Claims
- 1. A compound having the formula
- A(CH.sub.2)n O--B
- wherein A is a group having the formula ##STR30## wherein X is --N--;
- Z is ##STR31## R.sup.1 is hydrogen, lower alkyl or phenyl; R.sup.2 is hydrogen or lower alkyl; or
- R.sup.1 and R.sup.2 taken together from a benzene ring;
- R.sup.3 is hydrogen or alkyl
- n is 1-2;
- B is ##STR32## wherein Y is OR.sup.5 or N(OH)R.sup.8 ;
- R.sup.4 and R.sup.5 are each independently hydrogen or lower alkyl;
- R.sup.6 is hydrogen, halo or nitro;
- R.sup.7 is ##STR33## R.sup.8 is lower alkyl; m is 0-3;
- and the pharmacologically acceptable salts thereof.
- 2. The compound of claim 1, having the name N-hydroxy-N,.alpha.-dimethyl4'---4-acetamide.
- 3. The compound of claim 1, having the name 2--N-hydroxy-N-methyl-4-acetamide.
- 4. The compound of claim 1, having the name N-hydroxy-N--1-acetamide.
Parent Case Info
This is a division of application Ser. No. 07/891,537 filed Jun. 1, 1992, which is U.S. Pat. No. 5,218,124 and is a continuation-in-part of U.S. patent application Ser. No. 07/661,733, filed Feb. 27, 1991 now abandoned which is a continuation-in-part of U.S. patent application Ser. No. 07/427,677, filed Oct. 27, 1989, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4268670 |
Wehling et al. |
May 1981 |
|
Non-Patent Literature Citations (4)
Entry |
Chemical Abstracts, vol. 114, No. 25, Abstract 247, 270n, Jun. 24, 1991. |
Chemical Abstracts, vol. 108, No. 23, Abstract 198, 210h, Jun. 6, 1988. |
Cerrena et al., Coll. Czech Chem. Commun, 54(7) pp. 1966-1978, 1989. |
Winkelmann et al. Arzneim-Forsch, 28(5) pp. 739-749, 1978. |
Divisions (1)
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Number |
Date |
Country |
Parent |
891537 |
Jun 1992 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
427677 |
Oct 1989 |
|