STRONTIUM COMPOSITIONS FOR BONES

Abstract

A composition of matter includes an effective amount of strontium carbonate for affecting bone metabolism. The composition is substantially free of calcium to avoid absorption competition in the digestive tract. The composition is also preferably substantially free of chelating agents, phosphate, phytic acid, oxalates, insoluble fibers, and non-strontium divalent cations or other materials that compete with strontium ions for absorption in the human digestive tract. Other ingredients are optionally added to increase strontium absorption or for their independent positive effective on bone health, including for example vitamin D and vitamin K, quercetin dihydrate, and hesperidin. The composition is preferably administered as a chewable food by blending with a chewable food matrix to form a palatable food that is readily consumed.

Description

Claims

1. A composition of matter, comprising an effective amount of strontium carbonate for affecting bone metabolism, and being substantially free of calcium.

2. The composition of claim 1, wherein the composition comprises sufficient strontium carbonate to provide at least about 100 mg of elemental strontium.

3. The composition of claim 1, wherein the composition comprises sufficient strontium carbonate to provide from about 500 mg to about 1500 mg elemental strontium.

4. The composition of claim 1, further comprising the addition of an effective amount of one or more compounds selected from the group consisting of lysine, lactose, and arginine to facilitate strontium absorption.

5. The composition of claim 1, which is substantially free of chelating agents.

6. The composition of claim 1, which is substantially free of phosphate, phytic acid, oxalates, and insoluble fibers.

7. The composition of claim 1, which is substantially free of non-strontium divalent cations or other materials that compete with strontium ions for absorption in the human digestive tract.

8. The composition of claim 1, further comprising from about 100 international units to about 800 international units of vitamin D3.

9. The composition of claim 1, further comprising from about 0.001 grams to about 10 grams of vitamin K.

10. The composition of claim 1, further comprising: 0.1 mg to 1000 mg quercetin dihydrate; and0.1 mg to about 1000 mg hesperidin.

11. The composition of claim 1, comprising a dosage form selected from the group consisting of a beverage, a tablet, a capsule, a powder, and a chewable food.

12. A composition of matter, comprising: a chewable food-stuff matrix substantially lacking in calcium, the chewable food-stuff matrix comprising an effective amount of strontium carbonate for affecting bone metabolism.

13. The composition of claim 12, which is substantially free of chelating agents, phosphate, phytic acid, oxalates, insoluble fibers, and non-strontium divalent cations or other materials that compete with strontium ions for absorption in the human digestive tract.

14. The composition of claim 12 further comprising: an effective amount of vitamin D3 for bone building activity; andan effective amount of at least one of quercetin dihydrate and hesperidin for bone building activity.

15. The composition of claim 14 wherein the vitamin D3 comprises about 100 and 800 international units.

16. The composition of claim 14, further comprising from about 0.001 grams to about 10 grams vitamin K.

17. The composition of claim 12, further comprising: from about 0.1 mg to about 1000 mg quercetin dihydrate; andfrom about 0.1 mg to about 1000 mg hesperidin.

18. The composition of claim 12, wherein the chewable food-stuff matrix comprises a bulking agent, a vegetable based oil, a natural flavoring additive, a sweetener, and at least one of an emulsifier and a surfactant.

19. The composition of claim 12, wherein the strontium carbonate is from about 18 to about 21% by weight of the composition.

20. The composition of claim 12, wherein the composition comprises sufficient strontium carbonate to provide at least about 100 mg of elemental strontium.

21. The composition of claim 12, wherein the composition comprises an amount of strontium carbonate to provide from about 500 mg to about 1500 mg strontium carbonate.

22. The composition of claim 12, wherein the composition comprises an amount of strontium carbonate to provide from about 600 mg to about 700 mg of elemental strontium.

23. The composition of claim 12, the composition having a weight of from about 1.5 grams to about 20 grams.

24. The composition of claim 12, further comprising the an effective amount of one or more compounds selected from the group consisting of lysine, lactose, and arginine to facilitate strontium absorption.

25. A method for improving bone health in a mammal, the method comprising administering an effective dose of strontium carbonate, in the absence of amounts of calcium that would interfere with the uptake of the strontium, for improving bone health in a mammal.

26. The method of claim 25, wherein the effective dose of strontium carbonate comprises an effective dose of strontium carbonate to increase adult stature by increasing epiphyseal bone growth.

27. The method of claim 25, wherein the effective dose of strontium carbonate comprises an effective dose of strontium carbonate for assisting in the healing of bone fractures.

28. The method of claim 25, wherein the effective dose of strontium carbonate comprises an effective dose of strontium carbonate for treating metabolic bone disease, in the absence of amounts of calcium that would interfere with the uptake of the strontium.