Claims
- 1. A compound selected from a base of the formula ##SPC11##
- wherein m is a positive whole integer of from 1 to 3; n is a positive whole integer of from 3 to 7; each of R and R.sup.1 is selected from the group consisting of hydrogen, a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a halogen atom, trifluoromethyl, trifluoromethylthio, trifluoromethoxy, phenyl, phenoxy, a lower alkoxy group of from 1 to 4 carbon atoms, with the proviso that both R and R.sup.1 are not hydrogen and with the proviso that when m is equal to 1 and one of R and R.sup.1 is hydrogen, the other of R or R.sup.1 is not lower alkoxy of from 1 to 4 carbon atoms; and pharmaceutically acceptable acid addition salts thereof.
- 2. A compound of claim 1 wherein each of R and R.sup.1 is selected from the group consisting of a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a halogen atom, trifluoromethyl, trifluoromethylthio trifluoromethoxy, phenyl, phenoxy and a lower alkoxy group of from 1 to 4 carbon atoms.
- 3. A compound of claim 2 wherein n is the integer 4 or 5.
- 4. A compound of claim 3 which is 2-[(.alpha.-{p-chlorophenyl}-m-trifluoromethylbenzyl)imino]hexahydroazepine and pharmaceutically acceptable acid addition salts thereof.
- 5. A compound of claim 1 wherein R is hydrogen and R.sup.1 is selected from the group consisting of a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a halogen atom, trifluoromethyl, trifluoromethylthio, trifluoromethoxy, phenyl, phenoxy, and a lower alkoxy group of from 1 to 4 carbon atoms with the proviso that when m is equal to 1, R.sup.1 is not a lower alkoxy group of from 1 to 4 carbon atoms.
- 6. A compound of claim 5 wherein n is the integer 4 or 5.
- 7. A compound of claim 6 which is 2-[(p-chloro-.alpha.-phenylbenzyl)imino]hexahydroazepine and pharmaceutically acceptable acid addition salts thereof.
- 8. A compound of claim 6 which is hexahydro-2-[(m-{trifluorometyl}-.alpha.-phenylbenzyl)imino]azepine and pharmaceutically acceptable acid addition salts thereof.
- 9. A compound of claim 6 which is hexahydro-2-[(o-methyl-.alpha.-phenylbenzyl)imino]azepine and pharmaceutically acceptable acid addition salts thereof.
Parent Case Info
This application is a continuation in part of copending application Ser. No. 244,873 filed, Apr. 17, 1972, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3725435 |
Poos |
Apr 1973 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
1,210,848 |
Nov 1970 |
UK |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
244873 |
Apr 1972 |
|