Patent Grant
10874812
When a patient has difficulty breathing autonomously, it is a common practice to insert an external tubular tracheal ventilation tube, also known as Endo-Tracheal Tube (ETT). An ETT provides fresh air by a forced ventilation pump, and ejects air saturated with CO2. Thus, the breathing operation is performed instead of the patient and the needed oxygen is provided to the patient's organs.
During the forced ventilation process, excessive fluids and secretion are usually aggregated in the mouth and trachea of the patient. Some of the known ETTs include a “balloon”, i.e. an inflatable section, intended for blocking the fluids from entering further to the trachea and lungs.
According to an aspect of some embodiments of the present invention there is provided an add-on device for an Endo-Tracheal Tube (ETT), the add-on device including a lengthy body having a major arc-shaped cross section sized and shaped to tightly fit over an ETT, at least one longitudinal cavity passing along the lengthy body, comprising a distal suction cavity ending with a suction inlet at a distal end of the lengthy body, and a distal suction outlet channel extending from a proximal end of the lengthy body, the channel is a continuous extension of the distal suction cavity and configured to provide suction to the distal suction cavity.
In some embodiments of the present invention, the device includes a moisture sensor for detection of liquid at the distal end of the lengthy body and at least one sensor data channel going through at least one of the longitudinal cavities towards the proximal end of the device.
In some embodiments of the present invention, the device includes a mouth suction tube extending from an external surface of the lengthy body at a location corresponding to a patient's mouth, wherein the at least one longitudinal cavity further comprising a mouth suction cavity continuous to the mouth suction tube, and a mouth suction outlet channel extending from the proximal end of the lengthy body, the mouth suction outlet channel is a continuous extension of the mouth suction cavity and configured to provide suction to the mouth suction cavity.
In some embodiments of the present invention, the device includes a moisture sensor at the distal end of the mouth tube and at least one sensor data channel going through at least one of the longitudinal cavities towards the proximal end of the device.
In some embodiments of the present invention, the mouth suction tube is connected to the lengthy body by an axis perpendicular to the lengthy body at the connection point, the mouth suction tube tiltable about the axis to adjust the position of the mouth suction tube.
In some embodiments of the present invention, the device includes a liquid outlet at an external surface of the lengthy body at a location corresponding to a patient's mouth, wherein the at least one longitudinal cavity further comprising a liquid channel cavity continuous to the liquid outlet, and a liquid channel extending from the proximal end of the lengthy body, the liquid channel is a continuous extension of the liquid channel cavity and configured to provide liquid to the liquid outlet.
In some embodiments of the present invention, the liquid outlet is connected to the lengthy body by an axis perpendicular to the lengthy body at the connection point, the liquid outlet tiltable about the axis to adjust the position of the liquid outlet.
In some embodiments of the present invention, the device includes at a distal end of the lengthy body a recess formed in an internal wall of the lengthy body, configured to prevent clogging of the suction inlet.
In some embodiments of the present invention, the device includes an inlet at the distal end of the lengthy body and a CO2 sampling pipe continuous to the inlet going through at least one of the longitudinal cavities towards the proximal end of the device.
In some embodiments of the present invention, the device includes an outlet bundle of outlet channels including the distal suction outlet channel, the outlet bundle extending from the proximal end of the lengthy body.
In some embodiments of the present invention, the at least one longitudinal cavity pass in a thickness of the lengthy body.
According to an aspect of some embodiments of the present invention there is provided an add-on device for an Endo-Tracheal Tube (ETT), the add-on device including a liquid outlet at a location corresponding to a patient's mouth, a moisture sensor at a location corresponding to a patient's mouth, and at least one longitudinal cavity passing along the device and including a liquid channel cavity continuous to the liquid outlet, and a moisture sensor data channel, the liquid channel and data channel going through the at least one longitudinal cavities towards the proximal end of the device, wherein the liquid channel is adapted to guide liquid from a liquid source to the liquid outlet according to data transmitted through the moisture sensor data channel.
According to an aspect of some embodiments of the present invention there is provided a system including an add-on device for an Endo-Tracheal Tube (ETT), the add-on device including at least one longitudinal cavity passing along the device, comprising a distal suction cavity ending with a suction inlet at a distal end of the device, and a distal suction outlet channel extending from a proximal end of the device, the channel is a continuous extension of the distal suction cavity and configured to provide suction to the distal suction cavity, and a hub for operating the add-on device, the hub comprises a controller configured to control suction supply to the distal suction outlet channel according to moisture sensor data.
In some embodiments of the present invention, the device includes a lengthy body having a major arc-shaped cross-section.
