The present invention relates to a stopper for a container, in particular a stopper for containers that are used in the analytical and diagnostic field. The container can be in particular a bottle or a cuvette.
For the purpose of analyzing a substance, in particular a liquid, for example blood, it is necessary that the substance to be analyzed is removed from the container or that further substances are introduced into the container. Depending on the analysis that is to be performed, it is possible that only a partial quantity of the substance stored in the container is removed and supplied for analysis or to the analysis apparatus. It may also be the case that, for analysis purposes, substance is removed several times from the container or substances are introduced several times into the container. Generally, the substance that is to be analyzed is removed from the container by means of a pipetting device or a syringe or further substances are introduced into the container. The procedure of removing the substance from the container can take place in a fully automated manner, for example by means of an automatic pipetting apparatus. As regards the substance to be analyzed, and in particular with respect to repeated removal of substance from the container or repeated introduction of substance into the container, it is necessary to avoid evaporation of the substance located in the container and to avoid admission of foreign bodies into the container and thus into the substance that is to be analyzed. It is therefore necessary to close or at least partially cover the opening of the container, but at the same time to permit simple removal of the substance from the container.
For this purpose, it is known to cover the container with a thin membrane, said membrane being slit so that it can be easily pierced through by the removal device, for example a pipet tip or hollow needle. The production of such covers generally requires subsequent slitting of the membrane, which necessitates an additional operating step or correspondingly complicated tooling. A membrane of this kind can be, for example, a constituent part of a screw-on lid that is screwed onto the container. However, handling and production are complicated, since different materials generally have to be used for the membrane and for the rest of the lid. Moreover, the membrane has to be slit in an additional operating step and connected to the lid.
EP 0 097 591 A1 discloses a stopper for a container, said stopper having a cover portion that can be pierced through by means of a pipet tip for the purpose of introducing substance into the container or removing substance from the container. At a front end in the direction of insertion of the stopper, i.e. at the end directed toward the interior of the container, the cover portion has a plurality of slits, as a result of which segments are formed. The segments bear on one another in a basic state and form a closed cover portion. The slits allow the cover portion to be pierced through axially by means of the pipet tip, with the segments being deformed radially outward for this purpose. The segments are pre-tensioned in such a way that, after the pipet tip has been pulled out of the cover portion, the segments return to their basic state and thus again close the container opening. A disadvantage of the stopper known from EP 0 097 591 A1 is that, during the insertion of the stopper, an undesired deformation of the segments can occur as a consequence of the stopper interacting with a container wall. Moreover, production of the stopper is difficult on account of the slits that have to be made. Moreover, when force is exerted on the cover portion, there is the danger of changing the position of the stopper in the container.
The object of the present invention is to make available a stopper for a container, which stopper reliably prevents evaporation of substance from a container or entry of foreign bodies into the container, but nonetheless permits simple introduction of substance into the container or removal of substance from the container. In addition, the stopper is intended to be particularly easy to produce, in particular by means of injection molding. The stopper is intended in particular to be able to be produced without the need for subsequent formation of slits.
The stopper according to the invention has a jacket portion insertable into the container, wherein the jacket portion has a through-opening formed in an axial direction. The stopper has at least two segments, wherein the respective segment has a free end. A first portion of the free end of the respective segment forms a subregion of the jacket portion, and a second portion of the free end of the respective segment protrudes radially inward in relation to the jacket portion. A third portion of the free end of the respective segment protrudes radially outward in relation to the jacket portion. The second portions form a cover portion that can be pierced through in the axial direction and that closes the through-opening, and the third portions form a bearing portion of the stopper.
By virtue of the fact that the respective segment has a free end, the segments are deformable or movable independently of one another in the region of the free ends. In particular, the second portions of the free end of the respective segment are deformable independently of the second portions of the free ends of the other segments, as a result of which the cover portion can be pierced through axially, for example by means of a pipet tip or a needle or other removal element/introduction element.
By virtue of the fact that the third portions protrude radially outward in relation to the jacket portion and form a bearing portion of the stopper, the stopper can be positioned relative to the container in a simple way since, during the insertion of the stopper into the container, the bearing portion forms a stop which, during the insertion of the stopper into the container, comes to bear axially on a container edge enclosing a container opening and to this extent prevents further insertion of the stopper into the container or limits the depth of insertion. The bearing portion is also advantageous as regards the piercing through of the cover portion by means of an external device, for example a pipet tip, since an axial force has to be exerted on the cover portion during the piercing. The bearing portion prevents an undesired further insertion of the stopper into the container and thus ensures reliable piercing of the cover portion.
As regards the second portions, it is considered particularly advantageous if the second portions are deformable independently of the other portions of the respective segment.
It is considered advantageous if the second portions have a lesser material thickness than the third portions. This favors a deformation of the second portions relative to a deformation of the bearing portions, when an axial force is exerted on the cover portion.
It is considered advantageous if the cover portion is formed at a rear end of the jacket portion, as seen in the direction of insertion of the stopper. This prevents a situation where foreign bodies accumulate on the jacket portion in a region of the through-opening directed away from the interior of the container and pass into the interior of the container when the cover portion is pierced through.
The segments are preferably connected, at the end of the segments, to adjacent segments.
