Claims
- 1. A compound of the formula ##STR17## wherein Q is S;
- Y is N;
- R.sub.1 is hydrogen, loweralkyl, loweralkynyl, loweralkenyl, arylloweralkyl, loweralkoxycarbonylaminoloweralkylcarbonyl, arylloweralkoxycarbonylaminoloweralkylcarbonyl, aminoloweralkylcarbonyl, loweralkoxycarbonyl or acyl; the term acyl in each occurence meaning a substituent having the formula ##STR18## the term aryl in each occurrence meaning a phenyl group substituted with 0.1 or 2 substituents each of which being independently loweralkyl, loweralkoxy, halogen or trifluoromethyl:
- R.sub.2 is hydrogen or loweralkyl;
- R.sub.3 is hydrogen or loweralkyl;
- X is hydrogen, loweralkyl or halogen, and n is 0 or 1; or a pharmaceutically acceptable acid addition salt thereof.
- 2. The compound as defined in claim 1 which is 5-(4-pyridinylamino)-1,2-benzisothiazole.
- 3. The compound as defined in claim 1 which is 5-(propyl-4-pyridinylamino)-1,2-benzisothiazole.
- 4. The compound as defined in claim 1 which is N-(1,2-benzisothiazol-5-yl)-N-(4-pyridinyl)-2-aminoacetamide.
- 5. A pharmaceutical composition which comprises a compound as defined in claim 1 in an amount effective for treating depression and a suitable carrier therefor.
- 6. A method of treating a patient in need of relief from depression which comprises administering to such a patient an effective amount of a compound as defined in claim 1.
Parent Case Info
This is a continuation of application Ser. No. 764,031 filed Sep. 23, 1991, now U.S. Pat. No. 5,185,350 issued Feb. 9, 1993.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4970219 |
Effland et al. |
Nov 1990 |
|
5006537 |
Effland et al. |
Apr 1991 |
|
Divisions (1)
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Number |
Date |
Country |
Parent |
764031 |
Sep 1991 |
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