In some embodiments of the present invention, the controller is configured to detect excessive wetness based on moisture sensor data, and when excessive wetness is detected, activate suction through the distal suction outlet channel.
In some embodiments of the present invention, the device includes a mouth suction tube extending from an external surface of the device at a location corresponding to a patient's mouth, wherein the at least one longitudinal cavity further comprising a mouth suction cavity continuous to the mouth suction tube, and a mouth suction outlet channel extending from the proximal end of the device, the mouth suction outlet channel is a continuous extension of the mouth suction cavity and configured to provide suction to the mouth suction cavity, wherein the controller is configured to switch a selection valve to select between the distal suction outlet channel and the mouth suction outlet channel, and switch a pinch valve to control suction supply to the selected suction outlet channel.
In some embodiments of the present invention, the device includes a liquid outlet at an external surface of the device at a location corresponding to a patient's mouth, wherein the at least one longitudinal cavity further comprising a liquid channel cavity continuous to the liquid outlet, and a liquid channel extending from the proximal end of the device, the liquid channel is a continuous extension of the liquid channel cavity and configured to provide liquid to the liquid outlet, wherein the controller is configured to activate a liquid source to provide liquid via the liquid channel.
In some embodiments of the present invention, the hub includes an air compressor, wherein the controller is configured to activate the air compressor to push liquid forcefully through the liquid channel.
In some embodiments of the present invention, the device includes an inlet at the distal end of the device and a CO2 sampling pipe continuous to the inlet going through at least one of the longitudinal cavities towards the proximal end of the device, and wherein the hub comprises a CO2 level sensor configured to receive a sample of air via the CO2 sampling pipe and to measure CO2 level in the sample.
In some embodiments of the present invention, the controller is configured to detect air leakage based on the measured CO2 level.
In some embodiments of the present invention, the controller is configured to control inflation of an inflatable section of the ETT based on sensor data.
According to an aspect of some embodiments of the present invention there is provided a method for controlling an add-on device for an Endo-Tracheal Tube (ETT), the method including, when the add-on device is installed on the ETT, sensing moisture at a distal end of the add-on device, and in case of detection of excessive wetness, provide suction to the distal end of the device through a cavity passing along the device, the suction is provided via a suction outlet channel extending from a proximal end of the device.
In yet another embodiments the said suction channels, the fluid channel as well as the moisture sensors are embedded in the ETT tube directly and connected to the hub by said cable.
In yet another embodiment a liquid absorbing media such as a sponge is replacing the balloon.
Unless otherwise defined, all technical and/or scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention pertains. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of embodiments of the invention, exemplary methods and/or materials are described below. In case of conflict, the patent specification, including definitions, will control. In addition, the materials, methods, and examples are illustrative only and are not intended to be necessarily limiting.
Some embodiments of the invention are herein described, by way of example only, with reference to the accompanying drawings. With specific reference now to the drawings in detail, it is stressed that the particulars shown are by way of example and for purposes of illustrative discussion of embodiments of the invention. In this regard, the description taken with the drawings makes apparent to those skilled in the art how embodiments of the invention may be practiced.
In the drawings:
The existing ETT ventilation tubes have some shortcomings. Secretion may be accumulated on the balloon and eventually may get into the lungs. Saliva and mucus may be accumulated in the mouth, and in some cases, for example when the patient doesn't eat and/or drink through the mouth, excessive dryness may be formed, which may cause infections.
In to some embodiments of the present invention a ventilation enhancement device is provided, which may be an add-on device for installation on the ETT with minimal or no interruption to the ventilation process, or may be integral with the ETT. The ventilation enhancement device according to some embodiments of the present invention enables removal of excessive fluids and secretion from the trachea and mouth during the ventilation by the ETT with no need to replace a currently installed ETT.
The provided add-on device may include a wrap with a c-shaped cross-section and/or a longitudinal slit, which may simply be snapped upon the ETT without requiring any additional installation steps.
The enhancement device may remove the fluids from the trachea by a suction inlet in the vicinity of the device's end. The fluids accumulated in the mouth may be removed by the enhancement device by a suction inlet on the wrap in a location corresponding to the patient's mouth. In order to avoid dryness in the mouth, fluid may be sprayed, periodically and/or when needed, out of an opening in the external surface of the wrap, in a location corresponding to the patient's mouth.
According to some embodiments of the present invention, suction may be provided to the enhancement device by a controller, according to signals received from dedicated sensors located at the vicinity of the suction inlets. Excessive fluids and secretion in the trachea and mouth may be detected, for example, by impedance measurements.