It is considered particularly advantageous if the segments are connected to each other in the region of an end of the jacket portion directed away from the bearing portion. The segments are thereby connected to each other in the region of a front end of the jacket portion, as seen in the direction of insertion of the stopper.
The region of the jacket portion in which the segments are connected to each other is preferably configured as a closed annular structure. This ensures a particularly high degree of stability of the connection of the segments and of the stopper as a whole. A closed annular structure is also considered advantageous with regard to ejection of the stopper from an injection molding tool.
The segments preferably have a web-like configuration.
In one embodiment, provision is made that the jacket portion has a region with a cross section that widens in the direction of the bearing portion, or the jacket portion has a cross section that widens in the direction of the bearing portion. It is considered particularly advantageous if the widening is conical. On account of the widening cross section, a radially inward deformation of the free end of the respective segment is facilitated during the insertion of the stopper into the container. On account of the radially inward deformation, particularly good sealing of the container opening is achieved and, moreover, a force fit between the stopper and a container wall is brought about, as a result of which the stopper is held particularly securely in the container.
The cover portion and/or the bearing portion are/is preferably configured at the end of the jacket portion.
It is considered particularly advantageous if the cover portion and the bearing portion are configured in the same plane.
The cover portion and/or the bearing portion are/is preferably configured perpendicularly with respect to the axial direction.
In another embodiment, the cover portion and/or the bearing portion are/is formed at a rear end of the jacket portion, as seen in the direction of insertion of the stopper.
It is considered advantageous if a ratio of an axial extent of the first portion of the segments to an axial extent of the jacket portion is at least 80 percent. With such a length ratio, it is possible, with relatively low bending forces in the connection region between the segment and the rest of the jacket portion, to achieve quite a considerable radially inward displacement of the end of the segment directed away from the connection region. This has an advantageous effect on the segments deforming without being destroyed.
It is considered particularly advantageous if the free ends of adjacent segments are spaced apart from one another in a basic state of the stopper. The basic state is understood here as a state of the stopper when free of external forces.
In another embodiment, provision is made that a minimum distance between adjacent segments is at least 0.8 mm, in particular at least 1.0 mm. These distances are advantageous for production of the stopper by injection molding.
The stopper is preferably configured with radial symmetry.
In a particularly advantageous embodiment, provision is made that the respective segment is configured as a subregion of a rotation body, wherein a rotation axis assignable to the rotation body of the respective segment runs outside an axis of symmetry of the stopper. Preferably, the respective rotation axis runs outside of and parallel to the axis of symmetry of the stopper. This embodiment has the advantage that, during a radially inward deformation of the segments, subregions of the segments, particularly the second and third regions of the segments, form a closed, rotationally symmetrical body, as a result of which a particularly good sealing effect is achieved.
In another embodiment, the stopper has at least three segments, preferably at least four segments, in particular at least six segments. The force that has to be applied in order to pierce through the cover portion can be easily adapted by way of the number of segments. The greater the number of segments the stopper has, the less the force that has to be applied.
It is considered particularly advantageous if the segments are deformed radially inward, preferably elastically, during the insertion of the stopper into the container.
In another embodiment, provision is made that the second portions form a closed surface upon radially inward deformation of the segments.
It is considered particularly advantageous if the stopper is integrally formed in one piece.
It is preferable for the segments, in particular the entire stopper, to be produced from an elastic material. For example, the elastic material can be a thermoplastic elastomer, for example polyethylene.
It is considered particularly advantageous if, in a plan view in the axial direction, the second portions form sectors of a circle. It is also considered advantageous if, in a plan view in the axial direction, the third portions form ring sectors of a ring.
In another embodiment, provision is made that, in a cross section of the jacket portion in the connection region of the segments, the respective segment forms an arc of a circle.
It is entirely conceivable to use the stopper in combination with a lid that can be connected to the container. For this purpose, the lid has an opening, for access to the cover portion, wherein the lid secures the stopper against being pulled out of the container.
In the accompanying drawing figures, the invention is described in more detail on the basis of various exemplary embodiments, but without being limited to the particular embodiments shown described and shown herein.
The stopper 1 has a jacket portion 3 insertable into the container 2, the jacket portion 3 having a through-opening 4 formed in an axial direction Z. The stopper 1 in the present embodiment has three segments 5, wherein the respective segment 5 has a free end. The segments 5 are connected to one another at their other end, in the present embodiment in the region of a front end of the jacket portion 3 in the direction of insertion of the stopper 1. The region in which the segments 5 are connected to one another is configured as a closed annular structure 12, as can be seen in particular from
As can be seen in particular from
As can be seen in particular from
The cover portion 9 and the bearing portion 10 are configured in the same plane, wherein the cover portion 9 and the bearing portion 10 are formed, at the end of the jacket portion 3, on a rear end 15 of the stopper 1 as seen in the direction of insertion of the stopper 1.
The cover portion 9 and the bearing portion 10 are perpendicular to the axial direction Z. As can be seen in particular from
As can be seen in particular from
In a plan view in the axial direction Z, the second portions 7 form sectors of a circle and the third portions 8 form ring sectors of a ring.
The second embodiment of the stopper 1 shown in
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19212483 | Nov 2019 | EP | regional |
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Number | Date | Country | |
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20210163185 A1 | Jun 2021 | US |