Claims
- 1. The crystalline, stable form of (6R,7R)-7-[[2-(2-amino-4-thiazolyl)-(Z)-2-(1-tert.butoxycarbonyl-1-methylethoxy)imino]acetamido]-3-(1-pyridiniummethyl)-3-cephem-4-carboxylate (ceftazidime-t-butylester) of formula ##STR6## having the X-ray spectrum
- ______________________________________ d (.ANG.) I______________________________________ 17.0 w 15.5 m 5.9 w 5.0 w 4.15 w 3.84 w 3.3 w______________________________________ w = weak m = medium
- (.alpha.-form).
- 2. The crystalline, stable form of (6R,7R)-7-[[2-(2-amino-4-thiazolyl)-(Z)-2-(1-tert.butoxycarbonyl-1-methylethoxy)imino]acetamido]-3-(1-pyridiniummethyl)-3-cephem-4-carboxylate (ceftazidime-t-butylester) of formula I, having the X-ray spectrum
- ______________________________________ d (.ANG.) I______________________________________ 22.0 m 10.0 w 8.5 m 7.3 w 6.7 m 5.9 md 5.6 m 5.3 wd 4.2 w 3.94 w 3.82 w 3.7 w 3.3 w______________________________________ w: weak m: medium d: diffuse
- (.beta.-form).
- 3. The ceftazadime-t-butyl ester of claim 2 having a purity of at least 97%.
Parent Case Info
This is a continuation of application Ser. No. 07/382,144, filed Jun. 27, 1989, now abandoned, which in turn is a continuation of application Ser. No. 07/211,536, filed May 5, 1988, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4497956 |
Looker |
Feb 1985 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
0160565 |
Nov 1985 |
EPX |
0166580 |
Jan 1986 |
EPX |
Continuations (2)
|
Number |
Date |
Country |
Parent |
382144 |
Jun 1989 |
|
Parent |
211536 |
May 1988 |
|