In some embodiments of the present invention, the enhancement device may detect an unwanted gap between the trachea wall and the balloon of the ETT. Such gap may cause leakage of secretion into the lungs. The detection of an unwanted gap is done by detection of air leaking from the gap, by detection of CO2 levels in the vicinity of the balloon. Detector signals may be provided to a controller, which may control the suction accordingly.
Before explaining at least one embodiment of the invention in detail, it is to be understood that the invention is not necessarily limited in its application to the details of construction and the arrangement of the components and/or methods set forth in the following description and/or illustrated in the drawings and/or the Examples. The invention is capable of other embodiments or of being practiced or carried out in various ways.
The present invention may be a system, a method, and/or a computer program product. The computer program product may include a computer readable storage medium (or media) having computer readable program instructions thereon for causing a processor to carry out aspects of the present invention.
The computer readable storage medium can be a tangible device that can retain and store instructions for use by an instruction execution device. The computer readable storage medium may be, for example, but is not limited to, an electronic storage device, a magnetic storage device, an optical storage device, an electromagnetic storage device, a semiconductor storage device, or any suitable combination of the foregoing. A non-exhaustive list of more specific examples of the computer readable storage medium includes the following: a portable computer diskette, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or Flash memory), a static random access memory (SRAM), a portable compact disc read-only memory (CD-ROM), a digital versatile disk (DVD), a memory stick, a floppy disk, a mechanically encoded device such as punch-cards or raised structures in a groove having instructions recorded thereon, and any suitable combination of the foregoing. A computer readable storage medium, as used herein, is not to be construed as being transitory signals per se, such as radio waves or other freely propagating electromagnetic waves, electromagnetic waves propagating through a waveguide or other transmission media (e.g., light pulses passing through a fiber-optic cable), or electrical signals transmitted through a wire.
Computer readable program instructions described herein can be downloaded to respective computing/processing devices from a computer readable storage medium or to an external computer or external storage device via a network, for example, the Internet, a local area network, a wide area network and/or a wireless network. The network may comprise copper transmission cables, optical transmission fibers, wireless transmission, routers, firewalls, switches, gateway computers and/or edge servers. A network adapter card or network interface in each computing/processing device receives computer readable program instructions from the network and forwards the computer readable program instructions for storage in a computer readable storage medium within the respective computing/processing device.
Computer readable program instructions for carrying out operations of the present invention may be assembler instructions, instruction-set-architecture (ISA) instructions, machine instructions, machine dependent instructions, microcode, firmware instructions, state-setting data, or either source code or object code written in any combination of one or more programming languages, including an object oriented programming language such as Smalltalk, C++ or the like, and conventional procedural programming languages, such as the “C” programming language or similar programming languages. The computer readable program instructions may execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer or entirely on the remote computer or server. In the latter scenario, the remote computer may be connected to the user's computer through any type of network, including a local area network (LAN) or a wide area network (WAN), or the connection may be made to an external computer (for example, through the Internet using an Internet Service Provider). In some embodiments, electronic circuitry including, for example, programmable logic circuitry, field-programmable gate arrays (FPGA), or programmable logic arrays (PLA) may execute the computer readable program instructions by utilizing state information of the computer readable program instructions to personalize the electronic circuitry, in order to perform aspects of the present invention.
Aspects of the present invention are described herein with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It will be understood that each block of the flowchart illustrations and/or block diagrams, and combinations of blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer readable program instructions.
These computer readable program instructions may be provided to a processor of a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions/acts specified in the flowchart and/or block diagram block or blocks. These computer readable program instructions may also be stored in a computer readable storage medium that can direct a computer, a programmable data processing apparatus, and/or other devices to function in a particular manner, such that the computer readable storage medium having instructions stored therein comprises an article of manufacture including instructions which implement aspects of the function/act specified in the flowchart and/or block diagram block or blocks.
The computer readable program instructions may also be loaded onto a computer, other programmable data processing apparatus, or other device to cause a series of operational steps to be performed on the computer, other programmable apparatus or other device to produce a computer implemented process, such that the instructions which execute on the computer, other programmable apparatus, or other device implement the functions/acts specified in the flowchart and/or block diagram block or blocks.
The flowchart and block diagrams in the Figures illustrate the architecture, functionality, and operation of possible implementations of systems, methods, and computer program products according to various embodiments of the present invention. In this regard, each block in the flowchart or block diagrams may represent a module, segment, or portion of instructions, which comprises one or more executable instructions for implementing the specified logical function(s). In some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown in succession may, in fact, be executed substantially concurrently, or the blocks may sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams and/or flowchart illustration, and combinations of blocks in the block diagrams and/or flowchart illustration, can be implemented by special purpose hardware-based systems that perform the specified functions or acts or carry out combinations of special purpose hardware and computer instructions.
