Claims
- 1. A compound of the formula or its pharmaceutically acceptable salt, whereinW is —S—CH2—; R1, R2 and R3 are independently hydrogen, C1-C3 alkyl C1-C3 alkyl C1-C3 alkoxy or halo C1-C3 alkyl, provided that when W is methylene, both R2 and R3 are not hydrogen; X is halo, C1-C3 alkoxy, C1-C3 alkyl, halo C1-C3 alkoxy or C1-C3 alkenyl; Y is imino or oxy; Q is oxygen or sulfur; and T is (2S,3S)-2-diphenylmethylquinuclidin-3-yl, (2S,3S)-2-phenylpiperidin-3-yl or (2S,3S)-2-diphenylmethyl-1-azanorbornan-3-yl.
- 2. A compound according to claim 1, wherein X is C1-C3 alkoxy or halo C1-C3 alkoxy; Y is imino; and T is (2S,3S)-2-diphenylmethylquinuclidin-3-yl or (2S,3S)-2-phenylpiperidin-3-yl.
- 3. A compound according to claim 2, wherein R1 is methyl, isopropyl, methoxy or 2,2,2-trifluoroethyl; R2 and R3 are independently hydrogen, methyl or trifluoromethyl; and X is methoxy, isopropoxy, difluoromethoxy or trifuluoromethylmethoxy.
Parent Case Info
This is a division of application Ser. No. 08/983,004 now U.S. Pat. No. 6,180,647; filed Mar. 25, 1998 which is a 371 of PCT/IB96/00434 filed May 9, 1996.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5646144 |
Schilling et al. |
Jul 1997 |
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