM) of the plethysmographic waveform is also possible and common. Amplitude modulation occurs primarily when the heart beats with different strength on different heartbeats.
In accordance with one aspect of the present invention, the pulserate can be determined in the presence of FM and AM distortions by classifying the spectrum as one of five categories grouped into three cases. The five categories are illustrated as idealized graphs in:
In accordance with one aspect of the present invention, the pulserate is determined by identifying the largest three spectral lines, then matching the spectrum to one of the idealized spectra shown by the plots 1600, 1610, 1620, 1630, or 1640, and then applying one of a set of rules to determine the pulserate. It will be understood by one skilled in the art that, although the frequencies of the spectral shown in the plots 1600, 1610, 1620, 1630, or 1640 appear to be harmonically related. In practice the spectral lines may not correspond to frequencies which are harmonics.
The details of the rule based process are shown in the flowchart of
In the process block 1812, the first three spectral peaks are sorted by magnitude, and the values assigned to variables A0, A1, and A2 such that A0 is the magnitude of the largest peak, A1 is the magnitude of the middle peak, and A is the magnitude of the smallest peak. Also, in the process block 1812, variables f0, f1, and f2, representing the frequencies corresponding to A0, A1 and A2 respectively, are set. Upon completion of the process block 1812, the process advances to a decision block 1814. In the decision block 1814, if A0 is greater than or equal to 1.2*(A1+A2) and f0 is less than 250, then the process advances to a process block 1816; otherwise the process jumps to a decision block 1824. In the process block 1816, the value of p is set to p=f0, and the process then advances to a decision block 1818. In the decision block 1818, the values of f0, f1, and f2 are checked to see if they are harmonics of one another. In a preferred embodiment, this is done by checking to see whether a frequency fi is within ten beats per minute of being a integer multiple of another frequency fj (where i,j=0, 1, or 2). If the decision block 1818 detects that the frequencies are harmonics, then the process advances to a process block 1820; otherwise, the process advances to a process block 1822. In the process block 1820, the value of σ is set to 60, and the process then advances to the decision block 1824. In the process block 1822, the value of σ is set to 50 and the process then advances to the decision block 1824.
In the decision block 1824, if A0<1.2*(A1+A2), then the process advances to a decision block 1826, otherwise the process advances to the exit block. In the decision block 1826, if (f0<f1) and (f0<f2), then the process advances to a decision block 1828; otherwise the process advances to a decision block 1938. In the decision block 1828, if the frequencies f0, f1, and f2 are harmonics, then the process advances to a decision block; otherwise, the process advances to a process block 1836. In the process block 1836, the value of p is set to p=f0, the value of σ is set to 90, and the process then advances to the decision block 1838. In the decision block 1830, if f0 is less than 45 beats per minute, then the process advances to a process block 1834; otherwise, the process advances to a process block 1832. In the process block 1832, the value of p is set to p=f0, the value of σ is set to σ=80, and the process then advances to the decision block 1838. In the process block 1834, the value of σ is set to p=(f0+f1+f2)/3, the value of σ is set to σ=70, and the process then advances to the decision block 1838.
In the decision block 1838, if f0>f1 or f0>f2, then the process advances to a decision block 1840; otherwise, the process advances to a decision block 1846. In the decision block 1840, if (f0>fi) and (f0, f1 and f2 are harmonics) and (A0<1.7A1) and (30<f1<130) then the process advances to a decision block 1842; otherwise, the process advances to a process block 1844. In the process block 1842, the value of p is set to p=f1, the value of σ is set to σ=100, and the process then advances to the decision block 1848. In the process block 1844, the value of p is set to p=f0, the value of σ is set to σ=110, and the process then advances to the decision block 1848.
In the decision block 1848, if (f0, f1 and f2, are harmonics) and f0<100 and (A1+A2)/A0>1.5), then the process advances to a process block 1852; otherwise, the process advances to a process block 1850. In the process block 1852, the value of p is set to p=(f0+f1+f2)/3, the value of σ is set to σ=120, and the process then advances to the exit block. In the process block 1852, the value of p is set to p=f0, the value of σ is set to σ=130, and the process then advances to the exit block.
As stated previously, when the process shown in
Transform Based Pulserate Detection
In accordance with another aspect of this invention, the pulserate can be determined in the presence of FM and AM distortions by using a pleth to pulserate transform (PPRT). [f(t)]. The output of the block 1702 is fed into a magnitude block 1703 which finds the magnitude of the signal F(ω). An output of the magnitude block 1703, shown as a plot 1713, is fed into a second forward Fourier transform block 1704 which transforms the signal |F(ω)| into a signal G(x) where G(x)=
[|F(ω)|] and G(x) is a complex number. The output of the block 1704 is fed into a block 1705 which extracts the real portion of G(x). The real portion of G(x) is then fed into a 1/x mapping block 1706. An output of the mapping block 1706 is fed into a pulserate detector block 1707. A pulserate output from the detector block 1706 is sent to a display 1708.
In an alternate embodiment, the magnitude block could be replaced by a block which extracts the real portion of the waveform. Likewise, the block 1705 which extracts the real portion of G(x) could be replaced by a magnitude block which extracts |G(x)|.
One skilled in the art will recognize that the output of the magnitude block 1703 is merely the absolute value of the Fourier transform of the plethysmographic wave f(t) on a point by point basis. The graph 1713 shows this signal as a series of spectral lines of varying amplitudes. In many cases, this spectrum will be similar to that shown in
The nature of the Fourier transform is to identify and quantify the periodic nature of a function. If the waveform shown in the plot 1713 were in the time domain, rather than the frequency domain, then the series of pulses (the spectral lines of the plot 1713) would correspond to a periodic train of pulses, having a fundamental frequency given by the pulse repetition frequency and modulated by the spectrum of the individual pulses. Mathematically, it does not matter that the waveform of the plot 1713 is not in the time domain. The Fourier transform can still be applied, and it will still produce a very strong spectral line corresponding to the inherent periodicity, and corresponding component strength, of the waveform.
Thus, the operation of the block 1704, in performing a forward Fourier transform on a frequency domain waveform is mathematically viable, and yields the desired data. The only unique ramification of the fact that the transformed data is already in the frequency domain rather than the time domain is the effect on the x axis. It is well known to those skilled in the art, that the forward Fourier transform maps the x axis into 1/x. This is most easily explained by noting that, normally, one would transform f(t) into F(ω). Since t=1/ω (to within a constant factor of 2π) it is clear that a 1/x mapping has occurred. In the present context, the 1/x mapping is undesirable because the data was already in the frequency domain. Thus the mapping must be undone by the process block 1706.
Once the waveform has been remapped in the process block 1707, it is a simple matter to find the desired pulserate in the process block 1707, because the pulserate will correspond to the largest spectral peak. Again, this occurs because the second Fourier transform “identifies” the dominant periodicity (e.g., the dominant string of harmonics) and collapses that periodicity into a single spectral line. The pulserate detector 1707 merely searches for the largest spectral peak and sends, to the display 1708, the frequency that corresponds to the largest peak.
In yet another embodiment, the process block 1707 looks for the existence of a spectral peak below 120 beats per minute. If a spectral peak below 120 beats per minute is found, then the frequency corresponding that peak is the pulserate. Of, on the other hand, no spectral peak below 120 beats per minute is found, then the process block 1707 finds the largest spectral peak in the original fourier spectrum that exists at the output of the Fourier transform block 1702. The pulserate is then the frequency corresponding to the largest spectral peak at the output of the Fourier transform block 1702.
In yet another embodiment, the ratio of the largest two peaks in the PPRT waveform 1716 can be used to generate a confidence factor that provides some indication of the accuracy of the computed pulserate. In a preferred embodiment, a contrast ratio is computed by dividing the magnitude of the largest peak in the PPRT waveform 1716 by the magnitude of the second largest peak in the PPRT waveform 1716. A large contrast ratio corresponds to high confidence that the computed pulserate is accurate. A contrast ratio near unity corresponds to low confidence that the computed pulserate is accurate.
Neural Network Embodiments
In yet another embodiment, much of the signal processing can be accomplished by a neural network. One skilled in the art will recognize that the signal processing associated with the removal of motion artifacts involves non-linear and linear processes. The frequency domain waveform scrubber 1260 and the time domain waveform scrubber 1242 are both linear processes. However, the calculation of α in
One skilled in the art will appreciate that other non-linear filtering processes can be used. In particular, any of these non-linear processes can be performed by a neural network as shown in
The front end analog signal conditioning circuit 330 has outputs coupled to an analog to digital conversion circuit 332. The analog to digital conversion circuit 332 has outputs coupled to a digital signal processing and neural network signal extraction system 1934. The signal processing system 1934 provides the desired parameters as outputs for a display 336. Outputs for display are, for example, blood oxygen saturation, heart rate, and a clean plethysmographic waveform.
The signal processing system also provides an emitter current control output 337 to a digital-to-analog converter circuit 338 which provides control information for a set of light emitter drivers 340. The light emitter drivers 340 couple to the light emitters 301, 302. The signal processing system 1934 also provides a gain control output 343 for the front end analog signal conditioning circuitry 330.
Additional Embodiments
While one embodiment of a physiological monitor incorporating a processor of the present invention for determining a reference signal for use in a waveform scrubber, to remove or derive primary and secondary components from a physiological measurement has been described in the form of a pulse oximeter, it will be obvious to one skilled in the art that other types of physiological monitors may also employ the above described techniques.
In particular, one skilled in the art will recognize that in all cases, the Fourier transform disclosed above can be replaced by a Fast Fourier Transform (FFT), a Chirp-Z Transform, a wavelet transform, a discrete Fourier transform, or any other operation that produces the same or similar result.
Furthermore, the signal processing techniques described in the present invention may be used to compute the arterial and venous blood oxygen saturations of a physiological system on a continuous or nearly continuous time basis. These calculations may be performed, regardless of whether or not the physiological system undergoes voluntary motion.
Furthermore, it will be understood that transformations of measured signals other than logarithmic conversion and that the determination of a proportionality factor which allows removal or derivation of the primary or secondary signal portions for determination of a reference signal are possible. Additionally, although the proportionality factor r has been described herein as a ratio of a portion of a first signal to a portion of a second signal, a similar proportionality constant determined as a ratio of a portion of a second signal to a portion of a first signal could equally well be utilized in the processor of the present invention. In the latter case, a secondary reference signal would generally resemble n′(t)=nb(t)−rna(t).
