Soluble Complexes of DNA and Cationic Polymers for Gene Delivery

Information

• NSF Award
• 9907281

Owner

• UNIVERSITY OF NEBRASKA MEDICAL CENTER

• Award Id

  9907281

• Award Effective Date

  6/15/2000 - 24 years ago

• Award Expiration Date

  5/31/2004 - 20 years ago

• Award Amount

  $ 349,524.00

• Award Instrument

  Continuing grant

The objective of this project is to develop soluble complexes of DNA with cationic polymers for use in gene delivery to cells. The objectives described in the proposal are threefold: (1) to examine the efficacy of gene transfer of DNA/polycation complexes of various molecular architectures; (2) to study cellular mechanisms for delivery of the complexes into the cell; and (3) to evaluate the efficacy of gene transfer of DNA/polycation complexes containing attached proteins and peptides.

• Program Officer

  Fred G. Heineken

• Min Amd Letter Date

  6/20/2000 - 24 years ago

• Max Amd Letter Date

  4/16/2002 - 22 years ago

• ARRA Amount

• Name

  University of Nebraska Medical Center

• City

  Omaha

• State

  NE

• Country

  United States

• Address

  987835 Nebraska Medical Center

• Postal Code

  681987835

• Phone Number

  4025597456

• First Name

  Alexander

• Last Name

  Kabanov

• Email Address

  kabanov@email.unc.edu

• Start Date

  6/20/2000 12:00:00 AM

• Name

  Industrial Technology

• Code

  308000

• Text

  BIOTECH, BIOCHEM & BIOMASS ENG

• Code

  1491

• Text

  BIOMEDICAL ENGINEERING

• Code

  5345

• Text

  BIOTECH, BIOCHEM & BIOMASS ENG

• Code

  1491

• Text

  BIOMEDICAL ENGINEERING

• Code

  5345

• Text

  BIOPROCESSING/BIOMOLECULAR MATERIALS

• Code

  9181

• Text

  BIOTECHNOLOGY