SOLID PHASE SYNTHESIS OF A COMBINATORIAL LIBRARY

Information

• Research Project
• 2010482

• ApplicationId

  2010482

• Core Project Number

  R43CA072374

• Full Project Number

  1R43CA072374-01A1

• Serial Number

  72374

• FOA Number

• Sub Project Id

• Project Start Date

  5/1/1997 - 27 years ago

• Project End Date

  10/31/1997 - 27 years ago

• Program Officer Name

• Budget Start Date

  5/1/1997 - 27 years ago

• Budget End Date

  10/31/1997 - 27 years ago

• Fiscal Year

  1997

• Support Year

  1

• Suffix

  A1

• Award Notice Date

  4/4/1997 - 27 years ago

Organizations

• SOLID PHASE SCIENCES CORPORATION

Solid Phase Sciences Corporation (SPSC) proposes to produce a library of substituted acridine and pyridine based heterocycles. The library will consist of 5-10 milligrams each of a total of 384 compounds. SPSC will accomplish this by utilizing it's novel high-loading support and commercially available solvent delivery robot. Specifically, libraries will be made off of this high-loading support to separate the desired products from undesired starting material. A liquid handling robot will be used to add reagents and solvents. The goal of the Phase I effort will be to integrate the use of this high-loading support in solid phase synthesis with automated liquid handling into one automated system to produce a library composed of a series of acridine and pyridine based heterocyclic compounds for general screening.

IC Name

• Activity

  R43

• Administering IC

  CA

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  395

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  ZRG3

• Study Section Name

• Organization Name

  SOLID PHASE SCIENCES CORPORATION

• Organization Department

• Organization DUNS

• Organization City

  WATERTOWN

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  02172

• Organization District

  UNITED STATES