Simultaneous Stimulation and Recording in Scalable Multielectrode Arrays

Information

  • Research Project
  • 7482029
  • ApplicationId
    7482029
  • Core Project Number
    R43NS062477
  • Full Project Number
    1R43NS062477-01
  • Serial Number
    62477
  • FOA Number
    PA-06-23
  • Sub Project Id
  • Project Start Date
    7/15/2008 - 16 years ago
  • Project End Date
    11/30/2009 - 15 years ago
  • Program Officer Name
    SWAIN, AMY L
  • Budget Start Date
    7/15/2008 - 16 years ago
  • Budget End Date
    5/31/2009 - 15 years ago
  • Fiscal Year
    2008
  • Support Year
    1
  • Suffix
  • Award Notice Date
    7/7/2008 - 16 years ago
Organizations

Simultaneous Stimulation and Recording in Scalable Multielectrode Arrays

[unreadable] DESCRIPTION (provided by applicant): The proposed study utilizes novel electronics and microfabrication techniques to create scalable, in-vitro Multielectrode Array (MEA) technologies. This research will enable rapid advancements in the study of neural interactions and in the understanding and treatment of neural disorders. Phase I involves two significant developments for neural related research. Specifically, Aim 1 will develop scalable simultaneous stimulation and recording electronics to recover signals traditionally obscured by stimulation artifacts. The recovered data, combined with the ability to simultaneously interact with hundreds of electrodes, will provide new measures of single-cell and network-level neural activity. Aim 2 will produce scalable and inexpensive multi- well MEAs, which can be used in conjunction with the electronics developed in Aim 1 to yield a high- throughput neural toolset. Phase 2 will generate further increases in scale, while providing data manipula- tion algorithms along with real-time information extraction and control tools. This research uses novel electronic and fabrication technologies to create faster, lower-cost methods for neural research. Ultimately, this development will facilitate medical and scientific discoveries that will benefit the treatment of neural disorders such as Parkinson's and epilepsy. [unreadable] [unreadable] [unreadable]

IC Name
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
  • Activity
    R43
  • Administering IC
    NS
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    235601
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    389
  • Ed Inst. Type
  • Funding ICs
    NCRR:235600\NINDS:1\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    AXION BIOSYSTEMS, LLC
  • Organization Department
  • Organization DUNS
    802587035
  • Organization City
    DECATUR
  • Organization State
    GA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    300333010
  • Organization District
    UNITED STATES