One skilled in the art will realize that many different types of physiological monitors may employ the teachings of the present invention. Other types of physiological monitors include, but are in not limited to, electro-cardiographs, blood pressure monitors, blood constituent monitors (other than oxygen saturation) monitors, capnographs, heart rate monitors, respiration monitors, or depth of anesthesia monitors. Additionally, monitors which measure the pressure and quantity of a substance within the body such as a breathalyzer, a drug monitor, a cholesterol monitor, a glucose monitor, a carbon dioxide monitor, a glucose monitor, or a carbon monoxide monitor may also employ the above described techniques.
Furthermore, one skilled in the art will recognize that many of the signal processing techniques, and many of the filters disclosed herein are classification techniques. Many of the classification mechanisms herein involve classification of spectral lines and ratios of various spectral lines. Other classification schemes are possible within the spirit and scope of the invention.
Furthermore, one skilled in the art will realize that the above described techniques of primary or secondary signal removal or derivation from a composite signal including both primary and secondary components can also be performed on electrocardiography (ECG) signals which are derived from positions on the body which are close and highly correlated to each other.
Furthermore, one skilled in the art will realize that the above described techniques can also be performed on signals made up of reflected energy, rather than transmitted energy. One skilled in the art will also realize that a primary or secondary portion of a measured signal of any type of energy, including but not limited to sound energy, X-ray energy, gamma ray energy, or light energy can be estimated by the techniques described above. Thus, one skilled in the art will realize that the techniques of the present invention can be applied in such monitors as those using ultrasound where a signal is transmitted through a portion of the body and reflected back from within the body back through this portion of the body. Additionally, monitors such as echo-cardiographs may also utilize the techniques of the present invention since they too rely on transmission and reflection.
While the present invention has been described in terms of a physiological monitor, one skilled in the art will realize that the signal processing techniques of the present invention can be applied in many areas, including but not limited to the processing of a physiological signal. The present invention may be applied in any situation where a signal processor comprising a detector receives a first signal which includes a first primary signal portion and a first secondary signal portion and a second signal which includes a second primary signal portion and a second secondary signal portion. Thus, the signal processor of the present invention is readily applicable to numerous signal processing areas.
This application is a continuation of U.S. application Ser. No. 11/842,128, filed on Aug. 20, 2007, which is a continuation of U.S. application Ser. No. 10/791,683, filed on Mar. 2, 2004, which is a continuation of U.S. application Ser. No. 09/547,588, filed Apr. 11, 2000 (now U.S. Pat. No. 6,699,194), which is a continuation of U.S. application Ser. No. 09/081,539, filed May 19, 1998 (now U.S. Pat. No. 6,067,462), which is a divisional of U.S. application Ser. No. 08/834,194, filed Apr. 14, 1997 (now U.S. Pat. No. 6,002,952). The present application incorporates the foregoing disclosures herein by reference.
Number | Name | Date | Kind |
---|---|---|---|
3638640 | Shaw | Feb 1972 | A |
3647299 | Lavallee | Mar 1972 | A |
3659591 | Doll et al. | May 1972 | A |
3704706 | Herczfeld et al. | Dec 1972 | A |
3991277 | Hirata | Nov 1976 | A |
3998550 | Konishi et al. | Dec 1976 | A |
4051522 | Healy | Sep 1977 | A |
4063551 | Sweeney | Dec 1977 | A |
4085378 | Ryan | Apr 1978 | A |
4086915 | Kofsky et al. | May 1978 | A |
4095117 | Nagy | Jun 1978 | A |
4129124 | Thalmann | Dec 1978 | A |
4167331 | Nielsen | Sep 1979 | A |
4197836 | Wagner et al. | Apr 1980 | A |
4238746 | McCool et al. | Dec 1980 | A |
4243935 | McCool et al. | Jan 1981 | A |
4266554 | Hamaguri | May 1981 | A |
4305398 | Sawa | Dec 1981 | A |
4308456 | Van Der Gaag et al. | Dec 1981 | A |
4407290 | Wilber | Oct 1983 | A |
4446871 | Imura | May 1984 | A |
4519396 | Epstein et al. | May 1985 | A |
4537200 | Widrow | Aug 1985 | A |
4586513 | Hamaguri | May 1986 | A |
4617589 | Weckenbrock | Oct 1986 | A |
4623248 | Sperinde | Nov 1986 | A |
4649505 | Zinser, Jr. et al. | Mar 1987 | A |
4653498 | New, Jr. et al. | Mar 1987 | A |
4660151 | Chipman et al. | Apr 1987 | A |
4694833 | Hamaguri | Sep 1987 | A |
4714341 | Hamaguri et al. | Dec 1987 | A |
4723294 | Taguchi | Feb 1988 | A |
4745398 | Abel | May 1988 | A |
4751931 | Briller et al. | Jun 1988 | A |
4765340 | Sakai | Aug 1988 | A |
4773422 | Isaacson et al. | Sep 1988 | A |
4781200 | Baker | Nov 1988 | A |
4793361 | DuFault | Dec 1988 | A |
4799493 | DuFault | Jan 1989 | A |
4800495 | Smith | Jan 1989 | A |
4802486 | Goodman et al. | Feb 1989 | A |
4807631 | Hersh et al. | Feb 1989 | A |
4819646 | Cheung et al. | Apr 1989 | A |
4819752 | Zelin | Apr 1989 | A |
4824242 | Frick et al. | Apr 1989 | A |
4846183 | Martin | Jul 1989 | A |
4848901 | Hood, Jr. | Jul 1989 | A |
4854699 | Edgar, Jr. | Aug 1989 | A |
4858199 | Griffith | Aug 1989 | A |
4859056 | Prosser et al. | Aug 1989 | A |
4859057 | Taylor et al. | Aug 1989 | A |
4860759 | Kahn et al. | Aug 1989 | A |
4863265 | Flower et al. | Sep 1989 | A |
4867165 | Noller et al. | Sep 1989 | A |
4867571 | Frick et al. | Sep 1989 | A |
4869253 | Craig, Jr. et al. | Sep 1989 | A |
4869254 | Stone et al. | Sep 1989 | A |
4870558 | Luce | Sep 1989 | A |
4870588 | Merhav | Sep 1989 | A |
4883353 | Hausman et al. | Nov 1989 | A |
4883356 | deMey, II | Nov 1989 | A |
4892101 | Cheung et al. | Jan 1990 | A |
4897162 | Lewandowski et al. | Jan 1990 | A |
4907594 | Muz | Mar 1990 | A |
4911167 | Corenman et al. | Mar 1990 | A |
4913150 | Cheung et al. | Apr 1990 | A |
4927264 | Shiga et al. | May 1990 | A |
4928692 | Goodman et al. | May 1990 | A |
4934372 | Corenman et al. | Jun 1990 | A |
4942877 | Sakai et al. | Jul 1990 | A |
4948248 | Lehman | Aug 1990 | A |
4949710 | Dorsett et al. | Aug 1990 | A |
4951680 | Kirk et al. | Aug 1990 | A |
4955379 | Hall | Sep 1990 | A |
4956867 | Zurek et al. | Sep 1990 | A |
4960126 | Conlon et al. | Oct 1990 | A |
4960128 | Gordon et al. | Oct 1990 | A |
4964408 | Hink et al. | Oct 1990 | A |
4965840 | Subbarao | Oct 1990 | A |
4967571 | Sporri | Nov 1990 | A |
5003252 | Nystrom | Mar 1991 | A |
5003977 | Suzuki et al. | Apr 1991 | A |
RE33643 | Isaacson | Jul 1991 | E |
5041187 | Hink et al. | Aug 1991 | A |
5042499 | Frank et al. | Aug 1991 | A |
5054495 | Uemura et al. | Oct 1991 | A |
5057695 | Hirao et al. | Oct 1991 | A |
5069213 | Polczynski | Dec 1991 | A |
5078136 | Stone et al. | Jan 1992 | A |
5163438 | Gordon et al. | Nov 1992 | A |
5170791 | Boos | Dec 1992 | A |
5188108 | Secker | Feb 1993 | A |
5190038 | Polson | Mar 1993 | A |
5190047 | Odagiri et al. | Mar 1993 | A |
5193124 | Subbarao | Mar 1993 | A |
5218962 | Mannheimer | Jun 1993 | A |
5226417 | Swedlow | Jul 1993 | A |
5246002 | Prosser | Sep 1993 | A |
5259381 | Cheung et al. | Nov 1993 | A |
5270942 | Reed | Dec 1993 | A |
5273036 | Kronberg et al. | Dec 1993 | A |
5285784 | Seeker | Feb 1994 | A |
5297548 | Pologe | Mar 1994 | A |
5299120 | Kaestle | Mar 1994 | A |
5307284 | Brunfeldt | Apr 1994 | A |
5308919 | Minnich | May 1994 | A |
5319355 | Russek | Jun 1994 | A |
5331394 | Shalon et al. | Jul 1994 | A |
5337744 | Branigan | Aug 1994 | A |
5341805 | Stavridi et al. | Aug 1994 | A |
5345510 | Singhi | Sep 1994 | A |
5349952 | McCarthy et al. | Sep 1994 | A |
5353356 | Waugh et al. | Oct 1994 | A |
5355880 | Thomas et al. | Oct 1994 | A |
5355882 | Ukawa | Oct 1994 | A |
5357965 | Hall et al. | Oct 1994 | A |
5368224 | Richardson | Nov 1994 | A |
D353195 | Savage et al. | Dec 1994 | S |
D353196 | Savage et al. | Dec 1994 | S |
5377676 | Vari et al. | Jan 1995 | A |
5384451 | Smith et al. | Jan 1995 | A |
5398003 | Heyl et al. | Mar 1995 | A |
5398680 | Polson et al. | Mar 1995 | A |
5404003 | Smith | Apr 1995 | A |
5406952 | Barnes | Apr 1995 | A |
D359546 | Savage et al. | Jun 1995 | S |
5421329 | Casciani | Jun 1995 | A |
5431170 | Mathews | Jul 1995 | A |
D361840 | Savage et al. | Aug 1995 | S |
5438983 | Falcone | Aug 1995 | A |
5442940 | Secker | Aug 1995 | A |
D362063 | Savage et al. | Sep 1995 | S |
5448991 | Polson | Sep 1995 | A |
5452717 | Branigan et al. | Sep 1995 | A |
D363120 | Savage et al. | Oct 1995 | S |
5456252 | Vari et al. | Oct 1995 | A |
5458128 | Pulanyi et al. | Oct 1995 | A |
RE35122 | Corenman et al. | Dec 1995 | E |
5479934 | Imran | Jan 1996 | A |
