Spectral interferometry for in vivo imaging

Information

  • Research Project
  • 6782661
  • ApplicationId
    6782661
  • Core Project Number
    R44HL069108
  • Full Project Number
    5R44HL069108-03
  • Serial Number
    69108
  • FOA Number
  • Sub Project Id
  • Project Start Date
    5/1/2001 - 23 years ago
  • Project End Date
    1/31/2007 - 17 years ago
  • Program Officer Name
    BUXTON, DENIS B.
  • Budget Start Date
    8/1/2004 - 20 years ago
  • Budget End Date
    1/31/2007 - 17 years ago
  • Fiscal Year
    2004
  • Support Year
    3
  • Suffix
  • Award Notice Date
    6/10/2004 - 20 years ago

Spectral interferometry for in vivo imaging

DESCRIPTION (provided by applicant): The objective of this project is to develop an intravascular optical imaging device that will aid in the diagnosis of atherosclerosis. According to statistics compiled by the American Heart Association, cardiovascular disease affects over 61 million Americans and is the leading cause of death in the United States. Atherosclerosis is indicated as a primary factor in three fourths of deaths resulting from cardiovascular disease. It is now recognized that the danger of atherosclerosis is not primarily due to narrowing of the arteries. Many coronary events and strokes are caused by atherosclerotic plaques that rupture. It is important that the cardiologist be able to assess the risk of plaque rupture when diagnosing and treating persons with atherosclerosis. The risk of plaque rupture is related to its structure and composition. Our spectral imaging technology is capable of resolving the small structural features important to identifying vulnerable plaques. Currently available imaging tools (angioscopy, MRI, intravascular ultrasound) do not provide the high spatial resolution needed for this application. An intravascular device based on our technology, which combines spatial imaging for structural detail and spectroscopic measurement for plaque composition, will provide important information for the cardiologist making risk assessments and choosing the best course of treatment.

IC Name
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
  • Activity
    R44
  • Administering IC
    HL
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    337345
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    837
  • Ed Inst. Type
  • Funding ICs
    NHLBI:337345\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    SOUTHWEST SCIENCES, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    SANTA FE
  • Organization State
    NM
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    87505
  • Organization District
    UNITED STATES