Claims
- 1. A compound having the formula ##STR3## wherein A is selected from ##STR4## wherein R.sub.1 and R.sub.2 are independently selected from straight or branched alkyloxy of from one to four carbon atoms; and
- wherein R is straight or branched alkyl of from one to four carbon atoms.
- 2. A compound as defined in claim 1 having the name (Z)-N-(2,4,6-trimethoxyphenyl)-9-octadecenamide.
- 3. A compound as defined in claim 1 having the name (Z,Z)-N-(2,4,6-trimethoxyphenyl)-9,12-octadecadienamide.
- 4. A compound as defined in claim 1 having the name (Z,Z,Z)-N-(2,4,6-trimethoxyphenyl)-9,12,15-octadecatrienamide.
- 5. A pharmaceutical composition useful for inhibiting the intestinal absorption of cholesterol comprising an ACAT-inhibitory effective amount of a compound as defined by claim 1 in combination with a pharmaceutically acceptable carrier.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of copending application Ser. No. 843,420 filed Mar. 24, 1986, now abandoned.
Foreign Referenced Citations (7)
Number |
Date |
Country |
873365 |
Sep 1979 |
BEX |
4103698 |
Mar 1966 |
JPX |
6515757 |
Jun 1966 |
NLX |
1051286 |
Dec 1966 |
GBX |
1057742 |
Feb 1967 |
GBX |
1121667 |
Jul 1968 |
GBX |
1123004 |
Aug 1968 |
GBX |
Non-Patent Literature Citations (6)
Entry |
Chemical Abstracts, vol. 65, 13459g, (1966). |
Derwent Abstract of Japanese Patent Document JA-7210702 (1968). |
Derwent Abstract of Japanese Patent Document JA 7109330 (1965). |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
843420 |
Mar 1986 |
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