5481620 | Vaidyanathan | Jan 1996 | A |
5482036 | Diab et al. | Jan 1996 | A |
5490505 | Diab et al. | Feb 1996 | A |
5494032 | Robinson et al. | Feb 1996 | A |
5494043 | O'Sullivan et al. | Feb 1996 | A |
5503148 | Pologe | Apr 1996 | A |
5515169 | Cargill et al. | May 1996 | A |
5533511 | Kaspari et al. | Jul 1996 | A |
5534851 | Russek | Jul 1996 | A |
5542421 | Erdman | Aug 1996 | A |
5549111 | Wright et al. | Aug 1996 | A |
5557284 | Hartman | Sep 1996 | A |
5561275 | Savage et al. | Oct 1996 | A |
5562002 | Lalin | Oct 1996 | A |
5575284 | Athan et al. | Nov 1996 | A |
5588427 | Tien | Dec 1996 | A |
5588435 | Weng et al. | Dec 1996 | A |
5590649 | Caro et al. | Jan 1997 | A |
5602924 | Durand et al. | Feb 1997 | A |
5632272 | Diab et al. | May 1997 | A |
5638816 | Kiani-Azarbayjany et al. | Jun 1997 | A |
5638818 | Diab et al. | Jun 1997 | A |
5645440 | Tobler et al. | Jul 1997 | A |
5652566 | Lambert | Jul 1997 | A |
5662105 | Tien | Sep 1997 | A |
5685299 | Diab et al. | Nov 1997 | A |
5704365 | Albrecht et al. | Jan 1998 | A |
5720293 | Quinn | Feb 1998 | A |
D393830 | Tobler et al. | Apr 1998 | S |
5738104 | Lo et al. | Apr 1998 | A |
5743262 | Lepper, Jr. et al. | Apr 1998 | A |
5758644 | Diab et al. | Jun 1998 | A |
5760910 | Lepper, Jr. et al. | Jun 1998 | A |
5769785 | Diab et al. | Jun 1998 | A |
5782237 | Casciani | Jul 1998 | A |
5782757 | Diab et al. | Jul 1998 | A |
5785659 | Caro et al. | Jul 1998 | A |
5791347 | Flaherty et al. | Aug 1998 | A |
5800348 | Kaestle | Sep 1998 | A |
5807267 | Bryars | Sep 1998 | A |
5810734 | Caro et al. | Sep 1998 | A |
5823950 | Diab et al. | Oct 1998 | A |
5830131 | Caro et al. | Nov 1998 | A |
5830137 | Scharf | Nov 1998 | A |
5833618 | Caro et al. | Nov 1998 | A |
5842979 | Jarman | Dec 1998 | A |
5842981 | Larsen et al. | Dec 1998 | A |
5853364 | Baker, Jr. et al. | Dec 1998 | A |
5860919 | Kiani-Azarbayjany et al. | Jan 1999 | A |
5865736 | Baker, Jr. | Feb 1999 | A |
5890929 | Mills et al. | Apr 1999 | A |
5891023 | Lynn | Apr 1999 | A |
5904654 | Wohltmann et al. | May 1999 | A |
5919134 | Diab | Jul 1999 | A |
5921921 | Potratz | Jul 1999 | A |
5934277 | Mortz | Aug 1999 | A |
5934925 | Tobler et al. | Aug 1999 | A |
5940182 | Lepper, Jr. et al. | Aug 1999 | A |
5950139 | Korycan | Sep 1999 | A |
5987343 | Kinast | Nov 1999 | A |
5995855 | Kiani et al. | Nov 1999 | A |
5997343 | Mills et al. | Dec 1999 | A |
6002952 | Diab et al. | Dec 1999 | A |
6011986 | Diab et al. | Jan 2000 | A |
6027452 | Flaherty et al. | Feb 2000 | A |
6036642 | Diab et al. | Mar 2000 | A |
6045509 | Caro et al. | Apr 2000 | A |
6047203 | Sackner | Apr 2000 | A |
6064910 | Andersson | May 2000 | A |
6067462 | Diab et al. | May 2000 | A |
6081735 | Diab et al. | Jun 2000 | A |
6083172 | Baker, Jr. | Jul 2000 | A |
6088607 | Diab et al. | Jul 2000 | A |
6110522 | Lepper, Jr. et al. | Aug 2000 | A |
6119026 | McNulty | Sep 2000 | A |
6122535 | Kaestle | Sep 2000 | A |
6124597 | Shehada | Sep 2000 | A |
6128521 | Marro et al. | Oct 2000 | A |
6129675 | Jay | Oct 2000 | A |
6135952 | Coetzee | Oct 2000 | A |
6144868 | Parker | Nov 2000 | A |
6151516 | Kiani-Azarbayjany et al. | Nov 2000 | A |
6152754 | Gerhardt et al. | Nov 2000 | A |
6157850 | Diab et al. | Dec 2000 | A |
6165005 | Mills et al. | Dec 2000 | A |
6184521 | Coffin, IV et al. | Feb 2001 | B1 |
6188407 | Smith | Feb 2001 | B1 |
6206830 | Diab et al. | Mar 2001 | B1 |
6229856 | Diab et al. | May 2001 | B1 |
6232609 | Snyder et al. | May 2001 | B1 |
6236872 | Diab et al. | May 2001 | B1 |
6241683 | Macklem et al. | Jun 2001 | B1 |
6253097 | Aronow et al. | Jun 2001 | B1 |
6256523 | Diab et al. | Jul 2001 | B1 |
6263222 | Diab et al. | Jul 2001 | B1 |
6278522 | Lepper, Jr. et al. | Aug 2001 | B1 |
6280213 | Tobler et al. | Aug 2001 | B1 |
6285896 | Tobler et al. | Sep 2001 | B1 |
6301493 | Marro et al. | Oct 2001 | B1 |
6317627 | Ennen et al. | Nov 2001 | B1 |
6321100 | Parker | Nov 2001 | B1 |
6325761 | Jay | Dec 2001 | B1 |
6330468 | Scharf | Dec 2001 | B1 |
6334065 | Al-Ali et al. | Dec 2001 | B1 |
6343224 | Parker | Jan 2002 | B1 |
6349228 | Kiani et al. | Feb 2002 | B1 |
6360114 | Diab et al. | Mar 2002 | B1 |
6368283 | Xu et al. | Apr 2002 | B1 |
6371921 | Caro et al. | Apr 2002 | B1 |
6377829 | Al-Ali | Apr 2002 | B1 |
6388240 | Schulz et al. | May 2002 | B2 |
6397091 | Diab et al. | May 2002 | B2 |
6411833 | Baker, Jr. et al. | Jun 2002 | B1 |
6430437 | Marro | Aug 2002 | B1 |
6430525 | Weber et al. | Aug 2002 | B1 |
6438399 | Kurth | Aug 2002 | B1 |
6463311 | Diab | Oct 2002 | B1 |
6470199 | Kopotic et al. | Oct 2002 | B1 |
6501975 | Diab et al. | Dec 2002 | B2 |
6505059 | Kollias et al. | Jan 2003 | B1 |
6515273 | Al-Ali | Feb 2003 | B2 |
6519486 | Edgar, Jr. | Feb 2003 | B1 |
6519487 | Parker | Feb 2003 | B1 |
6525386 | Mills et al. | Feb 2003 | B1 |
6526300 | Kiani et al. | Feb 2003 | B1 |
6541756 | Schulz et al. | Apr 2003 | B2 |
6542764 | Al-Ali et al. | Apr 2003 | B1 |
6580086 | Schulz et al. | Jun 2003 | B1 |
6584336 | Ali et al. | Jun 2003 | B1 |
6595316 | Cybulski et al. | Jul 2003 | B2 |
6597932 | Tian et al. | Jul 2003 | B2 |
6597933 | Kiani et al. | Jul 2003 | B2 |
6606511 | Ali et al. | Aug 2003 | B1 |
6631281 | Kastle | Oct 2003 | B1 |
6632181 | Flaherty et al. | Oct 2003 | B2 |
6639668 | Trepagnier | Oct 2003 | B1 |
6640116 | Diab | Oct 2003 | B2 |
6643530 | Diab et al. | Nov 2003 | B2 |
6650917 | Diab et al. | Nov 2003 | B2 |
6654623 | Kastle | Nov 2003 | B1 |
6654624 | Diab et al. | Nov 2003 | B2 |
6658276 | Pishney et al. | Dec 2003 | B2 |
6661161 | Lanzo et al. | Dec 2003 | B1 |
6671531 | Al-Ali et al. | Dec 2003 | B2 |
6678543 | Diab et al. | Jan 2004 | B2 |
6684090 | Ali et al. | Jan 2004 | B2 |
6684091 | Parker | Jan 2004 | B2 |
6697656 | Al-Ali | Feb 2004 | B1 |
6697657 | Shehada et al. | Feb 2004 | B1 |
6697658 | Al-Ali | Feb 2004 | B2 |
RE38476 | Diab et al. | Mar 2004 | E |
6699194 | Diab et al. | Mar 2004 | B1 |
6714804 | Al-Ali et al. | Mar 2004 | B2 |
RE38492 | Diab et al. | Apr 2004 | E |
6721582 | Trepagnier et al. | Apr 2004 | B2 |
6721584 | Baker et al. | Apr 2004 | B2 |
6721585 | Parker | Apr 2004 | B1 |
6725074 | Kastle | Apr 2004 | B1 |
6725075 | Al-Ali | Apr 2004 | B2 |
6728560 | Kollias et al. | Apr 2004 | B2 |
6735459 | Parker | May 2004 | B2 |
6745060 | Diab et al. | Jun 2004 | B2 |
6760607 | Al-All | Jul 2004 | B2 |
6770028 | Ali et al. | Aug 2004 | B1 |
6771994 | Kiani et al. | Aug 2004 | B2 |
6792300 | Diab et al. | Sep 2004 | B1 |
6813511 | Diab et al. | Nov 2004 | B2 |
6816741 | Diab | Nov 2004 | B2 |
6822564 | Al-Ali | Nov 2004 | B2 |
6826419 | Diab et al. | Nov 2004 | B2 |
6830711 | Mills et al. | Dec 2004 | B2 |
6850787 | Weber et al. | Feb 2005 | B2 |
6850788 | Al-Ali | Feb 2005 | B2 |
6852083 | Caro et al. | Feb 2005 | B2 |
6861639 | Al-Ali | Mar 2005 | B2 |
6898452 | Al-Ali et al. | May 2005 | B2 |
6920345 | Al-Ali et al. | Jul 2005 | B2 |
6931268 | Kiani-Azarbayjany et al. | Aug 2005 | B1 |
6934570 | Kiani et al. | Aug 2005 | B2 |
6939305 | Flaherty et al. | Sep 2005 | B2 |
6943348 | Coffin, IV | Sep 2005 | B1 |
6950687 | Al-Ali | Sep 2005 | B2 |
6961598 | Diab | Nov 2005 | B2 |
6970792 | Diab | Nov 2005 | B1 |
6979812 | Al-Ali | Dec 2005 | B2 |
6985764 | Mason et al. | Jan 2006 | B2 |
6993371 | Kiani et al. | Jan 2006 | B2 |
6996427 | Ali et al. | Feb 2006 | B2 |
6999904 | Weber et al. | Feb 2006 | B2 |
7003338 | Weber et al. | Feb 2006 | B2 |
7003339 | Diab et al. | Feb 2006 | B2 |
7015451 | Dalke et al. | Mar 2006 | B2 |
7024233 | Ali et al. | Apr 2006 | B2 |
7027849 | Al-Ali | Apr 2006 | B2 |
7030749 | Al-Ali | Apr 2006 | B2 |
7039449 | Al-Ali | May 2006 | B2 |
7041060 | Flaherty et al. | May 2006 | B2 |
7044918 | Diab | May 2006 | B2 |
7067893 | Mills et al. | Jun 2006 | B2 |
7096052 | Mason et al. | Aug 2006 | B2 |
7096054 | Abdul-Hafiz et al. | Aug 2006 | B2 |
7132641 | Schulz et al. | Nov 2006 | B2 |
7142901 | Kiani et al. | Nov 2006 | B2 |
7149561 | Diab | Dec 2006 | B2 |
7186966 | Al-Ali | Mar 2007 | B2 |
7190261 | Al-Ali | Mar 2007 | B2 |
7215984 | Diab | May 2007 | B2 |
7215986 | Diab | May 2007 | B2 |
7221971 | Diab | May 2007 | B2 |
7225006 | Al-Ali et al. | May 2007 | B2 |
7225007 | Al-Ali | May 2007 | B2 |
RE39672 | Shehada et al. | Jun 2007 | E |
7239905 | Kiani-Azarbayjany et al. | Jul 2007 | B2 |
7245953 | Parker | Jul 2007 | B1 |
7254429 | Schurman et al. | Aug 2007 | B2 |
7254431 | Al-Ali | Aug 2007 | B2 |
7254433 | Diab et al. | Aug 2007 | B2 |
7254434 | Schulz et al. | Aug 2007 | B2 |
7272425 | Al-Ali | Sep 2007 | B2 |
7274955 | Kiani et al. | Sep 2007 | B2 |
D554263 | Al-Ali et al. | Oct 2007 | S |
7280858 | Al-Ali et al. | Oct 2007 | B2 |
7289835 | Mansfield et al. | Oct 2007 | B2 |
7292883 | De Felice et al. | Nov 2007 | B2 |
7295866 | Al-Ali | Nov 2007 | B2 |
7328053 | Diab et al. | Feb 2008 | B1 |
7332784 | Mills et al. | Feb 2008 | B2 |
7340287 | Mason et al. | Mar 2008 | B2 |
7341559 | Schulz et al. | Mar 2008 | B2 |
7343186 | Lamego et al. | Mar 2008 | B2 |
