Aldritt, Susan M., et al., “Purification and Characterization of Guanine Phosphoribosyltransferase From Giardia Lamblia”, The Journal of Biological Chemistry, vol. 261:8528-8533 (1986). |
Aronov, Alex M., et al., Phthalimide Resin Reagent for Efficient Mitsunobu Amino-Dehydroxylation, Tetrahedron Letters, vol. 39:4947-4950 (1998). |
Aronov, Alex M., et al., Rational Design of Selective Submicromolar Inhibitors of Tritrichomonas foetus Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase, Biochemistry, vol. 39(16) Apr. 25, 2000. |
Beck, Joanne T., et al., “The Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase From Tritrichomonas Foetus Has Unique Properties”, Molecular and Biochemical Parasitology, vol. 60:187-194 (1993). |
Chin, Marian S., et al., Isolation, Sequencing and Expression of the Gene Encoding Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase of Tritrichomonas Foetus, Molecular and Biochemical Parasitology, vol. 63:221-230 (1994). |
Eads, et al., “The Crystal Structure of Human Hypoxanthine-Guanine Phosphoribosyltransferase with Bound GMP”, Cell vol. 78:325-334 (1994). |
Gutteridge, W.E., “Designer Drugs: Pipe-Dreams or Realities?”, Parasitology, vol.114:S145-S151 (1997). |
Hague, Tasir S., et al., “Potent, Low-Molecular-Weight Non-Peptide Inhibitors of Malarial Aspartyl Protease Plasmepsin II”, Journal of Medicinal Chemistry, vol. 42:1428-1440 (1999). |
Hunter, W.N., A Structure-Based Approach to Drug Discovery; Crystallography and Implications for the Development of Antiparasite Drugs, Parasitology, vol.114:S17-S29 (1997). |
Kanaaneh, Jamil, et al., Differntial Inhibitory Effects of GMP-2′,3′-Dialdehyde on Human and Schistosomal Hypoxanthine-Guanine Phosphoribosyltransferases, Eur. J. Biochem., vol. 223:595-601 (1994). |
Lapinski, Christopher A., et al., “Experimental and Computational Approaches to Estimate Solubility and Permeability in Drug Discovery and Development Settings”, Advanced Drug Delivery Reviews vol. 23:3-25 (1997). |
Schumacher, Maria A., et al., “Crystal Structures of Toxoplasma Gondii HGXPRTase Reveal the Catalytic Role of a Long Flexible Loop”, Nature Structural Biology, vol. 3:881-887 (1996). |
Shi, Wuxian, et al., The 2.0 Å Structure of Human Hypoxanthine-Guanine Phosphoribosyltransferase in Complex wth a Transition-State Analog Inhibitor, Nature Structural Biology, vol. 6:588-593 (1999). |
Shi, Wuxian, et al., The 2.0 Å Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor, Biochemistry, vol. 38:9872-9880 (1999). |
Sommer, Jürg M., et al., “Cloning, Expression and Characterization of an Unusual Guanine Phosphoribosyltransferase from Giardia Lamblia”, Molecular and Biochemical Parasitology, vol. 78:185-193 (1996). |
Somoza, John R., et al., “Rational Design of Novel Antimicrobials: Blocking Purine Salvage in a Parasitic Protozoan”, Biochemistry, vol. 37(16):5344-5348 (1998). |
Somoza, John R., et al., “Crystal Structure of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from the Protozoan Parasite Tritrichomonas Foetus”, Biochemistry, vol. 35:7032-7040 (1996). |
Wang, C.C., “Current Problems in Anti-Parasite Chemotherapy”, Trends in Biochemical Sciences, vol. 7:354-356 (1982). |
Wang, C.C., “Parasite Enzymes as Potential Targets for Antiparasitic Chemotherapy”, Journal of Medicinal Chemistry, vol. 27:1-9 (1984). |
Wang, C.C., et al., “Purine Salvage by Tritrichomonas Foetus”, Molecular and Biochemical Parasitology, vol. 8:325-337 (1983). |
Wang, C.C. “Validating Targets for Antiparasite Chemotherapy”, Parasitology, vol. 114:S31-S44 (1997). |
Yuan, Ling, et al., Steady-State Kinetics of the Schistosomal Hypoxanthine-Guanine Phosphoribosyltransferase, Biochemistry, vol.31:806-810 (1992). |