As mentioned herein, an enhancement device according to some embodiments of the present invention may be installed on or be integral with a typical ETT, for sensing existence of excessive secretion and/or dryness in a patient's trachea lumen and/or a mouth, and for providing suction and/or wetness as needed.
Reference is now made to
Reference is now made to
In some embodiments of the present invention, device 100 is integral with an ETT device. For example, device 100 illustrated in
At a distal end of wrap 30, device 100 includes a trachea suction port 50. When installed on ETT 10, trachea suction port may be located just before balloon 16, in order to remove secretion, such as mucus, saliva or pus, before it reaches further in the trachea. Trachea suction port 50 may include, for example, one or more trachea suction inlets 51 for removal of secretion and/or mucus from the trachea, CO2 inlet for detection of CO2 in the trachea (shown, for example, in
Device 100 may also include a mouth pipe 32 for removal of secretion and/or mucus from the mouth, which may also include a moisture sensor for detecting of secretion fluid. In some embodiments, device 100 may include a liquid outlet 35, for providing liquid, possibly disinfecting fluid, into the mouth in order to avoid excessive dryness and/or infection, for example by spraying the fluid into the mouth. For example, the spray liquid can range from water to mouthwash or other medicated fluid. In some embodiments, device 100 may include one or more additional sensors at the distal end of wrap 30 or in the vicinity of mouth tube 32, such as, for example, a sensor of temperature, manometry, light, acidity level, sound, and/or any other suitable sensor.
At a proximal end, device 100 may include an outlet bundle 58, including secretion suction tubes 63 and 65, a liquid channel 64, a CO2 detection channel 66, sensor data wires 68, and/or any other suitable transmission pipe from and/or into device 100. Suction tubes 63 and 65, liquid channel 64, CO2 channel 66 and or sensor data wires 68 may be controlled by a hub 60, which may include a controller circuit 75 and/or a processor 79, described in more detail with reference to
For example, typical impedance values detected by the moisture sensors may range from more than 1000 Ohm for a dry environment to about 100 Ohm for wet environment, or some intermediate impedance value.
Suction tubes 63 and 65 may include a distal secretion suction tube and a mouth secretion suction tube, as shown in more detail in
During operation, wrap 30 is installed over ETT 10 and placed within a patient's body lumen, for example along the trachea through the mouth or nose. Reference is now made to
Controller circuit 75 may be controlled by processor 79, which may be external or internal to hub 60.
In order to prevent excessive dryness in the mouth, controller 75 may activate a liquid source 73 to provide liquid to liquid outlet 35 via liquid channel 64. Liquid source 73 may be activated in a predetermined time intervals, manually and/or according to sensor data. The liquid provided by source 73 may include water and/or an oral care solution, to avoid mouth infections. In some embodiments, hub 60 includes an air compressor 73a. Controller 75 may activate air compressor 73a to push air forcefully into liquid source 73, which as result pushes liquid forcefully through liquid channel 64, and create spray effect out of liquid outlet 35.
In some embodiments of the present invention, device 100 may detect air leakage from balloon 16. Hub 60 may include a CO2 level sensor 77. CO2 sensor 77 may receive a sample of air from the vicinity of balloon 16, via CO2 tube 66, and measure the CO2 level in the sample. As described below with reference to
Reference is now made to
In some embodiments of the present invention, additional or alternative suction port(s) 50 is located along wrap 30 to prevent liquid from entering through longitudinal opening 31. In some embodiments, wrap 30 includes along longitudinal opening 31 a liquid absorbing and/or expanding material, such as a sponge, as described in PCT publication WO 2011/117854 A3. Moisture sensor 53 may include detector electrode pair 52. Mouth pipe 32 may include a suction opening 33 for removal of secretion and/or mucus from the mouth and a moisture sensor for detecting of secretion fluid, including a detector electrode pair 34.
Wrap 30 may include a core 40 of thickness d, i.e. the thickness of wrap 30 between the external and internal perimeters of wrap 30. Within core 40 passes a plurality of longitudinal suction cavities, pipes and/or detector wires passing along wrap 30. As mentioned herein, the various suction cavities may accumulate and remove secretion and/or mucus from the mouth and/or from the trachea. Other pipes may be used for transmission of air sampling out of the trachea, transmission of liquids to the mouth and/or transmission of other suitable materials out of or into the trachea and/or the mouth as needed. In some embodiments, wrap 30 may include, within core 40, secretion suction cavities 41 and 42 for the trachea and mouth, respectively, a CO2 sampling pipe 44, liquid pipe 45, detector electrode pairs 34 and 52, and/or any other suitable pipes and/or wires.