D566282 | Al-Ali et al. | Apr 2008 | S |
7355512 | Al-Ali | Apr 2008 | B1 |
7356365 | Schurman | Apr 2008 | B2 |
7371981 | Abdul-Hafiz | May 2008 | B2 |
7373193 | Al-Ali et al. | May 2008 | B2 |
7373194 | Weber et al. | May 2008 | B2 |
7376453 | Diab et al. | May 2008 | B1 |
7377794 | Al-Ali et al. | May 2008 | B2 |
7377899 | Weber et al. | May 2008 | B2 |
7383070 | Diab et al. | Jun 2008 | B2 |
7415297 | Al-Ali et al. | Aug 2008 | B2 |
7428432 | Ali et al. | Sep 2008 | B2 |
7438683 | Al-Ali et al. | Oct 2008 | B2 |
7440787 | Diab | Oct 2008 | B2 |
7454240 | Diab et al. | Nov 2008 | B2 |
7467002 | Weber et al. | Dec 2008 | B2 |
7469157 | Diab et al. | Dec 2008 | B2 |
7471969 | Diab et al. | Dec 2008 | B2 |
7471971 | Diab et al. | Dec 2008 | B2 |
7483729 | Al-Ali et al. | Jan 2009 | B2 |
7483730 | Diab et al. | Jan 2009 | B2 |
7489958 | Diab et al. | Feb 2009 | B2 |
7496391 | Diab et al. | Feb 2009 | B2 |
7496393 | Diab et al. | Feb 2009 | B2 |
D587657 | Al-Ali et al. | Mar 2009 | S |
7499741 | Diab et al. | Mar 2009 | B2 |
7499835 | Weber et al. | Mar 2009 | B2 |
7500950 | Al-Ali et al. | Mar 2009 | B2 |
7509154 | Diab et al. | Mar 2009 | B2 |
7509494 | Al-Ali | Mar 2009 | B2 |
7510849 | Schurman et al. | Mar 2009 | B2 |
7526328 | Diab et al. | Apr 2009 | B2 |
7530942 | Diab | May 2009 | B1 |
7530949 | Al Ali et al. | May 2009 | B2 |
7530955 | Diab et al. | May 2009 | B2 |
7563110 | Al-Ali et al. | Jul 2009 | B2 |
7596398 | Al-Ali et al. | Sep 2009 | B2 |
7618375 | Flaherty | Nov 2009 | B2 |
D606659 | Kiani et al. | Dec 2009 | S |
7647083 | Al-Ali et al. | Jan 2010 | B2 |
D609193 | Al-Ali et al. | Feb 2010 | S |
D614305 | Al-Ali et al. | Apr 2010 | S |
RE41317 | Parker | May 2010 | E |
7729733 | Al-Ali et al. | Jun 2010 | B2 |
7734320 | Al-Ali | Jun 2010 | B2 |
7761127 | Al-Ali et al. | Jul 2010 | B2 |
7761128 | Al-Ali et al. | Jul 2010 | B2 |
7764982 | Dalke et al. | Jul 2010 | B2 |
D621516 | Kiani et al. | Aug 2010 | S |
7791155 | Diab | Sep 2010 | B2 |
7801581 | Diab | Sep 2010 | B2 |
7822452 | Schurman et al. | Oct 2010 | B2 |
RE41912 | Parker | Nov 2010 | E |
7844313 | Kiani et al. | Nov 2010 | B2 |
7844314 | Al-Ali | Nov 2010 | B2 |
7844315 | Al-Ali | Nov 2010 | B2 |
7865222 | Weber et al. | Jan 2011 | B2 |
7873497 | Weber et al. | Jan 2011 | B2 |
7880606 | Al-Ali | Feb 2011 | B2 |
7880626 | Al-Ali et al. | Feb 2011 | B2 |
7891355 | Al-Ali et al. | Feb 2011 | B2 |
7894868 | Al-Ali et al. | Feb 2011 | B2 |
7899507 | Al-Ali et al. | Mar 2011 | B2 |
7899518 | Trepagnier et al. | Mar 2011 | B2 |
7904132 | Weber et al. | Mar 2011 | B2 |
7909772 | Popov et al. | Mar 2011 | B2 |
7910875 | Al-Ali | Mar 2011 | B2 |
7919713 | Al-Ali et al. | Apr 2011 | B2 |
7937128 | Al-Ali | May 2011 | B2 |
7937129 | Mason et al. | May 2011 | B2 |
7937130 | Diab et al. | May 2011 | B2 |
7941199 | Kiani | May 2011 | B2 |
7951086 | Flaherty et al. | May 2011 | B2 |
7957780 | Lamego et al. | Jun 2011 | B2 |
7962188 | Kiani et al. | Jun 2011 | B2 |
7962190 | Diab et al. | Jun 2011 | B1 |
7976472 | Kiani | Jul 2011 | B2 |
7988637 | Diab | Aug 2011 | B2 |
7990382 | Kiani | Aug 2011 | B2 |
7991446 | Ali et al. | Aug 2011 | B2 |
8000761 | Al-Ali | Aug 2011 | B2 |
8008088 | Bellott et al. | Aug 2011 | B2 |
RE42753 | Kiani-Azarbayjany et al. | Sep 2011 | E |
8019400 | Diab et al. | Sep 2011 | B2 |
8028701 | Al-Ali et al. | Oct 2011 | B2 |
8029765 | Bellott et al. | Oct 2011 | B2 |
8036728 | Diab et al. | Oct 2011 | B2 |
8046040 | Ali et al. | Oct 2011 | B2 |
8046041 | Diab et al. | Oct 2011 | B2 |
8046042 | Diab et al. | Oct 2011 | B2 |
8048040 | Kiani | Nov 2011 | B2 |
8050728 | Al-Ali et al. | Nov 2011 | B2 |
RE43169 | Parker | Feb 2012 | E |
8118620 | Al-Ali et al. | Feb 2012 | B2 |
8126528 | Diab et al. | Feb 2012 | B2 |
8128572 | Diab et al. | Mar 2012 | B2 |
8130105 | Al-Ali et al. | Mar 2012 | B2 |
8145287 | Diab et al. | Mar 2012 | B2 |
8150487 | Diab et al. | Apr 2012 | B2 |
8175672 | Parker | May 2012 | B2 |
8180420 | Diab et al. | May 2012 | B2 |
8182443 | Kiani | May 2012 | B1 |
8185180 | Diab et al. | May 2012 | B2 |
8190223 | Al-Ali et al. | May 2012 | B2 |
8190227 | Diab et al. | May 2012 | B2 |
8203438 | Kiani et al. | Jun 2012 | B2 |
20020077536 | Diab et al. | Jun 2002 | A1 |
20020082488 | Al-Ali | Jun 2002 | A1 |
20020128544 | Diab et al. | Sep 2002 | A1 |
20020161291 | Kianl | Oct 2002 | A1 |
20030000522 | Lynn | Jan 2003 | A1 |
20030018241 | Mannheimer | Jan 2003 | A1 |
20030073890 | Hanna | Apr 2003 | A1 |
20030120164 | Nielsen | Jun 2003 | A1 |
20040068164 | Diab et al. | Apr 2004 | A1 |
20040204637 | Diab et al. | Oct 2004 | A1 |
20050096517 | Diab et al. | May 2005 | A1 |
20050209517 | Diab et al. | Sep 2005 | A1 |
20060200016 | Diab et al. | Sep 2006 | A1 |
20060217609 | Diab et al. | Sep 2006 | A1 |
20070225581 | Diab et al. | Sep 2007 | A1 |
20070249918 | Diab et al. | Oct 2007 | A1 |
20070291832 | Diab et al. | Dec 2007 | A1 |
20080004514 | Diab et al. | Jan 2008 | A1 |
Number | Date | Country |
---|---|---|
3328862 | Feb 1985 | DE |
102 816 | Mar 1984 | EP |
0352923 | Jan 1990 | EP |
0104771 | May 1990 | EP |
0645117 | Mar 1995 | EP |
0659384 | Jun 1995 | EP |
0 744 154 | Nov 1996 | EP |
0 760 223 | May 1997 | EP |
0 761 159 | Sep 1999 | EP |
2 075 668 | Nov 1981 | GB |
2 156 997 | Oct 1985 | GB |
2 166 326 | Apr 1986 | GB |
2 235 288 | Feb 1991 | GB |
58-065137 | Apr 1983 | JP |
WO 8403032 | Aug 1984 | WO |
WO 9211803 | Jul 1992 | WO |
WO 9215955 | Sep 1992 | WO |
WO 9220273 | Nov 1992 | WO |
WO 9409698 | May 1994 | WO |
WO 9521567 | Aug 1995 | WO |
WO 9843071 | Oct 1998 | WO |
Entry |
---|
“A More Reliable Approach for Deriving SpO2 and Pulse Rate,” Agilent Technologies, Aug. 2000, pp. 1-2. |
“FAST-Sp02 Motion-tolerant pulse oximetry with maximum sensor flexibility,” Phillips Medical Systems, pp. 1-2, 2003. |
“Product Information FAST-Sp02 Measurement,” Agilent Technologies, printed from http://www.healthcare.agilent.com/cms—update/product—information/sp02.html on Feb. 15, 2001, pp. 1-2. |
A. Cohen et al., “A Light Emitting Diode Skin Reflectance Oximeter,” Medical & Biological Engineering, Journal of the International Federation for Medical and Biological Engineering, vol. 10, pp. 385-391, cover page, acknowledgement page, Total pp. 12, 1972. |
Braun, S., et al., “Mechanical Signature Analysis—Theory and Applications,”pp. 142-145, 202-203 (1986). |
Brown, David, P., “Evaluation of Pulse Oximeters using Theoretical Models and Experimental Studies” Masters Thesis, University of Washington, 1987. |
Bruce H. McCormick et al., “Computer Eye Looks at Human Eye”, p. 687-697. |
C. Zamarron et al., “Oximetry spectral analysis in the diagnosis of obstructive sleep apnoea,” The Biochemical Society and the Medical Research Society, 1999, pp. 467-473. |
Chen, J., et al., “Adaptive System for Processing of Electrogastric Signals,” Images of the Twenty-First Centry, vol. 11, pp. 698-699, Seattle, WA, Nov. 9-12, 1989. |
Cohen, Arnon Ph.D., “vol. I: Time and Frequency Domains Analysis”, Biomedical Signal Processing, CRC Press, Inc., pp. 152-159. |
Complaint for Patent Infringement, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-000080(JJF)), dated Feb. 3, 2009. |
Copending U.S. Appl. No. 10/005,631, filed Dec. 4, 2001, and pending claims. |
Copending U.S. Appl. No. 09/195,791, filed on Nov. 17, 1998, and pending claims. |
Deborah S. Bland, RN, “Pulse Oximetry, Monitoring Arterial Hemoglobin Oxygen Saturation,” Aorn Journal, Apr. 1987, vol. 45, No. 4, pp. 964-967, cover page, gen info page, Total pp. 5. |
Defendant/Counterclaim-Plaintiff Philips Electronics North America Corporation Answer to Masimo's Counterclaims, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated Aug. 3, 2009, pp. 1-23. |
Defendants' Answer and Philips Electronics North America Corporation's Counterclaims to Masimo's First Amended Complaint, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated Jun. 5, 2009. |
Defendants' Answer and Philips Electronics North America Corporation's Amended Counterclaims to Masimo's First Amended Complaint, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated Apr. 21, 2010. |
Doblar, D.O. et al., “Dynamic Characteristics of Cerebral Blood Flow Response to Sinusoidal Hypoxia,” American Physiological Society, 1979, pp. 721-729. |
E. M. Sevick et al., “Quantitation of Time- and Frequency-Resolved Optical Spectra for the Determination of Tissue Oxygenation,” Analytical Biochemistry 195, pp. 330-351. |
F.F. Jobsis, “Noninvasive, Infrared Monitoring of Cerebral and Myocardial Oxygen Sufficiency and Circulatory Parameters,” Science, vol. 198, No. 4323, Dec. 23, 1977, pp. 1264-1267, table of contents pp. (2), Total pp. 6. |
Farid U. Dowla et al., “Neural Networks and Wavelet Analysis in the Computer Interpretation of Pulse Oximetry Data,” pp. 527-536, 1996, Oct. 29, 1990. |
Fast-SpO2 Pulse oximetry, printed from http://www.medical.philips.com/main/products/patient—monitoring/products/fast—spo2/in . . . on Oct. 30, 2006, pp. 1-3. |
