STTR Phase I: Nanoshell-Based Cancer Therapy

Information

  • NSF Award
  • 0319962
Owner
  • Award Id
    0319962
  • Award Effective Date
    7/1/2003 - 21 years ago
  • Award Expiration Date
    6/30/2004 - 20 years ago
  • Award Amount
    $ 99,994.00
  • Award Instrument
    Standard Grant

STTR Phase I: Nanoshell-Based Cancer Therapy

This Small Business Technology Transfer (STTR) Phase I will develop a novel, nanotechnology-based cancer therapy. This therapy, nanoshell-based thermal ablation (NBTA), holds the promise as a significant new therapeutic tool for the treatment of otherwise inoperable cancers or neoplasms where surgery is accompanied by a high probability of morbidity or mortality. The therapy will utilize proprietary nanoshells to convert externally applied near-infrared (nIR) light into localized heat to destroy targeted cancer cells, minimizing damage to surrounding tissue and avoiding the long-term effects of radiation therapy or chemotherapy. Specific goals of this STTR project include (i) understanding biodistribution and clearance of nanoshells, (ii) understanding tumor uptake of nanoshells, and (iii) assessment of the survival time of animals with cancers that have been treated with nanoshells.<br/><br/>The commercial application of this project will be in cancer therapy. NBTA will lead to an FDA regulated device comprised of nanoshells and a light delivery system (laser). The company will partner with a laser manufacturer, and with a marketing and sales partner, for distribution of the product.

  • Program Officer
    Om P. Sahai
  • Min Amd Letter Date
    6/20/2003 - 21 years ago
  • Max Amd Letter Date
    12/9/2003 - 21 years ago
  • ARRA Amount

Institutions

  • Name
    NANOSPECTRA BIOSCIENCES, INC.
  • City
    HOUSTON
  • State
    TX
  • Country
    United States
  • Address
    8285 EL RIO ST STE 150
  • Postal Code
    770544654
  • Phone Number
    7138422720

Investigators

  • First Name
    Dennis
  • Last Name
    O'Neal
  • Email Address
    poneal@latech.edu
  • Start Date
    12/9/2003 12:00:00 AM
  • First Name
    Daniel
  • Last Name
    Watkins
  • Email Address
    dwatkins@nanospectra.com
  • Start Date
    6/20/2003 12:00:00 AM
  • End Date
    12/09/2003

FOA Information

  • Name
    Technology Transfer
  • Code
    110000
  • Name
    Health
  • Code
    203000