Detector electrode pairs 34 and 52 may be used for impedance measurements in the trachea and/or mouth, for example for detection of moisture levels in the trachea and/or mouth and/or in order to identify secretion and/or excessive dryness. Based on the impedance measurements, a controller may determine whether to activate suction via cavities 41 and 42 and/or transmission of liquids via liquid pipe 45 to liquid outlet 35.
Reference is now made to
Reference is now made to
Reference is now made to
As described herein, electrode pair 34 and/or one or more other sensors may be located on tube 32, proximately to or at opening 33. As described herein, sensor data channels including detector electrode pairs 34 and 52, and mouth and distal suction cavities 42 and 41, may pass within core 40 of wrap 30 towards bundle 58 and/or hub 60. In some embodiments, CO2 sampling pipe 44, liquid pipe 45, and/or any other suitable pipes and/or wires, pass within core 40.
Reference is now made to
Material 90 takes the expanded state when absorbing liquid. Before insertion of wrap 30 into the trachea, as shown in
The methods as described above are used in the fabrication of integrated circuit chips.
The descriptions of the various embodiments of the present invention have been presented for purposes of illustration, but are not intended to be exhaustive or limited to the embodiments disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The terminology used herein was chosen to best explain the principles of the embodiments, the practical application or technical improvement over technologies found in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.
As used herein the term “about” refers to ±10%.
The terms “comprises”, “comprising”, “includes”, “including”, “having” and their conjugates mean “including but not limited to”. This term encompasses the terms “consisting of” and “consisting essentially of”.
The phrase “consisting essentially of” means that the composition or method may include additional ingredients and/or steps, but only if the additional ingredients and/or steps do not materially alter the basic and novel characteristics of the claimed composition or method.
As used herein, the singular form “a”, “an” and “the” include plural references unless the context clearly dictates otherwise. For example, the term “a compound” or “at least one compound” may include a plurality of compounds, including mixtures thereof.
The word “exemplary” is used herein to mean “serving as an example, instance or illustration”. Any embodiment described as “exemplary” is not necessarily to be construed as preferred or advantageous over other embodiments and/or to exclude the incorporation of features from other embodiments.
The word “optionally” is used herein to mean “is provided in some embodiments and not provided in other embodiments”. Any particular embodiment of the invention may include a plurality of “optional” features unless such features conflict.
Throughout this application, various embodiments of this invention may be presented in a range format. It should be understood that the description in range format is merely for convenience and brevity and should not be construed as an inflexible limitation on the scope of the invention. Accordingly, the description of a range should be considered to have specifically disclosed all the possible subranges as well as individual numerical values within that range. For example, description of a range such as from 1 to 6 should be considered to have specifically disclosed subranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6 etc., as well as individual numbers within that range, for example, 1, 2, 3, 4, 5, and 6. This applies regardless of the breadth of the range.
Whenever a numerical range is indicated herein, it is meant to include any cited numeral (fractional or integral) within the indicated range. The phrases “ranging/ranges between” a first indicate number and a second indicate number and “ranging/ranges from” a first indicate number “to” a second indicate number are used herein interchangeably and are meant to include the first and second indicated numbers and all the fractional and integral numerals therebetween.
It is appreciated that certain features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment. Conversely, various features of the invention, which are, for brevity, described in the context of a single embodiment, may also be provided separately or in any suitable subcombination or as suitable in any other described embodiment of the invention. Certain features described in the context of various embodiments are not to be considered essential features of those embodiments, unless the embodiment is inoperative without those elements.
Although the invention has been described in conjunction with specific embodiments thereof, it is evident that many alternatives, modifications and variations will be apparent to those skilled in the art. Accordingly, it is intended to embrace all such alternatives, modifications and variations that fall within the spirit and broad scope of the appended claims.
All publications, patents and patent applications mentioned in this specification are herein incorporated in their entirety by reference into the specification, to the same extent as if each individual publication, patent or patent application was specifically and individually indicated to be incorporated herein by reference. In addition, citation or identification of any reference in this application shall not be construed as an admission that such reference is available as prior art to the present invention. To the extent that section headings are used, they should not be construed as necessarily limiting. In addition, any priority document(s) of this application is/are hereby incorporated herein by reference in its/their entirety.
This application is a continuation of U.S. patent application Ser. No. 15/279,525 filed on Sep. 29, 2016 which claims the benefit of priority under 35 USC § 119(e) of U.S. Provisional Patent Application No. 62/333,625 filed on 9 May 2016, the contents of which are incorporated herein by reference in their entirety.
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| Child | 16571211 | US |