Felix W. Leung, MD. et al., “Gastroduodenal mucosal hemodynamics by endoscopic reflectance spectrophotometry,” Gastrointestinal Endoscopy, 1987, vol. 33, No. 4, Aug. 1987, pp. 284-288, table of contents page, Total pp. 6. |
Ferrara, E.R., “Fetal Electrocardiogram Enhancement by Time-Sequenced Adaptive Filtering,” IEEE Transactions on Biomedical Engineering, vol. BME-29, No. 6, Jun. 1982. |
Findings of Fact and Conclusion of Law Regarding Masimo's Motion for Preliminary Injunction, Masimo v. Mallinckrodt Inc., et al., U.S. District Court, Central District of California (Southern Division), Civil Action No. SA-CV-99/1245 AHS (Anx), filed Nov. 2, 2000 (Redacted). |
First Amended Complaint for Patent Infringement, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Boblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated May 12, 2009. |
Glover, Jr., J.R., “Adaptive Noise Canceling of Sinussoidal Interferences,” A Dissertation Submitted to the Department of Electrical Engineering and the Committee on Graduate Studies of Stanford University in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy, pp. iii-82 (1975). |
H.S. Lim et al., “The Study of Signal Processing Method in Frequency Domain for Measuring Oxygen Saturation in Biological Tissue,” pp. 527-530, 2000. |
Hanson, P.G. et al., “Influence of Breathing Pattern on Oxygen Exchange During Hypoxia and Exercise,” Journal of Applied Physiology, Jun. 1975, vol. 38, No. 6. |
Harris, et al., “Digital Signal Processing with Efficient Polyphase Recursive All-Pass Filter,” International Conference, Florence, Italy, (Sep. 26, 1991). |
Haykin, Simon, Adaptive Filter Theory, Prentice Hall, Englewood Cliffs, NJ, 1985. |
Haykin, Simon, Adaptive Filter Theory, Prentice Hall, Englewood Cliffs, NJ, 1985, Chapter 9, “Recursive Least-Squares Lattice Filters,” pp. 451-493, 1985. |
Hendry, S.D., “Computation of Harmonic Comb Filter Weights,” IEEE Transactions on Signal Processing, vol. 41, No. 4, Apr. 1993. |
Hiramoto, J. et al., “Tissue Spectrum Analyzer for Medical Use,” Review of Laser Engineering, 1985, vol. 13, No. 2, pp. 165-170. |
J.C. Dorlas et al., “Pulse Oximetry—principles and first experiences during anesthesia,” Acta Anaesthesiologica Belgica, 1987, 38, No. 2. pp. 133-138,Cover page, table of contents pp. 1-4, Total pp. 10. |
J.M. Kim, et al., “Signal Processing Using Fourier & Wavelet Transform for Pulse Oximery,” pp. 310-311. |
Jingzheng, O., et al., “Digital Processing of High-Resolution Electrocardiograms-Detection of His Purkinje Activity From the Body Surface,” Biomedizinische Technik, vol. 33, No. 10, pp. 224-230, Berlin, Germany, Oct. 1, 1988. |
Joachim S. Gravestein, MD., “Sampling Intervals for Clinical Monitoring of Variables During Anesthesia,” Journal of Clinical Monitoring, vol. 5. No. 1. Jan. 1989, pp. 17-21, cover page, Total pp. 6. |
Joseph M. Schmitt et al., “An Integrated Circuit-Based Optical Sensor for In Vivo Measurement of Blood Oxygenation,” IEEE Transactions on Biomedical Engineering, vol. BME-33, No. 2, Feb. 1986, pp. 98-107. |
Kamata, T. et al., “In Vivo Analysis of Hepatic Hemodynamics by Reflectance Spectrophotometry,” Kan, Tan, Sui, 1986, vol. 12, No. 5, pp. 725-730. |
Karen Riedel, RN, “Pulse oximetry: A new thechnology to assess patient oxygen needs in the neonatal intensive care unit”, The Journal of Perinatal and Neonatal Nursing, Jul. 1987, pp. 49-57, cover pages, Total pp. 11. |
Kent K. Gillingham et al., “Transfer Functions for Arterial Oxygen Saturation During +Gz Stress,” Aviation Space and Environmental Medicine, vol. 46, No. 11. Nov. 1975, pp. 1329-1335. |
Klimasauskas, Casey, “Neural Nets and Noise Filtering” Article, Dr. Dobb's Journal, Jan. 1989, pp. 32-34, 36-38, 42, 47, 49, 96, 98, 100. |
Leon Bennett, Mae, “Spectrum Analysis of Large Toe Plethysmographic Waveshape,” Arch Phys Med. Rehabil. vol. 66, May 1985, pp. 280-285. |
Li, G., “A Stable and Efficient Adaptive Notch Filter for Direct Frequency Estimation,” IEEE Transactions on Signal Processing, vol. 45, No. 8, Aug. 1987. |
Lisbet Jansson et al., “Noise Reduction of ECG by Averaging—An Experimental Study of the Procedure and a Validated Method,” pp. 781-787, 1975. |
Lloyd A. Marks, “Digital Enhancement of the Peripheral Admittance Plethysmogram,” IEEE Transactions on Biomedical Engineering, vol. BME-34, No. 3, Mar. 1987, p. 192-198. |
M. Brunner et al., “Some Aspects of Signal Analysis Applied to Intracapillary Hemoglobin Spectra,” pp. 803-810. |
M. Brunner, “Measurements and Processing of Intracapillary Hemoglobin Spectra by Using a Micro-Lightguide Spectrophotometer in Connection with A Microcomputer,” pp. 909-916. |
M.B. Taylor et al., “The current status of pulse oximetry—Clinical value of continuous noninvasive oxygen saturation monitoring,” Anesthesia, 1986, vol. 41, pp. 943-949, Contents page, Total pp. 8. |
Makino, M. et al., “Spectrophotometric Detennination of Oxygen Saturation in Blood,” The Japanese Journal of Clinical Pathology, 1986, vol. 16, No. 8, pp. 647-650. |
Mallinckrodt inc. v. Masimo Corp., 2004 U.S. Dist. Lexis 28518 (C.D. Cal. Jul. 12, 2004). |
Mallinckrodt, Inc. v. Masimo Corp., 147 Fed. Appx. 158, 2005 WL 2139867 (Fed. Cir. 2005). |
Masimo's Answer to Philips' Amended Counterclaims, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF) dated May 10, 2010. |
Masimo's Answer to Philips' Counterclaims, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated Jul. 9, 2009. |
Matthew James Hayes et al., “A New Method for Pulse Oximetry Possessing Inherent Insensitivity to Artifact,” IEEE Transactions on Biomedical Engineering, vol. 48, No. 4., Apr. 2001, pp. 452-461. |
Melnikof, Steve, “Neural Networks for Signal Processing: A Case Study” Article, Dr. Dobb's Journal, Jan. 1989, pp. 36-37. |
Memorandum of Decision and Order Re: Claim Construction; Motion to Strike Masimo's Declarations dated Feb. 27, 2003. |
Michael W. Wukitsch et al., “Knowing Your Monitoring Equipment,” Journal of Clinical Monitoring, vol. 4. No. 4, Oct. 1988, pp. 290-301, cover page, Total pp. 13. |
Min, B.G., et al., “Frequency-Domain Analysis of Oxygen Stores During Hypoxia in the Goat,” Annals of Biomedical Engineering, vol. 6 No. 4. |
Mook, G.A., et al., “Spectrophotometric determination of oxygen saturation of blood independent of the presence of indocyanin green”, Cardiovascular Research, vol. 13, 1979, pp. 233-237. |
Mook, G.A., et al., “Wavelength dependency of spectrophotometric determination of blood oxygen saturation”, Clinical Chemistry Acta, vol. 26, 1969, pp. 170-173. |
Nehorai, A., “A Minimal Parameter Adaptive Notch Filter With Constrained Poles and Zeros,” IEE Transactions on Acoustics, Speech, and Signal Processing, vol. ASSP-33, No. 4, Aug. 1985. |
Nehorai, A., “Adaptive Comb Filtering for Harmonic Signal Enhancement,” IEEE Transactions on Acoustics, Speech, and Signal Processing, vol. ASSP-34, No. 5, Oct. 1986. |
Nellcor's and Mallinckrodt's Amended and Supplemental Answer and Counterclaims to Masimo Corporation's First Amended Complaint in Case No. CV-01-7293-MRP (AJWx). |
Nellcor's and Mallinckrodt's Amended Complaint for Patent Infringement. |
Nellcor's and Mallinckrodt's First Amended and Supplemental Reply and Counterclaims to Counterclaims of Masimo Corporation. |
Nellcor's and Mallinckrodt's Opening Claim Construction Brief on the Patents-In-Suit dated Sep. 16, 2002. |
Nellcor's and Mallinckrodt's Reply Claim Construction Brief on the Patents-In-Suit dated Oct. 18, 2002. |
Nellcor's Third Amended Complaint for Patent Infringement. |
Neuman, Michael R., “Pulse Oximetry: Physical Principles, Technical Realization and Present Limitations”, Continuous Transcutaneous Monitoring, Plenum Press, New York, 1987, pp. 135-144. |
Non-Confidential Brief of Defendants-Cross Appellants Mallinckrodt Inc. and Nellcor Puritan Bennett, Inc. dated Jan. 22, 2001. |
Non-Confidential Brief of Plaintiff-Appellant Masimo Corporation dated Dec. 8, 2000. |
Non-Confidential Reply Brief of Defendants-Cross Appellants Mallinckrodt Inc. and Nellcor Puritan Bennett, Inc. dated Feb. 22, 2001. |
Non-Confidential Reply Brief of Plaintiff-Appellant Masimo Corporation dated Feb. 6, 2001. |
Pau, L.F., “Acoustic and Vibration Monitoring,” Failure Diagnosis and Performance Monitoring, Chapter 13, pp. 295-299. |
Philips Electronics North America Corporation's Answer to Masimo's Amended Counterclaims, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated May 27, 2010. |
Philips North America Corporation and Philips Medizin Systeme Böblingen GmbH's Seventh Supplemental Objections and Responses to Masimo Corporation's First Set of Interrogatories (Nos. 1- 8), Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 09-00080(JJF)) dated Jun. 30, 2010 (Redacted). |
R. Pahl et al., “Reflectance Spectrometry in Whole Blood Using a CCD Array Camera Part 1: Haematocrit Independent Measurement of Oxygen Saturation with the Aid of a New Evaluating Method,” Biomed. Technik 33 (1988), pp. 240-246. |
Rabiner, L.R. et al., “The Chirp z-Transform Algorithm and Its Application,” Bell System Technical Journal, May-Jun. 1969, vol. 48, No. 5, pp. 1249-1292. |
Rabiner, Lawrence R. et al., “Theory and Approximation of Infinite Impulse Response Digital Filters”, Prentice Hall Inc., Englewood Cliffs, NJ, 1975, p. 260. |
Radda, G.K. et al, “Recent Studies on Cellular Metabolism by Nuclear Magnetic Resonance,” Annual Review of Physiology, 1979, vol. 41, pp. 749-769. |
Razieh Semnani et al., “Quantitative evaluation of arterial pulsatile flow and pressure, applying impedance plethysmography to a human arterial model incorporating anatomical branching and scale,” Computer Methods and Programs in Biomedicine 25 (1987), pp. 13-20. |
Richard G. Aseltine, Jr., et al., “New Motion Resistant Sp02—Algorithm by Frequency Domain Signal Analysis,” Agilent Technologies, pp. 1-10, undated. |
S. Kojima et al., “Tissue Oxygen Saturation by Reflectance Spectrum Oxymetry in Myocardial Ischemia”, Circulation, vol. 72, No. 4, Part II, Total pp. 3 Oct. 1985. |
Sakata, M. et al., “Rapid Determination of Carboxyhemoglobin by Absorbance Difference Between Double Wavelength,” The Journal of Toxicological Science, 1980, vol. 5, pp. 113-121. |
Scharf J.E. and Rusch T.L., “Optimization of Portable Pulse Oximetry through Fourier Analysis”, Proceedings of the Twelfth Southern Biomedical Engineering Conference, p. 233-235, Apr. 1993. |
Scharf J.E., Athan S. Cain D, “Pulse Oximetry through Spectral Analysis”, Proceedings of the Twelfth Southern Biomedical Engineering Conference, p. 227-232, Apr. 1993. |
Setsuo Takatani et al., “A Miniature Hybrid Reflection Type Optical Sensor for Measurement of Hemoglobin Content and Oxygen Saturation of Whole Blood,” IEEE Transactions on Biomedical Engineering, vol. 35. No. 3, Mar. 1988, pp. 187-198. |
Severinghaus, John W. M.D., “Pulse Oximetry Uses and Limitations” , ASA Convention. |
Takashi Hanioka, “Evaluation of Hemoglobin Concentration and Oxygen Saturation in Inflamed Gingiva by Tissue Reflectance Spectrophotometry,” J. Osaka Univ. Dent. Soc., vol. 33, pp. 437-455, 1988. |
Tremper, Kevin K. et al., “Pulse Oximetry: Technical Aspects of Machine Design” by Jonas A. Pologe, Advances in Oxygen Monitoring, Little, Brown and Company, 1987, pp. 137-153. |
United States Courts of Appeals for the Federal Circuit—Opinion, Case No. 01-1028, -1084, Masimo v. Mallinckrodt, Inc. and Nellcor Puritan Bennett, Inc., Decided: Aug. 8, 2001. |
United States Courts of Appeals for the Federal Circuit: Mallinckrodt, Inc. v. Masimo Corp., 147F.App'x 158 (Fed. Cir 2005), (unpublished). |
United States Courts of Appeals for the Federal Circuit: Mallinckrodt, Inc. v. Masimo Corp., 402 F.3d 1364 (Fed. Cir. 2005). |
United States Courts of Appeals for the Federal Circuit: Masimo Corp. v. Mallinckrodt, Inc., 18 F App'x 852 (Fed. Cir. 2001). |
United States District Court—Civil Minutes, Case No. SA CV 99/1245 AHS (ANX), Masimo v. Mallinckrodt and Nellcor Puritan Bennett, Dated Oct. 4, 2000. |
V. Ya. Volkov et al., “Enhancing the Reliability and Accuracy of Pulse Oximetry with a Built-In Expert System,” 1993 Plenum Publishing Corporation, pp. 133-138. |
Varanini, M., et al. “A Two Channel Adaptive Filtering Approach for Recognition of the QRS Morphology,”pp. 141-144, Proceedings of the Computers in Cardiology Meeting, Venice, Institute of Electrical and Electronics Engineers, Sep. 23-26, 1991. |
Widrow, B., “Adaptive Noise Canceling: Principles and Applications,”Proceedings of IEEE, vol. 63, No. 12, Dec. 1975. |
Widrow, Bernard, Adaptive Signal Processing, Prentice Hall, Englewood Cliffs, NJ, 1985. |
Widrow, Bernard, Adaptive Signal Processing, Prentice Hall, Englewood Cliffs, NJ, Chapter 1 “Adaptive Systems”, pp. 3-13, 1985. |
Widrow, Bernard, et al., Chapter 12: “The Adaptive Interference Canceling” Adaptive Signal Processing, Prentice-Hall, Inc., pp. 302-367, 1985. |
Widrow, Bernard, et al., Chapter 2: “The Adaptive Linear Combiner”, Adaptive Signal Processing, Prentice-Hall, Inc., pp. 15-26, 1985. |
Wukitsch, M.W., et al., “Pulse Oximetry: Analysis Theory, Technology, and Practice,” Journal of Clinical Monitoring, vol. 4, No. 4, pp. 290-301 (Oct. 1988). |
Y. Shimada et al., “Effects of multiple scattering and peripheral circulation on arterial oxygen saturation measured with a pulse-type oximeter,” Medical & Biological Engineering & Computing, Sep. 1984, pp. 475-478. |
Yelderman, M., et al., “Ecg Enhancement by Adaptive Cancellation of Electrosurgical Interference,” pp. 1-21. |
Yelderman, M., et al., “Sodium Nitroprusside Infusion by Adaptive Control,” Adaptive Control by Inverse Modeling, Conference Record: 12th Asilosor Conference 90 (1978). |
Yu, C., et al., “Improvement in Arterial Oxygen Control Using Multiple Model Adaptive Control Procedures,” pp. 878-883. |
Answer and Counterclaims of Shenzhen Mindray Bio-Medical Electronics Co., Ltd., D.I. 53, dated May 31, 2013, Masimo Corp. v. Mindray DS USA, Inc. and Shenzhen Mindray Bio-Medical Elecs. Co., Ltd. (C.D. Cal. filed Dec. 21, 2012). |
Appendixes for Expert Report of Dr. Robert Stone Regarding the invalidity of Masimo's Patents-in-Suit (U.S. Patent No. 5,632,272, U.S. Patent No. 6,263,222, U.S. Patent No. 7,215,984, and U.S. Patent No. 6,699,194, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 7, 2012. |
Blitt, Casey D., Monitoring in Anesthesia and Critical Care Medicine, (2d ed. 1990). |
Boualem Boashash, Estimating and Interpreting the Instantaneous Frequency of a Signal-Part I: Fundamentals, Proceedings of the IEEE, vol. 80, No. 4 (Apr. 1992). |
Boualem Boashash, Note on the Use of the Wigner Distribution for Time-Frequency Signal Analysis, IEEE Transactions on Acoustics, Speech, and Signal Processing, vol. 36, No. 9 (Sep. 1988). |
Business Wire, “Mallinckrodt Announces the Nellcor N-395 Pulse Oximeter With Oxismart XL and SatSeconds,” Oct. 7, 1999. |
Complaint, D.I. 1, dated Dec. 21, 2012, Masimo Corp. v. Mindray DS USA, Inc. and Shenzhen Mindray Bio-Medical Elecs. Co., Ltd. (C.D. Cal. filed Dec. 21, 2012). |
Declaration of Clark R. Baker, dated Aug. 15, 2000, Trial Exhibit JTX-1133, Masimo Corp. v. Mallinckrodt, Inc., SA-CV-99/1245-AHS-ANX (C.D. Cal.). |
Declaration of Gail Baura, Ph.D. In Support of Masimo's Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 7,215,984, Doc. 561, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Gail Baura, Ph.D. In Support of Masimo's Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 5,632,272, Doc. 554, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Gail Baura, Ph.D. In Support of Masimo's Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,263,222, Doc. 551, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Gail Baura, Ph.D. In Support of Masimo's Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,699,194, Doc. 508, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 21, 2012. |
Declaration of Mohammed K. Diab in Support of Masimo's Oppositions to Defendants' Motions for Summary Judgment of Invalidity and Noninfringement of U.S. Patent Nos. 5,632,272 and 7,215,984, Doc. 563, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012 (Redacted). |
Declaration of Perry D. Oldham in Support of Masimo Opposition to Defendant's Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 7,215,984, vol. 1, Doc. 556, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Perry D. Oldham in Support of Masimo Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 5,632,272, Doc. 553, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Perry D. Oldham in Support of Masimo Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,699,194, Doc. 548, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Perry D. Oldham in Support of Masimo's Opposition to Defendant's Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 7,215,984, vol. 2, Doc. 558, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Declaration of Perry D. Oldham in Support of Masimo's Opposition to Defendant's Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,263,222, Doc. 550, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28. 2012 (Redacted). |
Declaration of Thomas J. Yorkey, dated Aug. 20, 2000, Trial Exhibit JTX-1134, Masimo Corp. v. Mallinckrodt, Inc., SA-Cv-99-1245-AHS-ANX (C.D. Cal.). |
Defendants' Answer and Philips Electronics North America Corp.'s Counterclaims to Masimo's First Amended Complaint, Doc. 11, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:11-cv-00742 (LPS/MPT) dated Nov. 7, 2011. |
Defendants' Answer and Philips Electronics North America Corp.'s Counterclaims to Masimo's Second Amended Complaint, Doc. 43, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:11-cv-00742 (LPS/MPT) dated May 11, 2012. |
Defendants' Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 5,632,272, Doc. 402, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 14, 2012. |
Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,263,222, Doc. 410, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 14, 2012. |
Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,699,194, Doc. 406, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 14, 2012. |
Defendants' Objections to Magistrate Judge Thynge's Apr. 2, 2013 Report and Recommendation Regarding Philips' Motions for Summary Judgment, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 26, 2013. (Redacted). |
Defendants' Objections to Magistrate Judge Thynge's Report and Recommendation Regarding Claim Construction, Doc. 218, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Mar. 7, 2011. |
Defendants' Response to Masimo Corporation's Objections to Magistrate Judge Thynge's Apr. 2, 2013 Report and Recommendation Regarding Summary Judgment, Doc. 696, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 13,2013. (Redacted). |
Deposition of Ibrahim Elfadel taken Nov. 23, 2010, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Deposition of Joe Kiani taken Apr. 6, 2011, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv00080 (LPS/MPT). (Redacted). |
Deposition of Joe Kiani taken Apr. 7, 2011, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv00080 (LPS/MPT). (Redacted). |
Deposition of Joe Kiani taken Sep. 27, 2011, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Deposition of Mohammed Diab taken Feb. 3, 2011, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Deposition of Rex McCarthy taken Nov. 3, 2010, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Deposition of Robert Smith taken Dec. 7, 2010, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Deposition of Walter Weber taken Dec. 8, 2010, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Deposition of Walter Weber taken Dec. 9, 2010, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT). (Redacted). |
Edward Bedrosian, The Analytic Signal Representation of Modulating Waveforms (1962). |
Excerpts from the Transcript of Record, testimony of Dr. Robert Stone, pp. 1696-1699, 1780-1795, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Excerpts from the Transcript of Record, testimony of Dr. Robert Stone, pp. 1796-1799, 1812-1884, Mallickrodt, Inc. v Masimo Corp., No. cv-00/6506-MRP (C.D. Cal.). |
Exhibits A-G for Masimo Corporation's Objections to the Report and Recommendation Regarding Summary Judgment, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 26, 2013. (Redacted). |
Expert Report of Dr. Robert Stone Regarding the invalidity of Masimo's Patents-in-Suit (U.S. Patent No. 5,632,272, U.S. Patent No. 6,263,222, U.S. Patent No. 7,215,984, and U.S. Patent No. 6,699,194, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 7, 2012. |
Hanzo , “A Portable Multimedia Communicator Scheme”, Multimedia Technologies and Future Applications: Proceedings of the IEEE International Symposium (1994). |
Maciej Niedzwiecki “Smoothing of Discontinuous Signals: The Competitive Approach,” IEEE Transactions on Signal Processing, vol. 43, No. 1, Jan. 1995, pp. 1-13. |
Masimo Corp v. Mallinckrodt, Inc., 18 F. App'x 852 (Fed. Cir. Aug. 8, 2001). |
Masimo Corporation's Answering Brief in Opposition to Defendant's Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent. No. 7,215,984, Doc. 555, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Masimo Corporation's Answering Brief in Opposition to Defendant's Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 5,632,272, Doc. 552, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012. (Redacted). |
Masimo Corporation's Answering Brief in Opposition to Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,263,222, Doc. 549, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Sep. 28, 2012 (Redacted). |
Masimo Corporation's Objections to the Report and Recommendation Regarding Philips' Motions for Summary Judgment, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 26, 2013. (Redated). |
Masimo Corporation's Objections to the Report and Recommendation Regarding Claim Construction, Doc. 219, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Mar. 8, 2011. |
Masimo Corporation's Response to Defendants' Objections to the Report and Recommendation Regarding Claim Construction, Doc. 232, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv00080 (LPS/MPT) dated Mar. 24, 2011. |
Masimo Corporation's Response to Philips' Objections to the Apr. 2, 2013 Report and Recommendation Regarding Summary Judgment, Doc. 697, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 13, 2013. (Redacted). |
Masimo's Answer to Philips' Counterclaims to Masimo's Second Amended Complaint, Doc. 358, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:11-cv-00742 (LPS/MPT) dated Jun. 4, 2012. |
Masimo's Answer to Philips' Counterclaims, Doc. 28, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:11-cv-00742 (LPS/MPT) dated Dec. 30, 2011. |
Memorandum Order Adopting Report and Recommendation Regarding Claim Construction, Doc. 319, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Jan. 17, 2011. |
Notice of Intent to Issue Ex Parte Reexamination Certificate issued in Reexamination Application No. 90/012,542 on Oct. 23, 2013. |
Opening Brief in Support of Defendants' Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 5,632,272, Doc. 444, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 21, 2012. (Redacted). |
Opening Brief in Support of Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,699,194, Doc. Doc 445, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 21, 2012. (Redacted). |
Order of District Court Regarding Defendant's Motion for Summary Judgment of Non-Infringement of '642 Patent, among others, dated Oct. 4, 2000, Masimo v. Mallicnkrodt Inc., cv-99-1245-AHS (C.D. Cal.). |
Philip Defendant's Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 7,215,984, Doc. 394, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 14, 2012. |
Philip's Opening Brief in Support of Defendant's Motion for Summary Judgment of Invalidity and Nonnigringement of U.S. Patent No. 7,215 Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 21, 2012. (Redacted). |
Philips' Opening Brief in Support of Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,263,222, Doc. 413, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Aug. 14, 2012. |
Philips' Response to Masimo Corporation's Objections to the Report and Recommendation Regarding Claim Construction, Doc. 230, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Mar. 24, 2011. |
Reply Brief in Support of Defendants' Motion for Summary Judgment of invalidity and Noninfringement of U.S. Patent. No. 7,216,984, Doc. 609, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Oct. 26, 2012. (Redacted). |
Reply Brief in Support of Defendants' Motion for Summary Judgment of Invalidity and Noninfringement of U.S. Patent No. 5,632,272, Doc. 614, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Oct. 26, 2012 (Redacted). |
Reply Brief in Support of Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,263,222, Doc. 613, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Oct. 26, 2012 (Redacted). |
Reply Brief in Support of Defendants' Motion for Summary Judgment of Invalidity of U.S. Patent No. 6,699,194, Doc. 610, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Oct. 26, 2012. (Redacted). |
Report and Recommendation Regarding Claim Construction, Doc. 210, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Feb. 18, 2011. |
Report and Recommendation Regarding Motions for Summary Judgment and Motions to Exclude, Doc. 662, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 2, 2013. |
Revised Expert Report of Dr. Robert Stone Regarding the invalidity of Masimo's Patents-in-Suit (U.S. Patent No. 5,632,272, U.S. Patent No. 6,263,222, U.S. Patent No. 7,215,984, and U.S. Patent No. 6,699,194, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 7, 2012. |
Rusch, “Master's Thesis,” Graduate School University of South Florida, Tampa, Florida (Dec. 1994). |
Second Amended Complaint for Patent Infringement, Doc. 42, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:11-cv-00742 (LPS/MPT) dated Apr. 25, 2012. |
Steven W. Smith, The Scientist and Engineer's Guide to Digital Signal Processing, § 8 (1st ed. 1997). |
Supplemental Expert Report of Dr. Robert Stone Regarding the invalidity of Masimo's Patents-in-Suit (U.S. Patent No. 5,632,272, U.S. Patent No. 6,263,222, U.S. Patent No. 7,215,984, and U.S. Patent No. 6,699,194, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Mar. 18, 2012. |
Trial Exhibit JTX-212, Patent No. 6,157,850, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-213, File History Patent No. 5,632,272, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-2643, Mallinckrodt 395 Overview, Mallickrodt, Inc. v Masimo Corp.,No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4500, Slide PCSat Development, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4869, Slide Robert T. Stone, Ph.D.—Educational History, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4870, Slide Robert T. Stone, Ph.D.—Work Experience, Mallickrodt, Inc. v Masimo Corp.,No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4890, Slide Comparison of '850 Patent Claim 1 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4891, Slide Comparison of '850 Patent Claim 1 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4892, Slide Comparison of '850 Patent Claim 1 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4893, Slide Comparison of '850 Patent Claim 1 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4895, Slide Comparison of '850 Patent Claim 11 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4897, Slide Comparison of '850 Patent Claim 12 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4900, Slide Comparison of '850 Patent Claim 12 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4902, Slide Comparison of '850 Patent Claim 22 to the N-200, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4903, Slide Nellcor Began Using Alternative Calculations in the 1980s, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4904, Slide Fetal Oximeter Features, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4905, Slide Fetal Oximeter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4906, Slide Comparison of '850 Patent Claim 1 to the Fetal Oximeter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4907, Slide Comparison of '850 Patent Claim 1 to the Fetal Oximeter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4908, Slide Comparison of '850 Patent Claim 1 to the Fetal Oximter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4909, Slide Comparison of '850 Patent Claim 1 to the Fetal Oximeter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4910, Slide Comparison of '850 Patent Claim 10 to the Fetal Oximeter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4911, Slide Comparison of '850 Patent Claim 11 to the Fetal Oximeter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4914, Slide PCSat Features, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4917, Slide Comparison of '850 Patent Claim 1 to the PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4918, Slide Comparison of '850 Patent Claim 1 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4919, Slide Comparison of '850 Patent Claim 1 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4920, Slide Comparison of 850 Patent Claim 1 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4921, Slide Comparison of '850 Patent Claim to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4922, Slide Comparison of '850 Patent Claim 10 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4923, Slide Comparison of '850 Patent Claim 11 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4924, Slide Comparison of '850 Patent Claim 12 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4925, Slide Comparison of '850 Patent Claim 15 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4926, Slide Comparison of '850 Patent Claim 22 to PCSat, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4933, Slide Uemura Patent, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4936, Slide Comparion of '850 Patent Claim 1 to Uemura, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4937, Slide Comparison of '850 Patent Claim 1 to Uemura, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4939, Slide Comparison of '850 Patent Claim 1 to Uemura, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4942, Slide Comparison of '850 Patent Claim 1 to Uemura, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-4947, Slide '850 Patent Opinions on Description and Enablement of a Kalman Filter, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.). |
Trial Exhibit JTX-541, Patent No. 4,928,692 , Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.) Issued Mar. 29, 1990. |
Trial Exhibit JTX-547, Patent No. 5,054,495, Mallickrodt, Inc. v Masimo Corp., No. cv-00-6506-MRP (C.D. Cal.) Issued Oct. 8, 1991. |
U.S. Appl. No. 90/012,551, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 6,970,792, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,553, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,024,233, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,403, filed Jul. 23, 2012, requesting ex parte reexamination of Patent No. 6,263,222, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,463, filed Sep. 5, 2012, requesting ex parte reexamination of Patent No. 7,215,984, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,532, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,499,835, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,534, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,962,188, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,538, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,377,899, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,541, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,899,507, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,542, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 8,180,420, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,543, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 6,850,787, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,546, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,438,683, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,548, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,880,606, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,557, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 8,150,487, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,559, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 8,190,223, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,561, filed Sep. 14, 2012, requesting ex parte reexamination of Patent No. 8,019,400, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,562, filed Sep. 14, 2012 requesting ex parte reexamination of Patent No. 6,463,311, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,566, filed Sep. 14, 2012, requesting ex parte reexamination of Patent No. 7,530,955, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,567, filed Sep. 14, 2012, requesting ex parte reexamination of Patent No. 6,684,090, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,568, filed Sep. 14, 2012, requesting ex parte reexamination of Patent No. 8,128,572, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012,699, filed Oct. 4, 2012, requesting ex parte reexamination of Patent No. 6,002,952, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 90/012.555, filed Sep. 13, 2012, requesting ex parte reexamination of Patent No. 7,440,787, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
U.S. Appl. No. 95/002,183, filed Sep. 12, 2012, requesting inter partes reexamination of Patent No. 7,530,955, including accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.913 and 35 U.S.C. § 311. |
U.S. Appl. No. 90/012,409, filed Aug. 17, 2012, requesting ex parte reexamination of Patent No. 6,699,194, includin442 g accompanying Reexam Request, claim charts, and other documentation filed under 37 C.F.R. § 1.510 and 35 U.S.C. § 302. |
V. Ya. Volkov, “Principles and Algorithms for Determining Blood Oxygenation Level by Pulse Oximetry,” Biomedical Engineering, vol. 27, No. 1 (Jan.-Feb. 1993) (translated from Russian). |
Public Version of Memorandum Opinion, Doc. 781, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 7, 2014. |
Opening Brief in Support of Masimo's Motion for Reconsideration of the Court's Order and Memorandum Opinion, Doc. 790, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 15, 2014. (Redacted). |
Defendants' Motion for Reargument Regarding the Order Overruling Philips' Objection that Claims 15, 16, 19, 20, 53, and 54 of U.S. Patent No. 7,215,984 Are Not Infringed, Doc. 792, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 25, 2014. (Redacted). |
Masimo Corporation's Opposition to Defendants' Motion for Reargument Regarding the Order Overruling Philips' Objection that Claims 15, 16, 19, 20, 53, and 54 of U.S. Patent No. 7,215,984 Are Not Infringed, Doc. 797, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 5, 2014. (Redacted). |
Defendants' Opposition to Masimo's Motion for Reconsideration of the Court's Order and Memorandum Opinion Regarding U.S. Patent No. 5,632,272, Doc. 798, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated May 5, 2014. (Redacted). |
Memorandum Order, Doc. 787, Masimo Corporation v. Philips Electronics North America Corporation and Philips Medizin Systeme Böblingen GmbH, (District of Delaware, Case No. 1:09-cv-00080 (LPS/MPT) dated Apr. 14, 2014. |
Number | Date | Country | |
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20120302894 A1 | Nov 2012 | US |
Number | Date | Country | |
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Parent | 08834194 | Apr 1997 | US |
Child | 09081539 | US |
Number | Date | Country | |
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Parent | 11842128 | Aug 2007 | US |
Child | 13471340 | US | |
Parent | 10791683 | Mar 2004 | US |
Child | 11842128 | US | |
Parent | 09547588 | Apr 2000 | US |
Child | 10791683 | US | |
Parent | 09081539 | May 1998 | US |
Child | 09547588 | US |